Cinnamylindoline derivatives: Synthesis and factor Xa (FXa) inhibitory activities

Chemical and Pharmaceutical Bulletin

Volumn 55, Issue 10, 2007, Pages 1494-1504

  Noguchi, Tetsuji ^a   Tanaka, Naoki ^a   Nishimata, Toyoki ^a   Goto, Riki ^a   Hayakawa, Miho ^a   Sugidachi, Atsuhiro ^a   Ogawa, Taketoshi ^a   Asai, Fumitoshi ^a   Fujimoto, Koichi ^a  

^a DAIICHI SANKYO CO   (Japan)

Author keywords

Anticoagulant; Cinnamylindoline derivative; Factor Xa inhibitory activity

Indexed keywords

2 [5(1(ACETIMIDOYL) PIPERIDIN 4 YLOXY) 2( 2 (5 AMIDINO 2 HYDROXYPHENYL) ETHEN 1 YL) INDOLIN 1 SULFONYL] ACETIC ACID; 2 HYDROXYCINNAMYL DERIVATIVE; ACETIC ACID DERIVATIVE; BLOOD CLOTTING FACTOR 10A; CINNAMYLINDOLINE DERIVATIVE; INDOLE DERIVATIVE; TRYPSIN; UNCLASSIFIED DRUG;

ANTICOAGULATION; ARTICLE; DRUG MECHANISM; HUMAN; IN VITRO STUDY; SYNTHESIS;

ANTICOAGULANTS; CINNAMATES; FACTOR XA; HUMANS; INDOLES; INHIBITORY CONCENTRATION 50; MAGNETIC RESONANCE SPECTROSCOPY; MODELS, CHEMICAL; STRUCTURE-ACTIVITY RELATIONSHIP; TRYPSIN;

EID: 35648991936     PISSN: 00092363     EISSN: 13475223     Source Type: Journal    
DOI: 10.1248/cpb.55.1494     Document Type: Article

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