Genetic epidemiology of multiple sclerosis

Journal of Neurology Neurosurgery and Psychiatry

Volumn 62, Issue 6, 1997, Pages 553-561

  Compston, Alastair ^a,b  

^a UNIVERSITY OF CAMBRIDGE   (United Kingdom)

^b UNIVERSITY OF CAMBRIDGE   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

DISEASE COURSE; ENVIRONMENTAL FACTOR; FAROE ISLANDS; GENETIC EPIDEMIOLOGY; GENETIC SUSCEPTIBILITY; HUMAN; MIGRATION; MULTIPLE SCLEROSIS; PRIORITY JOURNAL; REVIEW; RISK FACTOR; SCANDINAVIA;

EID: 0031011567     PISSN: 00223050     EISSN: None     Source Type: Journal    
DOI: 10.1136/jnnp.62.6.553     Document Type: Review

References (79)

1. Poser CM, Benedikz J, Hibberd PL. The epidemiology of multiple sclerosis: the Iceland model. Onset-adjusted prevalence rate and other methodological considerations. J Neurol Sci 1992;111:143-52.
2. Kurtzke JF. A reassessment of the distribution of multiple sclerosis. Part one. Acta Neurol Scand 1975;51:110-36.
3. Kurtzke JF, A reassessment of the distribution of multiple sclerosis. Part two. Acta Neurol Scand 1975;51:137-57.
4. Kurtzke JF. Geography in multiple sclerosis. J Neurol 1977;215:1-26.
5. Bauer HJ. Multiple sclerosis in Europe. Symposium report. J Neurol 1987;234:195-206.
6. Lauer K, Firnhaber W. Multiple sclerosis in Europe: an epidemiological update. Darmstadt: Leuchturm-Verlag/LTV Press, 1994:350.
7. Kurtzke JF. Epidemiologic evidence for multiple sclerosis as an infection. Clin Microbiol Rev 1993;6:382-427.
8. Robertson NP, Compston DAS. Surveying multiple sclerosis in the United Kingdom. J Neurol Neurosurg Psychiatry 1995;58:2-6.
9. Rosati G. Descriptive epidemiology of multiple sclerosis in Europe in the 1980s: a critical overview. Ann Neurol 1994;36(suppl2):S164-74.
10. Bulman D, Ebers GC. The geography of multiple sclerosis reflects genetic susceptibility. Journal of Tropical and Geographical Neurology 1992;2:66-72.
11. Hammond SR, McLeod JG, Millingen KS, Stewart-Wynne EG, English D, Holland JT, McCall MG. The epidemiology of multiple sclerosis in 3 Australian cities: Perth, Newcastle, and Hobart. Brain 1988;111:1-25.
12. Dean G. Annual incidence, prevalence, and mortality of MS in white South African-born and in white immigrants to South Africa. BMJ 1967;ii:724-30.
13. Elian M, Dean G. Multiple sclerosis among United Kingdom born children of immigrants from the West Indies. J Neurol Neurosurg Psychiatry 1987;50:327-32.
14. Elian M, Nightingale S, Dean G. Multiple sclerosis among United Kingdom-born children of immigrants from the Indian subcontinent, Africa, and the West Indies. J Neurol Neurosurg Psychiatry 1990;53:906-11.
15. Kurtzke JF, Bui QH. Multiple sclerosis in a migrant population to half orientals immigrating in childhood. Ann Neurol 1980;8:256-60.
16. Alter M, Okihiro M, Rowley W, Morris T. Multiple sclerosis among orientals and caucasians in Hawaii. Neurology 1971;21:122-30.
17. Lauer K. The risk of multiple sclerosis in the USA in relation to sociogeographic features: a factor-analytic study. J Clin Epidemiol 1994;47:43-8.
18. Detels R, Brody JF, Edgar AH. Multiple sclerosis among American, Japanese, and Chinese migrants to California and Washington. J Chron Dis 1972;25:3-10.
