메뉴 건너뛰기




Volumn 263, Issue 1-2, 2007, Pages 70-74

Is brain lactate increased in Huntington's disease?

Author keywords

Energy metabolism; Huntington's disease; Lactate; Magnetic resonance spectroscopy; Mitochondrial function

Indexed keywords

CREATININE; LACTIC ACID; N ACETYLASPARTIC ACID;

EID: 35649013819     PISSN: 0022510X     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.jns.2007.05.035     Document Type: Article
Times cited : (32)

References (23)
  • 2
    • 0027480960 scopus 로고
    • A novel gene containing a trinucleotide repeat that is expanded and unstable on Huntington's disease chromosomes
    • Huntington's Disease Collaborative Research Group. A novel gene containing a trinucleotide repeat that is expanded and unstable on Huntington's disease chromosomes. Cell 72 (1993) 971-983
    • (1993) Cell , vol.72 , pp. 971-983
    • Huntington's Disease Collaborative Research Group1
  • 3
    • 0021883670 scopus 로고
    • Regional mitochondrial respiratory activity in Huntington's disease brain
    • Brennan W.A., Bird E.D., and Aprille J.R. Regional mitochondrial respiratory activity in Huntington's disease brain. J Neurochem 44 (1985) 1948-1950
    • (1985) J Neurochem , vol.44 , pp. 1948-1950
    • Brennan, W.A.1    Bird, E.D.2    Aprille, J.R.3
  • 5
    • 0025087726 scopus 로고
    • Evidence for a defect in NADH: ubiquinone oxidoreductase (complex I) in Huntington's disease
    • Parker W.D., Boyson S.J., Luder A.S., and Parks J.K. Evidence for a defect in NADH: ubiquinone oxidoreductase (complex I) in Huntington's disease. Neurology 40 (1990) 1231-1234
    • (1990) Neurology , vol.40 , pp. 1231-1234
    • Parker, W.D.1    Boyson, S.J.2    Luder, A.S.3    Parks, J.K.4
  • 6
    • 0000298671 scopus 로고
    • 3-nitropropionic acid decreases cellular energy levels and causes neuronal degeneration in cortical explants
    • Ludolph A.C., Seelig M.O., Ludolph A., et al. 3-nitropropionic acid decreases cellular energy levels and causes neuronal degeneration in cortical explants. Neurodegeneration 1 (1992) 21-28
    • (1992) Neurodegeneration , vol.1 , pp. 21-28
    • Ludolph, A.C.1    Seelig, M.O.2    Ludolph, A.3
  • 7
    • 0027204154 scopus 로고
    • Age-dependent striatal excitotoxic lesions produced by the endogenous mitochondrial inhibitor malonate
    • Beal M.F., Brouillet E., Jenkins B., Henshaw R., Rosen B., and Hyman B.T. Age-dependent striatal excitotoxic lesions produced by the endogenous mitochondrial inhibitor malonate. J Neurochem 61 (1993) 1147-1150
    • (1993) J Neurochem , vol.61 , pp. 1147-1150
    • Beal, M.F.1    Brouillet, E.2    Jenkins, B.3    Henshaw, R.4    Rosen, B.5    Hyman, B.T.6
  • 8
    • 0026347825 scopus 로고
    • Aminooxyacetic acid results in excitotoxin lesions by a novel indirect mechanism
    • Beal M.F., Swartz K.J., Hyman B.T., et al. Aminooxyacetic acid results in excitotoxin lesions by a novel indirect mechanism. J Neurochem 57 (1991) 1068-1073
    • (1991) J Neurochem , vol.57 , pp. 1068-1073
    • Beal, M.F.1    Swartz, K.J.2    Hyman, B.T.3
  • 9
    • 0027741301 scopus 로고
    • Evidence for impairment of energy metabolism in vivo in Huntington's disease using localized 1H NMR spectroscopy
    • Jenkins B.G., Koroshetz W.J., Beal M.F., and Rosen B.R. Evidence for impairment of energy metabolism in vivo in Huntington's disease using localized 1H NMR spectroscopy. Neurology 43 (1993) 2689-2695
    • (1993) Neurology , vol.43 , pp. 2689-2695
    • Jenkins, B.G.1    Koroshetz, W.J.2    Beal, M.F.3    Rosen, B.R.4
  • 10
    • 0031900412 scopus 로고    scopus 로고
    • Quantitative proton-decoupled 31P MRS and 1H MRS in the evaluation of Huntington's and Parkinson's diseases
    • Hoang T.Q., Bluml S., Dubowitz D.J., et al. Quantitative proton-decoupled 31P MRS and 1H MRS in the evaluation of Huntington's and Parkinson's diseases. Neurology 50 (1998) 1033-1040
    • (1998) Neurology , vol.50 , pp. 1033-1040
    • Hoang, T.Q.1    Bluml, S.2    Dubowitz, D.J.3
  • 11
    • 85009332113 scopus 로고    scopus 로고
    • The Unified Huntington's Disease Rating Scale: reliability and consistency
    • Huntington Study Group. The Unified Huntington's Disease Rating Scale: reliability and consistency. Mov Disord 11 (1996) 136-142
    • (1996) Mov Disord , vol.11 , pp. 136-142
    • Huntington Study Group1
  • 12
    • 0018303366 scopus 로고
    • Huntington's disease: clinical care and evaluation
    • Shoulson I., and Fahn S. Huntington's disease: clinical care and evaluation. Neurology 29 (1979) 1-3
