Peripheral blood expression of nuclear factor-κB-regulated genes is associated with rheumatoid arthritis disease activity and responds differentially to anti-tumor necrosis factor-α versus methotrexate

Journal of Rheumatology

Volumn 34, Issue 9, 2007, Pages 1817-1822

  Parker, Alex ^a   Izmailova, Elena S ^a   Narang, Jigna ^a   Badola, Sunita ^a   Le, Tinh ^a   Roubenoff, Ronenn ^a   Ginsburg, Geoffrey S ^b   Maier, Agnes ^c   Coblyn, Jonathan S ^c   Shadick, Nancy A ^c   Weinblatt, Michael E ^c  

^a MILLENNIUM PHARMACEUTICALS INC   (United States)

^b DUKE UNIVERSITY   (United States)

^c BRIGHAM AND WOMEN S HOSPITAL   (United States)

Author keywords

Methotrexate; Nuclear factor B; Rheumatoid arthritis; Transcript expression analysis; Transcription factor; Tumor necrosis factor inhibitor

Indexed keywords

ADALIMUMAB; AQUAPORIN 3; BIOLOGICAL MARKER; C REACTIVE PROTEIN; CALGRANULIN; CORTICOSTEROID; DISEASE MODIFYING ANTIRHEUMATIC DRUG; ETANERCEPT; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; INFLIXIMAB; INTERLEUKIN 7 RECEPTOR; METHOTREXATE; PREDNISONE; RHEUMATOID FACTOR; TUMOR NECROSIS FACTOR ALPHA; TUMOR NECROSIS FACTOR ALPHA INHIBITOR;

ADULT; AGED; ARTICLE; BLOOD; COMBINATION CHEMOTHERAPY; DISEASE ACTIVITY; DISEASE ASSOCIATION; DISEASE DURATION; FEMALE; GENE CONTROL; GENE EXPRESSION; HUMAN; LEUKOCYTE; MAJOR CLINICAL STUDY; MALE; MICROARRAY ANALYSIS; PRIORITY JOURNAL; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; RHEUMATOID ARTHRITIS; SCORING SYSTEM; SIGNAL TRANSDUCTION; TREATMENT RESPONSE;

ADULT; AGED; ANTIRHEUMATIC AGENTS; ARTHRITIS, RHEUMATOID; BIOLOGICAL MARKERS; DOWN-REGULATION; FEMALE; GENE EXPRESSION REGULATION; HUMANS; MALE; METHOTREXATE; MIDDLE AGED; NF-KAPPA B P50 SUBUNIT; RECEPTORS, TUMOR NECROSIS FACTOR; SEVERITY OF ILLNESS INDEX; TUMOR NECROSIS FACTOR-ALPHA; UP-REGULATION;

EID: 35948988045     PISSN: 0315162X     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

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