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Volumn 368, Issue 2, 2007, Pages 273-285

Non-pathogenic Sindbis virus causes hemorrhagic fever in the absence of alpha/beta and gamma interferons

Author keywords

Alphavirus; Interferon; Sindbis; Viral hemorrhagic fever

Indexed keywords

ALPHA INTERFERON; ALPHA INTERFERON RECEPTOR; BETA INTERFERON; BETA INTERFERON RECEPTOR; GAMMA INTERFERON; GAMMA INTERFERON RECEPTOR;

EID: 35548955462     PISSN: 00426822     EISSN: 10960341     Source Type: Journal    
DOI: 10.1016/j.virol.2007.06.039     Document Type: Article
Times cited : (39)

References (60)
  • 2
    • 4744352571 scopus 로고    scopus 로고
    • Role of NK and NKT cells in the immunopathogenesis of HCV-induced hepatitis
    • Ahmad A., and Alvarez F. Role of NK and NKT cells in the immunopathogenesis of HCV-induced hepatitis. J. Leukoc. Biol. 76 (2004) 743-759
    • (2004) J. Leukoc. Biol. , vol.76 , pp. 743-759
    • Ahmad, A.1    Alvarez, F.2
  • 3
    • 0036628966 scopus 로고    scopus 로고
    • Viruses and the type I interferon antiviral system: induction and evasion
    • Basler C.F., and Garcia-Sastre A. Viruses and the type I interferon antiviral system: induction and evasion. Int. Rev. Immunol. 21 (2002) 305-337
    • (2002) Int. Rev. Immunol. , vol.21 , pp. 305-337
    • Basler, C.F.1    Garcia-Sastre, A.2
  • 4
    • 0035854473 scopus 로고    scopus 로고
    • Interferon-gamma-mediated site-specific clearance of alphavirus from CNS neurons
    • Binder G.K., and Griffin D.E. Interferon-gamma-mediated site-specific clearance of alphavirus from CNS neurons. Science 293 (2001) 303-306
    • (2001) Science , vol.293 , pp. 303-306
    • Binder, G.K.1    Griffin, D.E.2
  • 5
    • 0031754296 scopus 로고    scopus 로고
    • Early cytokine responses to viral infections and their roles in shaping endogenous cellular immunity
    • Biron C.A., Cousens L.P., Ruzek M.C., Su H.C., and Salazar-Mather T.P. Early cytokine responses to viral infections and their roles in shaping endogenous cellular immunity. Adv. Exp. Med. Biol. 452 (1998) 143-149
    • (1998) Adv. Exp. Med. Biol. , vol.452 , pp. 143-149
    • Biron, C.A.1    Cousens, L.P.2    Ruzek, M.C.3    Su, H.C.4    Salazar-Mather, T.P.5
  • 6
    • 20544441437 scopus 로고    scopus 로고
    • Pathogenesis of viral hemorrhagic fever
    • Bray M. Pathogenesis of viral hemorrhagic fever. Curr. Opin. Immunol. 17 (2005) 399-403
    • (2005) Curr. Opin. Immunol. , vol.17 , pp. 399-403
    • Bray, M.1
  • 7
    • 17444384202 scopus 로고    scopus 로고
    • Gamma interferon-dependent, noncytolytic clearance of Sindbis virus infection from neurons in vitro
    • Burdeinick-Kerr R., and Griffin D.E. Gamma interferon-dependent, noncytolytic clearance of Sindbis virus infection from neurons in vitro. J. Virol. 79 (2005) 5374-5385
    • (2005) J. Virol. , vol.79 , pp. 5374-5385
    • Burdeinick-Kerr, R.1    Griffin, D.E.2
  • 8
    • 34249804520 scopus 로고    scopus 로고
    • Synergistic roles of antibody and interferon in noncytolytic clearance of Sindbis virus from different regions of the central nervous system
    • Burdeinick-Kerr R., Wind J., and Griffin D.E. Synergistic roles of antibody and interferon in noncytolytic clearance of Sindbis virus from different regions of the central nervous system. J. Virol. 81 (2007) 5628-5636
    • (2007) J. Virol. , vol.81 , pp. 5628-5636
    • Burdeinick-Kerr, R.1    Wind, J.2    Griffin, D.E.3
  • 9
    • 0034067890 scopus 로고    scopus 로고
    • Control of Sindbis virus infection by antibody in interferon-deficient mice
    • Byrnes A.P., Durbin J.E., and Griffin D.E. Control of Sindbis virus infection by antibody in interferon-deficient mice. J. Virol. 74 (2000) 3905-3908
