Poor glycaemic control is the major factor associated with increased frequency of gastrointestinal symptoms in patients with diabetes mellitus

Journal of the Pakistan Medical Association

Volumn 57, Issue 7, 2007, Pages 345-349

  Abid, Shahab ^a   Rizvi, Amir ^a   Jahan, Firdous ^a   Rabbani, Fauziah ^b   Islam, Najmul ^a   Khan, Masood H ^c   Masood, Rana ^c   Jafri, Wasim ^a  

^a AGA KHAN UNIVERSITY HOSPITAL   (Pakistan)

^b AGA KHAN UNIVERSITY   (Pakistan)

^c CIVIL HOSPITAL   (Pakistan)

Author keywords

[No Author keywords available]

Indexed keywords

GLUCOSE; HEMOGLOBIN A1C;

ABDOMINAL PAIN; ADULT; ARTICLE; CONSTIPATION; CONTROLLED STUDY; DEMOGRAPHY; DIABETIC NEUROPATHY; DIABETIC PATIENT; DIABETIC RETINOPATHY; DIARRHEA; DISEASE DURATION; DISEASE SEVERITY; DYSPEPSIA; FECES INCONTINENCE; FEMALE; GASTROINTESTINAL SYMPTOM; GLYCEMIC CONTROL; HEARTBURN; HUMAN; MAJOR CLINICAL STUDY; MALE; PATIENT ASSESSMENT; PATIENT ATTITUDE; PROSPECTIVE STUDY; QUESTIONNAIRE; CASE CONTROL STUDY; COMPARATIVE STUDY; DIABETES MELLITUS; GASTROINTESTINAL DISEASE; GASTROINTESTINAL TRACT; GLUCOSE BLOOD LEVEL; GLYCEMIC INDEX; MIDDLE AGED; PATHOPHYSIOLOGY; RISK FACTOR;

BLOOD GLUCOSE; CASE-CONTROL STUDIES; DIABETES COMPLICATIONS; FEMALE; GASTROINTESTINAL DISEASES; GASTROINTESTINAL TRACT; GLYCEMIC INDEX; HUMANS; MALE; MIDDLE AGED; PROSPECTIVE STUDIES; RISK FACTORS;

EID: 35748950434     PISSN: 00309982     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (19)

1. Agreus L, Svardsudd K, Nyren O, Tibblin G. Irritable bowel syndrome and dyspepsia in the general population: overlap and lack of stability overtime. Gastroenterology 1995; 109:671-80.
2. Lluch I, Ascaso JF, Mora F, Minguez M, Pena A, Hernandez A et al. Gastroesophageal reflux in diabetes mellitus. Am J gastroenterol 1999; 94:919-24.
3. Maleki D, Locke GR, Camilleri M, Zinsmeister AR, Yawn BP, Leibson C et al. Gastrointestinal tract symptoms among persons with diabetes mellitus in the community. Arch Intern Med 2000; 160:2808-16.
4. Bytzer P, Talley NJ, Leemon M, Young LJ, Jones MP, Horowitz M. Prevalence of Gastrointestinal symptoms associated with diabetes mellitus. A population based survey of 15,000 adults. Arch Intern Med 2001; 161:1989-96.
5. Ko GT, Chan WB, Chan JC, Tsang LW, Cockram CS. Gastrointestinal symptoms in Chinese patients with type-2 diabetes mellitus. Diabet Med 1999; 16:670-4.
6. Enck P, Rathmann W, Spiekermann M, Czerner D, Tschope D, Zeigler D et al. Prevalence of gastrointestinal symptoms in diabetic patients and non-diabetic subjects. Z Gastroenterol 1994; 32:637-41.
7. Zhang Q, Horowitz M, Rigda R, Rayner C, Worynski A, Holloway RH. Effect of hyperglycemia on triggerng of transient lower esophageal sphincter relaxations. Am J Physiol Gastrointest Liver Physiol 2004; 286:797-803.
8. Gulcelik NE, Kaya E, Demirbas B, Culha C, Koc G, Ozkaya M, el al. Helicobacter pylori prevalence in diabetic patients and its relationship with dyspepsia and autonomic neuropathy. J Endocrinol Invest. 2005; 28:214-7.
9. Laakso M, Pyorala K. Age of onset and type of diabetes. Diabetes Care 1985; 8:114-7.
10. Talley NJ, Phillips SF, Melton J, Wiltgen C, Zinsmiester AR. A patient questionnaire to identify bowel disease. Ann Intern Med. 1989; 111:671-4
11. Feldman M, Schiller LR. Disorders of gastrointestinal motility associated with diabetes mellitus. Ann Intern Med 1983; 98:378-84.
12. Rayner CK, Smout AJ, Sun WM, Russo A, Semmler J, Sattawatthamrong Y et al. Effects of hyperglycemia on cortical response to esophageal distension in normal subjects. Dig Dis Sci. 1999; 44:279-85.
13. Samsom M, Akkermans LM, Jebbink RJ, Van Isselt H, Van Berge-Henegouwen GP, Smout AJ. Gastrointestinal motor mechanism in hyperglycemia induced delayed gastric emptying in type I diabetes mellitus. Gut 1997; 40:641-6.
14. Jones KL, Horowitz M, Berry M, Wishart JM Guha S. Blood glucose concentration influences postprandial fullness in IDDM. Diabetes Care 1997; 20:1141-6.
15. Horowitz M, Harding PE, Maddox AF, Wishart JM, Akkermans LM, Chattterton BE et al. Gastric and esophageal emptying in patients with type-2 (non-insulin dependent) diabetes mellitus. Diabetologia 1989; 32:151-9.
16. de Boer SY, Masclee AA, Lam WF, Lamers CB. Effect of acute hyperglycemia on esophageal motility and lower esophageal sphincter pressure in humans. Gastroenterology 1992; 103:775-80.
17. Bytzer P, Talley NJ, Hammer J, Young LJ, Jones MP, Horowitz M. GI symptoms in diabetes mellitus are associated with both poor glycemic control and diabetic complications. Am J Gastroenterol 2002; 97:604-11
18. Granberg V, Ejskjaer N, Peakman M, Sundkvist G. Autoantibodies to autonomic nerves associated with cardiac and peripheral autonomic neuropathy. Diabetes Care 2005; 28: 1959-64
19. Bytzer P, Talley NJ, Jones MP, Horowitz M. Oral hypoglycemic drugs and gastrointestinal symptoms in diabetes mellitus. Aliment Pharmacol Ther. 2001; 15:137-42.