Protective effect of esculentoside A on radiation-induced dermatitis and fibrosis

International Journal of Radiation Oncology Biology Physics

Volumn 65, Issue 3, 2006, Pages 882-889

  Xiao, Zhenyu ^a   Su, Ying ^a   Yang, Shanmin ^a   Yin, Liangjie ^a   Wang, Wei ^a   Yi, Yanghua ^a   Fenton, Bruce M ^a   Zhang, Lurong ^a   Okunieff, Paul ^a  

^a UNIVERSITY OF ROCHESTER MEDICAL CENTER   (United States)

Author keywords

Anti inflammatory; Bioterror; Interleukin 1; Radioprotector

Indexed keywords

CYTOLOGY; DRUG THERAPY; IRRADIATION; MOLECULAR BIOLOGY; RADIOTHERAPY; TISSUE; TOXICITY;

ANTI-INFLAMMATORY; BIOTERROR; INTERLEUKIN-1; RADIOPROTECTOR;

DERMATITIS;

CYTOKINE; ESCULENTOSIDE A; INTERLEUKIN 1ALPHA; INTERLEUKIN 1BETA; LIPOPOLYSACCHARIDE; MONOCYTE CHEMOTACTIC PROTEIN 1; NITRIC OXIDE; SAPONIN; TRANSFORMING GROWTH FACTOR BETA1; TUMOR NECROSIS FACTOR; UNCLASSIFIED DRUG; VASCULOTROPIN;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CELL TYPE; CONTROLLED STUDY; CYTOKINE PRODUCTION; DRUG EFFECT; DRUG MECHANISM; ENZYME LINKED IMMUNOSORBENT ASSAY; EPITHELIUM CELL; FEMALE; FIBROBLAST; HINDLIMB; HUMAN; HUMAN CELL; IN VITRO STUDY; IN VIVO STUDY; IRRADIATION; MACROPHAGE; MEASUREMENT; MOLECULAR DYNAMICS; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; RADIATION DERMATITIS; RADIATION DOSE; SCORING SYSTEM; SKIN; SKIN FIBROSIS; SKIN TOXICITY; SOFT TISSUE INJURY;

ANIMALS; CELL LINE, TUMOR; CYTOKINES; DRUGS, CHINESE HERBAL; FEMALE; FIBROBLASTS; FIBROSIS; MACROPHAGES; MICE; MICE, INBRED C57BL; NITRIC OXIDE; OLEANOLIC ACID; RADIODERMATITIS; SAPONINS; SKIN; TRANSFORMING GROWTH FACTOR BETA; TRANSFORMING GROWTH FACTOR BETA1;

EID: 33646941945     PISSN: 03603016     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.ijrobp.2006.01.031     Document Type: Article

References (39)

