-
1
-
-
0041767486
-
Activities of mutant prevention concentration-targeted moxifloxacin and levofloxacin against Streptococcus pneumoniae in an in vitro pharmacodynamic model
-
Allen, G. P., G. W. Kaatz, and M. J. Rybak. 2003. Activities of mutant prevention concentration-targeted moxifloxacin and levofloxacin against Streptococcus pneumoniae in an in vitro pharmacodynamic model. Antimicrob. Agents Chemother. 47:2606-2614.
-
(2003)
Antimicrob. Agents Chemother
, vol.47
, pp. 2606-2614
-
-
Allen, G.P.1
Kaatz, G.W.2
Rybak, M.J.3
-
2
-
-
3342984904
-
In vitro activities of mutant prevention concentration-targeted concentrations of fluoroquinolones against Staphylococcus aureus in a pharmacodynamic model
-
Allen, G. P., G. W. Kaatz, and M. J. Rybak. 2004. In vitro activities of mutant prevention concentration-targeted concentrations of fluoroquinolones against Staphylococcus aureus in a pharmacodynamic model. Int. J. Antimicrob. Agents 24:150-160.
-
(2004)
Int. J. Antimicrob. Agents
, vol.24
, pp. 150-160
-
-
Allen, G.P.1
Kaatz, G.W.2
Rybak, M.J.3
-
3
-
-
0034812780
-
Pharmacodynamics of fluoroquinolones against Streptococcus pneumoniae in patients with community-acquired respiratory tract infections
-
Ambrose, P. G., D. M. Grasela, T. H. Grasela, J. Passarell, H. B. Mayer, and P. F. Pierce. 2001. Pharmacodynamics of fluoroquinolones against Streptococcus pneumoniae in patients with community-acquired respiratory tract infections. Antimicrob. Agents Chemother. 45:2793-2797.
-
(2001)
Antimicrob. Agents Chemother
, vol.45
, pp. 2793-2797
-
-
Ambrose, P.G.1
Grasela, D.M.2
Grasela, T.H.3
Passarell, J.4
Mayer, H.B.5
Pierce, P.F.6
-
4
-
-
11144270151
-
Relationship between increased susceptibility of Streptococcus pneumoniae in the United States
-
Bhavnani, S. M., J. P. Hammel, R. N. Jones, and P. G. Ambrose. 2005. Relationship between increased susceptibility of Streptococcus pneumoniae in the United States. Diagn. Microbiol. Infect. Dis. 51:31-37.
-
(2005)
Diagn. Microbiol. Infect. Dis
, vol.51
, pp. 31-37
-
-
Bhavnani, S.M.1
Hammel, J.P.2
Jones, R.N.3
Ambrose, P.G.4
-
5
-
-
3843150553
-
The role of PK/PD parameters to avoid selection and increase of resistance: Mutant prevention concentration
-
Blondeau, J. M., G. Hansen, K. Metzler, and P. Hedlin. 2004. The role of PK/PD parameters to avoid selection and increase of resistance: mutant prevention concentration. J. Chemother. 14(Suppl. 3):1-19.
-
(2004)
J. Chemother
, vol.14
, Issue.SUPPL. 3
, pp. 1-19
-
-
Blondeau, J.M.1
Hansen, G.2
Metzler, K.3
Hedlin, P.4
-
6
-
-
0035139520
-
Mutant prevention concentrations of fluoroquinolones for clinical isolates of Streptococcus pneumoniae
-
Blondeau, J. M., X. Zhao, G. Hansen, and K. Drlica. 2001. Mutant prevention concentrations of fluoroquinolones for clinical isolates of Streptococcus pneumoniae. Antimicrob. Agents Chemother. 45:433-438.
-
(2001)
Antimicrob. Agents Chemother
, vol.45
, pp. 433-438
-
-
Blondeau, J.M.1
Zhao, X.2
Hansen, G.3
Drlica, K.4
-
8
-
-
35848965865
-
-
Craig, W. A., and D. R. Andes. 2000. Abstr. 40th Intersci, Conf. Antimicrob. Agents Chemother., abstr. A-289.
-
Craig, W. A., and D. R. Andes. 2000. Abstr. 40th Intersci, Conf. Antimicrob. Agents Chemother., abstr. A-289.
