Capacitative calcium entry contributes to the differential transactivation of the epidermal growth factor receptor in response to thiazolidinediones

Molecular Pharmacology

Volumn 72, Issue 5, 2007, Pages 1146-1156

  Dewar, Brian J ^a   Gardner, Olivia S ^a   Chen, Ching Shih ^d   Earp, H Shelton ^a,b   Samet, James M ^a,c   Graves, Lee M ^a,b  

^a UNIVERSITY OF NORTH CAROLINA   (United States)

^b UNIVERSITY OF NORTH CAROLINA SCHOOL OF MEDICINE   (United States)

^c U S ENVIRONMENTAL PROTECTION AGENCY   (United States)

^d OHIO STATE UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CALCIUM; CIGLITAZONE; EPIDERMAL GROWTH FACTOR RECEPTOR; FOCAL ADHESION KINASE 2; MITOGEN ACTIVATED PROTEIN KINASE; PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR GAMMA; PROTEIN TYROSINE KINASE; PROTEIN TYROSINE PHOSPHATASE; TROGLITAZONE;

ANIMAL CELL; ARTICLE; CALCIUM TRANSPORT; CHELATION; CONTROLLED STUDY; DIABETES MELLITUS; DRUG BINDING; DRUG MECHANISM; ENZYME ACTIVATION; ENZYME INHIBITION; NONHUMAN; ONCOGENE SRC; PRIORITY JOURNAL; RAT; SIGNAL TRANSDUCTION;

ANIMALS; CALCIUM; CALCIUM SIGNALING; CELL LINE; CHELATING AGENTS; CHROMANS; EXTRACELLULAR SIGNAL-REGULATED MAP KINASES; FOCAL ADHESION KINASE 2; HYPOGLYCEMIC AGENTS; PHOSPHORYLATION; PPAR GAMMA; PROTEIN TYROSINE PHOSPHATASES; RATS; RECEPTOR, EPIDERMAL GROWTH FACTOR; SRC-FAMILY KINASES; THIAZOLIDINEDIONES; TRANS-ACTIVATION (GENETICS); TYROSINE;

EID: 35548978112     PISSN: 0026895X     EISSN: 15210111     Source Type: Journal    
DOI: 10.1124/mol.107.037549     Document Type: Article

References (47)

