Human calprotectin: Effect of calcium and zinc on its secondary and tertiary structures, and role of pH in its thermal stability

Acta Biochimica et Biophysica Sinica

Volumn 39, Issue 10, 2007, Pages 795-802

  Yousefi, Reza ^a   Imani, Mehdi ^a   Ardestani, Susan K ^a   Saboury, Ali Akbar ^a   Gheibi, Nematollah ^b   Ranjbar, Bijan ^c  

^a UNIVERSITY OF TEHRAN   (Iran)

^b QAZVIN UNIVERSITY OF MEDICAL SCIENCES   (Iran)

^c TARBIAT MODARES UNIVERSITY   (Iran)

Author keywords

Calcium; Calprotectin; Circular dichroism; Thermal stability; Zinc

Indexed keywords

CALCIUM; CALGRANULIN; ZINC;

APOPTOSIS; ARTICLE; CELL STRAIN K 562; CHEMISTRY; COMPARATIVE STUDY; DOSE RESPONSE; HEAT; HUMAN; METABOLISM; PH; PHYSIOLOGY; PROTEIN SECONDARY STRUCTURE; PROTEIN TERTIARY STRUCTURE; THERMODYNAMICS;

APOPTOSIS; CALCIUM; DOSE-RESPONSE RELATIONSHIP, DRUG; HEAT; HUMANS; HYDROGEN-ION CONCENTRATION; K562 CELLS; LEUKOCYTE L1 ANTIGEN COMPLEX; PROTEIN STRUCTURE, SECONDARY; PROTEIN STRUCTURE, TERTIARY; THERMODYNAMICS; ZINC;

EID: 35449004112     PISSN: 16729145     EISSN: 17457270     Source Type: Journal    
DOI: 10.1111/j.1745-7270.2007.00343.x     Document Type: Article

References (43)

