Attitudes towards predictive genetic testing in minors for familial breast cancer: A systematic review

Critical Reviews in Oncology/Hematology

Volumn 64, Issue 3, 2007, Pages 173-181

  Borry, Pascal ^a   Stultiëns, Louise ^a   Nys, Herman ^a   Dierickx, Kris ^a  

^a UNIVERSITY OF LEUVEN   (Belgium)

Author keywords

Cancer; Genetic; Minors; Oncology; Review no competing interests

Indexed keywords

ATTITUDE; BREAST CANCER; CANCER PATIENT; CANCER RISK; DATA BASE; DATA EXTRACTION; FAMILIAL CANCER; GENETIC ANALYSIS; HEALTH CARE PERSONNEL; HUMAN; JUVENILE; MEDLINE; METHODOLOGY; PARENT; RELATIVE; REVIEW; SAMPLE SIZE; SYSTEMATIC REVIEW;

ADOLESCENT; AGE FACTORS; ATTITUDE TO HEALTH; BREAST NEOPLASMS; GENETIC SCREENING; HUMANS; MINORS; PARENTS; PROGNOSIS;

EID: 35649023114     PISSN: 10408428     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.critrevonc.2007.04.006     Document Type: Review

References (38)

1. King M.C., Marks J.H., and Mandell J.B. Breast-ovarian cancer risks due to inherited mutations in BRCA1 and BRCA2. Science 302 5645 (2003) 643-646
2. Lux M.P., Fasching P.A., and Beckmann MW. Hereditary breast and ovarian cancer: review and future perspectives. J Mol Med 84 January (1) (2006) 16-28
3. Smith R.A., Cokkinides V., and Eyre H.J. American Cancer Society guidelines for the early detection of cancer. CA Cancer J Clin 56 January-February (1) (2006) 11-25
4. Committee for Public Relations and Ethical Issues of the German Society of Human Genetics. Statement on genetic diagnosis in children and adolescents. GSHG; 1995. http://www.gfhev.de/en/gfh/.
5. Danish Council of Ethics. Genetic investigation of healthy subjects. Report on presymptomatic gene diagnosis; 2001. http://www.etiskraad.dk.
6. European Society of Human Genetics. Provision of genetic services in Europe-current practices and issues; 2001. http://www.eshg.org.
7. Borry P., Schotsmans P., Fryns J.P., and Dierickx K. Carrier testing in minors: a systematic review of guidelines and positions statements. Eur J Hum Genet 14 2 (2006) 133-138
8. The American Society of Human Genetics Board of Directors and The American College of Medical Genetics Board of Directors. Points to consider: ethical, legal, and psychological implications of genetic testing in children and adolescents. Am J Hum Genet 1995;57:1233-41.
9. Clarke A. The genetic testing of children Working Party of the Clinical Genetics Society (UK). J Med Genet 31 10 (1994) 785-797
10. American Medical Association. Testing children for genetic status; 1995. http://www.ama-assn.org/.
11. Lucassen A., and Houlston R. Clinical geneticists' attitudes and practice towards testing for breast cancer susceptibility genes. J Med Genet 37 2 (2000) 157-160
12. Campbell E., and Ross L.F. Professional and personal attitudes about access and confidentiality in the genetic testing of children: a pilot study. Genet Test 7 2 (2003) 123-130
13. Welkenhuysen M., and Evers-Kiebooms G. Predictive genetic testing for breast cancer and Huntington's disease: the opinions of midwives and nurses in flanders. Commun Genet 6 2 (2003) 104-113
14. Geller G., Tambor E.S., Bernhardt B.A., Wissow L.S., and Fraser G. Mothers and daughters from breast cancer families: a qualitative study of their perceptions of risks and benefits associated with minor's participation in genetic susceptibility research. J Am Med Womens Assoc 55 5 (2000) 280-284
15. Harel A., Abuelo D., and Kazura A. Adolescents and genetic testing: what do they think about it?. J Adolesc Health 33 6 (2003) 489-494
16. Cappelli M., Verma S., Korneluk Y., et al. Psychological and genetic counseling implications for adolescent daughters of mothers with breast cancer. Clin Genet 67 6 (2005) 481-491
17. Campbell E., and Ross L.F. Parental attitudes and beliefs regarding the genetic testing of children. Commun Genet 8 2 (2005) 94-102