    • (2000) J. Virol. , vol.74 , pp. 3905-3908
    • Byrnes, A.P.1    Durbin, J.E.2    Griffin, D.E.3
  • 10
    • 0036889113 scopus 로고    scopus 로고
    • The role of IFN-gamma in immune responses to viral infections of the central nervous system
    • Chesler D.A., and Reiss C.S. The role of IFN-gamma in immune responses to viral infections of the central nervous system. Cytokine Growth Factor Rev. 13 (2002) 441-454
    • (2002) Cytokine Growth Factor Rev. , vol.13 , pp. 441-454
    • Chesler, D.A.1    Reiss, C.S.2
  • 11
    • 0003684486 scopus 로고    scopus 로고
    • Molecular biology of multiple organ dysfunction syndrome: injury, adaptation, and apoptosis
    • Cobb J.P., Buchman T.G., Karl I.E., and Hotchkiss R.S. Molecular biology of multiple organ dysfunction syndrome: injury, adaptation, and apoptosis. Surg. Infect. (Larchmt.) 1 (2000) 207-213
    • (2000) Surg. Infect. (Larchmt.) , vol.1 , pp. 207-213
    • Cobb, J.P.1    Buchman, T.G.2    Karl, I.E.3    Hotchkiss, R.S.4
  • 13
    • 0037128167 scopus 로고    scopus 로고
    • Interferon alpha/beta and interleukin 12 responses to viral infections: pathways regulating dendritic cell cytokine expression in vivo
    • Dalod M., Salazar-Mather T.P., Malmgaard L., Lewis C., Asselin-Paturel C., Briere F., Trinchieri G., and Biron C.A. Interferon alpha/beta and interleukin 12 responses to viral infections: pathways regulating dendritic cell cytokine expression in vivo. J. Exp. Med. 195 (2002) 517-528
    • (2002) J. Exp. Med. , vol.195 , pp. 517-528
    • Dalod, M.1    Salazar-Mather, T.P.2    Malmgaard, L.3    Lewis, C.4    Asselin-Paturel, C.5    Briere, F.6    Trinchieri, G.7    Biron, C.A.8
  • 14
  • 15
    • 0030024563 scopus 로고    scopus 로고
    • Targeted disruption of the mouse Stat1 gene results in compromised innate immunity to viral disease
    • Durbin J.E., Hackenmiller R., Simon M.C., and Levy D.E. Targeted disruption of the mouse Stat1 gene results in compromised innate immunity to viral disease. Cell 84 (1996) 443-450
    • (1996) Cell , vol.84 , pp. 443-450
    • Durbin, J.E.1    Hackenmiller, R.2    Simon, M.C.3    Levy, D.E.4
  • 16
    • 33644970005 scopus 로고    scopus 로고
    • Infectious diseases. Massive outbreak draws fresh attention to little-known virus
    • Enserink M. Infectious diseases. Massive outbreak draws fresh attention to little-known virus. Science 311 (2006) 1085
    • (2006) Science , vol.311 , pp. 1085
    • Enserink, M.1
  • 17
    • 33646555810 scopus 로고    scopus 로고
    • Type 1 interferons and the virus-host relationship: a lesson in detente
    • Garcia-Sastre A., and Biron C.A. Type 1 interferons and the virus-host relationship: a lesson in detente. Science 312 (2006) 879-882
    • (2006) Science , vol.312 , pp. 879-882
    • Garcia-Sastre, A.1    Biron, C.A.2
  • 19
    • 0017226982 scopus 로고
    • Role of the immune response in age-dependent resistance of mice to encephalitis due to Sindbis virus
    • Griffin D.E. Role of the immune response in age-dependent resistance of mice to encephalitis due to Sindbis virus. J. Infect. Dis. 133 (1976) 456-464
    • (1976) J. Infect. Dis. , vol.133 , pp. 456-464
    • Griffin, D.E.1
  • 20
    • 0001552353 scopus 로고    scopus 로고
    • Alphaviruses
    • Knipe D.M., and Howley P.M. (Eds), Lippincott, Williams & Wilkins, Philadelphia
    • Griffin D.E. Alphaviruses. In: Knipe D.M., and Howley P.M. (Eds). Fields Virology (2001), Lippincott, Williams & Wilkins, Philadelphia 917-962
    • (2001) Fields Virology , pp. 917-962
    • Griffin, D.E.1
  • 21
    • 0021012179 scopus 로고
