메뉴 건너뛰기




Volumn 96, Issue 12, 2007, Pages 3478-3484

Disposition of the cholesterol absorption inhibitor ezetimibe in mdr1a/b (-/-) Mice

Author keywords

Absorption; Disposition; Drug transport; Ezetimibe; mdr1; P glycoprotein

Indexed keywords

ANTILIPEMIC AGENT; EZETIMIBE; GLUCURONIDE; GLYCOPROTEIN P;

EID: 35649019126     PISSN: 00223549     EISSN: 15206017     Source Type: Journal    
DOI: 10.1002/jps.20996     Document Type: Article
Times cited : (9)

References (20)
  • 2
    • 0037111924 scopus 로고    scopus 로고
    • Efficacy and safety of a potent new selective cholesterol absorption inhibitor, Ezetimibe, in patients with primary hypercholesterolemia
    • Dujovne CA, Ettinger MP, Mcneer JF, Lipka LJ, LeBeaut AP, Suresh R, Yang B, Veltri EP. 2002. Efficacy and safety of a potent new selective cholesterol absorption inhibitor, Ezetimibe, in patients with primary hypercholesterolemia. Am J Cardiol 90:1092-1097.
    • (2002) Am J Cardiol , vol.90 , pp. 1092-1097
    • Dujovne, C.A.1    Ettinger, M.P.2    Mcneer, J.F.3    Lipka, L.J.4    LeBeaut, A.P.5    Suresh, R.6    Yang, B.7    Veltri, E.P.8
  • 7
    • 4544247030 scopus 로고    scopus 로고
    • Assessment of a multiple-dose drug interaction between ezetimibe, a novel selective cholesterol absorption inhibitor and gemfibrozil
    • Reyderman L, Kosoglou T, Statkevich P, Pember L, Boutros T, Maxwell SE. 2004. Assessment of a multiple-dose drug interaction between ezetimibe, a novel selective cholesterol absorption inhibitor and gemfibrozil. Int J Clin Pharmacol Ther 42:512-518.
    • (2004) Int J Clin Pharmacol Ther , vol.42 , pp. 512-518
    • Reyderman, L.1    Kosoglou, T.2    Statkevich, P.3    Pember, L.4    Boutros, T.5    Maxwell, S.E.6
  • 8
    • 33751103450 scopus 로고    scopus 로고
    • Disposition and sterol-lowering effect of ezetimibe are influenced by single-dose coadministration of rifampin, an inhibitor of multidrug transport proteins
    • Oswald S, Giessmann T, Luetjohann D, Wegner D, Rosskopf D, Weitschies W, Siegmund W. 2006. Disposition and sterol-lowering effect of ezetimibe are influenced by single-dose coadministration of rifampin, an inhibitor of multidrug transport proteins. Clin Pharmacol Ther 80:477-485.
    • (2006) Clin Pharmacol Ther , vol.80 , pp. 477-485
    • Oswald, S.1    Giessmann, T.2    Luetjohann, D.3    Wegner, D.4    Rosskopf, D.5    Weitschies, W.6    Siegmund, W.7
  • 9
    • 33747606815 scopus 로고    scopus 로고
    • Disposition and sterol-lowering effect of ezetimibe in multidrug resistance-associated protein 2-deficient rats
    • Oswald S, Westrup S, Grube M, Kroemer HK, Weitschies W, Siegmund W. 2006. Disposition and sterol-lowering effect of ezetimibe in multidrug resistance-associated protein 2-deficient rats. J Pharmacol Exp Ther 318:1293-1299.
    • (2006) J Pharmacol Exp Ther , vol.318 , pp. 1293-1299
    • Oswald, S.1    Westrup, S.2    Grube, M.3    Kroemer, H.K.4    Weitschies, W.5    Siegmund, W.6
  • 10
    • 0032518290 scopus 로고    scopus 로고
    • The drug transporter P-glycoprotein limits oral absorption and brain entry of HIV-1 protease inhibitors
    • Kim RB, Fromm MF, Wandel C, Leake B, Wood AJ, Roden DM, Wilkinson GR. 1998. The drug transporter P-glycoprotein limits oral absorption and brain entry of HIV-1 protease inhibitors. J Clin Invest 101:289-294.
