Detection of local mast-cell activity in patients with food hypersensitivity

Journal of Investigational Allergology and Clinical Immunology

Volumn 17, Issue 5, 2007, Pages 314-320

  Peterson, Christer G B ^a,e   Hansson, T ^a,b   Skott, A ^c   Bengtsson, U ^d   Ahlstedt, S ^b,c   Magnusson, J ^d  

^a UPPSALA UNIVERSITY   (Sweden)

^b KAROLINSKA INSTITUTE   (Sweden)

^c Thermo Fisher Scientific   (United States)

^d SAHLGRENSKA UNIVERSITY HOSPITAL   (Sweden)

^e UPPSALA UNIVERSITY HOSPITAL   (Sweden)

Author keywords

Asthma; Eosinophil; EPX; Food hypersensitivity; Gastrointestinal; Mast cell; Tryptase

Indexed keywords

EOSINOPHIL CATIONIC PROTEIN; FOOD ANTIGEN; IMMUNOGLOBULIN E; PROTEINASE INHIBITOR; TRYPTASE;

ADULT; AGED; ARTICLE; CELL ACTIVITY; CLINICAL ARTICLE; CLINICAL TRIAL; CONTROLLED CLINICAL TRIAL; CONTROLLED STUDY; DOSE RESPONSE; DOUBLE BLIND PROCEDURE; DRUG EFFECT; FECES ANALYSIS; FOOD ALLERGY; GASTROINTESTINAL SYMPTOM; HUMAN; MAST CELL; MEASUREMENT; PRICK TEST; RANDOMIZED CONTROLLED TRIAL; SYMPTOMATOLOGY;

ADULT; AGED; EOSINOPHILS; FECES; FEMALE; FOOD HYPERSENSITIVITY; HUMANS; MALE; MAST CELLS; MIDDLE AGED; PROTEASE INHIBITORS; TRYPTASES;

EID: 35548985482     PISSN: 10189068     EISSN: 16980808     Source Type: Journal    
DOI: None     Document Type: Article

References (24)