    • Immune responses to acute alphavirus infection of the central nervous system: Sindbis virus encephalitis in mice
    • Griffin D.E., Mokhtarian F., Park M.M., and Hirsch R.L. Immune responses to acute alphavirus infection of the central nervous system: Sindbis virus encephalitis in mice. Prog. Brain Res. 59 (1983) 11-21
    • (1983) Prog. Brain Res. , vol.59 , pp. 11-21
    • Griffin, D.E.1    Mokhtarian, F.2    Park, M.M.3    Hirsch, R.L.4
  • 22
    • 0033179072 scopus 로고    scopus 로고
    • Cytokine-induced viral purging-role in viral pathogenesis
    • Guidotti L.G., and Chisari F.V. Cytokine-induced viral purging-role in viral pathogenesis. Curr. Opin. Microbiol. 2 (1999) 388-391
    • (1999) Curr. Opin. Microbiol. , vol.2 , pp. 388-391
    • Guidotti, L.G.1    Chisari, F.V.2
  • 24
    • 13844296660 scopus 로고    scopus 로고
    • Viruses evade the immune system through type I interferon-mediated STAT2-dependent, but STAT1-independent, signaling
    • Hahm B., Trifilo M.J., Zuniga E.I., and Oldstone M.B. Viruses evade the immune system through type I interferon-mediated STAT2-dependent, but STAT1-independent, signaling. Immunity 22 (2005) 247-257
    • (2005) Immunity , vol.22 , pp. 247-257
    • Hahm, B.1    Trifilo, M.J.2    Zuniga, E.I.3    Oldstone, M.B.4
  • 26
    • 21244457939 scopus 로고    scopus 로고
    • Homeostatic role of interferons conferred by inhibition of IL-1-mediated inflammation and tissue destruction
    • Hu X., Ho H.H., Lou O., Hidaka C., and Ivashkiv L.B. Homeostatic role of interferons conferred by inhibition of IL-1-mediated inflammation and tissue destruction. J. Immunol. 175 (2005) 131-138
    • (2005) J. Immunol. , vol.175 , pp. 131-138
    • Hu, X.1    Ho, H.H.2    Lou, O.3    Hidaka, C.4    Ivashkiv, L.B.5
  • 27
    • 0015308778 scopus 로고
    • Age-dependent resistance to viral encephalitis: studies of infections due to Sindbis virus in mice
    • Johnson R.T., McFarland H.F., and Levy S.E. Age-dependent resistance to viral encephalitis: studies of infections due to Sindbis virus in mice. J. Infect. Dis. 125 (1972) 257-262
    • (1972) J. Infect. Dis. , vol.125 , pp. 257-262
    • Johnson, R.T.1    McFarland, H.F.2    Levy, S.E.3
  • 28
    • 0034797275 scopus 로고    scopus 로고
    • Identification of genes involved in the host response to neurovirulent alphavirus infection
    • Johnston C., Jiang W., Chu T., and Levine B. Identification of genes involved in the host response to neurovirulent alphavirus infection. J. Virol. 75 (2001) 10431-10445
    • (2001) J. Virol. , vol.75 , pp. 10431-10445
    • Johnston, C.1    Jiang, W.2    Chu, T.3    Levine, B.4
  • 29
    • 0037423838 scopus 로고    scopus 로고
    • STAT1-dependent innate immunity to a Norwalk-like virus
    • Karst S.M., Wobus C.E., Lay M., Davidson J., and Virgin H.W. STAT1-dependent innate immunity to a Norwalk-like virus. Science 299 (2003) 1575-1578
    • (2003) Science , vol.299 , pp. 1575-1578
    • Karst, S.M.1    Wobus, C.E.2    Lay, M.3    Davidson, J.4    Virgin, H.W.5
  • 30
    • 0346119029 scopus 로고    scopus 로고
    • Role of interferon-gamma and nitric oxide in the neuropathogenesis of avirulent Semliki Forest virus infection
    • Keogh B., Atkins G.J., Mills K.H., and Sheahan B.J. Role of interferon-gamma and nitric oxide in the neuropathogenesis of avirulent Semliki Forest virus infection. Neuropathol. Appl. Neurobiol. 29 (2003) 553-562
    • (2003) Neuropathol. Appl. Neurobiol. , vol.29 , pp. 553-562
    • Keogh, B.1    Atkins, G.J.2    Mills, K.H.3    Sheahan, B.J.4
  • 31
    • 0031869503 scopus 로고    scopus 로고