-
-
-
-
9
-
-
2142662135
-
Mutant selection window in levofloxacin and moxifloxacin treatments of experimental pneumococcal pneumonia in a rabbit model of human therapy
-
Croisier, D., M. Etienne, E. Bergoin, P. E. Charles, C. Lequeu, L. Piroth, H. Portier, and P. Chavanet. 2004. Mutant selection window in levofloxacin and moxifloxacin treatments of experimental pneumococcal pneumonia in a rabbit model of human therapy. Antimicrob. Agents Chemother. 48:1699-1707.
-
(2004)
Antimicrob. Agents Chemother
, vol.48
, pp. 1699-1707
-
-
Croisier, D.1
Etienne, M.2
Bergoin, E.3
Charles, P.E.4
Lequeu, C.5
Piroth, L.6
Portier, H.7
Chavanet, P.8
-
10
-
-
0037035122
-
Resistance to levofloxacin and failure of treatment of pneumococcal pneumonia
-
Davidson, R., R. Cavalcanti, J. L. Brunton, D. J. Bast, J. C. de Azavedo, P. Kibsey, C. Fleming, and D. E. Low. 2002. Resistance to levofloxacin and failure of treatment of pneumococcal pneumonia. N. Engl. J. Med. 346:747-750.
-
(2002)
N. Engl. J. Med
, vol.346
, pp. 747-750
-
-
Davidson, R.1
Cavalcanti, R.2
Brunton, J.L.3
Bast, D.J.4
de Azavedo, J.C.5
Kibsey, P.6
Fleming, C.7
Low, D.E.8
-
11
-
-
0032803964
-
Effect of fluoroquinolone concentration on selection of resistant mutants of Mycobacterium bovis BCG and Staphylococcus aureus
-
Dong, Y., X. Zhao, J. Domagala, and K. Drlica. 1999. Effect of fluoroquinolone concentration on selection of resistant mutants of Mycobacterium bovis BCG and Staphylococcus aureus. Antimicrob. Agents Chemother. 43:1756-1758.
-
(1999)
Antimicrob. Agents Chemother
, vol.43
, pp. 1756-1758
-
-
Dong, Y.1
Zhao, X.2
Domagala, J.3
Drlica, K.4
-
12
-
-
0011561048
-
The Alexander Project 1996-1997: Latest susceptibility data from this international study of bacterial pathogens from community-acquired lower respiratory tract infections
-
Felmingham, D., and R. N. Gruneberg. 2000. The Alexander Project 1996-1997: latest susceptibility data from this international study of bacterial pathogens from community-acquired lower respiratory tract infections. J. Antimicrob. Chemother. 45:191-203.
-
(2000)
J. Antimicrob. Chemother
, vol.45
, pp. 191-203
-
-
Felmingham, D.1
Gruneberg, R.N.2
-
13
-
-
0036771759
-
AUC/MIC relationships to different endpoints of the antimicrobial effect: Multiple-dose in vitro simulations with moxifloxacin and levofloxacin
-
Firsov, A. A., S. H. Zinner, S. N. Vostrov, Y. A. Portnoy, and I. Y. Lubenko. 2002. AUC/MIC relationships to different endpoints of the antimicrobial effect: multiple-dose in vitro simulations with moxifloxacin and levofloxacin. J. Antimicrob. Chemother. 50:533-539.
-
(2002)
J. Antimicrob. Chemother
, vol.50
, pp. 533-539
-
-
Firsov, A.A.1
Zinner, S.H.2
Vostrov, S.N.3
Portnoy, Y.A.4
Lubenko, I.Y.5
-
14
-
-
0038414586
-
In vitro pharmacodynamic evaluation of the mutant selection window hypothesis using four fluoroquinolones against Staphylococcus aureus
-
Firsov, A. A., S. N. Vostrov, I. Y. Lubenko, K. Drlica, Y. A. Portnoy, and S. H. Zinner. 2003. In vitro pharmacodynamic evaluation of the mutant selection window hypothesis using four fluoroquinolones against Staphylococcus aureus. Antimicrob. Agents Chemother. 47:1604-1613.
