Structural basis of substrate-binding specificity of human arylamine N-acetyltransferases

Journal of Biological Chemistry

Volumn 282, Issue 41, 2007, Pages 30189-30197

  Wu, Hong ^a   Dombrovsky, Ludmila ^a   Tempel, Wolfram ^a   Martin, Fernando ^a   Loppnau, Peter ^a   Goodfellow, Geoffrey H ^b   Grant, Denis M ^b   Plotnikov, Alexander N ^a,b  

^a UNIVERSITY OF TORONTO   (Canada)

^b UNIVERSITY OF TORONTO   (Canada)

Author keywords

[No Author keywords available]

Indexed keywords

AMINES; AROMATIC COMPOUNDS; DRUG PRODUCTS; MAMMALS;

AROMATIC AMINE; BIOTRANSFORMATION; HUMAN ARYLAMINE N-ACETYLTRANSFERASES;

ENZYMES;

ACETANILIDE DERIVATIVE; ARYLAMINE ACETYLTRANSFERASE; COENZYME A;

ARTICLE; CONTROLLED STUDY; CRYSTAL STRUCTURE; ENZYME ACTIVE SITE; ENZYME SPECIFICITY; ENZYME STRUCTURE; ENZYME SUBSTRATE COMPLEX; GENETIC POLYMORPHISM; NONHUMAN; PREDICTION; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN PURIFICATION; SITE DIRECTED MUTAGENESIS; STRUCTURE ANALYSIS;

ACETANILIDES; AMINO ACID SEQUENCE; ARYLAMINE N-ACETYLTRANSFERASE; BINDING SITES; CRYSTALLOGRAPHY, X-RAY; HUMANS; ISOENZYMES; MOLECULAR CONFORMATION; MOLECULAR SEQUENCE DATA; MUTATION; POLYMORPHISM, GENETIC; PROTEIN BINDING; SEQUENCE HOMOLOGY, AMINO ACID; SUBSTRATE SPECIFICITY;

EID: 35648947442     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M704138200     Document Type: Article

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