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Volumn 132, Issue 4, 2007, Pages 405-417

Metabolic flux analysis using stoichiometric models for Aspergillus niger: Comparison under glucoamylase-producing and non-producing conditions

Author keywords

Alpha glucoamylase; Aspergillus niger; Metabolic model; Oxalate

Indexed keywords

CARBON; GLUCOSE; MATHEMATICAL MODELS; METABOLISM; PH EFFECTS; PHOSPHATES; STOICHIOMETRY;

EID: 35748961992     PISSN: 01681656     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.jbiotec.2007.08.034     Document Type: Article
Times cited : (17)

References (48)
  • 1
    • 0034610099 scopus 로고    scopus 로고
    • Metabolism of citric acid production by Aspergillus niger: model definition, steady-state analysis and constrained optimization of citric acid production rate
    • Alvarez-Vasquez F., Gonzalez-Alcon C., and Torres N.V. Metabolism of citric acid production by Aspergillus niger: model definition, steady-state analysis and constrained optimization of citric acid production rate. Biotechnol. Bioeng. 70 (2000) 82-108
    • (2000) Biotechnol. Bioeng. , vol.70 , pp. 82-108
    • Alvarez-Vasquez, F.1    Gonzalez-Alcon, C.2    Torres, N.V.3
  • 2
    • 0025405549 scopus 로고
    • Plasmid-encoded protein: the principal factor in the 'metabolic burden' associated with recombinant bacteria
    • Bentley W., Mirjalili N., Andersen D., Davis R., and Kompala D. Plasmid-encoded protein: the principal factor in the 'metabolic burden' associated with recombinant bacteria. Biotechnol. Bioeng. 35 (1990) 668-681
    • (1990) Biotechnol. Bioeng. , vol.35 , pp. 668-681
    • Bentley, W.1    Mirjalili, N.2    Andersen, D.3    Davis, R.4    Kompala, D.5
  • 3
    • 0014287675 scopus 로고
    • Systems used for the transport of substrates into mitochondria
    • Chappel J.B. Systems used for the transport of substrates into mitochondria. Br. Med. Bull. 24 (1968) 150-157
    • (1968) Br. Med. Bull. , vol.24 , pp. 150-157
    • Chappel, J.B.1
  • 4
    • 77049312999 scopus 로고
    • Studies on the formation of oxalic acid by Aspergillus niger
    • Cleland W.W., and Johnson M.J. Studies on the formation of oxalic acid by Aspergillus niger. J. Biol. Chem. 220 (1956) 595-606
    • (1956) J. Biol. Chem. , vol.220 , pp. 595-606
    • Cleland, W.W.1    Johnson, M.J.2
  • 5
    • 0242267924 scopus 로고    scopus 로고
    • Reconstruction of the central carbon metabolism of Aspergillus niger
    • David H., Akesson M., and Nielsen J. Reconstruction of the central carbon metabolism of Aspergillus niger. Eur. J. Biochem. 270 (2003) 4243-4253
    • (2003) Eur. J. Biochem. , vol.270 , pp. 4243-4253
    • David, H.1    Akesson, M.2    Nielsen, J.3
  • 6
    • 33746908602 scopus 로고    scopus 로고
    • Polyol synthesis in Aspergillus niger: influence of oxygen availability, carbon and nitrogen sources on the metabolism
    • Diano A., Bekker-Jensen S., Dynesen J., and Nielsen J. Polyol synthesis in Aspergillus niger: influence of oxygen availability, carbon and nitrogen sources on the metabolism. Biotechnol. Bioeng. 94 (2006) 899-908
    • (2006) Biotechnol. Bioeng. , vol.94 , pp. 899-908
    • Diano, A.1    Bekker-Jensen, S.2    Dynesen, J.3    Nielsen, J.4
  • 7
    • 0023463798 scopus 로고