-
(2003)
Antimicrob. Agents Chemother
, vol.47
, pp. 1604-1613
-
-
Firsov, A.A.1
Vostrov, S.N.2
Lubenko, I.Y.3
Drlica, K.4
Portnoy, Y.A.5
Zinner, S.H.6
-
15
-
-
1642502330
-
Pharmacodynamics of moxifloxacin and levofloxacin at simulated epithelial lining fluid drug concentrations against Streptococcus pneumoniae
-
Florea, N. R., P. R. Tessier, C. Zhang, C. H. Nightingale, and D. P. Nicolau. 2004. Pharmacodynamics of moxifloxacin and levofloxacin at simulated epithelial lining fluid drug concentrations against Streptococcus pneumoniae. Antimicrob. Agents Chemother. 48:1215-1221.
-
(2004)
Antimicrob. Agents Chemother
, vol.48
, pp. 1215-1221
-
-
Florea, N.R.1
Tessier, P.R.2
Zhang, C.3
Nightingale, C.H.4
Nicolau, D.P.5
-
16
-
-
0027161344
-
Pharmacodynamics of intravenous ciprofloxacin in seriously ill patients
-
Forrest, A., D. E. Nix, C. H. Ballow, T. F. Goss, M. C. Birmingham, and J. J. Schentag. 1993. Pharmacodynamics of intravenous ciprofloxacin in seriously ill patients. Antimicrob. Agents Chemother. 37:1073-1081.
-
(1993)
Antimicrob. Agents Chemother
, vol.37
, pp. 1073-1081
-
-
Forrest, A.1
Nix, D.E.2
Ballow, C.H.3
Goss, T.F.4
Birmingham, M.C.5
Schentag, J.J.6
-
17
-
-
0018096639
-
New in vitro model to study the effect of antibiotic concentration and rate of elimination on antibacterial activity
-
Grasso, S., G. Meinardi, I. de Carneri, and V. Tamassia. 1978. New in vitro model to study the effect of antibiotic concentration and rate of elimination on antibacterial activity. Antimicrob. Agents Chemother. 13:570-576.
-
(1978)
Antimicrob. Agents Chemother
, vol.13
, pp. 570-576
-
-
Grasso, S.1
Meinardi, G.2
de Carneri, I.3
Tamassia, V.4
-
18
-
-
0035189079
-
Increasing resistance of Streptococcus pneumoniae to fluoroquinolones: Results of a Hong Kong multicentre study in 2000
-
Ho, P. L., R. W. Yung, D. N. Tsang, T. L. Que, M. Ho, W. H. Seto, T. K. Ng, W. C. Yam, and W. W. Ng. 2001. Increasing resistance of Streptococcus pneumoniae to fluoroquinolones: results of a Hong Kong multicentre study in 2000. J. Antimicrob. Chemother. 48:659-665.
-
(2001)
J. Antimicrob. Chemother
, vol.48
, pp. 659-665
-
-
Ho, P.L.1
Yung, R.W.2
Tsang, D.N.3
Que, T.L.4
Ho, M.5
Seto, W.H.6
Ng, T.K.7
Yam, W.C.8
Ng, W.W.9
-
19
-
-
0033964495
-
Prevalence of gyrA, gyrB, parC, and parE mutations in clinical isolates of Streptococcus pneumoniae with decreased susceptibilities to different fluoroquinolones and originating from worldwide surveillance studies during the 1997-1998 respiratory season
-
Jones, M. E., D. F. Sahm, N. Martin, S. Scheuring, P. Heisig, C. Thorns berry, K. Kohrer, and F. J. Schmitz. 2000. Prevalence of gyrA, gyrB, parC, and parE mutations in clinical isolates of Streptococcus pneumoniae with decreased susceptibilities to different fluoroquinolones and originating from worldwide surveillance studies during the 1997-1998 respiratory season. Antimicrob. Agents Chemother. 44:462-466.
-
(2000)
Antimicrob. Agents Chemother
, vol.44
, pp. 462-466
-
-
Jones, M.E.1
Sahm, D.F.2
Martin, N.3
Scheuring, S.4
Heisig, P.5
Thorns berry, C.6
Kohrer, K.7
Schmitz, F.J.8
-
20
-
-
0032978288
-
Pharmacodynamic comparisons of levofloxacin, ciprofloxacin, and ampicillin against Streptococcus pneumoniae in an in vitro model of infection
-
Lacy, M. K., W. Lu, X. Xu, P. R. Tessier, D. P. Nicolau, R. Quintiliani, and C. H. Nightingale. 1999. Pharmacodynamic comparisons of levofloxacin, ciprofloxacin, and ampicillin against Streptococcus pneumoniae in an in vitro model of infection. Antimicrob. Agents Chemother. 43:672-677.
