Association of a 27-bp repeat polymorphism in intron 4 of endothelial constitutive nitric oxide synthase gene with myocardial infarction in Tunisian patients

Clinical Chemistry and Laboratory Medicine

Volumn 45, Issue 11, 2007, Pages 1476-1480

  Jemaa, Riadh ^a   Kallel, Amani ^a   Ben Ali, Samir ^a   Omar, Souheil ^a   Chabrak, Sonia ^a   Elasmi, Monia ^a   Haj Taieb, Sameh ^a   Sanhaji, Haïfa ^a   Feki, Moncef ^a   Mechmeche, Rachid ^a   Kaabachi, Naziha ^a  

^a LA RABTA HOSPITAL   (Tunisia)

Author keywords

Endothelial nitric oxide synthase gene; Myocardial infarction; Polymorphism

Indexed keywords

NITRIC OXIDE SYNTHASE;

ADULT; ARTICLE; BASE PAIRING; CONTROLLED STUDY; DNA POLYMORPHISM; FEMALE; GENE FREQUENCY; GENOTYPE; HEART INFARCTION; HUMAN; INTRON; MAJOR CLINICAL STUDY; MALE; POLYMERASE CHAIN REACTION; PRIORITY JOURNAL; TANDEM REPEAT;

ALLELES; BASE SEQUENCE; DNA PRIMERS; GENE FREQUENCY; HUMANS; INTRONS; MALE; MIDDLE AGED; MYOCARDIAL INFARCTION; NITRIC OXIDE SYNTHASE TYPE III; POLYMERASE CHAIN REACTION; POLYMORPHISM, GENETIC; TUNISIA;

EID: 35648996560     PISSN: 14346621     EISSN: 14374331     Source Type: Journal    
DOI: 10.1515/CCLM.2007.312     Document Type: Article

References (39)

