-
2
-
-
23344453013
-
Genetics of Parkinson's disease
-
Gasser T. Genetics of Parkinson's disease. Curr Opin Neurol 2005;18:363-369.
-
(2005)
Curr Opin Neurol
, vol.18
, pp. 363-369
-
-
Gasser, T.1
-
3
-
-
28544441389
-
Genetics of Parkinson's disease: LRRK2 on the rise
-
Brice A. Genetics of Parkinson's disease: LRRK2 on the rise. Brain 2005;128:2760-2762.
-
(2005)
Brain
, vol.128
, pp. 2760-2762
-
-
Brice, A.1
-
4
-
-
8844233579
-
Mutations in LRRK2 cause autosomal-dominant parkinsonism with pleomorphic pathology
-
Zimprich A, Biskup S, Leitner P, et al. Mutations in LRRK2 cause autosomal-dominant parkinsonism with pleomorphic pathology. Neuron 2004;44:601-607.
-
(2004)
Neuron
, vol.44
, pp. 601-607
-
-
Zimprich, A.1
Biskup, S.2
Leitner, P.3
-
5
-
-
8844266996
-
Cloning of the gene containing mutations that cause PARK8-linked Parkinson's disease
-
Paisan-Ruiz C, Jain S, Evans EW, et al. Cloning of the gene containing mutations that cause PARK8-linked Parkinson's disease. Neuron 2004;44:595-600.
-
(2004)
Neuron
, vol.44
, pp. 595-600
-
-
Paisan-Ruiz, C.1
Jain, S.2
Evans, E.W.3
-
6
-
-
0345118282
-
-
Bosgraaf L, Van Haastert PJ. Roc, a Ras/GTPase domain in complex proteins. Biochim Biophys Acta 2003;1643:5-10.
-
Bosgraaf L, Van Haastert PJ. Roc, a Ras/GTPase domain in complex proteins. Biochim Biophys Acta 2003;1643:5-10.
-
-
-
-
7
-
-
29444437871
-
Leucine-rich repeat kinase 2 (LRRK2) interacts with parkin, and mutant LRRK2 induces neuronal degeneration
-
Smith WW, Pei Z, Jiang H, et al. Leucine-rich repeat kinase 2 (LRRK2) interacts with parkin, and mutant LRRK2 induces neuronal degeneration. Proc Natl Acad Sci USA 2005;102:18676-18681.
-
(2005)
Proc Natl Acad Sci USA
, vol.102
, pp. 18676-18681
-
-
Smith, W.W.1
Pei, Z.2
Jiang, H.3
-
8
-
-
20044394901
-
Clinical and positron emission tomography of Parkinson's disease caused by LRRK2
-
Hernandez DG, Paisan-Ruiz C, McInerney-Leo A, et al. Clinical and positron emission tomography of Parkinson's disease caused by LRRK2. Ann Neurol 2005;57:453-456.
-
(2005)
Ann Neurol
, vol.57
, pp. 453-456
-
-
Hernandez, D.G.1
Paisan-Ruiz, C.2
McInerney-Leo, A.3
-
9
-
-
19944432606
-
Genetic screening for a single common LRRK2 mutation in familial Parkinson's disease
-
Nichols WC, Pankratz N, Hernandez D, et al. Genetic screening for a single common LRRK2 mutation in familial Parkinson's disease. Lancet 2005;365:410-412.
-
(2005)
Lancet
, vol.365
, pp. 410-412
-
-
Nichols, W.C.1
Pankratz, N.2
Hernandez, D.3
-
10
-
-
19944431081
-
A frequent LRRK2 gene mutation associated with autosomal dominant Parkinson's disease
-
Di Fonzo A, Rohe CF, Ferreira J, et al. A frequent LRRK2 gene mutation associated with autosomal dominant Parkinson's disease. Lancet 2005;365:412-415.
-
(2005)
Lancet
, vol.365
, pp. 412-415
-
-
Di Fonzo, A.1
Rohe, C.F.2
Ferreira, J.3
-
11
-
-
19944432921
-
A common LRRK2 mutation in idiopathic Parkinson's disease
-
Gilks WP, Abou-Sleiman PM, Gandhi S, et al. A common LRRK2 mutation in idiopathic Parkinson's disease. Lancet 2005;365:415-416.