18. Welkenhuysen M., and Evers-Kiebooms G. The reactions of general practitioners, nurses and midwives in Flanders concerning breast cancer risks in a high-risk situation. Commun Genet 6 4 (2003) 206-213
19. Riordan S.H., and Loescher L.J. Medical students' attitudes toward genetic testing of minors. Genet Test 10 Spring (1) (2006) 68-73
20. Rowley P.T., and Loader S. Attitudes of obstetrician-gynecologists toward DNA testing for a genetic susceptibility to breast cancer. Obstet Gynecol 88 4 Pt 1 (1996) 611-615
21. Family Law Reform Act. s8 (1). Age of majority act (NI) art 4 (1); 1969.
22. British Medical Association. Human genetics: choice and responsibility (1998), Oxford University Press, Oxford
23. Borry P., Stultiens L., Nys H., Cassiman J.J., and Dierickx K. Presymptomatic and predictive genetic testing in minors: a systematic review of guidelines and position papers. Clin Genet 70 5 (2006) 374-381
24. British Medical Association. Consent rights and choices in healthcare for children and young people (2001), BMJ Books, London
25. Hamann H.A., Croyle R.T., Venne V.L., Baty B.J., Smith K.R., and Botkin J.R. Attitudes toward the genetic testing of children among adults in a Utah-based kindred tested for a BRCA1 mutation. Am J Med Genet 92 1 (2000) 25-32
26. Benkendorf J.L., Reutenauer J.E., Hughes C.A., et al. Patients' attitudes about autonomy and confidentiality in genetic testing for breast-ovarian cancer susceptibility. Am J Med Genet 73 3 (1997) 296-303
27. Rosen A., Wallenstein S., and McGovern M.M. Attitudes of pediatric residents toward ethical issues associated with genetic testing in children. Pediatrics 110 2 Pt 1 (2002) 360-363
28. Demmer L.A., O'Neill M.J., Roberts A.E., and Clay M.C. Knowledge of ethical standards in genetic testing among medical students, residents, and practicing physicians. JAMA 284 20 (2000) 2595-2596
29. Plantinga L., Natowicz M.R., Kass N.E., Hull S.C., Gostin L.O., and Faden R.R. Disclosure, confidentiality, and families: experiences and attitudes of those with genetic versus nongenetic medical conditions. Am J Med Genet 119C 1 (2003) 51-59
30. Kent A. Consent and confidentiality in genetics: whose information is it anyway?. J Med Ethics 29 (2003) 116-118
31. Gostin L.O. Genetic privacy. J Law Med Ethics 23 4 (1995) 320-330
32. Richards F.H. Maturity of judgement in decision making for predictive testing for nontreatable adult-onset neurogenetic conditions: a case against predictive testing of minors. Clin Genet 70 5 (2006) 396-401
33. Press N.A., Yasui Y., Reynolds S., Durfy S.J., and Burke W. Women's interest in genetic testing for breast cancer susceptibility may be based on unrealistic expectations. Am J Med Genet 1 99 2 (2001) 99-110
34. Walter F.M., Kinmonth A.L., Hyland F., Murrell P., Marteau T.M., and Todd C. Experiences and expectations of the new genetics in relation to familial risk of breast cancer: a comparison of the views of GPs and practice nurses. Fam Pract 18 5 (2001) 491-494
35. Borry P., Fryns J.P., and Dierickx K. Predictive genetic testing in children. A clinical-ethical analysis. In: de Bouvet A., Boitte P., and Aiguier G. (Eds). Questions éthique en médicine predictive. Montrouge Editions (2006), John Libbey Eurotext 89-98
36. Duncan R.E., Savulescu J., Gillam L., Williamson R., and Delatycki M.B. An international survey of predictive genetic testing in children for adult onset conditions. Genet Med 7 6 (2005) 390-396
37. Geller G., Bernhardt A., Doksum T., Helzlsouer K., Wilcox P., and Holtzman N. Decision-making about breast cancer susceptibility testing: How similar are the attitudes of physicians, nurse practitioners, and at-risk women?. J Clin Oncol 16 8 (1998) 2868-2876
38. Yumuk P., Gumus M., Ekenel M., Basaran G., Aliustaoglu M., Topal A., and Turhal N. Attitude toward genetic testing for cancer risk in Istanbul. Genet Test 8 2 (2004) 169-173