    • Improvement of enzyme production in Aspergillus
    • Finkelstein D.B. Improvement of enzyme production in Aspergillus. Antonie Van Leeuwenhoek 53 (1987) 349-352
    • (1987) Antonie Van Leeuwenhoek , vol.53 , pp. 349-352
    • Finkelstein, D.B.1
  • 8
    • 0025601688 scopus 로고
    • Regulation of the glaA gene of Aspergillus niger
    • Fowler T., Berka R.M., and Ward M. Regulation of the glaA gene of Aspergillus niger. Curr. Genet. 18 (1990) 537-545
    • (1990) Curr. Genet. , vol.18 , pp. 537-545
    • Fowler, T.1    Berka, R.M.2    Ward, M.3
  • 10
    • 0008161934 scopus 로고    scopus 로고
    • Optimization of the citric acid production by Aspergillus niger through a metabolic flux balance model
    • Guebel D.V., and Torres Darias N.V. Optimization of the citric acid production by Aspergillus niger through a metabolic flux balance model. Electron. J. Biotechnol. 4 (2001) 1-17
    • (2001) Electron. J. Biotechnol. , vol.4 , pp. 1-17
    • Guebel, D.V.1    Torres Darias, N.V.2
  • 11
    • 0019293901 scopus 로고
    • The distribution of the NADPH regenerating mannitol cycle among fungal species
    • Hult K., Veide A., and Gatenbeck S. The distribution of the NADPH regenerating mannitol cycle among fungal species. Arch. Microbiol. 128 (1980) 253-255
    • (1980) Arch. Microbiol. , vol.128 , pp. 253-255
    • Hult, K.1    Veide, A.2    Gatenbeck, S.3
  • 13
    • 0038364357 scopus 로고    scopus 로고
    • Aspergillus niger citric acid accumulation: Do we understand this well working black box?
    • Karaffa L., and Kubicek C.P. Aspergillus niger citric acid accumulation: Do we understand this well working black box?. Appl. Microbiol. Biotechnol. 61 (2003) 189-196
    • (2003) Appl. Microbiol. Biotechnol. , vol.61 , pp. 189-196
    • Karaffa, L.1    Kubicek, C.P.2
  • 15
    • 0032937102 scopus 로고    scopus 로고
    • Cloning and expression of the cDNA encoding an alternative oxidase gene from Aspergillus niger WU-2223L
    • Kirimura K., Yoda M., and Usami S. Cloning and expression of the cDNA encoding an alternative oxidase gene from Aspergillus niger WU-2223L. Curr. Genet. 34 (1999) 472-477
    • (1999) Curr. Genet. , vol.34 , pp. 472-477
    • Kirimura, K.1    Yoda, M.2    Usami, S.3
  • 16
    • 0023976071 scopus 로고
    • Evidence for a cytoplasmic pathway of oxalate biosynthesis in Aspergillus niger
    • Kubicek C.P., Schreferl-Kunar G., Wohrer W., and Rohr M. Evidence for a cytoplasmic pathway of oxalate biosynthesis in Aspergillus niger. Appl. Environ. Microbiol. 54 (1988) 633-637
    • (1988) Appl. Environ. Microbiol. , vol.54 , pp. 633-637
    • Kubicek, C.P.1    Schreferl-Kunar, G.2    Wohrer, W.3    Rohr, M.4
  • 18
    • 0002596901 scopus 로고    scopus 로고
    • Filamentous fungi as production organisms for glycoproteins of bio-medical interest
    • Maras M., van Die I., Contreras R., and van den Hondel C.A. Filamentous fungi as production organisms for glycoproteins of bio-medical interest. Glycoconj. J. 16 (1999) 99-107
    • (1999) Glycoconj. J. , vol.16 , pp. 99-107
    • Maras, M.1    van Die, I.2    Contreras, R.3    van den Hondel, C.A.4
  • 20
    • 0020794664 scopus 로고
    • The sub-cellular localisation of pyruvate carboxylase and of some other enzymes in Aspergillus nidulans