    • Adaptation of Sindbis virus to BHK cells selects for use of heparan sulfate as an attachment receptor
    • Klimstra W.B., Ryman K.D., and Johnston R.E. Adaptation of Sindbis virus to BHK cells selects for use of heparan sulfate as an attachment receptor. J. Virol. 72 (1998) 7357-7366
    • (1998) J. Virol. , vol.72 , pp. 7357-7366
    • Klimstra, W.B.1    Ryman, K.D.2    Johnston, R.E.3
  • 32
    • 0032757364 scopus 로고    scopus 로고
    • Infection of neonatal mice with Sindbis virus results in a systemic inflammatory response syndrome
    • Klimstra W.B., Ryman K.D., Bernard K.A., Nguyen K.B., Biron C.A., and Johnston R.E. Infection of neonatal mice with Sindbis virus results in a systemic inflammatory response syndrome. J. Virol. 73 (1999) 10387-10398
    • (1999) J. Virol. , vol.73 , pp. 10387-10398
    • Klimstra, W.B.1    Ryman, K.D.2    Bernard, K.A.3    Nguyen, K.B.4    Biron, C.A.5    Johnston, R.E.6
  • 34
    • 0036828160 scopus 로고    scopus 로고
    • Age-dependent resistance to lethal alphavirus encephalitis in mice: analysis of gene expression in the central nervous system and identification of a novel interferon-inducible protective gene, mouse ISG12
    • Labrada L., Liang X.H., Zheng W., Johnston C., and Levine B. Age-dependent resistance to lethal alphavirus encephalitis in mice: analysis of gene expression in the central nervous system and identification of a novel interferon-inducible protective gene, mouse ISG12. J. Virol. 76 (2002) 11688-11703
    • (2002) J. Virol. , vol.76 , pp. 11688-11703
    • Labrada, L.1    Liang, X.H.2    Zheng, W.3    Johnston, C.4    Levine, B.5
  • 35
    • 9644266788 scopus 로고    scopus 로고
    • Sindbis viruses and other alphaviruses as cause of human arthritic disease
    • Laine M., Luukkainen R., and Toivanen A. Sindbis viruses and other alphaviruses as cause of human arthritic disease. J. Int. Med. 256 (2004) 457-471
    • (2004) J. Int. Med. , vol.256 , pp. 457-471
    • Laine, M.1    Luukkainen, R.2    Toivanen, A.3
  • 42
    • 33947360241 scopus 로고    scopus 로고
    • Murine norovirus 1 infection is associated with histopathological changes in immunocompetent hosts, but clinical disease is prevented by STAT1-dependent interferon responses
    • Mumphrey S.M., Changotra H., Moore T.N., Heimann-Nichols E.R., Wobus C.E., Reilly M.J., Moghadamfalahi M., Shukla D., and Karst S.M. Murine norovirus 1 infection is associated with histopathological changes in immunocompetent hosts, but clinical disease is prevented by STAT1-dependent interferon responses. J. Virol. 81 (2007) 3251-3263
    • (2007) J. Virol. , vol.81 , pp. 3251-3263
    • Mumphrey, S.M.1    Changotra, H.2    Moore, T.N.3    Heimann-Nichols, E.R.4    Wobus, C.E.5    Reilly, M.J.6    Moghadamfalahi, M.7    Shukla, D.8    Karst, S.M.9
  • 43
    • 0030060232 scopus 로고    scopus 로고
    • An absolute and restricted requirement for IL-12 in natural killer cell IFN-gamma production and antiviral defense. Studies of natural killer and T cell responses in contrasting viral infections
    • Orange J.S., and Biron C.A. An absolute and restricted requirement for IL-12 in natural killer cell IFN-gamma production and antiviral defense. Studies of natural killer and T cell responses in contrasting viral infections. J. Immunol. 156 (1996) 1138-1142
    • (1996) J. Immunol. , vol.156 , pp. 1138-1142
    • Orange, J.S.1    Biron, C.A.2
  • 45
    • 4744364574 scopus 로고    scopus 로고
    • Alternative activation of STAT1 and STAT3 in response to interferon-gamma
    • Qing Y., and Stark G.R. Alternative activation of STAT1 and STAT3 in response to interferon-gamma. J. Biol. Chem. 279 (2004) 41679-41685
    • (2004) J. Biol. Chem. , vol.279 , pp. 41679-41685