19. Detels R, Visscher B, Malmgrem RM, Coulson AH, Lucia MV, Dudley JP. Evidence for lower susceptibility to multiple sclerosis in Japanese-Americans. Am J Epidemiol 1977;105:303-10.
20. Kuroiwa Y, Shibasaki H, Ikeda M. Prevalence of multiple sclerosis and its north-south gradient in Japan. Neuroepidemiology 1983;2:62-9.
21. Alter M, Halpern L, Kurland LT, Bornstein V, Tikva P, Leibowitz U, Silberstein J. Multiple sclerosis in Israel: prevalence among immigrants and native inhabitants. Arch Neurol 1962;7:253-63.
22. Alter M, Kahana E, Loewenson R. Migration and risk of multiple sclerosis. Neurology 1978;28:1089-93.
23. Kahana E, Zilber N, Abramson JH, Biton Y, Leibowitz Y, Abramsky O. Multiple sclerosis: genetic versus environmental aetiology: epidemiology in Israel updated. J Neurol 1994;241:341-6.
24. Kurtzke JF, Kurland LT, Goldberg ID. Mortality and migration in multiple sclerosis. Neurology 1971;21: 1186-97.
25. Delasnerie-Laupretre N, Alperovitch A. Migration and age at onset of multiple sclerosis in the pitfalls of migrant studies. Acta Neurol Scand 1992;85:408-11.
26. Kurtzke JF, Gudmundsson KR, Bergmann S. Multiple sclerosis in Iceland. 1. Evidence of a post-war epidemic. Neurology 1982;32:143-50.
27. Cook SD, Gudmundsson G, Benedikz J, Dowling PC. Multiple sclerosis and distemper in Iceland. 1966-78. Acta Neurol Scand 1980;61:244-51.
28. Benedikz JG, Magnusson H, Poser CM, Benedikz E, Olafsdottir G, Gudmundsson G. Multiple sclerosis in Iceland 1900-85. Journal of Tropical Geographical Neurology 1991;1:16-22.
29. Benedikz JG, Magnusson H, Gudmundsson G. Multiple sclerosis in Iceland, with observations on the alleged epidemic in the Faroe Islands. Ann Neurol 1994;36(suppl 2):S175-9.
30. Allison RS. Some neurologic aspects of medical geography. Proc R Soc Med 1963;56:71-6.
31. Fog T, Hyllested K. Prevalence of disseminated sclerosis in the Faroes, the Orkneys, and Shetland. Acta Neurol Scand 1966;42(suppl 19):9-11.
32. Kurtzke JF, Hyllested K. Multiple sclerosis in the Faroe Islands: 1. Clinical and epidemiological features. Ann Neurol 1979;5:6-21.
33. Kurtzke KF, Hyllested K. Multiple sclerosis in the Faroe Islands. II. Clinical update, transmission, and the nature of MS. Neurology 1986;36:307-28.
34. Kurtzke JF, Hyllested K. Multiple sclerosis in the Faroe Islands. III. An alternative assessment of the three epidemics. Acta Neurol Scand 1987;76:317.
35. Kurtzke JF, Hyllested K. Validity of the epidemics of multiple sclerosis in the Faroe islands. Neuroepidemiology 1988;7:190-227.
36. Poser CM, Hibberd PL, Benedicz J, Gudmundsson G. Analysis of the "epidemic" of multiple sclerosis in the Faroe Islands. I. Clinical and epidemiological aspects. Neuroepidemiology 1988;7:168-80.
37. Poser CM, Hibberd PL. Analysis of the "epidemic" of multiple sclerosis in the Faroe Islands. II. Biostatistical aspects. Neuroepidemiology 1988;7:181-9.
38. Cook SD, Cromarty MB, Tapp W, Poskanzer D, Walker JD, Dowling PC. Declining incidence of multiple sclerosis in the Orkney Islands. Neurology 1985;35:545-51.
39. Sheremata WA, Poskanzer DC, Withum DG, MacLeod CL, Whiteside ME. Unusual occurrence on a tropical island of multiple sclerosis [letter]. Lancet 1985;ii:618.