    • Osmani S.A., and Scrutton M.C. The sub-cellular localisation of pyruvate carboxylase and of some other enzymes in Aspergillus nidulans. Eur. J. Biochem. 133 (1983) 551-560
    • (1983) Eur. J. Biochem. , vol.133 , pp. 551-560
    • Osmani, S.A.1    Scrutton, M.C.2
  • 21
    • 0032931265 scopus 로고    scopus 로고
    • Identification of enzymes and quantification of metabolic fluxes in the wild type and in a recombinant Aspergillus oryzae strain
    • Pedersen H., Carlsen M., and Nielsen J. Identification of enzymes and quantification of metabolic fluxes in the wild type and in a recombinant Aspergillus oryzae strain. Appl. Environ. Microbiol. 65 (1999) 11-19
    • (1999) Appl. Environ. Microbiol. , vol.65 , pp. 11-19
    • Pedersen, H.1    Carlsen, M.2    Nielsen, J.3
  • 22
    • 14844349363 scopus 로고    scopus 로고
    • metaSHARK: software for automated metabolic network prediction from DNA sequence and its application to the genomes of Plasmodium falciparum and Eimeria tenella
    • Pinney J.W., Shirley M.W., McConkey G.A., and Westhead D.R. metaSHARK: software for automated metabolic network prediction from DNA sequence and its application to the genomes of Plasmodium falciparum and Eimeria tenella. Nucleic Acids Res. 33 (2005) 1399-1409
    • (2005) Nucleic Acids Res. , vol.33 , pp. 1399-1409
    • Pinney, J.W.1    Shirley, M.W.2    McConkey, G.A.3    Westhead, D.R.4
  • 23
    • 0027234348 scopus 로고
    • The role of the proton-pumping and alternative respiratory chain NADH:ubiquinone oxidoreductases in overflow catabolism of Aspergillus niger
    • Promper C., Schneider R., and Weiss H. The role of the proton-pumping and alternative respiratory chain NADH:ubiquinone oxidoreductases in overflow catabolism of Aspergillus niger. Eur. J. Biochem. 216 (1993) 223-230
    • (1993) Eur. J. Biochem. , vol.216 , pp. 223-230
    • Promper, C.1    Schneider, R.2    Weiss, H.3
  • 25
    • 0032832111 scopus 로고    scopus 로고
    • Oxalic acid production by Aspergillus niger: an oxalate-non-producing mutant produces citric acid at pH 5 and in the presence of manganese
    • Ruijter G.J., van de Vondervoort P.J., and Visser J. Oxalic acid production by Aspergillus niger: an oxalate-non-producing mutant produces citric acid at pH 5 and in the presence of manganese. Microbiology 145 (1999) 2569-2576
    • (1999) Microbiology , vol.145 , pp. 2569-2576
    • Ruijter, G.J.1    van de Vondervoort, P.J.2    Visser, J.3
  • 26
    • 0038079923 scopus 로고    scopus 로고
    • Oxalic acid production from lipids by a mutant of Aspergillus niger at different pH
    • Rymowicz W., and Lenart D. Oxalic acid production from lipids by a mutant of Aspergillus niger at different pH. Biotechnol. Lett. 25 (2003) 955-958
    • (2003) Biotechnol. Lett. , vol.25 , pp. 955-958
    • Rymowicz, W.1    Lenart, D.2
  • 27
    • 0027332212 scopus 로고
    • Growth and product formation in chemostat and recycling cultures by Aspergillus niger N402 and a glucoamylase overproducing transformant, provided with multiple copies of the glaA gene
    • Schrickx J.M., Krave A.S., Verdoes J.C., van den Hondel C.A., Stouthamer A.H., and van Verseveld H.W. Growth and product formation in chemostat and recycling cultures by Aspergillus niger N402 and a glucoamylase overproducing transformant, provided with multiple copies of the glaA gene. J. Gen. Microbiol. 139 (1993) 2801-2810
