Cardiac fas receptor-dependent apoptotic pathway in obese zucker rats

Obesity

Volumn 15, Issue 10, 2007, Pages 2407-2415

  Lee, Shin Da ^a   Tzang, Bor Show ^b   Kuo, Wei Wen ^a   Lin, Yueh Min ^c   Yang, Ai Lan ^d,e   Chen, Szu Hua ^a,f   Tsai, Fuu Jen ^a   Wu, Fong Li ^g   Lu, Min Chi ^a   Huang, Chih Yang ^a,f  

^a CHINA MEDICAL UNIVERSITY   (Taiwan)

^b CHUNG SHAN MEDICAL UNIVERSITY   (Taiwan)

^c CHANGHUA CHRISTIAN HOSPITAL   (Taiwan)

^d NATIONAL CHENG KUNG UNIVERSITY   (Taiwan)

^e TUNGHAI UNIVERSITY   (Taiwan)

^f CHINA MEDICAL UNIVERSITY HOSPITAL   (Taiwan)

^g CHUNG SHAN MEDICAL UNIVERSITY HOSPITAL   (Taiwan)

Author keywords

Animal models; Apoptosis; Cardiomyopathy; Zucker rats

Indexed keywords

CASPASE 3; CASPASE 8; DEATH RECEPTOR; FAS ANTIGEN;

ANIMAL; APOPTOSIS; ARTICLE; BODY WEIGHT; CARDIOMYOPATHY; DRUG POTENTIATION; FIBROSIS; HEART MUSCLE; MALE; METABOLISM; OBESITY; ORGAN SIZE; PATHOLOGY; RAT; ZUCKER RAT;

ANIMALS; ANTIGENS, CD95; APOPTOSIS; BODY WEIGHT; CARDIOMYOPATHIES; CASPASE 3; CASPASE 8; FIBROSIS; MALE; MYOCARDIUM; OBESITY; ORGAN SIZE; RATS; RATS, ZUCKER; RECEPTORS, DEATH DOMAIN;

ANIMALIA; RATTUS;

EID: 35648998932     PISSN: 19307381     EISSN: 1930739X     Source Type: Journal    
DOI: 10.1038/oby.2007.286     Document Type: Article

References (32)

