Gastrointestinal motor mechanisms in hyperglycaemia induced delayed gastric emptying in type I diabetes mellitus

Gut

Volumn 40, Issue 5, 1997, Pages 641-646

  Samsom, M ^a   Akkermans, L M A ^a   Jebbink, R J A ^a   Van Isselt, H ^a   VanBerge Henegouwen, G P ^a   Smout, A J P M ^a  

^a UNIVERSITY MEDICAL CENTER UTRECHT   (Netherlands)

Author keywords

Antroduodenal motility; Diabetes mellitus; Hyperglycaemia; Scintigraphic gastric emptying

Indexed keywords

ADULT; AGED; ARTICLE; CLINICAL ARTICLE; CLINICAL TRIAL; CONTROLLED CLINICAL TRIAL; CONTROLLED STUDY; DUODENUM MOTILITY; FEMALE; FUNCTIONAL ASSESSMENT; HUMAN; HYPERGLYCEMIA; INSULIN DEPENDENT DIABETES MELLITUS; LIQUID; MALE; MEAL; PATHOPHYSIOLOGY; POSTPRANDIAL STATE; PRIORITY JOURNAL; RANDOMIZED CONTROLLED TRIAL; SOLID; STOMACH EMPTYING;

EID: 0030912692     PISSN: 00175749     EISSN: None     Source Type: Journal    
DOI: 10.1136/gut.40.5.641     Document Type: Article

References (27)

1. Kassander P. Asymptomatic gastric retention in diabetics (gastroparesis diabeticorum). Ann Int Med 1958; 48: 797-812.
2. Horowitz M, Harding M, Maddox A, et al. Gastric and esophageal emptying in insulin-dependent diabetes mellitus. J Gastroenterol Hepatol 1986; 1: 97-113.
3. Keshavarzian A, Iber FL, Vaeth J. Gastric emptying in patients with insuline-requiring diabetes mellitus. Am J Gastroenterol 1986; 82: 29-35.
4. Camilleri M, Malagelada J-R. Abnormal intestinal motility in diabetes with gastroparesis syndrome. Eur J Clin Invest 1984; 14: 420-7.
5. Jebbink HJA, Bravenboer B, Akkermans LMA, van Berge-Henegouwen GP, Smout AJPM. Relationship between dyspeptic symptoms and gastrointestinal motility in patients with type I (insulin-dependent) diabetes mellitus. Diabetologia 1993; 36: 948-54.
6. Mearin F, Camilleri M, Malagelada JR. Pyloric dysfunction in diabetics with recurrent nausea and vomiting. Gastroenterology 1986; 90: 1919-25.
7. Feldman M, Schiller LR. Disorders of gastrointestinal motility associated with diabetes mellitus. Ann Int Med 1983; 98: 378-84.
8. Parkman HP, Schwartz SS. Esophagitis and gastroduodenal disorders associated with diabetes mellitus. Arch Intern Med 1987; 147: 1477-80.
9. Horowitz M, Edelbroek M, Fraser R, Maddox A, Wishart J. Disordered gastric motor function in diabetes mellitus. Recent insights into prevalence, pathophysiology, clinical relevance and treatment. Scand J Gastroenterol 1991; 26: 673-84.
10. Rundles RW. Diabetic neuropathy; general review with reports of 125 cases. Medicine 1945; 24: 111-60.
11. Fraser RJ, Horowitz M, Maddox AF, Harding PE, Chatterton BE, Dent J. Hyperglycaemia slows gastric emptying in type 1 (insulin-dependent) diabetes mellitus. Diabetologia 1990; 33: 675-80.
12. Fraser RJ, Horowitz M, Dent J. Hyperglycemia stimulates pyloric motility in normal subjects. Gut 1990; 32: 475-8.
13. Barnett JL, Owyang C. Serum glucose concentration as a modulator of interdigestive gastric motility. Gastroenterology 1988; 94: 739-44.
14. Hasler WL, Soudah HC, Dulai G, Owyang C. Mediation of hyperglycemia-evoked gastric slow-wave dysrhythmias by endogenous prostaglandins. Gastroenterology 1995; 108: 727-36.
15. Lam WF, De Boer SY, Masclee AAM, Lamers CBHW. Hyperglycemia reduces gastric secretory and plasma pancreatic polypeptide responses to modified sham feeding. Digestion 1993; 54: 48-53.
16. Ewing DJ, Clarke BF. Diagnosis and management of diabetic autonomie neuropathy. BMJ 1982; 285: 916-8.
17. Heddle R, Fone D, Dent J, Horowitz M. Stimulation of pyloric motility by intraduodenal dextrose in normal subjects. Gut 1988; 29: 1349-57.
18. Samsom M, Jebbink HJA, Akkermans LMA, van Berge-Henegouwen GP, Smout AJPM. Abnormalities of antroduodenal motility in type I (insulin-dependent) diabetes mellitus. Diabetes Care 1996; 19: 21-7.
19. Smout AJPM, Bogaard JW, van Hattum J, Akkermans LMA. Effects of cimetidine and ranitidine on interdigestive and postprandial lower esophageal sphincter pressure and plasma gastrin levels in normal subjects. Gastroenterology 1985; 88: 557-63.
20. Fraser R, Horowitz M, Maddox M, Dent J. Organization of antral, pyloric and duodenal motility in patients with gastroparesis. J Gastrointest Motil 1993; 5: 167-75.
21. Collins PJ, Horowitz M, Cook DJ, Harding PE, Shearman DJC. Gastric emptying in normal subjects. A reproducible technique using a single scintillation camera. Gut 1983; 24: 1117-25.
22. Fone DR, Horowitz M, Heddle R, Maddox AF, Collins PJ, Read NW, Dent J. Comparative effects of duodenal and ileal intubation on gastric emptying and postprandial antral, pyloric and duodenal motility. Scand J Gastroenterol 1991; 26: 16-22.
23. DeFronzo RA, Tobin JD, Andres R. Glucose clamp technique: a method for quantifying insulin secretion and resistance. Am J Physiol 1979; 237: E214-23.
24. MacGregor, Gueller R, Watts HD, Meyer JH. The effect of acute hyperglycemia on gastric emptying in man. Gastroenterology 1976; 70: 190-6.
25. Camilleri M, Malagelada JR, Brown ML, Becker G, Zinsmeister AR. Relation between antral motility and gastric emptying of solids and liquids in humans. Am J Physiol 1985; 249: G580-5.
26. Houghton LA, Read NW, Heddle R, Horowitz M, Collins PJ, Chatterton B, Dent J. Relationship of the motor activity of the antrum, pylorus and duodenum to gastric emptying of a solid-liquid mixed meal. Gastroenterology 1988; 94: 1285-91.
27. Hebbard G, Samsom M, Sun WM, Dent J, Horowitz M. Hyperglycemia affects proximal gastric motor and sensory function during small intestinal nutrient infusion. Gastroenterology 1996; 110: A676.