Down-regulation of endogenous nitric oxide synthase inhibitors on endothelial SK3 expression

Vascular Pharmacology

Volumn 47, Issue 5-6, 2007, Pages 265-271

  Zhou, Zhi ^a   Jiang, De Jian ^a   Jia, Su Jie ^a   Xiao, Hong Bo ^a   Xiao, Bo ^b   Li, Yuan Jian ^a  

^a CENTRAL SOUTH UNIVERSITY   (China)

^b CENTRAL SOUTH UNIVERSITY   (China)

Author keywords

Asymmetric dimethylarginine; Atherosclerosis; Lysophosphatidylcholine; Small conductance calium activated channels

Indexed keywords

APOLIPOPROTEIN E; CELL PROTEIN; LYSOPHOSPHATIDYLCHOLINE; MESSENGER RNA; N(G),N(G) DIMETHYLARGININE; NITRIC OXIDE SYNTHASE; NITRIC OXIDE SYNTHASE INHIBITOR; SK3 PROTEIN; SMALL CONDUCTANCE CALCIUM ACTIVATED POTASSIUM CHANNEL; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; AORTA; ARTICLE; ATHEROSCLEROSIS; CELL CULTURE; CONCENTRATION RESPONSE; CONTROLLED STUDY; DOWN REGULATION; DRUG BLOOD LEVEL; ENDOTHELIUM CELL; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; HUMAN; HUMAN CELL; IMMUNOFLUORESCENCE; MALE; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; UMBILICAL VEIN; WESTERN BLOTTING; WILD TYPE;

ANIMALS; AORTA, THORACIC; APOLIPOPROTEINS E; ARGININE; ATHEROSCLEROSIS; CELLS, CULTURED; DOWN-REGULATION; ENDOTHELIAL CELLS; ENDOTHELIUM, VASCULAR; MALE; MICE; MICE, INBRED C57BL; MICE, KNOCKOUT; NITRIC OXIDE SYNTHASE; SMALL-CONDUCTANCE CALCIUM-ACTIVATED POTASSIUM CHANNELS; UMBILICAL VEINS;

EID: 35548938198     PISSN: 15371891     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.vph.2007.08.003     Document Type: Article

References (35)

