Packaging principle: How DNA methylation and histone acetylation control the transcriptional activity of chromatin

Journal of Experimental Zoology

Volumn 282, Issue 1-2, 1998, Pages 239-244

  Wolffe, Alan P ^a  

^a EUNICE KENNEDY SHRIVER NATIONAL INSTITUTE OF CHILD HEALTH AND HUMAN DEVELOPMENT   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ACETYLATION; CHROMATIN; DNA METHYLATION; PROMOTER REGION; TRANSCRIPTION REGULATION;

VERTEBRATA;

EID: 3543035174     PISSN: 0022104X     EISSN: None     Source Type: Journal    
DOI: 10.1002/(sici)1097-010x(199809/10)282:1/2<239::aid-jez25>3.0.co;2-n     Document Type: Article

References (42)

1. Almouzni, G., S. Khochbin, S. Dimitrov, and A.P. Wolffe (1994) Histone acetylation influences both gene expression and development of Xenopus laevis. Dev. Biol., 165:654-669.
2. Antequera, F., D. McLeod, and A. Bird (1989) Specific protection of methylated CpGs in mammalian nuclei. Cell, 58:509-517.
3. Bird, A. (1995) Gene number, noise reduction and biological complexity. Trends Genet., 11:94-100.
4. Braunstein, M., A.B. Rose, S.G. Holmes, C.D. Allis, and J.R. Broach (1993) Transcriptional silencing in yeast in associated with reduced histone acetylation. Genes Dev., 7:592-604.
5. Brownell, J.E., J. Zhou, T. Ranalli, R. Kobayashi, D.G. Edmondson, S.Y. Roth, and C.D. Allis (1996) Tetrahymena histone acetyltransferase A: A homolog to yeast Gcn5p linking histone acetylation to gene activation. Cell, 84:843-851.
6. Buschhausen, G., B. Wittig, M. Graessmann, and A. Graessmann (1987) Chromatin structure is required to block transcription of the methylated herpes simplex virus thymidine kinase gene. Proc. Natl. Acad. Sci. USA, 84:1177-1181.
7. Cusick, M.E., K.S. Lee, M.L. DePamphilis, and P.M. Wasserman (1983) Structure of chromatin at deoxyribonucleic acid replication forks: nuclease hypersensitivity results from both prenucleosomal deoxyribonucleic acid and an immature chromatin structure. Biochemistry, 22:3873-3884.
8. Felsenfeld, G., J. Nickol, M. Behe, J. McGhee, and D. Jackson (1983) Methylation and chromatin structure. Cold Spring Harbor Symp. Quant. Biol., 47:577-584.
9. Godde, J.S., S.U. Kass, M.C. Hirst, and A.P. Wolffe (1996) Nucleosome assembly on methylated CGG triplet repeats in the fragile X mental retardation gene 1 promoter. J. Biol. Chem., 271:24325-24328.
10. Hebbes, T.R., A.L. Clayton, A.W. Thorne, and C. Crane-Robinson (1994) Core histone hyperacetylation co-maps with generalized DNase I sensitivity in the chicken β-globin chromosomal domain. EMBO J., 13:1823-1830.
11. Hong, L., G.P. Schroth, H.R. Matthews, P. Yau, and E.M. Bradbury (1993) Studies of the DNA binding properties of the histone H4 amino terminus. J. Biol. Chem., 268:305-314.
12. Hsieh, C.-L. (1994) Dependence of transcriptional repression on CpG methylation density. Mol. Cell. Biol., 14:5487-5494.
13. Imhof, A., X.J. Yang, V.V. Ogryzko, Y. Nakatani, A.P. Wolffe, and H. Ge (in press) Acetylation of general transcription factors by histone acetyltransferases: identification of a major site of acetylation in TFIIE. Curr. Biol. 7:689-692.
14. Jeppesen, P. (1997) Histone acetylation: a possible mechanism for the inheritance of cell memory at mitosis. Bioessays 19:67-74.
15. Jeppesen, P., and B.M. Turner (1993) The inactive X chromosome in female mammals is distinguished by a lack of histone H4 acetylation, a cytogenetic marker for gene expression. Cell, 74:281-291.
16. Jones, P.L., G.J.C. Veenstra, P.A. Wade, D. Vermaak, S.U. Kass, N. Landsberger, J. Strouboulis, and A.P. Wolffe (1998) Methylated DNA and MecP2 recruit histone deacetylase to repress transcription. Nature Genet., (in press).
17. Kass, S.U., N. Landsberger, and A.P. Wolffe (1997) DNA methylation directs a time-dependent repression of transcription initiation. Curr. Biol., 7:157-165.