1. Avraham H, Park SY, Schinkmann K, and Avraham S (2000) RAFTK/Pyk2-mediated cellular signalling. Cell Signal 12:123-133.
2. Berridge MJ, Lipp P, and Bootman MD (2000) The versatility and universality of calcium signalling. Nat Rev Mol Cell Biol 1:11-21.
3. Biscardi JS, Maa MC, Tice DA, Cox ME, Leu TH, and Parsons SJ (1999) c-Src-mediated phosphorylation of the epidermal growth factor receptor on Tyr845 and Tyr1101 is associated with modulation of receptor function. J Biol Chem 274:8335-8343.
4. Bobe R, Yin X, Roussanne MC, Stepien O, Polidano E, Faverdin C, and Marche P (2003) Evidence for ERK1/2 activation by thrombin that is independent of EGFR transactivation. Am J Physiol Heart Circ Physiol 285:H745-H754.
5. Braun FJ, Aziz O, and Putney JW Jr (2003) 2-Aminoethoxydiphenyl borane activates a novel calcium-permeable cation channel. Mol Pharmacol 63:1304-1311.
6. Carpenter G, King LJ, and Cohen S (1978) Epidermal growth factor stimulates phosphorylation in membrane preparations in vitro. Nature 276:409-410, 1978.
7. Demetri GD, Fletcher CD, Mueller E, Sarraf P, Naujoks R, Campbell N, Spiegelman BM, and Singer S (1999) Induction of solid tumor differentiation by the peroxisome proliferator-activated receptor-gamma ligand troglitazone in patients with liposarcoma. Proc Natl Acad Sci U S A 96:3951-3956.
8. Dikic I, Tokiwa G, Lev S, Courtneidge SA, and Schlessinger J (1996) A role for Pyk2 and Src in linking G-protein-coupled receptors with MAP kinase activation. Nature 383:547-550.
9. Earp HS, Huckle WR, Dawson TL, Li X, Graves LM, and Dy R (1995) Angiotensin II activates at least two tyrosine kinases in rat liver epithelial cells. Separation of the major calcium-regulated tyrosine kinase from p125FAK. J Biol Chem 270:28440-28447.
10. Eguchi S, Numaguchi K, Iwasaki H, Matsumoto T, Yamakawa T, Utsunomiya H, Motley ED, Kawakatsu H, Owada KM, Hirata Y, et al. (1998) Calcium-dependent epidermal growth factor receptor transactivation mediates the angiotensin II-induced mitogen-activated protein kinase activation in vascular smooth muscle cells. J Biol Chem 273:8890-8896.
11. Elstner E, Muller C, Koshizuka K, Williamson EA, Park D, Asou H, Shintaku P, Said JW, Heber D, and Koeffler HP (1998) Ligands for peroxisome proliferator-activated receptorgamma and retinoic acid receptor inhibit growth and induce apoptosis of human breast cancer cells in vitro and in BNX mice. Proc Natl Acad Sci U S A 95:8806-8811.
12. Gardner OS, Dewar BJ, Earp HS, Samet JM, and Graves LM (2003) Dependence of peroxisome proliferator-activated receptor ligand-induced mitogen-activated protein kinase signaling on epidermal growth factor receptor transactivation. J Biol Chem 278:46261-46269.
13. Gardner OS, Dewar BJ, and Graves LM (2005a) Activation of mitogen-activated protein kinases by peroxisome proliferator-activated receptor ligands: an example of nongenomic signaling. Mol Pharmacol 68:933-941.
14. Gardner OS, Shiau CW, Chen CS, and Graves LM (2005b) Peroxisome proliferator-activated receptor γ-independent activation of p38 MAPK by thiazolidinediones involves calcium/calmodulin-dependent protein kinase II and protein kinase R: correlation with endoplasmic reticulum stress. J Biol Chem 280:10109-10118.
15. Goi T, Shipitsin M, Lu Z, Foster DA, Klinz SG, and Feig LA (2000) An EGF receptor/Ral-GTPase signaling cascade regulates c-Src activity and substrate specificity. EMBO J 19:623-630.
16. Graves LM, He Y, Lambert J, Hunter D, Li X, and Earp HS (1997) An intracellular calcium signal activates p70 but not p90 ribosomal S6 kinase in liver epithelial cells. J Biol Chem 272:1920-1928.
17. Kadota S, Fantus IG, Deragon G, Guyda HJ, Hersh B, and Posner BI (1987) Peroxide (s) of vanadium: a novel and potent insulin-mimetic agent which activates the insulin receptor kinase. Biochem Biophys Res Commun 147:259-266.
18. 2+ entry in endothelial cells. Eur J Pharmacol 373:111-120.
19. 2+ channels. Am J Physiol Cell Physiol 288:C389-C395.
20. 2+ depletion triggers apoptotic signals for endoplasmic reticulum (ER) overload response induced by overexpressed reticulon 3 (RTN3/HAP). J Cell Physiol 204:549-559.
21. Kubota T, Koshizuka K, Williamson EA, Asou H, Said JW, Holden S, Miyoshi I, and Koeffler HP (1998) Ligand for peroxisome proliferator-activated receptor gamma (troglitazone) has potent antitumor effect against human prostate cancer both in vitro and in vivo. Cancer Res 58:3344-3352.
22. Lehmann JM, Moore LB, Smith-Oliver TA, Wilkison WO, Willson TM, and Kliewer SA (1995) An antidiabetic thiazolidinedione is a high affinity ligand for peroxisome proliferator-activated receptor γ (PPAR γ). J Biol Chem 270:12953-12956.
23. 2 and the thiazolidinedione ciglitazone through peroxisome proliferator activator receptor γ-independent mechanisms involving reactive oxygenated species. J Biol Chem 277:29681-29685.