-
(2005)
Lancet
, vol.365
, pp. 415-416
-
-
Gilks, W.P.1
Abou-Sleiman, P.M.2
Gandhi, S.3
-
12
-
-
20144387207
-
Identification of a novel LRRK2 mutation linked to autosomal dominant parkinsonism: Evidence of a common founder across European populations
-
Kachergus J, Mata IF, Hulihan M, et al. Identification of a novel LRRK2 mutation linked to autosomal dominant parkinsonism: evidence of a common founder across European populations. Am J Hum Genet 2005;76:672-680.
-
(2005)
Am J Hum Genet
, vol.76
, pp. 672-680
-
-
Kachergus, J.1
Mata, I.F.2
Hulihan, M.3
-
13
-
-
18244394793
-
Clinical features of LRRK2-associated Parkinson's disease in central Norway
-
Aasly JO, Toft M, Fernandez-Mata I, et al. Clinical features of LRRK2-associated Parkinson's disease in central Norway. Ann Neurol 2005;57:762-765.
-
(2005)
Ann Neurol
, vol.57
, pp. 762-765
-
-
Aasly, J.O.1
Toft, M.2
Fernandez-Mata, I.3
-
14
-
-
33644929033
-
LRRK2 mutations in Spanish patients with Parkinson disease: Frequency, clinical features, and incomplete penetrance
-
Gaig C, Ezquerra M, Marti MJ, Munoz E, Valldeoriola F, Tolosa E. LRRK2 mutations in Spanish patients with Parkinson disease: frequency, clinical features, and incomplete penetrance. Arch Neurol 2006;63:377-382.
-
(2006)
Arch Neurol
, vol.63
, pp. 377-382
-
-
Gaig, C.1
Ezquerra, M.2
Marti, M.J.3
Munoz, E.4
Valldeoriola, F.5
Tolosa, E.6
-
15
-
-
22544465257
-
LRRK2 haplotype analyses in European and North African families with Parkinson disease: A common founder for the G2019S mutation dating from the 13th century
-
Lesage S, Leutenegger AL, Ibanez P, et al. LRRK2 haplotype analyses in European and North African families with Parkinson disease: a common founder for the G2019S mutation dating from the 13th century. Am J Hum Genet 2005;77:330-332.
-
(2005)
Am J Hum Genet
, vol.77
, pp. 330-332
-
-
Lesage, S.1
Leutenegger, A.L.2
Ibanez, P.3
-
16
-
-
33645160640
-
The G6055A (G2019S) mutation in LRRK2 is frequent in both early and late onset Parkinson's disease and originates from a common ancestor
-
Goldwurm S, Di Fonzo A, Simons EJ, et al. The G6055A (G2019S) mutation in LRRK2 is frequent in both early and late onset Parkinson's disease and originates from a common ancestor. J Med Genet 2005;42:e65.
-
(2005)
J Med Genet
, vol.42
-
-
Goldwurm, S.1
Di Fonzo, A.2
Simons, E.J.3
-
17
-
-
33749021352
-
LRRK2 G2019S in families with Parkinson disease who originated from Europe and the Middle East: Evidence of two distinct founding events beginning two millennia ago
-
Zabetian CP, Hutter CM, Yearout D, et al. LRRK2 G2019S in families with Parkinson disease who originated from Europe and the Middle East: evidence of two distinct founding events beginning two millennia ago. Am J Hum Genet 2006;79:752-758.
-
(2006)
Am J Hum Genet
, vol.79
, pp. 752-758
-
-
Zabetian, C.P.1
Hutter, C.M.2
Yearout, D.3
-
18
-
-
27644455523
-
G2019S LRRK2 mutation in French and North African families with Parkinson's disease
-
Lesage S, Ibanez P, Lohmann E, et al. G2019S LRRK2 mutation in French and North African families with Parkinson's disease. Ann Neurol 2005;58:784-787.
