Potent achiral agonists of the ghrelin (growth hormone secretagogue) receptor. Part I: Lead identification

Bioorganic and Medicinal Chemistry Letters

Volumn 17, Issue 23, 2007, Pages 6584-6587

  Heightman, Tom D ^a   Scott, Jackie S ^a   Longley, Mark ^a   Bordas, Vincent ^a   Dean, David K ^a   Elliott, Richard ^a   Hutley, Gail ^a   Witherington, Jason ^a   Abberley, Lee ^a   Passingham, Barry ^a   Berlanga, Manuela ^a   de los Frailes, Maite ^a   Wise, Alan ^a   Powney, Ben ^a   Muir, Alison ^a   McKay, Fiona ^a   Butler, Sharon ^a   Winborn, Kim ^a   Gardner, Christopher ^a   Darton, Jill ^a   Campbell, Colin ^a   Sanger, Gareth ^a   more..

^a GLAXOSMITHKLINE   (United Kingdom)

Author keywords

Ghrelin receptor agonist; Growth hormone secretagogue

Indexed keywords

2,6 DIMETHYLPIPERAZINYL INDOLINE; CAPROMORELIN; GROWTH HORMONE RELEASING FACTOR DERIVATIVE; GROWTH HORMONE SECRETAGOGUE RECEPTOR; GROWTH HORMONE SECRETAGOGUE RECEPTOR AGONIST; HORMONE RECEPTOR STIMULATING AGENT; IBUTAMOREN; PIPERAZINE DERIVATIVE; SM 130686; SULFONAMIDE; UNCLASSIFIED DRUG;

ARTICLE; CONTROLLED STUDY; DISTRIBUTION VOLUME; DRUG BIOAVAILABILITY; DRUG HALF LIFE; DRUG STRUCTURE; DRUG SYNTHESIS; HIGH THROUGHPUT SCREENING; IN VITRO STUDY; MOLECULAR WEIGHT; NONHUMAN; PHYSICAL CHEMISTRY; RAT; STOMACH EMPTYING; STRUCTURE ACTIVITY RELATION;

ANIMALS; GASTRIC EMPTYING; HUMAN GROWTH HORMONE; HUMANS; INDOLES; RATS; RECEPTORS, GHRELIN; STEREOISOMERISM;

RATTUS;

EID: 35648975477     PISSN: 0960894X     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bmcl.2007.09.067     Document Type: Article

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