Mechanisms of chloroform-induced hepatotoxicity: Oxidative stress and mitochondrial permeability transition in freshly isolated mouse hepatocytes

Journal of Toxicology and Environmental Health - Part A: Current Issues

Volumn 70, Issue 22, 2007, Pages 1936-1945

  Burke, Angela S ^a   Redeker, Kelly ^b   Kurten, Richard C ^a   James, Laura P ^a   Hinson, Jack A ^a  

^a UNIVERSITY OF ARKANSAS FOR MEDICAL SCIENCES   (United States)

^b ARKANSAS STATE UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

3 NITROTYROSINE; 7 NITROINDAZOLE; ACETYLCYSTEINE; ALANINE AMINOTRANSFERASE; CHLOROFORM; CYCLOSPORIN A; DICHLOROFLUORESCEIN; DYE; GLUTATHIONE; JC 1; N(G) METHYLARGININE; NITRIC OXIDE SYNTHASE INHIBITOR; PEROXYNITRITE; PROPIDIUM IODIDE; UNCLASSIFIED DRUG;

ANIMAL CELL; ARTICLE; CELL DEATH; CELL ISOLATION; CONFOCAL MICROSCOPY; CONTROLLED STUDY; FEMALE; FLUORESCENCE MICROSCOPY; LIVER CELL; LIVER TOXICITY; MITOCHONDRIAL MEMBRANE; MITOCHONDRIAL PERMEABILITY; MOUSE; MOUSE STRAIN; NITRATION; NONHUMAN; OXIDATIVE STRESS; PRIORITY JOURNAL; STATISTICAL SIGNIFICANCE; WESTERN BLOTTING;

ACETYLCYSTEINE; ALANINE TRANSAMINASE; ANIMALS; ANTIOXIDANTS; CELLS, CULTURED; CHLOROFORM; CYCLOSPORINE; FEMALE; GLUTATHIONE; HEPATOCYTES; MEMBRANE POTENTIAL, MITOCHONDRIAL; MICE; MICE, INBRED STRAINS; MITOCHONDRIA, LIVER; NITRIC OXIDE SYNTHASE; OXIDATIVE STRESS; PEROXYNITROUS ACID; REACTIVE OXYGEN SPECIES; TYROSINE;

EID: 35648965759     PISSN: 15287394     EISSN: 10872620     Source Type: Journal    
DOI: 10.1080/15287390701551399     Document Type: Article

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