Clinical trial: Sodium phosphate tablets are preferred and better tolerated by patients compared to polyethylene glycol solution plus bisacodyl tablets for bowel preparation

Alimentary Pharmacology and Therapeutics

Volumn 26, Issue 10, 2007, Pages 1361-1370

  Lichtenstein, G R ^a,f   Grandhi, N ^b   Schmalz, M ^c   Lottes, S R ^d   Forbes, W P ^d   Walker, K ^d   Zhang, B ^e  

^a UNIVERSITY OF PENNSYLVANIA   (United States)

^b Greater Cincinnati Gastroenterology Associates   (United States)

^c Wisconsin Center for Advanced Research   (United States)

^d Salix Pharmaceuticals Inc ^*  (United States)

^e MacroStat Inc   (United States)

^f HOSPITAL OF THE UNIVERSITY OF PENNSYLVANIA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BISACODYL; MACROGOL; SODIUM DIHYDROGEN PHOSPHATE;

ABDOMINAL CRAMP; ABDOMINAL PAIN; ADULT; ARTICLE; BLOATING; CLINICAL TRIAL; COLON CANCER; COLONOSCOPY; CONTROLLED CLINICAL TRIAL; CONTROLLED STUDY; DAILY LIFE ACTIVITY; DRUG CHOICE; DRUG DOSE REGIMEN; DRUG EFFICACY; DRUG FORMULATION; DRUG TOLERABILITY; FEMALE; HUMAN; INTESTINE PREPARATION; LIQUID; MALE; MULTICENTER STUDY; NAUSEA; NORMAL HUMAN; PATIENT ATTITUDE; PATIENT SAFETY; PHASE 3 CLINICAL TRIAL; PRESCRIPTION; PRIORITY JOURNAL; PROSPECTIVE STUDY; QUESTIONNAIRE; RANDOMIZED CONTROLLED TRIAL; SINGLE BLIND PROCEDURE; STATISTICAL SIGNIFICANCE; TASTE; VOMITING;

ADOLESCENT; ADULT; AGED; BISACODYL; CATHARTICS; COLONIC DISEASES; COLONOSCOPY; DRUG CARRIERS; FEMALE; HUMANS; MALE; MIDDLE AGED; PATIENT SATISFACTION; PHOSPHATES; POLYETHYLENE GLYCOLS; PREOPERATIVE CARE; TREATMENT OUTCOME;

EID: 35748936738     PISSN: 02692813     EISSN: 13652036     Source Type: Journal    
DOI: 10.1111/j.1365-2036.2007.03496.x     Document Type: Article

References (15)

1. Imperiale TF, Wagner DR, Lin CY, Larkin GN, Rogge JD, Ransohoff DF. Risk of advanced proximal neoplasms in asymptomatic adults according to the distal colorectal findings. N Engl J Med 2000 343 : 169 74.
2. Winawer SJ, Stewart ET, Zauber AG, et al. A comparison of colonoscopy and double-contrast barium enema for surveillance after polypectomy. National Polyp Study Work Group. N Engl J Med 2000 342 : 1766 72.
3. Lieberman DA, Weiss DG, Bond JH, Ahnen DJ, Garewal H, Chejfec G. Use of colonoscopy to screen asymptomatic adults for colorectal cancer. Veterans Affairs Cooperative Study Group 380. N Engl J Med 2000 343 : 162 8.
4. Harewood GC, Wiersema MJ, Melton LJ III. A prospective, controlled assessment of factors influencing acceptance of screening colonoscopy. Am J Gastroenterol 2002 97 : 3186 94.
5. Johanson J, Popp J, Cohen L, et al. A randomized, multicenter study comparing the safety and efficacy of sodium phosphate tablets to 2L polyethylene glycol solution plus bisacodyl tablets for colon cleansing. Am J Gastroenterol 2007 102 : 2238 46.
6. Rex DK, Schwartz H, Goldstein M, et al. Safety and colon-cleansing efficacy of a new residue-free formulation of sodium phosphate tablets. Am J Gastroenterol 2006 101 : 2594 604.
7. Winawer S, Fletcher R, Rex D, et al. Colorectal cancer screening and surveillance: clinical guidelines and rationale-update based on new evidence. Gastroenterology 2003 124 : 544 60.
8. Kastenberg D, Barish C, Burack H, et al. Tolerability and patient acceptance of sodium phosphate tablets compared with 4-L PEG solution in colon cleansing: combined results of 2 identically designed, randomized, controlled, parallel group, multicenter phase 3 trials. J Clin Gastroenterol 2007 41 : 54 61.
9. Kastenberg D, Chasen R, Choudhary C, et al. Efficacy and safety of sodium phosphate tablets compared with PEG solution in colon cleansing: two identically designed, randomized, controlled, parallel group, multicenter phase III trials. Gastrointest Endosc 2001 54 : 705 13.
10. Aronchick CA, Lipshutz WH, Wright SH, Dufrayne F, Bergman G. A novel tableted purgative for colonoscopic preparation: efficacy and safety comparisons with Colyte and Fleet Phospho-Soda. Gastrointest Endosc 2000 52 : 346 52.
11. Vanner SJ, MacDonald PH, Paterson WG, Prentice RS, Da Costa LR, Beck IT. A randomized prospective trial comparing oral sodium phosphate with standard polyethylene glycol-based lavage solution (Golytely) in the preparation of patients for colonoscopy. Am J Gastroenterol 1990 85 : 422 7.
12. Cohen SM, Wexner SD, Binderow SR, et al. Prospective, randomized, endoscopic-blinded trial comparing precolonoscopy bowel cleansing methods. Dis Colon Rectum 1994 37 : 689 96.
13. Afridi SA, Barthel JS, King PD, Pineda JJ, Marshall JB. Prospective, randomized trial comparing a new sodium phosphate-bisacodyl regimen with conventional PEG-ES lavage for outpatient colonoscopy preparation. Gastrointest Endosc 1995 41 : 485 9.
14. Marshall JB, Pineda JJ, Barthel JS, King PD. Prospective, randomized trial comparing sodium phosphate solution with polyethylene glycol-electrolyte lavage for colonoscopy preparation. Gastrointest Endosc 1993 39 : 631 4.
15. Frommer D. Cleansing ability and tolerance of three bowel preparations for colonoscopy. Dis Colon Rectum 1997 40 : 100 4.