Two-methyl-6-phenylethynyl-pyridine (MPEP), a metabotropic glutamate receptor 5 antagonist, with low doses of MK801 and diazepam: A novel approach for controlling status epilepticus

Neuropharmacology

Volumn 53, Issue 7, 2007, Pages 821-831

  Tang, Feng Ru ^a,b   Chen, Peng Min ^a   Tang, Yong Cheng ^a   Tsai, Mui Chiung ^a   Lee, Wei Ling ^a  

^a NATIONAL NEUROSCIENCE INSTITUTE   (Singapore)

^b NATIONAL UNIVERSITY OF SINGAPORE   (Singapore)

Author keywords

Group I metabotropic glutamate receptor; MPEP; Neuroprotection; Status epilepticus

Indexed keywords

1 AMINO 1,5 INDANDICARBOXYLIC ACID; 2 METHYL 6 (2 PHENYLVINYL)PYRIDINE; 2 METHYL 6 (PHENYLETHYNYL)PYRIDINE; 4 CARBOXY 2 METHYLPHENYLGLYCINE; 6 METHYL 2 PHENYLAZO 3 PYRIDINOL; DIAZEPAM; DIZOCILPINE; METABOTROPIC RECEPTOR 1; METABOTROPIC RECEPTOR 5; METABOTROPIC RECEPTOR ANTAGONIST; PILOCARPINE;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTICONVULSANT ACTIVITY; ARTICLE; CELL LOSS; CONTROLLED STUDY; DRUG DOSE COMPARISON; DRUG EFFICACY; DRUG METABOLISM; ELECTROENCEPHALOGRAM; EPILEPTIC STATE; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; HIPPOCAMPUS; INTRACTABLE EPILEPSY; LOW DRUG DOSE; MALE; MOUSE; NEUROPROTECTION; NONHUMAN; PRIORITY JOURNAL; TREATMENT RESPONSE;

ANIMALS; BEHAVIOR, ANIMAL; CHROMATOGRAPHY, HIGH PRESSURE LIQUID; DIAZEPAM; DISEASE MODELS, ANIMAL; DIZOCILPINE MALEATE; DOSE-RESPONSE RELATIONSHIP, DRUG; DRUG THERAPY, COMBINATION; ELECTROENCEPHALOGRAPHY; EXCITATORY AMINO ACID ANTAGONISTS; GABA MODULATORS; MALE; MICE; OXAZINES; PILOCARPINE; PYRIDINES; STATUS EPILEPTICUS;

EID: 35548947502     PISSN: 00283908     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.neuropharm.2007.08.012     Document Type: Article

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