-
(1999)
Antimicrob. Agents Chemother
, vol.43
, pp. 672-677
-
-
Lacy, M.K.1
Lu, W.2
Xu, X.3
Tessier, P.R.4
Nicolau, D.P.5
Quintiliani, R.6
Nightingale, C.H.7
-
21
-
-
0036150292
-
Selection of Streptococcus pneumoniae mutants having reduced susceptibility to moxifloxacin and levofloxacin
-
Li, X., X. Zhao, and K. Drlica. 2002. Selection of Streptococcus pneumoniae mutants having reduced susceptibility to moxifloxacin and levofloxacin. Antimicrob. Agents Chemother. 46:522-524.
-
(2002)
Antimicrob. Agents Chemother
, vol.46
, pp. 522-524
-
-
Li, X.1
Zhao, X.2
Drlica, K.3
-
22
-
-
0036136636
-
Pharmacodynamics of gatifloxacin against Streptococcus pneumoniae in an in vitro pharmacokinetic model: Impact of area under the curve/MIC ratios on eradication
-
Lister, P. D. 2002. Pharmacodynamics of gatifloxacin against Streptococcus pneumoniae in an in vitro pharmacokinetic model: impact of area under the curve/MIC ratios on eradication. Antimicrob. Agents Chemother. 46:69-74.
-
(2002)
Antimicrob. Agents Chemother
, vol.46
, pp. 69-74
-
-
Lister, P.D.1
-
23
-
-
0037417014
-
Activities of moxifloxacin against, and emergence of resistance in, Streptococcus pneumoniae and Pseudomonas aeruginosa in an in vitro pharmacokinetic model
-
MacGowan, A. P., C. A. Rogers, H. A. Holt, and K. E. Bowker. 2003. Activities of moxifloxacin against, and emergence of resistance in, Streptococcus pneumoniae and Pseudomonas aeruginosa in an in vitro pharmacokinetic model. Antimicrob. Agents Chemother. 47:1088-1095.
-
(2003)
Antimicrob. Agents Chemother
, vol.47
, pp. 1088-1095
-
-
MacGowan, A.P.1
Rogers, C.A.2
Holt, H.A.3
Bowker, K.E.4
-
24
-
-
0034956119
-
Pharmacodynamic assessment of gatifloxacin against Streptococcus pneumoniae
-
Mattoes, H. M., M. Banevicius, D. Li, C. Turley, D. Xuan, C. H. Nightingale, and D. P. Nicolau. 2001. Pharmacodynamic assessment of gatifloxacin against Streptococcus pneumoniae. Antimicrob. Agents Chemother. 45:2092-2097.
-
(2001)
Antimicrob. Agents Chemother
, vol.45
, pp. 2092-2097
-
-
Mattoes, H.M.1
Banevicius, M.2
Li, D.3
Turley, C.4
Xuan, D.5
Nightingale, C.H.6
Nicolau, D.P.7
-
25
-
-
0032750069
-
Activities of fluoroquinolones against Streptococcus pneumoniae type II topoisomerases purified as recombinant proteins
-
Morrissey, I., and J. George. 1999. Activities of fluoroquinolones against Streptococcus pneumoniae type II topoisomerases purified as recombinant proteins. Antimicrob. Agents Chemother. 43:2579-2585.
-
(1999)
Antimicrob. Agents Chemother
, vol.43
, pp. 2579-2585
-
-
Morrissey, I.1
George, J.2
-
26
-
-
0026693558
-
Phase I study of levofloxacin, (S)-(-)-ofloxacin
-
Nakashima, M., T. Uematsu, M. Kanamaru, O. Okazaki, and H. Hakusai. 1992. Phase I study of levofloxacin, (S)-(-)-ofloxacin. Jpn. J. Clin. Pharmacol. Ther. 23:515-520.