1. Lee SD, Magalang UJ, Krasney JA, Farkas GA. Opioidergic modulation of ventilatory response to sustained hypoxia in obese Zucker rats. Obes Res. 2001;9:407-13.
2. Lee SD, Nakano H, Farkas GA. NMDA receptor-mediated modulation of ventilation in obese Zucker rats, Int J Obes Relat Metab Disord. 2001;25:997-1004.
3. Lee SD, Nakano H, Farkas GA. Adenosinergic modulation of ventilation in obese Zucker rats. Obes Res. 2005;13:545-55.
4. Farkas GA, Schlenker EH. Pulmonary ventilation and mechanics in morbidly obese Zucker rats. Am J Respir Crit Care Med. 1994;150:356-62.
5. Nakano H, Magalang UJ, Lee SD, Krasney JA, Farkas GA. Serotonergic modulation of ventilation and upper airway stability in obese Zucker rats. Am J Respir Crit Care Med. 2001;163:1191-7.
6. Alonso-Galicia M, Brands MW, Zappe DH, Hall JE. Hypertension in obese Zucker rats: role of angiotensin II and adrenergic activity. Hypertension. 1996;28:1047-54.
7. Fredersdorf S, Thumann C, Ulucan C, et al. Myocardial hypertrophy and enhanced left ventricular contractility in Zucker diabetic fatty rats. Cardiovasc Pathol. 2004;13:11-9.
8. Lee SD, Nakano H, Farkas GA. GABAergic modulation of ventilation and peak oxygen consumption in obese Zucker rats. J Appl Physiol. 2001;90:1707-13.
9. Lee SD, Nakano H, Gosselin LE, et al. Endogenous opioids modulate ventilation and peak oxygen consumption in obese Zucker rats. Am J Respir Crit Care Med. 2000;162:1009-15.
10. Alpert MA. Obesity cardiomyopathy: pathophysiology and evolution of me clinical syndrome. Am J Med Sci. 2001;321:225-36.
11. Massie BM. Obesity and heart failure: risk factor or mechanism? N Engl J Med. 2002;347:358-9.
12. Clark K. Obesity and the risk of heart failure. J Insur Med. 2003;35:59-60.
13. Coviello JS, Nystrom KV. Obesity and heart failure. J Cardiovasc Nurs. 2003;18:360-6, quiz 367-8.
14. Haunstetter A, Izumo S. Apoptosis: basic mechanisms and implications for cardiovascular disease. Circ Res. 1998;82:1111-29.
15. Biondi-Zoccai GG, Abbate A, Vasaturo F, et al. Increased apoptosis in remote non-infarcted myocardium in multivessel coronary disease. Int J Cardiol. 2004;94:105-10.
16. Narula J, Pandey P, Arbustini E, et al. Apoptosis in heart failure: release of cytochrome c from mitochondria and activation of caspase-3 in human cardiomyopathy. Proc Natl Acad Sci USA. 1999;96:8144-9.
17. Bishopric NH, Andreka P, Slepak T, Webster KA. Molecular mechanisms of apoptosis in the cardiac myocyte. Curr Opin Pharmacol. 2001;1:141-50.
18. Lee SD, Kuo WW, Lin JA, et al. Effects of long-term intermittent hypoxia on mitochondrial and Fas death receptor dependent apoptotic pathways in rat hearts. Int J Cardiol. 2007;116:348-56.
19. Reddy MB, Clark L. Iron, oxidative stress, and disease risk. Nutr Rev. 2004;62:120-4.
20. Oudit GY, Trivieri MG, Khaper N, et al. Taurine supplementation reduces oxidative stress and improves cardiovascular function in an iron-overload murine model. Circulation. 2004;109:1877-85.
21. Sorescu D, Griendling KK. Reactive oxygen species, mitochondria, and NAD(P)H oxidases in the development and progression of heart failure. Congest Heart Fail. 2002;8:132-40.
22. Kim S, Iwao H. Molecular and cellular mechanisms of angiotensin II-mediated cardiovascular and renal diseases. Pharmacol Rev. 2000;52:11-34.
23. National Institutes of Health. Guide for the Care and Use of Laboratory Animals. Washington, DC: National Academy Press; 1996.
24. Alexander JK. Obesity and the heart. Heart Dis Stroke. 1993;2:317-21.
25. Lee SD, Chu CH, Huang EJ, et al. Roles of insulinlikegrowth factor II in cardiomyoblast apoptosis and in hypertensive rat heart with abdominal aorta ligation. Am J Physiol Endocrinol Metab. 2006;291:E306-14.
26. Lee SD, Kuo WW, Wu CH, et al. Effects of short- and long-term hypobaric hypoxia on Bcl2 family in rat heart. Int J Cardiol. 2006;108:376-84.
27. D'Armiento J. Matrix metalloproteinase disruption of the extracellular matrix and cardiac dysfunction. Trends Cardiovasc Med. 2002;12:97-101.
28. Anversa P, Nadal-Ginard B. Myocyte renewal and ventricular remodelling. Nature. 2002;415:240-3.
29. Zhou YT, Grayburn P, Karim A, et al. Lipotoxic heart disease in obese rats: implications for human obesity. Proc Natl Acad Sci USA. 2000;97:1784-9.
30. Unger RH, Orci L. Diseases of liporegulation: new perspective on obesity and related disorders. FASEB J. 2001;15:312-21.
31. Barouch LA, Gao D, Chen L, et al. Cardiac myocyte apoptosis is associated with increased DNA damage and decreased survival in murine models of obesity. Circ Res. 2006;98:119-24.
32. Kenchaiah S, Evans JC, Levy D, et al. Obesity and the risk of heart failure. N Engl J Med. 2002;347:305-13.