    • (1998) J Clin Invest , vol.101 , pp. 289-294
    • Kim, R.B.1    Fromm, M.F.2    Wandel, C.3    Leake, B.4    Wood, A.J.5    Roden, D.M.6    Wilkinson, G.R.7
  • 11
    • 0030781139 scopus 로고    scopus 로고
    • Full blockade of intestinal P-glycoprotein and extensive inhibition of blood-brain barrier P-glycoprotein by oral treatment of mice with P SC833
    • Mayer U, Wagenaar E, Dorobek B, Beijnen JH, Borst P, Schinkel AH. 1997. Full blockade of intestinal P-glycoprotein and extensive inhibition of blood-brain barrier P-glycoprotein by oral treatment of mice with P SC833. J Clin Invest 100:2430-2436.
    • (1997) J Clin Invest , vol.100 , pp. 2430-2436
    • Mayer, U.1    Wagenaar, E.2    Dorobek, B.3    Beijnen, J.H.4    Borst, P.5    Schinkel, A.H.6
  • 12
    • 0028825399 scopus 로고
    • Absence of the mdr1a P-glycoprotein in mice affects tissue distribution and pharmacokinetics of dexamethasone, digoxin, and cyclosporin A
    • Schinkel AH, Wagenaar E, van Deemter L, Mol CA, Borst P. 1995. Absence of the mdr1a P-glycoprotein in mice affects tissue distribution and pharmacokinetics of dexamethasone, digoxin, and cyclosporin A. J Clin Invest 96:1698-1705.
    • (1995) J Clin Invest , vol.96 , pp. 1698-1705
    • Schinkel, A.H.1    Wagenaar, E.2    van Deemter, L.3    Mol, C.A.4    Borst, P.5
  • 14
    • 29244481684 scopus 로고    scopus 로고
    • A LC-MS/MS method to quantify the novel cholesterol lowering drug ezetimibe in human serum, urine and feces in healthy subjects genotyped for SLCO1 B1
    • Oswald S, Scheuch E, Cascorbi I, Siegmund W. 2006. A LC-MS/MS method to quantify the novel cholesterol lowering drug ezetimibe in human serum, urine and feces in healthy subjects genotyped for SLCO1 B1. J Chromatogr B Analyt Technol Biomed Life Sci 830:143-150.
    • (2006) J Chromatogr B Analyt Technol Biomed Life Sci , vol.830 , pp. 143-150
    • Oswald, S.1    Scheuch, E.2    Cascorbi, I.3    Siegmund, W.4
  • 15
    • 0032705762 scopus 로고    scopus 로고
    • Physiologically based pharmacokinetics of digoxin in mdr1a knockout mice
    • Kawahara M, Sakata A, Miyashita T, Tamai I, Tsuji A. 1999. Physiologically based pharmacokinetics of digoxin in mdr1a knockout mice. J Pharm Sci 88:1281-1287.
    • (1999) J Pharm Sci , vol.88 , pp. 1281-1287
    • Kawahara, M.1    Sakata, A.2    Miyashita, T.3    Tamai, I.4    Tsuji, A.5
  • 17
    • 0036175308 scopus 로고    scopus 로고
    • Pharmacokinetic role of P-glycoprotein in oral bioavailability and intestinal secretion of grepafloxacin in vivo
    • Yamaguchi H, Yano I, Saito H, Inui K. 2002. Pharmacokinetic role of P-glycoprotein in oral bioavailability and intestinal secretion of grepafloxacin in vivo. J Pharmacol Exp Ther 300:1063-1069.
    • (2002) J Pharmacol Exp Ther , vol.300 , pp. 1063-1069
    • Yamaguchi, H.1    Yano, I.2    Saito, H.3    Inui, K.4
  • 19
    • 24944483081 scopus 로고    scopus 로고
    • Bile acid transport in sister of P-glycoprotein (ABCB11) knockout mice
    • Lam P, Wang R, Ling V. 2005. Bile acid transport in sister of P-glycoprotein (ABCB11) knockout mice. Biochemistry 44:12598-12605.
    • (2005) Biochemistry , vol.44 , pp. 12598-12605
    • Lam, P.1    Wang, R.2    Ling, V.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.