-
(1992)
Jpn. J. Clin. Pharmacol. Ther
, vol.23
, pp. 515-520
-
-
Nakashima, M.1
Uematsu, T.2
Kanamaru, M.3
Okazaki, O.4
Hakusai, H.5
-
27
-
-
32844461168
-
Safety, pharmacokinetics and influence on the intestinal flora of BAY 12-8039 (moxifloxacin hydrochloride) after oral administration in healthy male subjects
-
Ohnishi, A., T. Toyoki, K. Yoshikawa, K. Hashizume, T. Tanigawa, T. Komori, and T. Tanaka. 2005. Safety, pharmacokinetics and influence on the intestinal flora of BAY 12-8039 (moxifloxacin hydrochloride) after oral administration in healthy male subjects. Jpn. Pharmacol. Ther. 33:1029-1045.
-
(2005)
Jpn. Pharmacol. Ther
, vol.33
, pp. 1029-1045
-
-
Ohnishi, A.1
Toyoki, T.2
Yoshikawa, K.3
Hashizume, K.4
Tanigawa, T.5
Komori, T.6
Tanaka, T.7
-
28
-
-
33748701424
-
Selection of ciprofloxacin resistance in Escherichia coli in an in vitro kinetic model: Relation between drug exposure and mutant prevention concentration
-
Olofsson, S. K., L. L. Marcusson, P. K. Lindgren, D. Hughes, and O. Cars. 2006. Selection of ciprofloxacin resistance in Escherichia coli in an in vitro kinetic model: relation between drug exposure and mutant prevention concentration. J. Antimicrob. Chemother. 57:1116-1121.
-
(2006)
J. Antimicrob. Chemother
, vol.57
, pp. 1116-1121
-
-
Olofsson, S.K.1
Marcusson, L.L.2
Lindgren, P.K.3
Hughes, D.4
Cars, O.5
-
29
-
-
8944237982
-
Cloning and characterization of the parC and parE genes of Streptococcus pneumoniae encoding DNA topoisomerase IV: Role in fluoroquinolone resistance
-
Pan, X. S., and L. M. Fisher. 1996. Cloning and characterization of the parC and parE genes of Streptococcus pneumoniae encoding DNA topoisomerase IV: role in fluoroquinolone resistance. J. Bacteriol. 178:4060-4069.
-
(1996)
J. Bacteriol
, vol.178
, pp. 4060-4069
-
-
Pan, X.S.1
Fisher, L.M.2
-
30
-
-
4344588318
-
-
Powis, J., A. McGeer, K. Green, O. Vanderkooi, K. Weiss, G. Zhanel, T. Mazzulli, M. Kuhn, D. Church, R. Davidson, K. Forward, D. Hoban, A. Simor, Canadian Bacterial Surveillance Network, and D. E. Low. 2004. In vitro antimicrobial susceptibilities of Streptococcus pneumoniae clinical isolates obtained in Canada in 2002. Antimicrob. Agents Chemother. 48:3305-3311.
-
Powis, J., A. McGeer, K. Green, O. Vanderkooi, K. Weiss, G. Zhanel, T. Mazzulli, M. Kuhn, D. Church, R. Davidson, K. Forward, D. Hoban, A. Simor, Canadian Bacterial Surveillance Network, and D. E. Low. 2004. In vitro antimicrobial susceptibilities of Streptococcus pneumoniae clinical isolates obtained in Canada in 2002. Antimicrob. Agents Chemother. 48:3305-3311.
-
-
-
-
31
-
-
21444451421
-
Antimicrobial susceptibility of Streptococcus pneumoniae in eight European countries from 2001 to 2003
-
Reinert, R. R., S. Reinert, M. van der Linden, M. Y. Cil, A. Al-Lahham, and P. Appelbaum. 2005. Antimicrobial susceptibility of Streptococcus pneumoniae in eight European countries from 2001 to 2003. Antimicrob. Agents Chemother. 49:2903-2913.
-
(2005)
Antimicrob. Agents Chemother
, vol.49
, pp. 2903-2913
-
-
Reinert, R.R.1
Reinert, S.2
van der Linden, M.3
Cil, M.Y.4
Al-Lahham, A.5
Appelbaum, P.6
-
32
-
-
0027142007
-
Study of an auto-simulation apparatus for evaluating bactericidal activity of antibiotics in human serum
-
Sasaki, S., K. Nishimura, I. Yoshida, T. Munekage, N. Imamura, and M. Ito. 1993. Study of an auto-simulation apparatus for evaluating bactericidal activity of antibiotics in human serum. Jpn. J. Chemother. 41:1056-1063.