1. Marenberg ME, Risch N, Berkman LF, Floderus B, de Faire U. Genetic susceptibility to death from coronary heart disease in a study of twins. N Engl J Med 1994;14:1041-6.
2. Nora JJ, Lortscher RH, Spangler RD, Nora AH, Kimberling WJ. Genetic-epidemiologic study of early onset ischemic heart disease. Circulation 1980;61:503-8.
3. Moncada S, Higgs A. The L-arginine-nitric oxide pathway. N Engl J Med 1993;329:2002-12.
4. Andrew PJ, Mayer B. Enzymatic function of nitric oxide synthase. Cardiovasc Res 1999;43:521-31.
5. Cayatte AJ, Palacino JJ, Horten K, Cohen RA. Chronic inhibition of nitric oxide production accelerates neointima formation and impairs endothelial function in hypercholesterolemic rabbits. Arterioscler Thromb 1994;14:753-9.
6. Marsden P, Heng H, Scherer S, Stewart R, Hall A, Shi XM. Structure and chromosomal localization of the human constitutive endothelial nitric oxide synthase gene. J Biol Chem 1993;268:17478-88.
7. Alvarez R, Gonzalez P, Batalla A, Reguero JR, Iglesias-Cubero G, Hevia S, et al. Association between the NOS3 (-786T/C) and the ACE (I/D) DNA genotypes and early coronary artery disease. Nitric Oxide 2001;5:343-8.
8. Wang XL, Sim AS, Badenhop RF, McGredie RM, Wilken DE. A smoking-dependent risk of coronary artery disease associated with polymorphism of the endothelial nitric oxide synthase gene. Nat Med 1996;2:41-5.
9. -786→C mutation in the 5′-flanking region of the endothelial nitric oxide synthase gene is associated with coronary spam. Circulation 1999;99:2864-70.
10. Matyar S, Attila G, Acartürk E, Akpinar O, Inal T. eNOS gene intron 4a/b VNTR polymorphism is a risk factor for coronary artery disease in southern Turkey. Clin Chim Acta 2005;354:153-8.
11. Hibi K, Ishigami T, Tamura K, Mizushima S, Nyui N, Fujita T, et al. Endothelial nitric oxide synthase gene polymorphism and myocardial infarction. Hypertension 1998;32:521-6.
12. Shimasaki Y, Yasue H, Yoshimura M, Nakayama M, Kugiyama K, Ogawa H, et al. Association of the missense Glu298Asp variant of the endothelial nitric oxide synthase gene with myocardial infarction. J Am Coll Cardiol 1998;31:1506-10.
13. Markus HS, Ruigrok Y, Ali N, Powell JF. Endothelial nitric oxide synthase exon 7 polymorphism ischemic cerebrovascular disease and carotid atheroma. Stroke 1998;29:1908-11.
14. Nakayama T, Soma M, Takahashi Y, Kanmatsuze K, Esumi M. Association analysis of CA repeat polymorphism of the endothelial nitric oxide synthase gene with essential hypertension in Japanese. Clin Genet 1997;51:26-30.
15. Miyamoto Y, Saito Y, Kajiyama N, Yoshimura M, Shimasaki Y, Nakayama M, et al. Endothelial nitric oxide synthase gene is positively associated with essential hypertension. Hypertension 1998;32:3-8.
16. Sandrim VC, de Syllos RW, Lisboa HR, Tres GS, Tanus-Santos JE. Endothelial nitric oxide synthase haplotypes affect the susceptibility to hypertension in patients with type 2 diabetes mellitus. Atherosclerosis 2006;189:241-6.
17. Suryanarayana V, Rao L, Kanakavalli M, Padmalatha V, Deenadayal M, Singh L. Recurrent early pregnancy loss and endothelial nitric oxide synthase gene polymorphisms. Arch Gynecol Obstet 2006;274:119-24.
18. Krex D, Fortun S, Kuhlisch E, Schackert HK, Schackert G. The role of endothelial nitric oxide synthase (eNOS) genetic variants in European patients with intracranial aneurysms. J Cereb Blood Flow Metab 2006;26:1250-5.
19. Granath B, Taylor RR, van Bockxmeer FM, Mamotte CD. Lack of evidence for association between endothelial nitric oxide synthase gene polymorphisms and coronary artery disease in the Australian Caucasian population. J Cardiovasc Risk 2001;8:235-41.
20. Gardemann A, Lohre J, Cayci S, Katz N, Tillmanns H, Haberbosch W. The T allele of the missense Glu(298)Asp endothelial nitric oxide synthase gene polymorphism is associated with coronary heart disease in younger individuals with high atherosclerotic risk profile. Atherosclerosis 2002;160:167-75.
21. Hwang JJ, Tsai CT, Yeh HM, Chiang FT, Hsu KL, Tseng CD, et al. The 27-bp tandem repeat polymorphism in intron 4 of the endothelial nitric oxide synthase gene is not associated with coronary artery disease in a hospital-based Taiwanese population. Cardiology 2002;97:67-72.
22. World Health Organization. Physical status: the use and interpretation of anthropometry: report of a WHO expert committee. WHO Technical Report Series. Geneva: WHO, 1995;854:321-44.
23. National Institutes of Health, National Heart, Lung and Blood Institute Obesity Education Initiative. Expert panel on the identification, evaluation, and treatment of overweight and obesity in adults 98-4083. 1998;1-262.
24. Marcadet A, O'Connel P, Cohen D. Standardized Southern blot workshop techniques. In: Dupont B, editor. Histocompatibility testing. New York: Springer, 1987:587-90.
25. Rand MJ. Nitrergic transmission: nitric oxide as a mediator of non-adrenergic, non-cholinergic neuro-effector transmission. Clin Exp Pharmacol Physiol 1992;19:147-69.
26. Hingorani AD, Liang CF, Fatibene J, Lyon A, Monteith S, Parsons A, et al. A common variant of the endothelial constitutive nitric oxide synthase (Glu298→Asp) is a major risk factor for coronary artery disease in the UK. Circulation 1999;100:1515-20.
27. Ghilardi G, Biondi ML, DeMonti M, Bemini M, Turri O, Massaro F, et al. Independent risk factor for moderate to severe internal carotid artery stenosis: T786C mutation of the endothelial nitric oxide synthase gene. Clin Chem 2002;48:989-93.
28. Kunnas TA, Ilveskoski E, Niskakangas T, Laippala E, Kajander OA, Mikkelson J, et al. Association of the endothelial nitric oxide synthase gene polymorphism with risk of coronary artery disease and myocardial infarction in middle-aged men. J Mol Med 2002;80:65-9.
29. Cine N, Hatemi AC, Erginel-Unaltuna N. Association of a polymorphism of the ecNOS gene with myocardial infarction in a subgroup of Turkish MI patients. Clin Genet 2002;61:66-70.
30. Letonja M. The eNOS gene polymorphism does not have a major impact on lipid parameters and premature coronary artery disease in Caucasian women. Acta Cardiol 2004;59:618-22.
31. Milutinovic A, Hruskovicova H. The eNOS gene polymorphism does not have a major impact on lipid parameters and premature coronary artery disease in Slovene men (Caucasians). Folia Biol (Praha) 2005;51:47-9.
32. Ichihara S, Yamada Y, Fujimura T, Nakashima N, Yokota M. Association of a polymorphism of the endothelial constitutive nitric oxide synthase gene with myocardial infarction in the Japanese population. Am J Cardiol 1998;81:83-6.
33. Poirier O, Mao C, Mallet C, Nicaud V, Hermann SM, Evans A, et al. Polymorphisms of the endothelial nitric oxide synthase gene - no consistent association with myocardial infarction in the ECTIM study. Eur J Clin Invest 1999;29:284-90.
34. Tsukada T, Yokoyama K, Arai T, Takemoto F, Hara S, Yamada A, et al. Evidence of association of the ecNOS gene polymorphism with plasma NO metabolite concentrations in humans. Biochem Biophys Res Commun 1998;245:190-3.
35. Wang XL, Mahaney MC, Sim AS, Wang J, Blangero J, Almasy L, et al. Genetic contribution of the endothelial constitutive nitric oxide synthase gene to plasma nitric oxide levels. Arterioscler Thromb Vasc Biol 1997;17:3147-53.
36. Garg UC, Hassid A. Nitric oxide-generating vasodilators and 8-bromo-cyclic guanosine monophosphate inhibit mitogenesis and proliferation of cultured rat vascular smooth muscle cells. J Clin Invest 1989;83:1774-7.
37. Cooke JP, Dzau VJ. Nitric oxide synthase: role in the genesis of vascular disease. Annu Rev Med 1997;48:489-509.
38. Radomski MW, Salas E. Nitric oxide-biological mediator, modulator and factor of injury: its role in the pathogenesis of atherosclerosis. Atherosclerosis 1995;118:S69-80.
39. Wang J, Dudley D, Wang XL. Haplotype-specific effects on endothelial NO synthase promotor efficiency: modifiable by cigarette smoking. Arterioscler Thromb Vasc Biol 2002;22:e1-4.