Histopathologic and Immunologic Aspects of AlphaCor Artificial Corneal Failure

American Journal of Ophthalmology

Volumn 144, Issue 5, 2007, Pages

  Coassin, Marco ^a,b   Zhang, Cheng ^a   Green, W Richard ^a   Aquavella, James V ^c   Akpek, Esen K ^a  

^a JOHNS HOPKINS UNIVERSITY   (United States)

^b UNIVERSITY CAMPUS BIO MEDICO   (Italy)

^c UNIVERSITY OF ROCHESTER   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CD34 ANTIGEN; GAMMA INTERFERON; INTERLEUKIN 1BETA; SMOOTH MUSCLE ACTIN; THY 1 ANTIGEN; TUMOR NECROSIS FACTOR ALPHA;

ADULT; AGED; ARTICLE; CASE REPORT; CELL DIFFERENTIATION; CLINICAL ASSESSMENT; CLINICAL EXAMINATION; CORNEA; CORNEA CELL; CYTOKINE RELEASE; DEVICE REMOVAL; ELECTRON MICROSCOPY; FEMALE; HISTOPATHOLOGY; HUMAN; IMMUNOFLUORESCENCE; IMMUNOHISTOCHEMISTRY; IMMUNOREACTIVITY; KERATOPROSTHESIS; LENS IMPLANT; LENS IMPLANTATION; MALE; MICROSCOPY; MYOFIBROBLAST; POSTOPERATIVE PERIOD; PRIORITY JOURNAL;

EID: 35448992495     PISSN: 00029394     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.ajo.2007.07.025     Document Type: Article

References (17)

1. Hicks C., Crawford G., Chirila T., et al. Development and clinical assessment of an artificial cornea. Prog Ret Eye Res 19 (2000) 149-170
2. Hicks C.R., Werner L., Vijayasekaran S., Mamalis N., and Apple D.J. Histology of AlphaCor skirts: evaluation of biointegration. Cornea 24 (2005) 933-940
3. Hicks C.R., Crawford G.J., Lou X., et al. Corneal replacement using a synthetic hydrogel cornea, AlphaCor: device, preliminary outcomes and complications. Eye 17 (2003) 385-392
4. Dana M.R., Qian Y., and Hamrah P. Twenty-five-year panorama of corneal immunology: emerging concepts in the immunopathogenesis of microbial keratitis, peripheral ulcerative keratitis, and corneal transplant rejection. Cornea 19 (2000) 625-643
5. Crawford G.J., Hicks C.R., Lou X., et al. The chirila keratoprosthesis: phase I human clinical trial. Ophthalmology 109 (2002) 883-889
6. Hicks C.R., and Crawford G.J. Melting after keratoprosthesis implantation: the effects of medroxyprogesterone. Cornea 22 (2003) 497-500
7. Ilhan-Sarac O., and Akpek E.K. Current concepts and techniques in keratoprosthesis. Curr Opin Ophthalmol 16 (2005) 246-250
8. Hick C.R., Crawford G.J., Dart J.K., et al. AlphaCor: clinical outcomes. Cornea 25 (2006) 1034-1042
9. Fitton J.H., Ziegelaar B.W., Hicks C.R., et al. Assessment of anticollagenase treatments after insertion of a keratoprosthetic material in the rabbit cornea. Cornea 17 (1998) 108-114
10. Henniker A.J. CD90. J Biol Regul Homeost Agents 15 (2001) 392-393
11. Koumas L., King A.E., Critchley H.O., Kelly R.W., and Phipps R.P. Fibroblast heterogeneity: existence of functionally distinct Thy 1(+) and Thy 1(-) human female reproductive tract fibroblasts. Am J Pathol 159 (2001) 925-935
12. Pei Y., Sherry D.M., and McDermott A.M. Thy-1 distinguishes human corneal fibroblasts and myofibroblasts from keratocytes. Exp Eye Res 79 (2004) 705-712
13. Jester J.V., Barry-Lane P.A., Cavanagh H.D., and Petroll W.M. Induction of alpha-smooth muscle actin expression and myofibroblast transformation in cultured corneal keratocytes. Cornea 15 (1996) 505-516
14. Toti P., Tosi G.M., Traversi C., Schurfeld K., Cardone C., and Caporossi A. CD-34 stromal expression pattern in normal and altered human corneas. Ophthalmology 109 (2002) 1167-1171
15. Zhu S., Dekaris I., Duncker M., and Dana M.R. Early expression of proinflammatory cytokines interleukin-1 and tumor necrosis factor-alpha after corneal transplantation. J Interferon Cytokine Res 19 (1999) 661-669
16. Hong J.W., Liu J.J., Lee J.S., et al. Proinflammatory chemokine induction in keratocytes and inflammatory cell infiltration into the cornea. Invest Ophthalmol Vis Sci 42 (2001) 2795-2803
17. Nakamura K. Interaction between injured corneal epithelial cells and stromal cells. Cornea 22 (2003) S35-S47