1. Bengtsson U, Nilsson-Balknas U, Hanson LA, Ahlstedt S. Double blind, placebo controlled food reactions do not correlate to IgE allergy in the diagnosis of staple food related gastrointestinal symptoms. Gut. 1996;39:130-5.
2. Bischoff SC, Mayer J, Wedemeyer J, Meier PN, Zeck-Kapp G, Wedi B, Kapp A, Cetin Y, Gebel M, Manns MP. Colonoscopic allergen provocation (COLAP): a new diagnostic approach for gastrointestinal food allergy. Gut. 1997;40:745-53.
3. Bischoff SC, Herrmann A, Mayer J, Manns MP. Food allergy in patients with gastrointestinal disease. Monogr Allergy. 1996;32:130-42.
4. Bengtsson U, Knutson TW, Knutson L, Dannaeus A, Hallgren R, Ahlstedt S. Eosinophil cationic protein and histamine after intestinal challenge in patients with cow's milk intolerance. J Allergy Clin Immunol. 1997;100:216-21.
5. Bock SA. In vivo diagnosis: skin testing and oral challenge procedures. In: Metcalfe DD, Sampson H, Simon RA, editors. Food allergy. Oxford: Blackwell Scientific Publications; 1997. p. 151-65.
6. Bruijnzeel-Koomen C, Ortolani C, Aas K, Bindslev-Jensen C, Bjorksten B, Moneret-Vautrin D, Wuthrich B. Adverse reactions to food. European Academy of Allergology and Clinical Immunology Subcommittee. Allergy. 1995;50:623-35.
7. Gellerstedt M, Magnusson J, Grajo U, Ahlstedt S, Bengtsson U. Interpretation of subjective symptoms in double-blind placebo-controlled food challenges - interobserver reliability. Allergy. 2004;59:354-6.
8. Vila L, Sanz ML, Sanchez-Lopez G, Garcia-Aviles C, Dieguez I. Variations of serum eosinophil cationic protein and tryptase, measured in serum and saliva, during the course of immediate allergic reactions to foods. Allergy. 2001;56:568-72.
9. Zar S, Kumar D, Benson MJ. Food hypersensitivity and irritable bowel syndrome. Aliment Pharmacol Ther. 2001;15:439-49.
10. Schwartz L, Huff T. Biology of mast cells and basophils. In: Middleton E, Reed CE, Ellis EF, Adkinson NF, Yunginger JW, Busse WW, editors. Allergy. Principles and practice. St. Louis: Mosby; 1993. p 135-68.
11. Stenton GR, Vliagoftis H, Befus AD. Role of intestinal mast cells in modulating gastrointestinal pathophysiology. Ann Allergy Asthma Immunol. 1998;81:1-11.
12. Crowe SE, Perdue MH. Gastrointestinal food hypersensitivity: basic mechanisms of pathophysiology. Gastroenterology. 1992;103:1075-95.
13. Raithel M, Pacurar A, Winterkamp S, Dalbay S, Ell C, Hahn EG. Analysis and characteristics of mast cell tryptase and eosinophilic cationic protein from human gut mucosa in gastrointestinal allergy. Monogr Allergy. 1996;32:143-56.
14. Sampson HA, Mendelson L, Rosen JP. Fatal and near-fatal anaphylactic reactions to food in children and adolescents. N Engl J Med. 1992;327:380-4.
15. Johansson SGO, Bieber T, Dahl R, Friedmann P, Lanier B, Lockey R, Motala C, Ortega Martell J, Platts-Mills TA, Ring J, Thien F, Van Cauwenberge P, Williams H. Revised nomenclature for allergy for global use: Report of the Nomenclature Review Committee of the World Allergy Organization, October 2003. J Allergy Clin Immunol. 2004;113:832-6.
16. Magnusson J, Gellerstedt M, Ahlstedt S, Andersson B, Bengtsson U, Hansson T, Peterson C. A kinetic study in adults with food hypersensitivity assessed as eosinophil activation in fecal samples. Clin Exp Allergy. 2003;33:1052-9.
17. Fasano A, Catassi C. Current approaches to diagnosis and treatment of celiac disease: an evolving spectrum. Gastroenterol. 2001;120:636-51.
18. Thompson WG, Longstreth GF, Drossman DA, Heaton KW, Irvine EJ, Muller-Lissner SA. Functional bowel disorders and functional abdominal pain. Gut. 1999;45 Suppl 2:II43-7.
19. Peterson CGB, Eklund E, Taha Y, Raab Y, Carlson M. A new method for the quantification of neutrophil and eosinophil cationic proteins in feces: establishment of normal levels and clinical application in patients with inflammatory bowel disease. Am J Gastroenterol. 2002;97:1755-62.
20. Schwartz LB, Bradford TR, Lee DC, Chlebowski JF. Immunologic and physicochemical evidence for conformational changes occuring on conversion of human mast cell tryptase from active tetramer to inactive monomer. Production of monoclonal antibodies recognizing acive tryptase. J Immunol. 1990;144:2304-11.
21. Aas K, Backman A, Belin L, Weeke B. Standardization of allergen extracts with appropriate methods. The combined use of skin prick testing and radio-allergosorbent tests. Allergy. 1978;33:130-7.
22. Santos J, Bayarri C, Saperas E, Nogueiras C, Antolin M, Mourelle M, Cadahia A, Malagelada JR. Characterisation of immune mediator release during the immediate response to segmental mucosal challenge in the jejunum of patients with food allergy. Gut. 1999;45:553-8.
23. Barbara G, De Giorgio R, Stanghellini V, Cremon C, Corinaldesi R. A role for inflammation in irritable bowel syndrome? Gut. 2002;51:i41-4.
24. Lettesjö H, Hansson T, Peterson C, Ung KA, Ringström G, Abrahamsson H, Simrén M. Detection of inflammatory markers