    • (1993) J. Gen. Microbiol. , vol.139 , pp. 2801-2810
    • Schrickx, J.M.1    Krave, A.S.2    Verdoes, J.C.3    van den Hondel, C.A.4    Stouthamer, A.H.5    van Verseveld, H.W.6
  • 29
    • 32544444888 scopus 로고    scopus 로고
    • Optimization of glucoamylase production by Aspergillus niger in solid-state fermentation
    • Silveira S.T., Oliveira M.S., Costa J.A., and Kalil S.J. Optimization of glucoamylase production by Aspergillus niger in solid-state fermentation. Appl. Biochem. Biotechnol. 128 (2006) 131-140
    • (2006) Appl. Biochem. Biotechnol. , vol.128 , pp. 131-140
    • Silveira, S.T.1    Oliveira, M.S.2    Costa, J.A.3    Kalil, S.J.4
  • 30
    • 0028272233 scopus 로고
    • Characterization and regulatory properties of a single hexokinase from the citric acid accumulating fungus Aspergillus niger
    • Steinbock F., Choojun S., Held I., Roehr M., and Kubicek C.P. Characterization and regulatory properties of a single hexokinase from the citric acid accumulating fungus Aspergillus niger. Biochim. Biophys. Acta 1200 (1994) 215-223
    • (1994) Biochim. Biophys. Acta , vol.1200 , pp. 215-223
    • Steinbock, F.1    Choojun, S.2    Held, I.3    Roehr, M.4    Kubicek, C.P.5
  • 32
    • 0028301503 scopus 로고
    • High-yield production of oxalic acid for metal leaching processes by Aspergillus niger
    • Strasser H., Burgstaller W., and Schinner F. High-yield production of oxalic acid for metal leaching processes by Aspergillus niger. FEMS Microbiol. Lett. 119 (1994) 365-370
    • (1994) FEMS Microbiol. Lett. , vol.119 , pp. 365-370
    • Strasser, H.1    Burgstaller, W.2    Schinner, F.3
  • 33
    • 35748972783 scopus 로고    scopus 로고
    • IdentiCS-A program to identify coding sequence from unnotated low-coverage genome sequences
    • Bielefeld
    • Sun J., and Zeng A.-P. IdentiCS-A program to identify coding sequence from unnotated low-coverage genome sequences. GCB'04: German Conference on Bioinformatics. Bielefeld (2004)
    • (2004) GCB'04: German Conference on Bioinformatics
    • Sun, J.1    Zeng, A.-P.2
  • 34
    • 0024063815 scopus 로고
    • Application of metabolic pathway stoichiometry to statistical analysis of bioreactor measurement data
    • Tsai S.P., and Lee Y.H. Application of metabolic pathway stoichiometry to statistical analysis of bioreactor measurement data. Biotechnol. Bioeng. 32 (1988) 713-715
    • (1988) Biotechnol. Bioeng. , vol.32 , pp. 713-715
    • Tsai, S.P.1    Lee, Y.H.2
  • 35
    • 33749133230 scopus 로고    scopus 로고
    • Metabolic flux distributions in Corynebacterium glutamicum during growth and lysine overproduction
    • Vallino J.J., and Stephanopoulos G. Metabolic flux distributions in Corynebacterium glutamicum during growth and lysine overproduction. Biotechnol. Bioeng. 67 (2000) 872-885
    • (2000) Biotechnol. Bioeng. , vol.67 , pp. 872-885
    • Vallino, J.J.1    Stephanopoulos, G.2
  • 38
    • 0026605105 scopus 로고
    • Production of extracellular proteins by the filamentous fungus Aspergillus
