FK506 induces interleukin-6 secretion from UVB irradiated cultured human keratinocytes via p38 mitogen-activated protein kinase pathway: Implication on mechanisms of tacrolimus-induced skin irritation

Journal of Dermatological Science

Volumn 48, Issue 3, 2007, Pages 225-228

  Lan, Cheng Che E ^a,b   Yu, Hsin Su ^a,b   Huang, Shu Mei ^a   Wu, Ching Shuang ^c   Chen, Gwo Shing ^a,b  

^a KAOHSIUNG MEDICAL UNIVERSITY HOSPITAL   (Taiwan)

^b KAOHSIUNG MEDICAL UNIVERSITY   (Taiwan)

^c KAOHSIUNG MEDICAL UNIVERSITY   (Taiwan)

Author keywords

FK506; IL 6; Keratinocyte; p38 MAPK

Indexed keywords

4 (4 FLUOROPHENYL) 2 (4 METHYLSULFINYLPHENYL) 5 (4 PYRIDYL)IMIDAZOLE; INTERLEUKIN 6; MITOGEN ACTIVATED PROTEIN KINASE P38; TACROLIMUS; TRANSCRIPTION FACTOR AP 1;

ATOPIC DERMATITIS; CELL CULTURE; DRUG EFFECT; DRUG MECHANISM; ENZYME LINKED IMMUNOSORBENT ASSAY; HUMAN; KERATINOCYTE; LETTER; PHOSPHORYLATION; PRIORITY JOURNAL; PROTEIN EXPRESSION; SKIN IRRITATION; ULTRAVIOLET B RADIATION; UPREGULATION; WESTERN BLOTTING;

CELL SURVIVAL; CELLS, CULTURED; DERMATITIS; DOSE-RESPONSE RELATIONSHIP, DRUG; HUMANS; IMMUNOSUPPRESSIVE AGENTS; INTERLEUKIN-6; INTERLEUKIN-8; KERATINOCYTES; P38 MITOGEN-ACTIVATED PROTEIN KINASES; PHOSPHORYLATION; TACROLIMUS; ULTRAVIOLET RAYS;

EID: 35648945805     PISSN: 09231811     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.jdermsci.2007.08.003     Document Type: Letter

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