A novel method of measuring reduction of nitrite-induced methemoglobin applied to fetal and adult blood of humans and sheep

Journal of Applied Physiology

Volumn 103, Issue 4, 2007, Pages 1359-1365

  Power, Gordon G ^a   Bragg, Shannon L ^a   Oshiro, Bryan T ^a   Dejam, Andre ^b   Hunter, Christian J ^b   Blood, Arlin B ^a  

^a LOMA LINDA UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b BRIGHAM AND WOMEN S HOSPITAL   (United States)

Author keywords

Fetus; Methemoglobin reductase; Whole blood

Indexed keywords

CARBON MONOXIDE; DEOXYHEMOGLOBIN; METHEMOGLOBIN; METHEMOGLOBIN REDUCTASE; METHYLENE BLUE; NITRIC OXIDE; NITRITE;

ADULT; ANALYTIC METHOD; ANOXIA; ARTICLE; BIOACCUMULATION; DIFFUSION; ENERGY; ENZYME ACTIVITY; ERYTHROCYTE; FETUS; HEMOLYSIS; HUMAN; HYPOXIA; NEWBORN; NONHUMAN; OXYGEN TENSION; PH; PRIORITY JOURNAL; QUANTITATIVE ANALYSIS; REDUCTION; SHEEP; TEMPERATURE DEPENDENCE; UMBILICAL CORD BLOOD;

ADULT; ANIMALS; CARBON MONOXIDE; CYTOCHROME-B(5) REDUCTASE; DRUG COMBINATIONS; FETAL BLOOD; HUMANS; INDICATORS AND REAGENTS; INFANT, NEWBORN; METHEMOGLOBIN; METHEMOGLOBINEMIA; OXIDATION-REDUCTION; REPRODUCIBILITY OF RESULTS; SHEEP; SODIUM NITRITE;

EID: 35349029711     PISSN: 87507587     EISSN: 15221601     Source Type: Journal    
DOI: 10.1152/japplphysiol.00443.2007     Document Type: Article

References (46)