    • Qing, Y.1    Stark, G.R.2
  • 47
    • 0036476551 scopus 로고    scopus 로고
    • Stat1-dependent and -independent pathways in IFN-gamma-dependent signaling
    • Ramana C.V., Gil M.P., Schreiber R.D., and Stark G.R. Stat1-dependent and -independent pathways in IFN-gamma-dependent signaling. Trends Immunol. 23 (2002) 96-101
    • (2002) Trends Immunol. , vol.23 , pp. 96-101
    • Ramana, C.V.1    Gil, M.P.2    Schreiber, R.D.3    Stark, G.R.4
  • 48
    • 0034056841 scopus 로고    scopus 로고
    • Alpha/beta interferon protects adult mice from fatal Sindbis virus infection and is an important determinant of cell and tissue tropism
    • Ryman K.D., Klimstra W.B., Nguyen K.B., Biron C.A., and Johnston R.E. Alpha/beta interferon protects adult mice from fatal Sindbis virus infection and is an important determinant of cell and tissue tropism. J. Virol. 74 (2000) 3366-3378
    • (2000) J. Virol. , vol.74 , pp. 3366-3378
    • Ryman, K.D.1    Klimstra, W.B.2    Nguyen, K.B.3    Biron, C.A.4    Johnston, R.E.5
  • 49
    • 0036211422 scopus 로고    scopus 로고
    • Effects of PKR/RNase L-dependent and alternative antiviral pathways on alphavirus replication and pathogenesis
    • Ryman K.D., White L.J., Johnston R.E., and Klimstra W.B. Effects of PKR/RNase L-dependent and alternative antiviral pathways on alphavirus replication and pathogenesis. Viral Immunol. 15 (2002) 53-76
    • (2002) Viral Immunol. , vol.15 , pp. 53-76
    • Ryman, K.D.1    White, L.J.2    Johnston, R.E.3    Klimstra, W.B.4
  • 50
    • 33947365512 scopus 로고    scopus 로고
    • Heparan sulfate binding can contribute to the neurovirulence of neuroadapted and nonneuroadapted Sindbis viruses
    • Ryman K.D., Gardner C.L., Burke C.W., Meier K.C., Thompson J.M., and Klimstra W.B. Heparan sulfate binding can contribute to the neurovirulence of neuroadapted and nonneuroadapted Sindbis viruses. J. Virol. 81 (2007) 3563-3573
    • (2007) J. Virol. , vol.81 , pp. 3563-3573
    • Ryman, K.D.1    Gardner, C.L.2    Burke, C.W.3    Meier, K.C.4    Thompson, J.M.5    Klimstra, W.B.6
  • 51
    • 33846847832 scopus 로고    scopus 로고
    • Early restriction of alphavirus replication and dissemination contributes to age-dependent attenuation of systemic hyperinflammatory disease
    • Ryman K.D., Gardner C.L., Meier K.C., Biron C.A., Johnston R.E., and Klimstra W.B. Early restriction of alphavirus replication and dissemination contributes to age-dependent attenuation of systemic hyperinflammatory disease. J. Gen. Virol. 88 (2007) 518-529
    • (2007) J. Gen. Virol. , vol.88 , pp. 518-529
    • Ryman, K.D.1    Gardner, C.L.2    Meier, K.C.3    Biron, C.A.4    Johnston, R.E.5    Klimstra, W.B.6
  • 52
    • 1542317760 scopus 로고    scopus 로고
    • Interferon-dependent immunity is essential for resistance to primary dengue virus infection in mice, whereas T- and B-cell-dependent immunity are less critical
    • Shresta S., Kyle J.L., Snider H.M., Basavapatna M., Beatty P.R., and Harris E. Interferon-dependent immunity is essential for resistance to primary dengue virus infection in mice, whereas T- and B-cell-dependent immunity are less critical. J. Virol. 78 (2004) 2701-2710
    • (2004) J. Virol. , vol.78 , pp. 2701-2710
    • Shresta, S.1    Kyle, J.L.2    Snider, H.M.3    Basavapatna, M.4    Beatty, P.R.5    Harris, E.6
  • 53
    • 24744437333 scopus 로고    scopus 로고
    • Critical roles for both STAT1-dependent and STAT1-independent pathways in the control of primary dengue virus infection in mice
