Delivery of adenoviral vectors to the prostate for gene therapy

Cancer Gene Therapy

Volumn 6, Issue 1, 1999, Pages 64-72

  Lu, Yi ^a,b   Carraher, John ^a   Zhang, Yu ^a   Armstrong, Jianling ^a   Lerner, Jody ^a   Rogers, William P ^a   Steiner, Mitchell S ^a  

^a UNIVERSITY OF TENNESSEE HEALTH SCIENCE CENTER   (United States)

^b UNIVERSITY OF TENNESSEE COLLEGE OF MEDICINE   (United States)

Author keywords

Adenovirus; Gene therapy; Prostate; galactosidase (lacZ)

Indexed keywords

5 BROMO 4 CHLORO 3 INDOLYL BETA GALACTOSIDE; 5-BROMO-4-CHLORO-3-INDOLYL BETA-GALACTOSIDE; BETA GALACTOSIDASE; GALACTOSIDE; INDOLE DERIVATIVE;

ADENOVIRUS; ANIMAL; ARTICLE; COMPARATIVE STUDY; DOG; GENE THERAPY; GENE VECTOR; GENETICS; MALE; METABOLISM; METHODOLOGY; PROSTATE; PROSTATE TUMOR; SOUTHERN BLOTTING; TISSUE DISTRIBUTION;

ADENOVIRIDAE; ANIMALS; BETA-GALACTOSIDASE; BLOTTING, SOUTHERN; DOGS; GALACTOSIDES; GENE THERAPY; GENETIC VECTORS; INDOLES; MALE; PROSTATE; PROSTATIC NEOPLASMS; TISSUE DISTRIBUTION;

EID: 0032618042     PISSN: 09291903     EISSN: None     Source Type: Journal    
DOI: 10.1038/sj.cgt.7700011     Document Type: Article

References (24)

1. Parker SL, Tong T, Bolden S, Wingo PA. Cancer statistics, 1997. CA Cancer J Clin. 1997;47:5-27.
2. Walsh PC. Prostate cancer kills: strategy to reduce deaths. Urology. 1994;44:463-466.
3. Mitchell MF, Hamada K, Sastry KJ, et al. Transgene expression in the rhesus cervix mediated by an adenovirus expressing β-galactosidase. Am J Obstet Gynecol. 1996;174: 1094-1101.
4. Hashimoto M, Aruga J, Hosoya Y, et al. A neural cell-type-specific expression system using recombinant adenovirus vectors. Hum Gene Ther. 1996;7:149-158.
5. Quantin B, Perricaudet LD, Tajbakhsh S, Mandel J-L. Adenovirus as an expression vector in muscle cells in vivo. Proc Natl Acad Sci USA. 1992;89:2581-2584.
6. Arbuthnot PB, Bralet M-P, Le Jossic C, et al. In vitro and in vivo hepatoma cell-specific expression of a gene transferred with an adenoviral vector. Hum Gene Ther. 1996;7: 1503-1514.
7. Mastrangeli A, Danel C, Rosenfeld M, et al. Diversity of airway epithelial cell targets for in vivo recombinant adenovirus-mediated gene transfer. J Clin Invest. 1993;91: 225-234.
8. Byrnes AP, Rusby JE, Wood MJA, Charlton HM. Adenovirus gene transfer causes inflammation in the brain. Neuroscience. 1995;66:1015-1024.
9. Stratford-Perricaudet LD, Makeh I, Perricaudet M, Briand P. Widespread long-term gene transfer to mouse skeletal muscles and heart. J Clin Invest. 1992;90:626-630.
10. Tang D-C, Johnson SA, Carbone DP. Butyrate-inducible and tumor-restricted gene expression by adenovirus vectors. Cancer Gene Ther. 1994;1:15-20.
11. Eastham JA, Hall SJ, Sehgal I, et al. In vivo gene therapy with p53 or p21 adenovirus for prostate cancer. Cancer Res. 1995;55:5151-5155.
12. Ko SC, Gotoh A, Thalmann GN, et al. Molecular therapy with recombinant p53 adenovirus in an androgen-independent, metastatic human prostate cancer model. Hum Gene Ther. 1996;7:1683-1691.
13. Gotoh A, Kao C, Ko SC, Hamada K, Liu TJ, Chung LW. Cytotoxic effects of recombinant adenovirus p53 and cell cycle regulator genes (p21 WAF1/CIP1 and p16CDKN4) in human prostate cancers. J Urol. 1997;158:636-641.
14. Fire A, Harrison S, Dixon D. A modular set of lacZ fusion vectors for studying gene expression in Caenorhabditis elegans. Gene. 1990;93:189-198.
15. McGrory WJ, Bautista DS, Graham FL. A simple technique for the rescue of early region 1 mutations into infectious human adenovirus type 5. Virology. 1988;163: 614-617.
16. Kingston RE. Introduction of DNA into mammalian cell. In: Ausubel FM, Brent R, Kingston RE, et al, eds. Current Protocols in Molecular Biology. 2nd Ed. New York: John Wiley and Sons; 1993:9.1.4-9.1.9.
17. Graham FL, Prevec L. Manipulation of adenovirus vectors. In: Murray EJ, ed. Methods in Molecular Biology. Gene transfer and expression protocols; vol. 7. Clifton, NJ: The Human Press; 1991:109-128.
18. Eastham JA, Chen S-H, Sehgal I, et al. Prostate cancer gene therapy: herpes simplex virus thymidine kinase gene transduction followed by ganciclovir in mouse and human prostate cancer models. Hum Gene Ther. 1996;7:515-523.
19. Sambrook J, Fritsch E, Maniatis T. Analysis of genomic DNA by Southern hybridization. In: Sambrook J, Fritsch E, Maniatis T, eds. Molecular Cloning. Plainview, NY: Cold Spring Harbor Laboratory Press; 1989:9.34-9.45.
20. Siegfried W. Perspectives in gene therapy with recombinant adenoviruses. Exp Clin Endocrinol. 1993;101:7-11.
21. Culver KW. Methods for gene transfer and repair. In: Culver KW, ed. Gene Therapy: A Primer for Physicians. 2nd Ed. Larchmont, NY: Mary Ann Liebert; 1996:19-37.
22. Wood M, Perrotte P, Onishi E, et al. Biodistribution of an adenoviral vector after intravesical administration in a mouse model. Cancer Gene Ther. 1997;4:S34.
23. Herz J, Gerard RD. Adenovirus-mediated transfer of low density lipoprotein receptor gene acutely accelerates cholesterol clearance in normal mice. Proc Natl Acad Sci USA. 1993;90:2812-2816.
24. Wilson DL, Timmons TM, Burt K, et al. Characterization of adenoviral biodistribution and dissemination: from preclinical models to patients. Cancer Gene Ther. 1997;4:S22.