Dry adsorbed emulsion of simvastatin: Optimization and in vivo advantage

Pharmaceutical Development and Technology

Volumn 12, Issue 5, 2007, Pages 495-504

  Dixit, Rahul P ^a   Nagarsenker, Mangal S ^a  

^a BOMBAY COLLEGE OF PHARMACY   (India)

Author keywords

Colloidal silicon dioxide; Dry adsorbed emulsion; Hyperlipidemia; Simvastatin

Indexed keywords

CAPRYOL 90; CHOLESTEROL; CREMOPHOR; HIGH DENSITY LIPOPROTEIN; POLOXAMER; POLOXAMER F127; POLYSORBATE 80; PROPANEDIOL DERIVATIVE; PROPYLENE GLYCOL MONOCAPRYLATE; SILICON DIOXIDE; SIMVASTATIN; SOYBEAN OIL EMULSION; UNCLASSIFIED DRUG;

ADSORPTION; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; COMPARATIVE STUDY; CONTROLLED STUDY; DIFFERENTIAL SCANNING CALORIMETRY; DISSOLUTION; DRUG FORMULATION; DRUG SOLUBILITY; EMULSION; FEMALE; HYPERLIPIDEMIA; NONHUMAN; POWDER; PRECIPITATION; PRIORITY JOURNAL; RAT; SCANNING ELECTRON MICROSCOPY; SOLUBILIZATION; VISCOSITY; X RAY DIFFRACTION;

ACRYLATES; ADSORPTION; ANIMALS; ANTICHOLESTEREMIC AGENTS; BIOLOGICAL AVAILABILITY; CALORIMETRY, DIFFERENTIAL SCANNING; CHOLESTEROL; EMULSIONS; FEMALE; GLYCEROL; HYPERLIPIDEMIAS; LIPOPROTEINS, HDL; MICROSCOPY, ELECTRON, SCANNING; PARTICLE SIZE; POLYSORBATES; POWDERS; RATS; RATS, SPRAGUE-DAWLEY; RHEOLOGY; SILICON DIOXIDE; SIMVASTATIN; SOLUBILITY; SOYBEAN OIL; VISCOSITY; X-RAY DIFFRACTION;

EID: 35748979437     PISSN: 10837450     EISSN: 10979867     Source Type: Journal    
DOI: 10.1080/10837450701557246     Document Type: Article

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