Reduction of human anti-tetanus toxoid antibody in hu-PBL-SCID mice by immunodominant peptides of tetanus toxoid

Clinical and Experimental Immunology

Volumn 137, Issue 2, 2004, Pages 245-252

  Jackson, D J ^a,b   Elson, C J ^a   Kumpel, B M ^a  

^a UNIVERSITY OF BRISTOL   (United Kingdom)

^b NHS BLOOD AND TRANSPLANT   (United Kingdom)

Author keywords

Anti tetanus toxoid; hu PBL SCID; IgG; Peptides; SCID; Tetanus toxoid

Indexed keywords

EPITOPE; GLUTAMINYLTYROSYLISOLEUCYLLYSYLALANYLASPARAGINYLSERYLLYSYLPHENYLALANYL ISOLEUCYLGLYCYLISOLEUCYLTHREONYLGLUTAMYLLEUCINE; GLYCYLGLUTAMINYLISOLEUCYLGLYCYLASPARAGINYLASPARTYLPROLYLASPARAGINYLARGINYL ASPARTYLISOLEUCYLLEUCINE; IMMUNOGLOBULIN G; PEPTIDE DERIVATIVE; PHENYLALANYLASPARAGINYLASPARAGINYLPHENYLALANYLTHREONYLVALYLSERYL PHENYLALANYLTRYPTOPHYLLEUCYLARGINYLVALYLPROLYLLYSYLVALYLSERYLALANYLSERYL HISTIDYLLEUCYLGLUTAMIC ACID; TETANUS TOXOID; TOXIN ANTIBODY; UNCLASSIFIED DRUG;

ADULT; ALLERGIC DISEASE; ANIMAL EXPERIMENT; ANTIBODY RESPONSE; ARTICLE; AUTOIMMUNE DISEASE; CELL PROLIFERATION; CONCENTRATION (PARAMETERS); CONTROLLED STUDY; HUMAN; HUMAN CELL; IMMUNE DEFICIENCY; IMMUNIZATION; IMMUNOTHERAPY; LEUKOCYTE; MOUSE; NATURAL KILLER CELL; NONHUMAN; NORMAL HUMAN; PRIORITY JOURNAL; STATISTICAL SIGNIFICANCE; T LYMPHOCYTE;

ADULT; ANIMALS; CELLS, CULTURED; CYTOKINES; EPITOPES, T-LYMPHOCYTE; HUMANS; IMMUNODOMINANT EPITOPES; IMMUNOGLOBULIN G; IMMUNOSUPPRESSION; LEUKOCYTE TRANSFUSION; MICE; MICE, SCID; MIDDLE AGED; TETANUS TOXOID;

EID: 3543026932     PISSN: 00099104     EISSN: None     Source Type: Journal    
DOI: 10.1111/j.1365-2249.2004.02521.x     Document Type: Article

References (48)