-
(2005)
Ann Neurol
, vol.58
, pp. 784-787
-
-
Lesage, S.1
Ibanez, P.2
Lohmann, E.3
-
19
-
-
31344432937
-
LRRK2 G2019S as a cause of Parkinson's disease in North African Arabs
-
Lesage S, Durr A, Tazir M, et al. LRRK2 G2019S as a cause of Parkinson's disease in North African Arabs. N Engl J Med 2006;354:422-423.
-
(2006)
N Engl J Med
, vol.354
, pp. 422-423
-
-
Lesage, S.1
Durr, A.2
Tazir, M.3
-
20
-
-
31344439221
-
LRRK2 G2019S as a cause of Parkinson's disease in Ashkenazi Jews
-
Ozelius LJ, Senthil G, Saunders-Pullman R, et al. LRRK2 G2019S as a cause of Parkinson's disease in Ashkenazi Jews. N Engl J Med 2006;354:424-425.
-
(2006)
N Engl J Med
, vol.354
, pp. 424-425
-
-
Ozelius, L.J.1
Senthil, G.2
Saunders-Pullman, R.3
-
21
-
-
33845453622
-
Frequency of LRRK2 mutations in early- and late-onset Parkinson disease
-
Clark LN, Wang Y, Karlins E, et al. Frequency of LRRK2 mutations in early- and late-onset Parkinson disease. Neurology 2006;67:1786-1791.
-
(2006)
Neurology
, vol.67
, pp. 1786-1791
-
-
Clark, L.N.1
Wang, Y.2
Karlins, E.3
-
22
-
-
0026514953
-
Accuracy of clinical diagnosis of idiopathic Parkinson's disease: A clinico-pathological study of 100 cases
-
Hughes AJ, Daniel SE, Kilford L, Lees AJ. Accuracy of clinical diagnosis of idiopathic Parkinson's disease: a clinico-pathological study of 100 cases. J Neurol Neurosurg Psychiatry 1992;55:181-184.
-
(1992)
J Neurol Neurosurg Psychiatry
, vol.55
, pp. 181-184
-
-
Hughes, A.J.1
Daniel, S.E.2
Kilford, L.3
Lees, A.J.4
-
23
-
-
33645524312
-
RNA-SEL mutation screening and association study in Ashkenazi and non-Ashkenazi prostate cancer patients
-
Orr-Urtreger A, Bar-Shira A, Bercovich D, et al. RNA-SEL mutation screening and association study in Ashkenazi and non-Ashkenazi prostate cancer patients. Cancer Epidemiol Biomarkers Prev 2006;15:474-479.
-
(2006)
Cancer Epidemiol Biomarkers Prev
, vol.15
, pp. 474-479
-
-
Orr-Urtreger, A.1
Bar-Shira, A.2
Bercovich, D.3
-
24
-
-
28344457936
-
Lrrk2 pathogenic substitutions in Parkinson's disease
-
Mata IF, Kachergus JM, Taylor JP, et al. Lrrk2 pathogenic substitutions in Parkinson's disease. Neurogenetics 2005;6:171-177.
-
(2005)
Neurogenetics
, vol.6
, pp. 171-177
-
-
Mata, I.F.1
Kachergus, J.M.2
Taylor, J.P.3
-
25
-
-
0038406155
-
A method for the assessment of disease associations with single-nucleotide polymorphism haplotypes and environmental variables in case-control studies
-
Zhao LP, Li SS, Khalid N. A method for the assessment of disease associations with single-nucleotide polymorphism haplotypes and environmental variables in case-control studies. Am J Hum Genet 2003;72:1231-1250.
-
(2003)
Am J Hum Genet
, vol.72
, pp. 1231-1250
-
-
Zhao, L.P.1
Li, S.S.2
Khalid, N.3
-
26
-
-
20444420103
-
An LRRK2 mutation as a cause for the parkinsonism in the original PARK8 family
-
Funayama M, Hasegawa K, Ohta E, et al. An LRRK2 mutation as a cause for the parkinsonism in the original PARK8 family. Ann Neurol 2005;57:918-921.