24. Li X, Dy RC, Cance WG, Graves LM, and Earp HS (1999) Interactions between two cytoskeleton-associated tyrosine kinases: calcium-dependent tyrosine kinase and focal adhesion tyrosine kinase. J Biol Chem 274:8917-8924.
25. Li X, Lee JW, Graves LM, and Earp HS (1998) Angiotensin II stimulates ERK via two pathways in epithelial cells: protein kinase C suppresses a G-protein coupled receptor-EGF receptor transactivation pathway. EMBO J 17:2574-2583.
26. Luttrell DK, Luttrell LM, and Parsons SJ (1988) Augmented mitogenic responsiveness to epidermal growth factor in murine fibroblasts that overexpress pp60c-src. Mol Cell Biol 8:497-501.
27. Mounho BJ and Thrall BD (1999) The extracellular signal-regulated kinase pathway contributes to mitogenic and antiapoptotic effects of peroxisome proliferators in vitro. Toxicol Appl Pharmacol 159:125-133.
28. Okada M and Nakagawa H (1988) Identification of a novel protein tyrosine kinase that phosphorylates pp60c-src and regulates its activity in neonatal rat brain. Biochem Biophys Res Commun 154:796-802.
29. Olayioye MA, Beuvink I, Horsch K, Daly JM, and Hynes NE (1999) ErbB receptor-induced activation of stat transcription factors is mediated by Src tyrosine kinases. J Biol Chem 274:17209-17218.
30. Palakurthi SS, Aktas H, Grubissich LM, Mortensen RM, and Halperin JA (2001) Anticancer effects of thiazolidinediones are independent of peroxisome proliferator-activated receptor gamma and mediated by inhibition of translation initiation. Cancer Res 61:6213-6218.
31. Prenzel N, Fischer OM, Streit S, Hart S, and Ullrich A (2001) The epidermal growth factor receptor family as a central element for cellular signal transduction and diversification. Endocr Relat Cancer 8:11-31.
32. Putney JW, Jr. (1986) A model for receptor-regulated calcium entry. Cell Calcium 7:1-12.
33. Rokos CL and Ledwith BJ (1997) Peroxisome proliferators activate extracellular signal-regulated kinases in immortalized mouse liver cells. J Biol Chem 272:13452-13457.
34. Rosen LB and Greenberg ME (1996) Stimulation of growth factor receptor signal transduction by activation of voltage-sensitive calcium channels. Proc Natl Acad Sci U S A 93:1113-1118.
35. Sato K, Nagao T, Kakumoto M, Kimoto M, Otsuki T, Iwasaki T, Tokmakov AA, Owada K, and Fukami Y (2002) Adaptor protein Shc is an isoform-specific direct activator of the tyrosine kinase c-Src. J Biol Chem 277:29568- 29576.
36. Schaller MD and Sasaki T (1997) Differential signaling by the focal adhesion kinase and cell adhesion kinase β. J Biol Chem 272:25319-25325.
37. Shah BH, Soh JW, and Catt KJ (2003) Dependence of gonadotropin-releasing hormone-induced neuronal MAPK signaling on epidermal growth factor receptor transactivation. J Biol Chem 278:2866-2875.
38. Shiau CW, Yang CC, Kulp SK, Chen KF, Chen CS, and Huang JW (2005) Thiazolidenediones mediate apoptosis in prostate cancer cells in part through inhibition of Bcl-xL/Bcl-2 functions independently of PPARgamma. Cancer Res 65:1561-1569.
39. Thomas SM and Brugge JS (1997) Cellular functions regulated by Src family kinases. Annu Rev Cell Dev Biol 13:513-609.
40. Trudel S, Paquet MR, and Grinstein S (1991) Mechanism of vanadate-induced activation of tyrosine phosphorylation and of the respiratory burst in HL60 cells. Role of reduced oxygen metabolites. Biochem J 276:611-619.
41. Tsubouchi Y, Sano H, Kawahito Y, Mukai S, Yamada R, Kohno M, Inoue K, Hla T, and Kondo M (2000) Inhibition of human lung cancer cell growth by the peroxisome proliferator-activated receptor-gamma agonists through induction of apoptosis. Biochem Biophys Res Commun 270:400-405.
42. Ullrich A and Schlessinger J (1990) Signal transduction by receptors with tyrosine kinase activity. Cell 61:203-212.
43. Wetzker R and Bohmer FD (2003) Transactivation joins multiple tracks to the ERK/MAPK cascade. Nat Rev Mol Cell Biol 4:651-657.
44. Yki-Järvinen H (2004) Thiazolidinediones. N Engl J Med 351:1106-1118.
45. Yu H, Li X, Marchetto GS, Dy R, Hunter D, Calvo B, Dawson TL, Wilm M, Anderegg RJ, Graves LM, et al. (1996) Activation of a novel calcium-dependent protein-tyrosine kinase. Correlation with c-Jun N-terminal kinase but not mitogen-activated protein kinase activation. J Biol Chem 271:29993-29998.
46. Zhao Y, Sudol M, Hanafusa H, and Krueger J (1992) Increased tyrosine kinase activity of c-Src during calcium-induced keratinocyte differentiation. Proc Natl Acad Sci U S A 89:8298-8302.
47. Zwick E, Daub H, Aoki N, Yamaguchi-Aoki Y, Tinhofer I, Maly K, and Ullrich A (1997) Critical role of calcium- dependent epidermal growth factor receptor transactivation in PC12 cell membrane depolarization and bradykinin signaling. J Biol Chem 272:24767-24770.