1. Alexander S.P.H., Mathie A., and Peters J.A. Guide to Receptors and Channels (GRAC), 2nd edition (2007 revision). Br. J. Pharmacol. 150 Suppl. 1 (2007) S1-S168
2. Barriere E., Tazi K.A., Pessione F., Heller J., Poirel O., Lebrec D., and Moreau R. Role of small-conductance Ca2+-dependent K+ channels in in vitro nitric oxide-mediated aortic hyporeactivity to alpha-adrenergic vasoconstriction in rats with cirrhosis. J. Hepatol. 35 (2001) 350-357
3. Boger R.H., Bode-Boger S.M., Szuba A., Tsao P.S., Chan J.R., Tangphao O., Blaschke T.F., and Cooke J.P. Asymmetric dimethylarginine (ADMA): a novel risk factor for endothelial dysfunction: its role in hypercholesterolemia. Circulation 98 (1998) 1842-1847
4. Burnham M.P., Bychkov R., Feletou M., Richards G.R., Vanhoutte P.M., Weston A.H., and Edwards G. Characterization of an apamin-sensitive small-conductance Ca(2+)-activated K(+) channel in porcine coronary artery endothelium: relevance to EDHF. Br. J. Pharmacol. 135 (2002) 1133-1143
5. Carignani C., Roncarati R., Rimini R., and Terstappen G.C. Pharmacological and molecular characterisation of SK3 channels in the TE671 human medulloblastoma cell line. Brain Res. 939 (2002) 11-18
6. Ding H., Hashem M., Wiehler W.B., Lau W., Martin J., Reid J., and Triggle C. Endothelial dysfunction in the streptozotocin-induced diabetic apoE-deficient mouse. Br. J. Pharmacol. 146 (2005) 1110-1118
7. Eichler I., Wibawa J., Grgic I., Knorr A., Brakemeier S., Pries A.R., Hoyer J., and Kohler R. Selective blockade of endothelial Ca2+-activated small- and intermediate-conductance K+-channels suppresses EDHF-mediated vasodilation. Br. J. Pharmacol. 138 (2003) 594-601
8. Feletou M., and Vanhoutte P.M. EDHF: new therapeutic targets?. Pharmacol. Res. 49 (2004) 565-580
9. Fukao M., Hattori Y., Kanno M., Sakuma I., and Kitabatake A. Evidence for selective inhibition by lysophosphatidylcholine of acetylcholine-induced endothelium-dependent hyperpolarization and relaxation in rat mesenteric artery. Br. J. Pharmacol. 116 (1995) 1541-1543
10. Garlan C.J., and Plane F. Endothelium-derived hyperpolarizing factor (1996), Harwood Academic Publishers 173-179
11. Hasegawa K., Wakino S., Tanaka T., Kimoto M., Tatematsu S., Kanda T., Yoshioka K., Homma K., Sugano N., Kurabayashi M., Saruta T., and Hayashi K. Dimethylarginine dimethylaminohydrolase 2 increases vascular endothelial growth factor expression through Sp1 transcription factor in endothelial cells. Arterioscler. Thromb. Vasc. Biol. 26 (2006) 1488-1494
12. Hilgers R.H., and Webb R.C. Reduced expression of SKCa and IKCa Channel Proteins in Rat Small Mesenteric Arteries During Angiotensin II-Induced Hypertension. Am. J. Physiol., Heart Circ. Physiol. 292 5 (2007) H2275-H2284
13. Holden D.P., Cartwright J.E., Nussey S.S., and Whitley G.S. Estrogen stimulates dimethylarginine dimethylaminohydrolase activity and the metabolism of asymmetric dimethylarginine. Circulation 108 (2003) 1575-1580
14. Jacobson D., Pribnow D., Herson P.S., Maylie J., and Adelman J.P. Determinants contributing to estrogen-regulated expression of SK3. Biochem. Biophys. Res. Commun. 303 (2003) 660-668
15. Jia S.J., Jiang D.J., Hu C.P., Zhang X.H., Deng H.W., and Li Y.J. Lysophosphatidylcholine-induced elevation of asymmetric dimethylarginine level by the NADPH oxidase pathway in endothelial cells. Vascul. Pharmacol. 44 (2006) 143-148
16. Jiang D.J., Hu G.Y., Jiang J.L., Xiang H.L., Deng H.W., and Li Y.J. Relationship between protective effect of xanthone on endothelial cells and endogenous nitric oxide synthase inhibitors. Bioorg. Med. Chem. 11 (2003) 5171-5177
17. Jiang D.J., Jia S.J., Dai Z., and Li Y.J. Asymmetric dimethylarginine induces apoptosis via p38 MAPK/caspase-3-dependent signaling pathway in endothelial cells. J. Mol. Cell. Cardiol. 40 (2006) 529-539
18. Kohler R., Brakemeier S., Kuhn M., Behrens C., Real R., Degenhardt C., Orzechowski H.D., Pries A.R., Paul M., and Hoyer J. Impaired hyperpolarization in regenerated endothelium after balloon catheter injury. Circ. Res. 89 (2001) 174-179