1. Kumpel BM, Elson CJ. Mechanism of anti-D-mediated immune suppression - a paradox awaiting resolution? Trends Immunol 2001; 22:26-31.
2. Kaplan C. Alloimmune thrombocytopenia of the fetus and newborn. Blood Rev 2002; 16:69-72.
3. Morales WJ, Stroup M. Intracranial hemorrhage in utero due to isoimmune neonatal thrombocytopenia. Obstet Gynecol 1985; 65:20S-21S.
4. a) as determined by antenatal screening. Blood 1998; 92:2280-7.
5. Schiffer CA. Diagnosis and management of refractoriness to platelet transfusion. Blood Rev 2001; 15:175-80.
6. van Kampen CA, Roelen DL, Versteeg-van der Voort Maarschalk MF, Hoitsma AJ, Allebes WA, Claas FH. Activated HLA class I-reactive cytotoxic T lymphocytes associated with a positive historical cross-match predict early graft failure. Transplantation 2002; 74:1114-9.
7. Lee PC, Terasaki PI, Takemoto SK, Lee PH, Hung CJ, Chen YL, Tsai A, Lei HY. All chronic rejection failures of kidney transplants were preceded by the development of HLA antibodies. Transplantation 2002; 74:1192-4.
8. Joosten SA, van Kooten C, Paul LC. Pathogenesis of chronic graft rejection. Transpl Int 2003; 16:137-45.
9. Dwyer JM. Manipulating the immune system with immune globulin. New Engl J Med 1992; 326:107-16.
10. John R, Lietz K, Burke E et al. Intravenous immunoglobulin reduces anti-HLA alloreactivity and shortens waiting time to cardiac transplantation in highly sensitized left ventricular assist device recipients. Circulation 1999; 100 (19 Suppl.): II229-35.
11. Bussel JB. Novel approaches to refractory immune thrombocytopenic purpura. Blood Rev 2002; 16:31-6.
12. Rosse WF. Clinical management of adult ITP prior to splenectomy: a perspective. Blood Rev 2002; 16:47-9.
13. Metzler B, Wraith DC. Inhibition of experimental autoimmune encephalomyelitis by inhalation but not oral administration of the encephalitogenic peptide: influence of MHC binding affinity. Int Immunol 1993; 5:1159-65.
14. Burkhart C, Liu GY, Anderton SM, Metzler B, Wraith DC. Peptide-induced T cell regulation of experimental autoimmune encephalomyelitis: a role for IL-10. Int Immunol 1999; 11:1625-34.
15. Tian J, Atkinson MA, Clare-Salzer M, Herschenfeld A, Forsthuber T, Lehmann PV, Kaufman DL. Nasal administration of glutamate decarboxylase (GAD65) peptides induces Th2 responses and prevents murine insulin-dependent diabetes. J Exp Med 1996; 183:1561-7.
16. Daniel D, Wegmann DR. Protection of nonobese diabetic mice from diabetes by intranasal or subcutaneous administration of insulin peptide B-(9-23). Proc Natl Acad Sci USA 1996: 93:956-60.
17. Karachunski PI, Ostlie NS, Okita DK, Conti-Fine BM. Prevention of experimental myasthenia gravis by nasal administration of synthetic acetylcholine receptor T epitope sequences. J Clin Invest 1997; 100:3027-35.
18. Shen CR, Youssef R, Devine A, Bowie L, Hall AM, Wraith DC, Elson CJ, Barker RN. Peptides containing a dominant T-cell epitope from red cell Band 3 have in vivo immunomodulatory properties in NZB mice with autoimmune hemolytic anemia. Blood: 2003; 102:3800-6.
19. Hoyne GF, O'Hehir RE, Wraith DC, Thomas WR, Lamb JR. Inhibition of T cell and antibody responses to house dust mite allergen by inhalation of the dominant T cell epitope in naïve and sensitized mice. J Exp Med 1993; 178:1783-8.
20. Mosier DE, Gulizia RJ, Baird SM, Wilson DB. Transfer of a functional human immune system to mice with severe combined immunodeficiency. Nature 1988; 335:256-9.
21. Kumpel BM, Poole GD, Jackson DJ. Specific anti-A responses of SCID mice populated with human lymphoid cells from peripheral blood, umbilical cord, bone marrow and spleen after immunization with group A erythrocytes. Immunol Lett 1992; 33:163-8.
22. Leader KA, Macht LM, Steers F, Kumpel BM, Elson CJ. Antibody responses to the blood group antigen D in SCID mice reconstituted with human blood mononuclear cells. Immunology 1992; 76:229-34.
23. Jackson DJ, Kumpel BM. Optimisation of human anti-tetanus toxoid antibody responses and location of human cells in SCID mice transplanted with human peripheral blood leucocytes. Hum Antibod 1997; 8:181-8.
24. Demotz S, Matricardi PM, Irle C, Panina P, Lanzavecchia A, Corradin G. Processing of tetanus toxin by human antigen-presenting cells. Evidence for donor and epitope-specific processing pathways. J Immunol 1989; 143:3881-6.
