Synthesis, in vitro inhibitory activity towards COX-2 and haemolytic activity of derivatives of Esculentoside A

Bioorganic and Medicinal Chemistry Letters

Volumn 17, Issue 23, 2007, Pages 6430-6433

  Wu, Fei ^a   Yi, Yanghua ^a   Sun, Peng ^a   Zhang, Dazhi ^a  

^a SECOND MILITARY MEDICAL UNIVERSITY   (China)

Author keywords

Anti inflammatory; Derivatives; Esculentoside A; Structure activity relationship; Synthesis

Indexed keywords

CELECOXIB; CYCLOOXYGENASE 2; ESCULENTOSIDE A; ESCULENTOSIDE A DERIVATIVE; PLANT EXTRACT; UNCLASSIFIED DRUG;

ARTICLE; CARBON NUCLEAR MAGNETIC RESONANCE; DRUG SCREENING; DRUG STRUCTURE; DRUG SYNTHESIS; ENZYME INHIBITION; HEMOLYSIS; IN VITRO STUDY; NONHUMAN; PROTON NUCLEAR MAGNETIC RESONANCE; STRUCTURE ACTIVITY RELATION;

ANIMALS; ANTI-INFLAMMATORY AGENTS, NON-STEROIDAL; CELL LINE; CYCLOOXYGENASE 2; CYCLOOXYGENASE 2 INHIBITORS; HEMOLYSIS; HUMANS; INSECTS; OLEANOLIC ACID; RABBITS; SAPONINS; STRUCTURE-ACTIVITY RELATIONSHIP;

EID: 35648938649     PISSN: 0960894X     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bmcl.2007.10.006     Document Type: Article

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