Cocaine-induced relaxation of isolated rat aortic rings and mechanisms of action: Possible relation to cocaine-induced aortic dissection and hypotension

European Journal of Pharmacology

Volumn 496, Issue 1, 2004, Pages 151-158

  Li, Wenyan ^a   Su, Jialin ^a   Sehgal, Swati ^a   Altura, Bella T ^a,b   Altura, Burton M ^a,b  

^a SUNY DOWNSTATE MEDICAL CENTER   (United States)

^b SUNY Downstate Medical Center   (United States)

Author keywords

Aortic dissection; Aortic ring; Ca2+ entry; Cocaine; Phosphatase; Relaxation

Indexed keywords

ANTIOXIDANT; ARGININE; BETA ADRENERGIC RECEPTOR BLOCKING AGENT; CALYCULIN A; CIMETIDINE; COCAINE; CYCLIC GMP DEPENDENT PROTEIN KINASE INHIBITOR; CYCLIC GMP DERIVATIVE; CYCLIC GMP TRIETHYLAMINE; CYCLOOXYGENASE 1 INHIBITOR; DIPHENHYDRAMINE; DOPAMINE 1 RECEPTOR BLOCKING AGENT; ENZYME INHIBITOR; HALOPERIDOL; HISTAMINE H1 RECEPTOR ANTAGONIST; HISTAMINE H2 RECEPTOR ANTAGONIST; INDOMETACIN; KT 5823; METHYLENE BLUE; METHYSERGIDE; MYOSIN LIGHT CHAIN KINASE INHIBITOR; MYOSIN LIGHT CHAIN PHOSPHATASE; N(G) METHYLARGININE; PHENYLEPHRINE; PROPRANOLOL; SEROTONIN 1 ANTAGONIST; SQ 22538; UNCLASSIFIED DRUG; UNINDEXED DRUG; VASOACTIVE AGENT;

AORTA DISSECTION; ARTERY DILATATION; ARTERY MUSCLE; ARTICLE; CONCENTRATION RESPONSE; ENDOTHELIUM CELL; ENZYME ACTIVATION; HYPOTENSION; MALE; NONHUMAN; PRIORITY JOURNAL; RAT; SMOOTH MUSCLE FIBER; VASCULAR RING; VASCULAR SMOOTH MUSCLE; VASOCONSTRICTION;

ANEURYSM, DISSECTING; ANIMALS; AORTA, THORACIC; AORTIC ANEURYSM, THORACIC; COCAINE; DOSE-RESPONSE RELATIONSHIP, DRUG; HYPOTENSION; MALE; RATS; RATS, WISTAR; VASODILATION;

EID: 3543106192     PISSN: 00142999     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.ejphar.2004.06.015     Document Type: Article

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