The rational design of β cell cytoprotective gene transfer strategies: Targeting deleterious iNOS expression

Molecular Biotechnology

Volumn 37, Issue 1, 2007, Pages 38-47

  McCabe, Cillian ^a   O'Brien, Timothy ^a  

^a NATIONAL UNIVERSITY OF IRELAND   (Ireland)

Author keywords

Cells; Adenovirus; Antioxidants; Cytokines; Cytoprotection; Gene transfer; IL 1 ; iNOS; Lentivirus; NF B; Rat insulinoma cells; ROS; shRNA

Indexed keywords

ADENOVIRAL VECTORS; ADENOVIRUS; ANTIOXIDANTS; CELL CYTOPROTECTIVES; CYTOKINES; ISLET TRANSPLANTATION; LENTIVIRUS; PLASMID VECTORS; RAT INSULINOMA CELLS;

CELL CULTURE; CELLS; INSULIN; NITROGEN OXIDES; VIRUSES;

GENE TRANSFER;

ADENOVIRUS VECTOR; ANTIOXIDANT; CYTOKINE; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; INDUCIBLE NITRIC OXIDE SYNTHASE; INTERLEUKIN 1BETA; LENTIVIRUS VECTOR; NITRITE; PLASMID VECTOR; GREEN FLUORESCENT PROTEIN; I KAPPA B; NF KAPPAB INHIBITOR ALPHA; NF-KAPPAB INHIBITOR ALPHA; UNCLASSIFIED DRUG;

ACCURACY; ANIMAL CELL; B LYMPHOCYTE; CELL DEATH; CELL PROTECTION; CELL VIABILITY; CONFERENCE PAPER; CONTROLLED STUDY; DRUG INHIBITION; ENZYME ACTIVATION; GENE EXPRESSION; GENE TARGETING; GENE TRANSFER; IN VITRO STUDY; INSULINOMA; NONHUMAN; ADENOVIRUS; ANIMAL; ARTICLE; CELL LINE; DRUG ANTAGONISM; DRUG EFFECT; ENZYMOLOGY; GENE VECTOR; GENETICS; HUMAN; INSULIN DEPENDENT DIABETES MELLITUS; LENTIVIRINAE; PANCREAS ISLET BETA CELL; RAT; TRANSPLANTATION; TUMOR CELL LINE;

ADENOVIRIDAE; LENTIVIRUS; RATTUS;

ADENOVIRIDAE; ANIMALS; CELL LINE; CELL LINE, TUMOR; CYTOPROTECTION; DIABETES MELLITUS, TYPE 1; GENE TRANSFER TECHNIQUES; GENETIC VECTORS; GREEN FLUORESCENT PROTEINS; HUMANS; I-KAPPA B PROTEINS; INSULIN-SECRETING CELLS; INTERLEUKIN-1BETA; LENTIVIRUS; NITRIC OXIDE SYNTHASE TYPE II; RATS;

EID: 35848964770     PISSN: 10736085     EISSN: None     Source Type: Journal    
DOI: 10.1007/s12033-007-0049-6     Document Type: Article

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