Chromatin compaction and cell death by high molecular weight FGF-2 depend on its nuclear localization, intracrine ERK activation, and engagement of mitochondria

Journal of Cellular Physiology

Volumn 213, Issue 3, 2007, Pages 690-698

  Ma, Xin ^a   Dang, Xitong ^a   Claus, Peter ^b   Hirst, Cheryl ^a   Fandrich, Robert R ^a   Jin, Yan ^a   Grothe, Claudia ^b   Kirshenbaum, Lorrie A ^a   Cattini, Peter A ^a   Kardami, Elissavet ^a,c  

^a UNIVERSITY OF MANITOBA   (Canada)

^b HANNOVER MEDICAL SCHOOL   (Germany)

^c St Boniface Research Centre   (Canada)

Author keywords

[No Author keywords available]

Indexed keywords

2 (2 AMINO 3 METHOXYPHENYL)CHROMONE; CYTOCHROME C; FIBROBLAST GROWTH FACTOR 2; ISOPROTEIN; MITOGEN ACTIVATED PROTEIN KINASE; MITOGEN ACTIVATED PROTEIN KINASE 1; MITOGEN ACTIVATED PROTEIN KINASE 3; PROTEIN BAX; PROTEIN BCL 2;

ARTICLE; CELL DEATH; CHROMATIN COMPACTION; CHROMATIN STRUCTURE; GENE OVEREXPRESSION; HUMAN; HUMAN CELL; INHIBITION KINETICS; MITOCHONDRIAL MEMBRANE; MOLECULAR WEIGHT; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN LOCALIZATION; SEQUENCE ANALYSIS;

ADENOVIRIDAE; ANTIBODIES, MONOCLONAL; CELL DEATH; CELL LINE; CELL NUCLEUS; CHROMATIN; CYTOCHROMES C; CYTOPLASM; ENZYME ACTIVATION; EXTRACELLULAR SIGNAL-REGULATED MAP KINASES; FIBROBLAST GROWTH FACTOR 2; FLAVONOIDS; FLUORESCEIN; FLUORESCENT DYES; HUMANS; IN SITU NICK-END LABELING; KIDNEY; MITOCHONDRIA; MOLECULAR WEIGHT; PLASMIDS; PROTEIN ISOFORMS;

EID: 35848967018     PISSN: 00219541     EISSN: None     Source Type: Journal    
DOI: 10.1002/jcp.21139     Document Type: Article

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