    • van den Hondel C.A., Punt P.J., and van Gorcom R.F. Production of extracellular proteins by the filamentous fungus Aspergillus. Antonie Van Leeuwenhoek 61 (1992) 153-160
    • (1992) Antonie Van Leeuwenhoek , vol.61 , pp. 153-160
    • van den Hondel, C.A.1    Punt, P.J.2    van Gorcom, R.F.3
  • 39
    • 35748950836 scopus 로고
    • Linear constraint relations in biochemical reactions systems: II. Diagnosis and estimation of gross measurement errors
    • van der Heijden R.T.J.M., Heijnen J.J., Hellinga C., Romein B., and Luyben K.CH.A.M. Linear constraint relations in biochemical reactions systems: II. Diagnosis and estimation of gross measurement errors. Biotech. Bioeng. 61 (1993) 11-20
    • (1993) Biotech. Bioeng. , vol.61 , pp. 11-20
    • van der Heijden, R.T.J.M.1    Heijnen, J.J.2    Hellinga, C.3    Romein, B.4    Luyben, K.CH.A.M.5
  • 41
    • 2342540411 scopus 로고    scopus 로고
    • Aspergillus niger mstA encodes a high-affinity sugar/H+ symporter which is regulated in response to extracellular pH
    • van Kuyk P.A., Diderich J.A., MacCabe A.P., Hererro O., Ruijter G.J., and Visser J. Aspergillus niger mstA encodes a high-affinity sugar/H+ symporter which is regulated in response to extracellular pH. Biochem. J. 379 (2004) 375-383
    • (2004) Biochem. J. , vol.379 , pp. 375-383
    • van Kuyk, P.A.1    Diderich, J.A.2    MacCabe, A.P.3    Hererro, O.4    Ruijter, G.J.5    Visser, J.6
  • 42
    • 0028146781 scopus 로고
    • Stoichiometric flux balance models quantitatively predict growth and metabolic by-product secretion in wild-type Escherichia coli W3110
    • Varma A., and Palsson B.O. Stoichiometric flux balance models quantitatively predict growth and metabolic by-product secretion in wild-type Escherichia coli W3110. Appl. Environ. Microbiol. 60 (1994) 3724-3731
    • (1994) Appl. Environ. Microbiol. , vol.60 , pp. 3724-3731
    • Varma, A.1    Palsson, B.O.2
  • 43
    • 0022309374 scopus 로고
    • Changes in the activity of Krebs cycle enzymes in an Aspergillus niger strain during the biosynthesis of citric acid
    • Vasilev N., Vasileva M., and Ganchev I. Changes in the activity of Krebs cycle enzymes in an Aspergillus niger strain during the biosynthesis of citric acid. Acta Microbiol. Bulg. 17 (1985) 46-51
    • (1985) Acta Microbiol. Bulg. , vol.17 , pp. 46-51
    • Vasilev, N.1    Vasileva, M.2    Ganchev, I.3
  • 44
    • 0001963676 scopus 로고
    • A convenient growth medium for Neurospora (Medium N)
    • Vogel H. A convenient growth medium for Neurospora (Medium N). Microbial. Genet. Bull. 243 (1956) 112-119
    • (1956) Microbial. Genet. Bull. , vol.243 , pp. 112-119
    • Vogel, H.1
  • 46
    • 0034741983 scopus 로고    scopus 로고
    • 13C metabolic flux analysis
    • Wiechert W. 13C metabolic flux analysis. Metab. Eng. 3 (2001) 195-206
    • (2001) Metab. Eng. , vol.3 , pp. 195-206
    • Wiechert, W.1
  • 47
    • 0029689236 scopus 로고    scopus 로고
    • In vivo stationary flux analysis by 13C labeling experiments
    • Wiechert W., and de Graaf A.A. In vivo stationary flux analysis by 13C labeling experiments. Adv. Biochem. Eng. Biotechnol. 54 (1996) 109-154
    • (1996) Adv. Biochem. Eng. Biotechnol. , vol.54 , pp. 109-154
    • Wiechert, W.1    de Graaf, A.A.2


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