19. Lin K.Y., Ito A., Asagami T., Tsao P.S., Adimoolam S., Kimoto M., Tsuji H., Reaven G.M., and Cooke J.P. Impaired nitric oxide synthase pathway in diabetes mellitus: role of asymmetric dimethylarginine and dimethylarginine dimethylaminohydrolase. Circulation 106 (2002) 987-992
20. Matsumoto T., Miyamori K., Kobayashi T., and Kamata K. Apocynin normalizes hyperreactivity to phenylephrine in mesenteric arteries from cholesterol-fed mice by improving endothelium-derived hyperpolarizing factor response. Free Radic. Biol. Med. 41 (2006) 1289-1303
21. Matsumoto T., Miyamori K., Kobayashi T., and Kamata K. Specific impairment of endothelium-derived hyperpolarizing factor-type relaxation in mesenteric arteries from streptozotocin-induced diabetic mice. Vascul. Pharmacol. 44 (2006) 450-460
22. Nakazawa T., Kaneko Y., Mori A., Saito M., Sakamoto K., Nakahara T., and Ishii K. Attenuation of nitric oxide- and prostaglandin-independent vasodilation of retinal arterioles induced by acetylcholine in streptozotocin-treated rats. Vascul. Pharmacol. 46 (2007) 153-159
23. Nolting A., Ferraro T., D'hoedt D., and Stocker M. An amino acid outside the pore region influences apamin sensitivity in small conductance Ca2+-activated K+ channels. J. Biol. Chem. 282 (2007) 3478-3486
24. Ruiz-Marcos F.M., Ortiz M.C., Fortepiani L.A., Nadal F.J., Atucha N.M., and Garcia-Estan J. Mechanisms of the increased pressor response to vasopressors in the mesenteric bed of nitric oxide-deficient hypertensive rats. Eur. J. Pharmacol. 412 (2001) 273-279
25. Sahinarslan A., Cengel A., Biberoglu G., Hasanoglu A., Turkoglu S., and Timurkaynak T. Plasma asymmetric dimethylarginine level and extent of lesion at coronary angiography. Coron. Artery Dis. 17 (2006) 605-609
26. Scalera F., Borlak J., Beckmann B., Martens-Lobenhoffer J., Thum T., Tager M., and Bode-Boger S.M. Endogenous nitric oxide synthesis inhibitor asymmetric dimethyl l-arginine accelerates endothelial cell senescence. Arterioscler. Thromb. Vasc. Biol. 24 (2004) 1816-1822
27. Suda O., Tsutsui M., Morishita T., Tasaki H., Ueno S., Nakata S., Tsujimoto T., Toyohira Y., Hayashida Y., Sasaguri Y., Ueta Y., Nakashima Y., and Yanagihara N. Asymmetric dimethylarginine produces vascular lesions in endothelial nitric oxide synthase-deficient mice: involvement of renin-angiotensin system and oxidative stress. Arterioscler. Thromb. Vasc. Biol. 24 (2004) 1682-1688
28. Tan B., Jiang D.J., Huang H., Jia S.J., Jiang J.L., Hu C.P., and Li Y.J. Taurine protects against low-density lipoprotein-induced endothelial dysfunction by the DDAH/ADMA pathway. Vascul. Pharmacol. 46 5 (2007) 338-345
29. Taylor M.S., Bonev A.D., Gross T.P., Eckman D.M., Brayden J.E., Bond C.T., Adelman J.P., and Nelson M.T. Altered expression of small-conductance Ca2+-activated K+(SK3) channels modulates arterial tone and blood pressure. Circ. Res. 93 (2003) 124-131
30. Urakami-Harasawa L., Shimokawa H., Nakashima M., Egashira K., and Takeshita A. Importance of endothelium-derived hyperpolarizing factor in human arteries. J. Clin. Invest. 100 (1997) 2793-2799
31. Valkonen V.P., Paiva H., Salonen J.T., Lakka T.A., Lehtimaki T., Laakso J., and Laaksonen R. Risk of acute coronary events and serum concentration of asymmetrical dimethylarginine. Lancet 358 (2001) 2127-2128
32. Vallance P., Leone A., Calver A., Collier J., and Moncada S. Endogenous dimethylarginine as an inhibitor of nitric oxide synthesis. J. Cardiovasc. Pharmacol. 20 Suppl. 12 (1992) S60-S62
33. Yang T.L., Chen M.F., Xia X., Luo B.L., and Li Y.J. Effect of fenofibrate on the level of asymmetric dimethylarginine in individuals with hypertriglyceridemia. Eur. J. Clin. Pharmacol. 62 (2006) 179-184
34. Yu X.J., Li Y.J., and Xiong Y. Increase of an endogenous inhibitor of nitric oxide synthesis in serum of high cholesterol fed rabbits. Life Sci. 54 (1994) 753-758
35. Zoccali C., Mallamaci F., and Tripepi G. Inflammation and atherosclerosis in end-stage renal disease. Blood Purif. 21 (2003) 29-36