Could vitamin D be the answer to multiple sclerosis?

Multiple Sclerosis

Volumn 13, Issue 7, 2007, Pages 825-826

  Broadley, Simon A ^a  

^a GRIFFITH UNIVERSITY   (Australia)

Author keywords

[No Author keywords available]

Indexed keywords

VITAMIN D;

AUTOIMMUNITY; CHROMOSOME 6; EDITORIAL; ENVIRONMENTAL FACTOR; GENETIC ASSOCIATION; GENETIC LINKAGE; GENETIC SUSCEPTIBILITY; GEOGRAPHIC DISTRIBUTION; HUMAN; IMMUNE RESPONSE; MULTIPLE SCLEROSIS; NONHUMAN; POPULATION MIGRATION; PREVALENCE; RISK ASSESSMENT; RISK FACTOR; VITAMIN D DEFICIENCY; VITAMIN SUPPLEMENTATION; IMMUNOLOGY;

HUMANS; MULTIPLE SCLEROSIS; RISK FACTORS; VITAMIN D; VITAMIN D DEFICIENCY;

EID: 35848946351     PISSN: 13524585     EISSN: None     Source Type: Journal    
DOI: 10.1177/1352458507078683     Document Type: Editorial

References (20)

1. Lucchinetti C, Bruck W, Parisi J, Scheithauer B, Rodriguez M, Lassmann H. Heterogeneity of multiple sclerosis lesions: implications for the pathogenesis of demyelination. Ann Neurol 2000; 47: 707-17.
2. Barnett MH, Prineas JW. Relapsing and remitting multiple sclerosis: pathology of the newly forming lesion. Ann Neurol 2004; 55: 458-68.
3. Coles AJ, Wing M, Smith S, Coraddu F, Greer S, Taylor C et al. Pulsed monoclonal antibody treatment and autoimmune thyroid disease in multiple sclerosis. Lancet 1999; 354: 1691-95.
4. Ebers GC, Bulman DE, Sadovnick AD, Paty DW, Warren S, Hader W et al. A population-based study of multiple sclerosis in twins. N Engl J Med 1986; 315: 1638-42.
5. Sawcer S, Ban M, Maranian M, Yeo TW, Compston A, Kirby A et al. A high-density screen for linkage in multiple sclerosis. Am J Hum Genet 2005; 77: 454-67.
6. Hammond SR, English DR, McLeod JG. The age-range of risk of developing multiple sclerosis: evidence from a migrant population in Australia. Brain 2000; 123: 968-74.
7. Compston A. Genetic epidemiology of multiple sclerosis. J Neurol Neurosurg Psychiatry 1997; 62: 553-61.
8. McLeod JG, Hammond SR, Hallpike JF. Epidemiology of multiple sclerosis in Australia. With NSW and SA survey results. Med J Aust 1994; 160: 117-22.
9. Goldacre MJ, Abisgold JD, Yeates DG, Seagroatt V Risk of multiple sclerosis after head injury: record linkage study. J Neurol Neurosurg Psychiatry 2006; 77: 351-53.
10. Bangsi D, Ghadirian P, Ducic S, Morisset R, Ciccocioppo S, McMullen E et al. Dental amalgam and multiple sclerosis: a case-control study in Montreal, Canada. Int J Epidemiol 1998; 27: 667-71.
11. Zorzon M, Zivadinov R, Nasuelli D, Dolfini P, Bosco A, Bratina A et al. Risk factors of multiple sclerosis: a case-control study. Neurol Sci 2003; 24: 242-47.
12. Riise T, Nortvedt MW, Ascherio A. Smoking is a risk factor for multiple sclerosis. Neurology 2003; 61: 1122-24.
13. Ascherio A, Munger KL, Lennette ET, Spiegelman D, Hernan MA, Olek MJ et al. Epstein-Barr virus antibodies and risk of multiple sclerosis: a prospective study. JAMA 2001; 286: 3083-88.
14. Munger KL, Zhang SM, O'Reilly E, Hernan MA, Olek MJ, Willett WC et al. Vitamin D intake and incidence of multiple sclerosis. Neurology 2004; 62: 60-65.
15. Yang S, Smith C, Prahl JM, Luo X, DeLuca HF. Vitamin D deficiency suppresses cell-mediated immunity in vivo. Arch Biochem Biophys 1993; 303: 98-106.
16. Eyles D, Almeras L, Benech P, Patatian A, Mackay-Sim A, McGrath J et al. Developmental vitamin D deficiency alters the expression of genes encoding mitochondrial, cytoskeletal and synaptic proteins in the adult rat brain. J Steroid Biochem Mol Biol 2007; 103: 538-45.
17. Ponsonby AL, Lucas RM, van der Mei IA. UVR, vitamin D and three autoimmune diseases - multiple sclerosis, type 1 diabetes, rheumatoid arthritis. Photochem Photobiol 2005; 81: 1267-75.
18. van der Mei IA, Ponsonby AL, Dwyer T, Blizzard L, Simmons R, Taylor BV et al. Past exposure to sun, skin phenotype, and risk of multiple sclerosis: case-control study. Br Med 12003; 327: 316.
19. Lucas RM, Ponsonby AL, McMichael AJ, van der Mei IA, Chapman C, Coulthard A et al. Observational analytical studies in multiple sclerosis: controlling bias through study design and conduct. The Australian Multicentre study of Environment and Immune Function. Mult Scler 2007; 13: 827-39.
20. Chaudhuri A. Why we should offer routine vitamin D supplementation in pregnancy and childhood to prevent multiple sclerosis. Med Hypotheses 2005; 64: 608-18.