40. Weinshenker BG, Bass B, Rice GP, Noseworthy J, Carriere W, Baskerville J, Ebers GC. The natural history of multiple sclerosis: a geographicaly based study. 2. Predictive value of the early clinical course. Brain 1989;112: 1419-28.
41. Weinshenker BG, Bass B, Rice GP, Noseworthy J, Carriere W, Baskerville J, Ebers GC. The natural history of multiple sclerosis: a geographically based study. 3. Multivariate analysis of predictive factors and models of outcome. Brain 1991;114:1045-56.
42. Duquette P, Murray TJ, Pleines J, Ebers GC, Sadovnick D, Weldon P, et al. Multiple sclerosis in childhood: clinical profile in 125 patients. J Pediatr 1987;3:359-63.
43. Runmarker B, Andersen O. Prognostic factors in a multiple sclerosis incident cohort with 25 years of follow up. Brain 1993;116:117-34.
44. Sibley WA, Bamford CR, Clark K, Smith MS, Laguna JF. A prospective study of physical trauma and multiple sclerosis. J Neurol Neurosurg Psychiatry 1991;54:584-9.
45. Siva A, Radhakrishnan K, Kurland LT, O'Brien PC, Swanson JW, Rodriguez M. Trauma and multiple sclerosis: a population based cohort study from Olmsted County, Minnesota. Neurology 1993;43:1878-82.
46. Baskett PJF, Armstrong R. Anaesthetic problems in multiple sclerosis. Anaesthesia 1970;25:397-401.
47. Siemkowicz E. Multiple sclerosis and surgery. Anaesthesia 1976;31:1211-6.
48. Sibley, WA, Bamford CR, Clark K. Clinical viral infections and multiple sclerosis. Lancet 1985;i:1313-5.
49. Andersen O, Lygner P-E, Berstrom T, Andersson M, Vahlne A. Viral infections trigger multiple sclerosis relapses: a prospective seroepidemiological study. J Neurol 1991;240:417-22.
50. Birk K, Ford C, Smeltzer S, Ryan D, Miller R, Rudick RA. The clinical course of multiple sclerosis during pregnancy and the puerperium. Arch Neurol 1990;47:738-42.
51. Rouillet E, Verdier-Taillefer M-H, Amarenco P, Gharbi G, Alperovitch A, Marteau R. Pregnancy and multiple sclerosis: a longitudinal study of 125 remittent patients. J Neurol Nurosurg Psychiatry 1993;56:1062-5.
52. Worthington J, Jones R, Crawford M, Forti A. Pregnancy and multiple sclerosis - a 3 year prospective study. J Neurol 1994;241:228-33.
53. Korn-Lubetzki I, Kahana E, Cooper G, Abramasky O. Activity of multiple sclerosis during pregnancy and puerperium. Ann Neurol 1984;16:228-31.
54. Frith JA, McLeod JG. Pregnancy and multiple sclerosis. J Neurol Neurosurg Psychiatry 1988;51:495-8.
55. Bemardi S, Grasso MG, Bertollini R, Orzi F, Fieschi C. The influence of pregnancy on relapses in multiple sclerosis: a cohort study. Acta Neurol Scand 1991;84:403-6.
56. Runmarker B, Andersen O. Pregnancy is associated with a lower risk of onset and a better prognosis in multiple sclerosis. Brain 1995;118:253-61.
57. Sadovnick AD, Baird PA, Ward RH. Multiple sclerosis; updated risks for relatives. Am J Med Genet 1988;29: 533-41.
58. Robertson NP, Fraser M, Deans J, Clayton D, Compston DAS. Age adjusted recurrence risks for relatives of patients with multiple sclerosis. Brain 1996;119:449-55.
59. Carton H, Vlietinck R, Debruyne J, De Keyser J, D'Hooghe M-B, Loos R, et al. Recurrence risks of multiple sclerosis in relatives of patients in Flanders, Belgium. J Neurol Neurosurg Psychiatry 1997;62:329-33.