-
(2005)
Ann Neurol
, vol.57
, pp. 918-921
-
-
Funayama, M.1
Hasegawa, K.2
Ohta, E.3
-
27
-
-
33645130652
-
Clinicogenetic study of mutations in LRRK2 exon 41 in Parkinson's disease patients from 18 countries
-
Tomiyama H, Li Y, Funayama M, et al. Clinicogenetic study of mutations in LRRK2 exon 41 in Parkinson's disease patients from 18 countries. Mov Disord 2006;21:1102-1108.
-
(2006)
Mov Disord
, vol.21
, pp. 1102-1108
-
-
Tomiyama, H.1
Li, Y.2
Funayama, M.3
-
28
-
-
24644486896
-
A clinic-based study of the LRRK2 gene in Parkinson disease yields new mutations
-
Zabetian CP, Samii A, Mosley AD, et al. A clinic-based study of the LRRK2 gene in Parkinson disease yields new mutations. Neurology 2005;65:741-744.
-
(2005)
Neurology
, vol.65
, pp. 741-744
-
-
Zabetian, C.P.1
Samii, A.2
Mosley, A.D.3
-
29
-
-
0003428818
-
-
Goodman RM, Motulsky AG, eds, New York: Raven Press;
-
Goodman RM, Motulsky AG, eds. Genetic diseases among Ashkenazi Jews. New York: Raven Press; 1979.
-
(1979)
Genetic diseases among Ashkenazi Jews
-
-
-
30
-
-
33750330251
-
Clinical and pathologic features of families with LRRK2-associated Parkinson's disease
-
Whaley NR, Uitti RJ, Dickson DW, Farrer MJ, Wszolek ZK. Clinical and pathologic features of families with LRRK2-associated Parkinson's disease. J Neural Transm Suppl 2006;221-229.
-
(2006)
J Neural Transm Suppl
, pp. 221-229
-
-
Whaley, N.R.1
Uitti, R.J.2
Dickson, D.W.3
Farrer, M.J.4
Wszolek, Z.K.5
-
31
-
-
33745034020
-
Parkinson's disease: The genetics of a heterogeneous disorder
-
Gosal D, Ross OA, Toft M. Parkinson's disease: the genetics of a heterogeneous disorder. Eur J Neurol 2006;13:616-627.
-
(2006)
Eur J Neurol
, vol.13
, pp. 616-627
-
-
Gosal, D.1
Ross, O.A.2
Toft, M.3
-
32
-
-
33646271123
-
Parkinson's disease and LRRK2: Frequency of a common mutation in U.S. movement disorder clinics
-
Kay DM, Zabetian CP, Factor SA, et al. Parkinson's disease and LRRK2: frequency of a common mutation in U.S. movement disorder clinics. Mov Disord 2006;21:519-523.
-
(2006)
Mov Disord
, vol.21
, pp. 519-523
-
-
Kay, D.M.1
Zabetian, C.P.2
Factor, S.A.3
-
33
-
-
1642482940
-
Are men at greater risk for Parkinson's disease than women?
-
Wooten GF, Currie LJ, Bovbjerg VE, Lee JK, Patrie J. Are men at greater risk for Parkinson's disease than women? J Neurol Neurosurg Psychiatry 2004;75:637-639.
-
(2004)
J Neurol Neurosurg Psychiatry
, vol.75
, pp. 637-639
-
-
Wooten, G.F.1
Currie, L.J.2
Bovbjerg, V.E.3
Lee, J.K.4
Patrie, J.5
-
34
-
-
33845210839
-
Validity and utility of a LRRK2 G2019S mutation test for the diagnosis of Parkinson's disease
-
Kay DM, Bird TD, Zabetian CP, et al. Validity and utility of a LRRK2 G2019S mutation test for the diagnosis of Parkinson's disease. Genet Test 2006;10:221-227.
-
(2006)
Genet Test
, vol.10
, pp. 221-227
-
-
Kay, D.M.1
Bird, T.D.2
Zabetian, C.P.3
|