1. Okunieff P., Cornelison T., Mester M., et al. Mechanism and modification of gastrointestinal soft tissue response to radiation. Role of growth factors. Int J Radiat Oncol Biol Phys 62 (2005) 273-278
2. Anscher M.S., Chen L., Rabbani Z., et al. Recent progress in defining mechanisms and potential targets for prevention of normal tissue injury after radiation therapy. Int J Radiat Oncol Biol Phys 62 (2005) 255-259
3. Johnston C.J., Williams J.P., Elder A., et al. Inflammatory cell recruitment following thoracic irradiation. Exp Lung Res 30 (2004) 369-382
4. Suschek C.V., Mahotka C., Schnorr O., et al. UVB radiation-mediated expression of inducible nitric oxide synthase activity and the augmenting role of co-induced TNF-alpha in human skin endothelial cells. J Invest Dermatol 123 (2004) 950-957
5. Liang L., Hu D., Liu W., et al. Celecoxib reduces skin damage after radiation. Selective reduction of chemokine and receptor mRNA expression in irradiated skin but not in irradiated mammary tumor. Am J Clin Oncol 26 Suppl. 4 (2003) S114-S121
6. Wang H., and Kochevar I.E. Involvement of UVB-induced reactive oxygen species in TGF-beta biosynthesis and activation in keratinocytes. Free Radic Biol Med 38 (2005) 890-897
7. Luo D., Yaar M., Tsai A., et al. Solar-simulated irradiation evokes a persistent and biphasic IL-1alpha response. Exp Dermatol 13 (2004) 11-17
8. Zheng Q.Y., Mai K., Pan X.F., et al. Anti-inflammatory effects of esculentoside A. Chin J Pharmacol Toxicol 6 (1992) 221-224
9. Xiao Z.Y., Zheng Q.Y., Zhang J.P., et al. Effect of esculentoside A on autoimmunity in mice and its possible mechanisms. Acta Pharmacologica Sinica 23 (2002) 638-644
10. Xiao Z.Y., Zheng Q.Y., Yin M., et al. Inhibitory effect of esculentoside A on production of IL-1, 2 and prostaglandin E2. Acta Pharmacologica Sinica 25 (2004) 817-821
11. Ju D.W., Zheng Q.Y., Cao X., et al. Esculentoside A inhibits tumor necrosis factor, interleukin-1 and interleukin-6 production induced by lipopolysaccharide in mice. Pharmacology 56 (1998) 187-194
12. Inoue T., and Forgac M. Cysteine-mediated cross-linking indicates that subunit C of the V-ATPase is in close proximity to subunits E and G of the V1domain and subunit a of the V0 domain. J Biol Chem 280 (2005) 27896-27903
13. Chen Y., Hyrien O., Williams J.P., et al. Interleukin (IL)-1a and IL-6. applications to the predictive diagnostic testing of radiation pneumonitis. Int J Radiat Oncol Biol Phys 62 (2005) 260-266
14. Chen Y., Rubin P., Williams J.P., et al. Circulating IL-6 as a predictor of radiation pneumonitis. Int J Radiat Oncol Biol Phys 49 (2001) 641-648
15. Okunieff P., Augustine E., Hicks J.E., et al. Pentoxifylline in the treatment of radiation-induced fibrosis. J Clin Oncol 22 (2004) 2207-2213
16. Johnston C.J., Williams J.P., Okunieff P., et al. Radiation-induced pulmonary fibrosis. Examination of chemokine and chemokine receptor families. Radiat Res 157 (2002) 256-265
17. Ding I., Liu W., Sun J., et al. FGF1 and VEGF mediated angiogenesis in KHT tumor-bearing mice. Adv Exp Med Biol 530 (2003) 603-609
18. Rubin P., Constine L.S., Fajardo L.F., et al., RTOG Late Effects Working Group. Overview. Late Effects of Normal Tissues (LENT) scoring system. Int J Radiat Oncol Biol Phys 31 (1995) 1041-1042
19. Chiang C.S., Liu W.C., Jung S.M., et al. Compartmental responses after thoracic irradiation of mice. Strain differences. Int J Radiat Oncol Biol Phys 62 (2005) 862-871
20. Zelefsky M.J., Fuks Z., Hunt M., et al. High-dose intensity modulated radiation therapy for prostate cancer. Early toxicity and biochemical outcomes in 772 patients. Int J Radiat Oncol Biol Phys 53 (2002) 1111-1116
21. Burmeister B.H., Smithers B.M., Davis S., et al. Radiation therapy following nodal surgery for melanoma. An analysis of late toxicity. ANZ J Surg 72 (2002) 344-348
22. Williams J.P., Hernady E., Johnston C.J., et al. Effect of administration of lovastatin on the development of late pulmonary effects after whole-lung irradiation in a murine model. Radiat Res 161 (2004) 560-567
23. Gore E. Celecoxib and radiation therapy in non-small-cell lung cancer. Oncology 18 Suppl. 14 (2004) S10-S14
24. Liu W., Chen Y., Wang W., et al. Combination of radiation and celebrex (celecoxib) reduce mammary and lung tumor growth. Am J Clin Oncol 26 Suppl. 4 (2003) S103-S109
25. Rajalalitha P., and Vali S. Molecular pathogenesis of oral submucous fibrosis. A collagen metabolic disorder. J Oral Pathol Med 34 (2005) 321-328
26. Cosgrove G.P., Brown K.K., Schiemann W.P., et al. Pigment epithelium-derived factor in idiopathic pulmonary fibrosis. A role in aberrant angiogenesis. Am J Respir Crit Care Med 170 (2004) 242-251
27. Martin M., Lefaix J., and Delanian S. TGF-beta1 and radiation fibrosis. A master switch and a specific therapeutic target?. Int J Radiat Oncol Biol Phys 47 (2000) 277-290
28. Chen L., Brizel D.M., Rabbani Z.N., et al. The protective effect of recombinant human keratinocyte growth factor on radiation-induced pulmonary toxicity in rats. Int J Radiat Oncol Biol Phys 60 (2004) 1520-1529
29. Rubin P., Johnston C.J., Williams J.P., et al. A perpetual cascade of cytokines postirradiation leads to pulmonary fibrosis. Int J Radiat Oncol Biol Phys 33 (1995) 99-109
30. Forrester J.S., and Bick-Forrester J. Persistence of inflammatory cytokines cause a spectrum of chronic progressive diseases. Implications for therapy. Med Hypotheses 65 (2005) 227-231
31. Nordal R.A., and Wong C.S. Molecular targets in radiation-induced blood-brain barrier disruption. Int J Radiat Oncol Biol Phys 62 (2005) 279-287
32. Rube C.E., Wilfert F., Uthe D., et al. Increased expression of pro-inflammatory cytokines as a cause of lung toxicity after combined treatment with gemcitabine and thoracic irradiation. Radiother Oncol 72 (2004) 231-241
33. Hasegawa M., Sato S., and Takehara K. Augmented production of chemokines (monocyte chemotactic protein-1 (MCP-1)), macrophage inflammatory protein-1alpha (MIP-1alpha) and MIP-1beta) in patients with systemic sclerosis. MCP-1 and MIP-1alpha may be involved in the development of pulmonary fibrosis. Clin Exp Immunol 117 (1999) 159-165
34. Kanno K., Tazuma S., Nishioka T., et al. Angiotensin II participates in hepatic inflammation and fibrosis through MCP-1 expression. Dig Dis Sci 50 (2005) 942-948
35. Kagitani S., Ueno H., Hirade S., et al. Tranilast attenuates myocardial fibrosis in association with suppression of monocyte/macrophage infiltration in DOCA/salt hypertensive rats. J Hypertens 22 (2004) 1007-1015
36. Okuma T., Terasaki Y., Kaikita K., et al. C-C chemokine receptor 2 (CCR2) deficiency improves bleomycin-induced pulmonary fibrosis by attenuation of both macrophage infiltration and production of macrophage-derived matrix metalloproteinases. J Pathol 204 (2004) 594-604
37. McKinney L.C., Aquilla E.M., Coffin D., et al. Ionizing radiation potentiates the induction of nitric oxide synthase by interferon-gamma and/or lipopolysaccharide in murine macrophage cell lines. Role of tumor necrosis factor-alpha. Ann NY Acad Sci 899 (2000) 61-68
38. Miralbell R., Zietman A., Okunieff P., et al. Fractionation sensitivity and immunological status in radiation-treated murine sarcomas. Int J Radiat Oncol Biol Phys 18 (1990) 867-872
39. Kilbridge K.L., and Kantoff P. Intravesical therapy for superficial bladder cancer. Is it a wash?. J Clin Oncol 12 (1994) 1-4