60. Ebers GC, Bulman DE, Sadovnick AD, Paly DW, Warren S, Hader W, et al. A population based study of multiple sclerosis in twins. N Engl J Med 1986;315:1638-42.
61. Sadovnick AD, Armstrong H, Rice GPA, Bulman D, Hashimoto L, Paty DW, et al. A population-based study of multiple sclerosis in twins: update. Ann Neurol 1993; 33:281-5.
62. French Research Group on Multiple Sclerosis. Multiple sclerosis in 54 twinships: concordance rate is independent of zygosity. Ann Neurol 1992;32:724-7.
63. Mumford CJ, NW Wood, HF Kellar-Wood, J Thorpe, Miller D, Compston DAS. The British Isles survey of multiple sclerosis in twins. Neurology 1994;44:11-5.
64. Ebers GC, Sadovnick AD, Risch NJ. A genetic basis for familial aggregation in multiple sclerosis. Nature 1995; 377:150-1.
65. Sadovnick AD, Ebers GC, Dyment DA, Risch N, the Canadian Collaborative Study Group. Evidence for genetic basis of multiple sclerosis. Lancet 1996;347: 1728-30.
66. Robertson NP, Clayton D, Fraser MB, Deans J, Compston DAS. Conjugal multiple sclerosis. Lancet 1997 (in press).
67. Olerup O, Hillert J. HLA class II-associated genetic susceptibility in multiple sclerosis: a critical evaluation. Tissue Antigens 1991;38:1-15.
68. Seboun E, Robinson MA, Doolittle TH, Ciulla TA, Kindt TJ, Hauser SL. A susceptibility locus for multiple sclerosis is linked to the T cell receptor β chain complex. Cell 1989;57:1095-100.
69. Wood NW, Kellar-Wood HF, Holmans P, Clayton D, Robertson N, Compston DAS. The T-cell receptor β locus and susceptibility to multiple sclerosis. Neurology 1995;45:1859-63.
70. Walter MA, Gibson WT, Ebers GC, Cox DW. Susceptibility to multiple sclerosis is associated with the proximal immunoglobulin heavy chain region. J Clin Invest 1991;87:1266-73.
71. Wood N, Sawcer SJ, Kellar-Wood H, Holmans P, Clayton D, Robertson N, Compston DAS. A susceptibility gene for multiple sclerosis linked to the immunoglobulin heavy chain variable region. J Neurol 1995;242:677-82.
72. Sawcer S, Jones HB, Feakes R, Gray J, Smaldon N, Chataway J, et al. A genome screen in multiple sclerosis reveals susceptibility loci on chromosome 6p21 and 17q22. Nat Genet 1996;13:464-8.
73. Ebers GC, Kukay K, Bulman D, Sadovnick AD, Rice G, Anderson C, et al. A full genome search in multiple sclerosis. Nat Genet 1996;13:472-6.
74. The Multiple Sclerosis Genetics Group. A complete genomic screen for multiple sclerosis underscores a role for the major histocompatibility complex. Nat Genet 1996;13:469-71.
75. Davenport CB. Multiple sclerosis from the standpoint of geographic distribution and race. Arch Neurol 1922;8: 51-8.
76. Sutherland JM. Observations on the prevalence of multiple sclerosis in northern Scotland. Brain 1956;79:635-54.
77. Chakraborty R, Kamboh, MI, Nwankwo M, Ferrell RE. Caucasian genes in American blacks: new data. Am J Hum Genet 1992;50:145-55.
78. Cavalli-Sforza LL, Menozzi P, Piazza A. The history and geography of human genes. Princeton: Princeton Universty Press, 1994:541.
79. Poser CM. The dissemination of multiple sclerosis: a Viking saga? A historical essay. Ann Neurol 1994;36(suppl 2):S231-43.