    • Shresta S., Sharar K.L., Prigozhin D.M., Snider H.M., Beatty P.R., and Harris E. Critical roles for both STAT1-dependent and STAT1-independent pathways in the control of primary dengue virus infection in mice. J. Immunol. 175 (2005) 3946-3954
    • (2005) J. Immunol. , vol.175 , pp. 3946-3954
    • Shresta, S.1    Sharar, K.L.2    Prigozhin, D.M.3    Snider, H.M.4    Beatty, P.R.5    Harris, E.6
  • 54
    • 33749467342 scopus 로고    scopus 로고
    • Murine model for dengue virus-induced lethal disease with increased vascular permeability
    • Shresta S., Sharar K.L., Prigozhin D.M., Beatty P.R., and Harris E. Murine model for dengue virus-induced lethal disease with increased vascular permeability. J. Virol. 80 (2006) 10208-10217
    • (2006) J. Virol. , vol.80 , pp. 10208-10217
    • Shresta, S.1    Sharar, K.L.2    Prigozhin, D.M.3    Beatty, P.R.4    Harris, E.5
  • 55
    • 33646738698 scopus 로고    scopus 로고
    • Gamma interferon plays a crucial early antiviral role in protection against West Nile virus infection
    • Shrestha B., Wang T., Samuel M.A., Whitby K., Craft J., Fikrig E., and Diamond M.S. Gamma interferon plays a crucial early antiviral role in protection against West Nile virus infection. J. Virol. 80 (2006) 5338-5348
    • (2006) J. Virol. , vol.80 , pp. 5338-5348
    • Shrestha, B.1    Wang, T.2    Samuel, M.A.3    Whitby, K.4    Craft, J.5    Fikrig, E.6    Diamond, M.S.7
  • 56
    • 0035344461 scopus 로고    scopus 로고
    • A weak signal for strong responses: interferon-alpha/beta revisited
    • Taniguchi T., and Takaoka A. A weak signal for strong responses: interferon-alpha/beta revisited. Nat. Rev., Mol. Cell Biol. 2 (2001) 378-386
    • (2001) Nat. Rev., Mol. Cell Biol. , vol.2 , pp. 378-386
    • Taniguchi, T.1    Takaoka, A.2
  • 57
    • 0031060376 scopus 로고    scopus 로고
    • Distinct organ-dependent mechanisms for the control of murine cytomegalovirus infection by natural killer cells
    • Tay C.H., and Welsh R.M. Distinct organ-dependent mechanisms for the control of murine cytomegalovirus infection by natural killer cells. J. Virol. 71 (1997) 267-275
    • (1997) J. Virol. , vol.71 , pp. 267-275
    • Tay, C.H.1    Welsh, R.M.2
  • 58
    • 0030273570 scopus 로고    scopus 로고
    • Fatal Sindbis virus infection of neonatal mice in the absence of encephalitis
    • Trgovcich J., Aronson J.F., and Johnston R.E. Fatal Sindbis virus infection of neonatal mice in the absence of encephalitis. Virology 224 (1996) 73-83
    • (1996) Virology , vol.224 , pp. 73-83
    • Trgovcich, J.1    Aronson, J.F.2    Johnston, R.E.3
  • 59
    • 0033604155 scopus 로고    scopus 로고
    • TNFalpha, interferon, and stress response induction as a function of age-related susceptibility to fatal Sindbis virus infection of mice
    • Trgovcich J., Aronson J.F., Eldridge J.C., and Johnston R.E. TNFalpha, interferon, and stress response induction as a function of age-related susceptibility to fatal Sindbis virus infection of mice. Virology 263 (1999) 339-348
    • (1999) Virology , vol.263 , pp. 339-348
    • Trgovcich, J.1    Aronson, J.F.2    Eldridge, J.C.3    Johnston, R.E.4
  • 60
    • 0035087571 scopus 로고    scopus 로고
    • Role of alpha/beta interferon in Venezuelan equine encephalitis virus pathogenesis: effect of an attenuating mutation in the 5′ untranslated region
    • White L.J., Wang J.G., Davis N.L., and Johnston R.E. Role of alpha/beta interferon in Venezuelan equine encephalitis virus pathogenesis: effect of an attenuating mutation in the 5′ untranslated region. J. Virol. 75 (2001) 3706-3718
    • (2001) J. Virol. , vol.75 , pp. 3706-3718
    • White, L.J.1    Wang, J.G.2    Davis, N.L.3    Johnston, R.E.4


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