    • (1979) Neurology , vol.29 , pp. 1-3
    • Shoulson, I.1    Fahn, S.2
  • 13
    • 0027200329 scopus 로고
    • Automatic, localized in vivo adjustment of all first- and second-order shim coils
    • Gruetter R. Automatic, localized in vivo adjustment of all first- and second-order shim coils. Magn Reson Med 29 (1993) 804-811
    • (1993) Magn Reson Med , vol.29 , pp. 804-811
    • Gruetter, R.1
  • 14
    • 0000068844 scopus 로고
    • Critical factors in design of sensitive high-resolution nuclear magnetic-resonance spectrometers
    • Hoult D.I., and Richards R.E. Critical factors in design of sensitive high-resolution nuclear magnetic-resonance spectrometers. Proc R Soc Lond A 344 (1975) 311-340
    • (1975) Proc R Soc Lond A , vol.344 , pp. 311-340
    • Hoult, D.I.1    Richards, R.E.2
  • 15
    • 35649009988 scopus 로고    scopus 로고
    • Segmentation of brain from a PRESS localised single volume using double inversion recovery for simultaneous T1 nulling
    • Hanstock C.C., and Allen P.S. Segmentation of brain from a PRESS localised single volume using double inversion recovery for simultaneous T1 nulling. Proceedings of the Society of Magnetic Resonance in Medicine (2000) 1964
    • (2000) Proceedings of the Society of Magnetic Resonance in Medicine , pp. 1964
    • Hanstock, C.C.1    Allen, P.S.2
  • 16
    • 0029034511 scopus 로고
    • Widespread expression of the Huntington's disease gene (IT-15) protein product
    • Sharp N.H., Love S.J., Schilling G., et al. Widespread expression of the Huntington's disease gene (IT-15) protein product. Neuron 14 (1995) 1065-1074
    • (1995) Neuron , vol.14 , pp. 1065-1074
    • Sharp, N.H.1    Love, S.J.2    Schilling, G.3
  • 17
    • 0030771894 scopus 로고    scopus 로고
    • Huntington localization in brains of normal and Huntington's disease patients
    • Sapp E., Schwarz C., Chae K., et al. Huntington localization in brains of normal and Huntington's disease patients. Ann Neurol 42 (1997) 604-612
    • (1997) Ann Neurol , vol.42 , pp. 604-612
    • Sapp, E.1    Schwarz, C.2    Chae, K.3
  • 18
    • 0031930949 scopus 로고    scopus 로고
    • Increasing striatal iron content associated with normal aging
    • Martin W.R.W., Ye F.Q., and Allen P.S. Increasing striatal iron content associated with normal aging. Mov Disord 13 (1998) 281-286
    • (1998) Mov Disord , vol.13 , pp. 281-286
    • Martin, W.R.W.1    Ye, F.Q.2    Allen, P.S.3
  • 19
    • 0342368660 scopus 로고    scopus 로고
    • Proton magnetic resonance spectroscopy of cerebrospinal fluid in neurodegenerative disease: indication of glial energy impairment in Huntington chorea, but not Parkinson disease
    • Garseth M., Sonnewald U., White L.R., et al. Proton magnetic resonance spectroscopy of cerebrospinal fluid in neurodegenerative disease: indication of glial energy impairment in Huntington chorea, but not Parkinson disease. J Neurosci Res 60 (2000) 779-782
    • (2000) J Neurosci Res , vol.60 , pp. 779-782
    • Garseth, M.1    Sonnewald, U.2    White, L.R.3
  • 20
    • 0027272037 scopus 로고
    • CSF and serum metabolic profile of patients with Huntington's chorea: A study by high resolution proton NMR spectroscopy and HPLC
    • Nicoli F., Vion-Dury J., Maloteaux J.M., et al. CSF and serum metabolic profile of patients with Huntington's chorea: A study by high resolution proton NMR spectroscopy and HPLC. Neurosci Lett 154 (1993) 47-51
    • (1993) Neurosci Lett , vol.154 , pp. 47-51
    • Nicoli, F.1    Vion-Dury, J.2    Maloteaux, J.M.3
  • 22
    • 0031035154 scopus 로고    scopus 로고
    • Decreased N-acetyl-aspartate/choline ratio and increased lactate in the frontal lobe of patients with Huntington's disease: a proton magnetic resonance spectroscopy study
    • Harms L., Meierkord H., Timm G., Pfeiffer L., and Ludolph A.C. Decreased N-acetyl-aspartate/choline ratio and increased lactate in the frontal lobe of patients with Huntington's disease: a proton magnetic resonance spectroscopy study. J Neurol Neurosurg Psychiatry 62 (1997) 27-30
    • (1997) J Neurol Neurosurg Psychiatry , vol.62 , pp. 27-30
    • Harms, L.1    Meierkord, H.2    Timm, G.3    Pfeiffer, L.4    Ludolph, A.C.5
  • 23
    • 1542348209 scopus 로고    scopus 로고
    • The energetics of Huntington's disease
    • Browne S.E., and Beal M.F. The energetics of Huntington's disease. Neurochem Res 29 (2004) 531-546
    • (2004) Neurochem Res , vol.29 , pp. 531-546
    • Browne, S.E.1    Beal, M.F.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.