18. Keshet, I., J. Lieman-Hurwitz, and H. Cedar ( 1986) DNA methylation affects the formation of active chromatin. Cell, 44:535-543.
19. Landsberger, N., and A.P. Wolffe (1995) The role of chromatin and Xenopus heat shock transcription factor (XHSF1) in the regulation of the Xenopus hsp70 promoter in vivo. Mol. Cell. Biol., 15:6013-6024.
20. Lee, D.Y., J.J. Hayes, D. Pruss, and A.P. Wolffe (1993) A positive role for histone acetylation in transcription factor binding to nucleosomal DNA. Cell, 72:73-84.
21. Lei, H., S.P. Oh, M. Okano, R. Juttermann, K.A. Goss, R. Jaenisch, and E. Li (1996) De novo DNA cytosine methyltransferase activities in mouse embryonic stem cells. Development, 122:3195-3205.
22. Leonhardt, H., A.W. Page, H.-U. Weier, and T.H. Bestor ( 1992) A targeting sequence directs DNA methyltransferase to sites of DNA replication in mammalian nuclei. Cell, 71:865-873.
23. McArthur, M., and J.O. Thomas (1996) A preference of histone H1 for methylated DNA. EMBO J., 15:1705-1714.
24. Meehan, R.R., J.D. Lewis, and A.P. Bird (1992) Characterization of MeCP2, a vertebrate DNA binding protein with affinity for methylated DNA. Nucleic Acids Res., 20:5085-5092.
25. II250 subunit of TFIID has histone acetyltransferase activity. Cell, 87:1261-1270.
26. Nacheva, G.A., D.Y. Guschin, O.V. Preobrazhenskaya, V.L. Karpov, K.K. Elbradise, and A.D. Mirzabekov (1989). Change in the pattern of histone binding to DNA upon transcriptional activation. Cell, 58:27-36.
27. Nan, X., J. Campoy, and A. Bird (1997) MeCP2 is a transcriptional repressor with abundant binding sites in genomic chromatin. Cell, 88:1-11.
28. Nightingale, K. and A.P. Wolffe (1995) Methylation at CpG sequences does not influence histone H1 binding to a nucleosome including a Xenopus borealis 5S rRNA gene. J. Biol. Chem., 270:4197-4200.
29. Ogryzko, V.V., R.L. Schiltz, V. Russanova, B.H. Howard, and Y. Nakatani (1996) The transcriptional coactivators p300 and CBP are histone acetyltransferases. Cell, 87:953-959.
30. Perry, C.A., C.D. Allis, and A.T. Annunziato (1993) Parental nucleosomes segregated to newly replicated chromatin are underacetylated relative to those assembled de novo. Biochemistry, 32:13615-13623.
31. Pruss, D., J.J. Hayes, and A.P. Wolffe (1995) Nucleosomal anatomy: where are the histones? Bioessays, 17:161-170.
32. Reik, W., and M.A. Surani (1989) Genomic imprinting and embryonal tumors. Nature, 338:112-113.
33. Taunton, J., C.A. Hassig, and S.L. Schreiber (1996) A mammalian histone deacetylase related to a yeast transcriptional regulator Rpd3. Science, 272:408-411.
34. Tazi, J., and A. Bird (1990) Alternative chromatin structure at CpG islands. Cell, 60:902-920.
35. Ura, K., H. Kurumizaka, S. Dimitrov, G. Almouzni, and A.P. Wolffe (1997) Histone acetylation: influence on transcription by RNA polymerase, nucleosome mobility and positioning, and linker histone dependent transcriptional repression. EMBO J., 16:2096-2107.
36. Van Holde, K.E. (1988) Chromatin. Springer-Verlag, New York.
37. Vettesse-Dadey, M., P.A. Grant, T.R. Hebbes, C. Crane-Robinson, C.D. Allis, and J.L. Workman (1996) Acetylation of histone H4 plays a primary role in enhancing transcription factor binding to nucleosomal DNA in vitro. EMBO J., 15:2508-2518.
38. Wolffe, A.P. (1996) Histone deacetylase: a regulator of transcription. Science, 272:371-372.
39. Wolffe, A.P. (1997) Sinful repression. Nature, 357:16-17.
40. Wolffe, A.P., and D. Pruss (1996) Targeting chromatin disruption: transcription factors that acetylate histones. Cell, 84:817-819.
41. Worcel, A., S. Han, and M.L. Wong (1978) Assembly of newly replicated chromatin. Cell, 15:969-977.
42. Yoshida, M., S. Horinouoshi, and T. Beppu (1995) Trichostatin A and trapoxin: novel chemical probes for the role of histone acetylation in chromatin structure and function. Bioessays, 17:423-430.