-
(1993)
Jpn. J. Chemother
, vol.41
, pp. 1056-1063
-
-
Sasaki, S.1
Nishimura, K.2
Yoshida, I.3
Munekage, T.4
Imamura, N.5
Ito, M.6
-
33
-
-
18644375970
-
Guide to selection of fluoroquinolones in patients with lower respiratory tract infections
-
Shams, W. E., and M. E. Evans. 2005. Guide to selection of fluoroquinolones in patients with lower respiratory tract infections. Drugs 65:949-991.
-
(2005)
Drugs
, vol.65
, pp. 949-991
-
-
Shams, W.E.1
Evans, M.E.2
-
34
-
-
0029911379
-
Contribution of mutations in gyrA and parC genes to fluoroquinolone resistance of mutants of Streptococcus pneumoniae obtained in vivo and in vitro
-
Tankovic, J., B. Perichon, J. Duval, and P. Courvalin. 1996. Contribution of mutations in gyrA and parC genes to fluoroquinolone resistance of mutants of Streptococcus pneumoniae obtained in vivo and in vitro. Antimicrob. Agents Chemother. 40:2505-2510.
-
(1996)
Antimicrob. Agents Chemother
, vol.40
, pp. 2505-2510
-
-
Tankovic, J.1
Perichon, B.2
Duval, J.3
Courvalin, P.4
-
35
-
-
0033057693
-
ParC and GyrA may be interchangeable initial targets of some fluoroquinolones in Streptococcus pneumoniae
-
Varon, E., C. Janoir, M. D. Kitzis, and L. Gutmann. 1999. ParC and GyrA may be interchangeable initial targets of some fluoroquinolones in Streptococcus pneumoniae. Antimicrob. Agents Chemother. 43:302-306.
-
(1999)
Antimicrob. Agents Chemother
, vol.43
, pp. 302-306
-
-
Varon, E.1
Janoir, C.2
Kitzis, M.D.3
Gutmann, L.4
-
36
-
-
20144369732
-
In vitro susceptibilites to levofloxacin and various antibacterial agents of 11,475 clinical isolates obtained from 52 centers in 2002
-
Yamaguchi, K., A. Ohno, F. Kashitani, and M. Iwata. 2005. In vitro susceptibilites to levofloxacin and various antibacterial agents of 11,475 clinical isolates obtained from 52 centers in 2002. Jpn. J. Antibiot. 58:17-44.
-
(2005)
Jpn. J. Antibiot
, vol.58
, pp. 17-44
-
-
Yamaguchi, K.1
Ohno, A.2
Kashitani, F.3
Iwata, M.4
-
37
-
-
0036178134
-
A critical review of the fluoroquinolones
-
Zhanel, G. G., K. Ennis, L. Vercaigne, A. Walkty, A. S. Gin, J. Embil, H. Smith, and D. J. Hoban. 2002. A critical review of the fluoroquinolones. Drugs 62:13-59.
-
(2002)
Drugs
, vol.62
, pp. 13-59
-
-
Zhanel, G.G.1
Ennis, K.2
Vercaigne, L.3
Walkty, A.4
Gin, A.S.5
Embil, J.6
Smith, H.7
Hoban, D.J.8
-
38
-
-
0141894015
-
Emergence of resistant Streptococcus pneumoniae in an in vitro dynamic model that simulates moxifloxacin concentrations inside and outside the mutant selection window: Related changes in susceptibility, resistance frequency and bacterial killing
-
Zinner, S. H., I. Y. Lubenko, D. Gilbert, K. Simmons, X. Zhao, K. Drlica, and A. A. Firsov. 2003. Emergence of resistant Streptococcus pneumoniae in an in vitro dynamic model that simulates moxifloxacin concentrations inside and outside the mutant selection window: related changes in susceptibility, resistance frequency and bacterial killing. J. Antimicrob. Chemother. 52:616-622.
-
(2003)
J. Antimicrob. Chemother
, vol.52
, pp. 616-622
-
-
Zinner, S.H.1
Lubenko, I.Y.2
Gilbert, D.3
Simmons, K.4
Zhao, X.5
Drlica, K.6
Firsov, A.A.7
|