1. Bhardwaj RS, Zotz C, Zwadlo-Klarwasser G, Roth J, Goebeler M, Mahnke K, Falk M et al. The calcium-binding proteins MRP8 and MRP14 form a membrane-associated heterodimer in a subset of monocytes/macrophages present in acute but absent in chronic inflammatory lesions. Eur J Immunol 1992 22 : 1891 1897.
2. 2+-binding proteins of neutrophils and monocytes. J Leukoc Biol 1993 53 : 197 204.
3. Andersson KB, Sletten K, Berntzen HB, Dale I, Brandtzaeg P, Jellum E, Fagerhol MK. The leucocyte L1 protein: Identity with the cystic fibrosis antigen and the calcium-binding MRP-8 and MRP-14 macrophage components. Scand J Immunol 1988 28 : 241 245.
4. Hogg N, Allen C, Edgeworth J. Monoclonal antibody 5.5 reacts with p8, 14, a myeloid molecule associated with some vascular endothelium. Eur J Immunol 1989 19 : 1053 1061.
5. Wilkinson MM, Busuttil A, Hayward C, Brock DJ, Dorin JR, Van Heyningen V. Expression pattern of two related cystic fibrosis-associated calcium-binding proteins in normal and abnormal tissues. J Cell Sci 1988 91 : 221 230.
6. Nacken W, Roth J, Sorg C, Kerkhoff C. S100A9/S100A8: Myeloid representatives of the S100 protein family as prominent players in innate immunity. Microsc Res Tech 2003 60 : 569 580.
7. Heizmann CW, Hunziker W. Intracellular calcium-binding proteins: More sites than insights. Trends Biochem Sci 1991 16 : 98 103.
8. Burgess WH, Jemiolo DK, Kretsinger RH. Interaction of calcium and calmodulin in the presence of sodium dodecyl sulfate. Biochim Biophys Acta 1980 623 : 257 270.
9. Loomans HJ, Hahn BL, Li QQ, Phadnis SH, Sohnle PG. Histidine-based zinc-binding sequences and the antimicrobial activity of calprotectin. J Infect Dis 1998 177 : 812 814.
10. Sohnle PG, Hunter MJ, Hahn B, Chazin WJ. Zinc-reversible antimicrobial activity of reacombinant calprotectin (migration inhibitory factor-related proteins 8 and 14). J Infect Dis 2000 182 : 1272 1275.
11. Yui S, Mikami M, Tsurumaki K, Yamazaki M. Growth-inhibitory and apoptosis-inducing activities of calprotectin derived from inflammatory exu-date cells on normal fibroblasts: Regulation by metal ions. J Leukoc Biol 1997 61 : 50 57.
12. Yui S, Mikami M, Yamazaki M. Induction of apoptotic cell death in mouse lymphoma and human leukemia cell lines by a calcium-binding protein complex, calprotectin, derived from inflammatory peritoneal exudate cells. J Leukoc Biol 1995 58 : 650 658.
13. Berntzen HB, Olmez U, Fagerhol MK, Munthe E. The leukocyte protein L1 in plasma and synovial fluid from patients with rheumatoid arthritis and osteoarthritis. Scand J Rheumatol 1991 20 : 74 82.
14. Isaksen B, Fagerhol MK. Calprotectin inhibits matrix metalloproteinases by sequestration of zinc. Mol Pathol 2001 54 : 289 292.
15. Kerkhoff C, Klempt M, Kaever V, Sorg C. The two calcium-binding proteins, S100A8 and S100A9, are involved in the metabolism of arachidonic acid in human neutrophils. J Biol Chem 1999 274 : 32672 32679.
16. 2+-binding proteins MRP8 and MRP14 binds to arachidonic acid. FEBS Lett 1997 408 : 81 84.
17. Striz I, Trebichavsky I. Calprotectin - a pleiotropic molecule in acute and chronic inflammation. Physiol Res 2004 53 : 245253.
18. Donato R. Functional roles of S100 proteins, calcium-binding proteins of the EF-hand type. Biochim Biophys Acta 1999 1450 : 191 231.
19. Groves P, Finn BE, Kuznicki J, Forsen S. A model for target protein binding to calcium-activated S100 dimers. FEBS Lett 1998 421 : 175 179.
20. Tugizov S, Berline J, Herrera R, Penaranda ME, Nakagawa M, Palefsky J. Inhibition of human papillomavirus type 16 E7 phosphorylation by the S100 MRP-8/14 protein complex. J Virol 2005 79 : 1099 1012.
21. Murao S, Collart FR, Huberman E. A protein containing the cystic fibrosis antigen is an inhibitor of protein kinases. J Biol Chem 1989 264 : 83568360.
22. Roseth AG, Kristinsson J, Fagerhol MK, Schjonsby H, Aadland E, Nygaard K, Roald B. Faecal calprotectin: A novel test for the diagnosis of colorectal cancer. Scand J Gastroenterol 1993 28 : 1073 1076.
23. Skoog WA, Beck WS. Studies on the fibrinogen, dextran and phytohemag-glutinin methods of isolating leukocytes. Blood 1956 11 : 436 454.
24. Yui S, Mikami M, Yamazaki M. Purification and characterization of the cytotoxic factor in rat peritoneal exudate cells: Its identification as the calcium binding protein complex, calprotectin. J Leukoc Biol 1995 58 : 307 316.
25. Schagger, H, Von Jagow, G. Tricine-sodium dodecyl sulfate-polyacrylamide gel electrophoresis for the separation of proteins in the range from 1 to 100 kDa. Anal Biochem 1987 166 : 368 379.
26. Crestfield AM, Moore S, Stein WH. The preparation and enzymatic hydrolysis of reduced and S-carboxymethylated proteins. J Biol Chem 1963 238 : 622 627.
27. Mosmann T. Rapid colorimetric assay for cellular growth and survival: Application to proliferation and cytotoxicity assays. J Immunol Methods 1983 65 : 55 63.
28. Kelly SM, Price NC. The use of circular dichroism in the investigation of protein structure and function. Curr Protein Pept Sci 2000 1 : 349 384.
29. Viseu MI, Carvalho TI, Costa SM. Conformational transitions in beta-lactoglobulin induced by cationic amphiphiles: Equilibrium studies. Biophys J 2004 86 : 2392 2402.
30. Kerkhoff C, Klempt M, Sorg C. Novel insights into structure and function of MRP8 (S100A8) and MRP14 (S100A9). Biochim Biophys Acta 1998 1448 : 200 211.
31. Pace CN. Measuring and increasing protein stability. Trends Biotechnol 1990 8 : 93 98.
32. Pace CN, Shirley BA, Thomson JA. Chapter 13. In : Creighton, TE, ed. Protein Structure: A Practical Approach. Oxford : IRL Press, 1990.
33. Pace CN, Trevino S, Prabhakaran E, Scholtz JM. Protein structure, stability and solubility in water and other solvents. Philos Trans R Soc Lond B Biol Sci 2004 359 : 1225 1234.
34. Saboury AA, Karbassi F. Thermodynamic studies on the interaction of calcium ions with alpha-amylase. Thermochim Acta 2000 362 : 121 129.
35. Yui S, Nakatani Y, Mikami M. Calprotectin (S100A8/S100A9), an inflammatory protein complex from neutrophils with a broad apoptosis-inducing activity. Biol Pharm Bull 2003 26 : 753 760.
36. Versieck J, Cornelis R. Normal levels of trace elements in human blood, plasma, or serum. Anal Chim Acta 1980 116 : 217 254.
37. Naess-Andresen CF, Egelandsdal B, Fagerhol MK. Calcium binding and concomitant changes in the structure and heat stability of calprotectin (L1 protein). Clin Mol Pathol 1995 48 : M278 M284.
38. Yousefi R, Ardestani SK, Saboury AA, Kariminia A, Zeinali M, Amani M. Investigation on the surface hydrophobicity and aggregation kinetics of human calprotectin in the presence of calcium. J Biochem Mol Biol 2005 38 : 407 413.
39. Akiyama H, Ikeda K, Katoh M, McGeer EG, McGeer PL. Expression of MRP14, 27E10, interferon-alpha and leukocyte common antigen by reactive microglia in postmortem human brain tissue. J Neuroimmunol 1994 50 : 195 201.
40. Bernstein SL, Wyttenbach T, Baumketner A, Shea JE, Bitan G, Teplow DB, Bowers MT. Amyloid beta-protein: Monomer structure and early aggregation states of Abeta42 and its Pro19 alloform. J Am Chem Soc 2005 127 : 2075 2084.
41. Hope J, Shearman MS, Baxter HC, Chong A, Kelly SM, Price NC. Cyto-toxicity of prion protein peptide (PrP106-126) differs in mechanism from the cytotoxic activity of the Alzheimer's disease amyloid peptide, A beta 25-35. Neurodegeneration 1996 5 : 1 11.
42. Stefani M, Dobson CM. Protein aggregation and aggregate toxicity: New insights into protein folding, misfolding diseases and biological evolution. J Mol Med 2003 81 : 678 699.
43. Kerkhoff C, Vogl T, Nacken W, Sopalla C, Sorg C. Zinc binding reverses the calcium-induced arachidonic acid-binding capacity of the S100A8/A9 protein complex. FEBS Lett 1999 460 : 134 138.