25. Demotz S, Lanzavecchia A, Eisel U, Niemann H, Widmann C, Corradin G. Delineation of several DR-restricted tetanus toxin T cell epitopes. J Immunol 1989; 142:394-402.
26. Panina-Bordignon P, Tan A, Termijtelen A, Demotz S, Corradin G, Lanzavecchia A. Universally immunogenic T cell epitopes: promiscuous binding to human MHC class II and promiscuous recognition by T cells. Eur J Immunol 1989; 19:2237-42.
27. Plebanski M, Burtles SS. In vitro primary responses of humanT cells to soluble protein antigens. J Imm Meths 1994; 170:15-25.
28. Kumpel BM. A simple non-isotopic method for the quantitation of red cell-bound immunoglobulin. Vox Sang 1990; 59:34-8.
29. Habu S, Fukui H, Shimamura K, Kasai M, Nagai Y, Okumura K, Tamaoki N. In vivo effects of anti-asialo GM1. I. Reduction of NK activity and enhancement of transplanted tumor growth in nude mice. J Immunol 1981; 127:34-8.
30. - volunteers. Blood 1995: 86:1701-9.
31. Berney T, Molano RD, Pileggi A, Cattan P, Li H, Ricordi C, Inverardi L. Patterns of engraftment in different strains of immunodeficient mice reconstituted with human peripheral blood lymphocytes. Transplantation 2001; 72:133-40.
32. Tournoy KG, Depraetere S, Pauwels RA, Leroux-Roels GG. Mouse strain and conditioning regimen determine survival and function of human leucocytes in immunodeficient mice. Clin Exp Immunol 2000; 119:231-9.
33. Abedi MR, Christensson B, Islam KB, Hammarstrom L, Smith CI. Immunoglobulin production in severe combined immunodeficient (SCID) mice reconstituted with human peripheral blood mononuclear cells. Eur J Immunol 1992; 22:823-8.
34. Macht LM, Corrall RJ, Banga JP, Elson CJ. Control of human thyroid autoantibody production in SCID mice. Clin Exp Immunol 1993; 91:390-6.
35. Wang ZY, Karachunski PI, Howard JF Jr, Conti-Fine BM. Myasthenia in SCID mice grafted with myasthenic patient lymphocytes: role of CD4+ and CD8+ cells. Neurol 1999; 52:484-97.
36. Lazarus AH, Crow AR, Freedman J, Blanchette V, Hannach B. Inhibition of a secondary human alloimmune response via the soluble active component of CD154 (CD40L) in severe combined immunedeficient mice engrafted with human lymphocytes. Transfusion 1999; 39:818-23.
37. Massey EJ, Sundstedt A, Day MJ, Corfield G, Anderton S, Wraith DC. Intranasal peptide- induced peripheral tolerance: the role of IL-10 in regulatory T cell function within the context of experimental autoimmune encephalomyelitis. Vet Immunol Immunopath 2002; 87:357-72.
38. Sundstedt A, O'Neill EJ, Nicolson KS, Wraith DC. Role for IL-10 in suppression mediated by peptide-induced regulatory cells in vivo. J Immunol 2003; 170:1240-8.
39. + T cells with regulatory properties by repetitive stimulation with allogeneic immature human dendritic cells. J Exp Med 2000; 192:1213-22.
40. Dhodapkar MV, Steinman RM, Krasovsky J, Munz C, Bhardwaj N. Antigen-specific inhibition of effector T cell function in humans after injection of immature dendritic cells. J Exp Med 2001; 193:233-8.
41. Santambrogio L, Sato AK, Fischer FR, Dorf ME, Stern LJ. Abundant empty class II MHC molecules on the surface of immature dendritic cells. Proc Natl Acad Sci USA 1999; 96:15050-5.
42. Lanzavecchia A, Reid PA, Watts C. Irreversible association of peptides with class II MHC molecules in living cells. Nature 1992; 357:249-52.
43. Liu GY, Wraith DC. Affinity for class II MHC determines the extent to which soluble peptides tolerize autoreactive T cells in naïve and primed adult mice - implications for autoimmunity. Int Immunol 1995; 7:1255-63.
44. Pender MP, Csurhes PA, Greer JM et al. Surges of increased T cell reactivity to an encephalitogenic region of myelin proteolipid protein occur more often in patients with multiple sclerosis than in healthy subjects. J Immunol 2000; 165:5322-31.
45. Mazza G, Ponsford M, Lowrey P, Campbell MJ, Zajicek J, Wraith DC. Diversity and dynamics of the T-cell response to MBP in DR2+ve individuals. Clin Exp Immunol 2002; 128:538-47.
46. +T cells on tetanus toxin: identification of immunodominant sequence segments. Infect Dis 1997; 175:382-91.
47. Reece JC, Geysen M, Rodda SJ. Mapping the major human T helper epitopes of tetanus toxin. The emerging picture. J Immunol 1993; 151:6175-84.
48. Decary F, L'Abbe D, Tremblay L, Chartrand P. The immune response to the HPA-1a antigen: association with HLA-DRw52a. Transfus Med 1991; 1:55-62.