1. Bartos HR, Desforges JF. Erythrocyte DPNH dependent diaphorase levels in infants. Pediatrics 37: 991-993, 1966.
2. Beutler E, Baluda MC. Methemoglobin reduction. Studies of the interaction between cell populations and of the role of methylene blue. Blood 22: 323-333, 1963.
3. Board PG. NADH-ferricyanide reductase, a convenient approach to the evaluation of NADH-methaemoglobin reductase in human erythrocytes. Clin Chim Acta 109: 233-237, 1981.
4. Borgese N, Pietrini G, Gaetani S. Concentration of NADH-cytochrome b5 reductase in erythrocytes of normal and methemoglobinemic individuals measured with a quantitative radioimmunoblotting assay. J Clin Invest 80: 1296-1302, 1987.
5. Bradberry SM. Occupational methaemoglobinaemia. Mechanisms of production, features, diagnosis and management including the use of methylene blue. Toxicol Rev 22: 13-27, 2003.
6. Brin M, Yonemoto RH. Stimulation of the glucose oxidative pathway in human erythrocytes by methylene blue. J Biol Chem 230: 307-317, 1958.
7. Bunn HF, Forget BG, Ranney HM. Human Hemoglobins. Philadelphia, PA: Saunders, 1977, p. 432.
8. Choury D, Leroux A, Kaplan JC. Membrane-bound cytochrome b5 reductase (methemoglobin reductase) in human erythrocytes. Study in normal and methemoglobinemic subjects. J Clin Invest 67: 149-155, 1981.
9. Dejam A, Hunter CJ, Pelletier MM, Hsu LL, Machado RF, Shiva S, Power GG, Kelm M, Gladwin MT, Schechter AN. Erythrocytes are the major intravascular storage sites of nitrite in human blood. Blood 106: 734-739, 2005.
10. Doyle MP, Pickering RA, DeWeert TM, Hoekstra JW, Pater D. Kinetics and mechanism of the oxidation of human deoxyhemoglobin by nitrites. J Biol Chem 256: 12393-12398, 1981.
11. Duranski MR, Greer JJ, Dejam A, Jaganmohan S, Hogg N, Langston W, Patel RP, Yet SF, Wang X, Kevil CG, Gladwin MT, Lefer DJ. Cytoprotective effects of nitrite during in vivo ischemia-reperfusion of the heart and liver. J Clin Invest 115: 1232-1240, 2005.
12. Fernandez BO, Lorkovic IM, Ford PC. Mechanisms of ferriheme reduction by nitric oxide: nitrite and general base catalysis. Inorg Chem 43: 5393-5402, 2004.
13. Gladwin MT, Raat NJ, Shiva S, Dezfulian C, Hogg N, Kim-Shapiro DB, Patel RP. Nitrite as a vascular endocrine nitric oxide reservoir that contributes to hypoxic signaling, cytoprotection, and vasodilation. Am J Physiol Heart Circ Physiol 291: H2026-H2035, 2006.
14. Gruener N. Ontogenetic development of NADH-dependent methemoglobin reductase in erythrocytes of man and rat. J Toxicol Environ Health 1: 787-791, 1976.
15. Herzog P, Feig SA. Methaemoglobinaemia in the newborn infant. Clin Haematol 7: 75-83, 1978.
16. Hsieh HS, Jaffe ER. Electrophoretic and functional variants of NADH-methemoglobin reductase in hereditary methemoglobinemia. J Clin Invest 50: 196-202, 1971.
17. Huennekens FM, Liu L, Myers HA, Gabrio BW 3rd. Erythrocyte metabolism. Oxidation of glucose. J Biol Chem 227: 253-260, 1957.
18. Hultquist DE, Passon PG. Catalysis of methaemoglobin reduction by erythrocyte cytochrome b5 and cytochrome b5 reductase. Nature 229: 252-254, 1971.
19. Hunter CJ, Dejam A, Blood AB, Shields H, Kim-Shapiro DB, Machado RF, Tarekegn S, Mulla N, Hopper AO, Schechter AN, Power GG, Gladwin MT. Inhaled nebulized nitrite is a hypoxia-sensitive NO-dependent selective pulmonary vasodilator. Nat Med 10: 1122-1127, 2004.
20. Jaffe ER. Methemoglobin pathophysiology. Prog Clin Biol Res 51: 133-151, 1981.
21. Kiese M. Methemoglobinemia. A Comprehensive Treatise. Cleveland, OH: CRC, 1974.
22. Kinoshita A, Nakayama Y, Kitayama T, Tomita M. Simulation study of methemoglobin reduction in erythrocytes. Differential contributions of two pathways to tolerance to oxidative stress. FEBS J 274: 1449-1458, 2007.
23. Kleinbongard P, Dejam A, Lauer T, Rassaf T, Schindler A, Picker O, Scheeren T, Godecke A, Schrader J, Schulz R, Heusch G, Schaub GA, Bryan NS, Feelisch M, Kelm M. Plasma nitrite reflects constitutive nitric oxide synthase activity in mammals. Free Radic Biol Med 35: 790-796, 2003.
24. Klimmek R, Krettek C, Werner HW. Ferrihaemoglobin formation by amyl nitrite and sodium nitrite in different species in vivo and in vitro. Arch Toxicol 62: 152-160, 1988.
25. Kosaka H, Imaizumi K, Imai K, Tyuma I. Stoichiometry of the reaction of oxyhemoglobin with nitrite. Biochim Biophys Acta 581: 184-188, 1979.
26. Lan F, Tang Y, Huang C, Zhu Z. Determination of concentration of cytosolic NADH-cytochrome b5 reductase in erythrocytes from normal Chinese adults, neonates and patients with hereditary methemoglobinemia by double-antibody sandwich ELISA. Acta Haematol 100: 44-48, 1998.
27. Lo SC, Agar NS. NADH-methemoglobin reductase activity in the erythrocytes of newborn and adult mammals. Experientia 42: 1264-1265, 1986.
28. May JM, Qu ZC, Cobb CE. Reduction and uptake of methylene blue by human erythrocytes. Am J Physiol Cell Physiol 286: C1390-C1398, 2004.
29. Miyazono Y, Hirono A, Miyamoto Y, Miwa S. Erythrocyte enzyme activities in cord blood of extremely low-birth-weight infants. Am J Hematol 62: 88-92, 1999.
30. Neugebauer JM. Detergents: an overview. Methods Enzymol 182: 239-253, 1990.
31. Passon PG, Hultquist DE. Soluble cytochrome b5 reductase from human erythrocytes. Biochim Biophys Acta 275: 62-73, 1972.
32. Percy MJ, McFerran NV, Lappin TR. Disorders of oxidised haemoglobin. Blood Rev 19: 61-68, 2005.
33. Pluta RM, Dejam A, Grimes G, Gladwin MT, Oldfield EH. Nitrite infusions to prevent delayed cerebral vasospasm in a primate model of subarachnoid hemorrhage. JAMA 293: 1477-1484, 2005.
34. Reinke NB, O'Brien GM. High activity antioxidant enzymes protect flying-fox haemoglobin against damage: an evolutionary adaptation for flight? J Comp Physiol [B] 176: 729-737, 2006.
35. Rockwood GA, Armstrong KR, Baskin SI. Species comparison of methemoglobin reductase. Exp Biol Med (Maywood) 228: 79-83, 2003.
36. Ross JD. Deficient activity of DPNH-dependent methemoglobin diaphorase in cord blood erythrocytes. Blood 21: 51-62, 1963.
37. Sass MD, Caruso CJ, Axelrod DR. Mechanism of the TPNH-linked reduction of methemoglobin by methylene blue. Clin Chim Acta 24: 77-85, 1969.
38. Sass MD, Caruso CJ, Farhangi M. TPNH-methemoglobin reductase deficiency: a new red-cell enzyme defect. J Lab Clin Med 70: 760-767, 1967.
39. Scott EM, Duncan IW, Ekstrand V. The reduced pyridine nucleotide dehydrogenases of human erythrocytes. J Biol Chem 240: 481-485, 1965.
40. Smith JE, Beutler E. Methemoglobin formation and reduction in man and various animal species. Am J Physiol 210: 347-350, 1966.
41. Stein WD. The Movement of Molecules Across Cell Membranes. New York: Academic, 1967.
42. Tanishima K, Fukuda N, Takeshita M, Takizawa Y, Kitamura T, Yoneyama Y. Automated determination of red cell methaemoglobin reductase activity by a continuous-flow system for screening hereditary methaemoglobinaemia. J Clin Pathol 32: 584-589, 1979.
43. Vetrella M, Astedt B, Barthelmai W, Neuvians D. Activity of NADH- and NADPH-dependent methemoglobin reductases in erythrocytes from fetal to adult age. A parallel assessment. Klin Wochenschr 49: 972-977, 1971.
44. Wennmalm A, Benthin G, Petersson AS. Dependence of the metabolism of nitric oxide (NO) in healthy human whole blood on the oxygenation of its red cell haemoglobin. Br J Pharmacol 106: 507-508, 1992.
45. Young JD, Dyar O, Xiong L, Howell S. Methaemoglobin production in normal adults inhaling low concentrations of nitric oxide. Intensive Care Med 20: 581-584, 1994.
46. Young JD, Sear JW, Valvini EM. Kinetics of methaemoglobin and serum nitrogen oxide production during inhalation of nitric oxide in volunteers. Br J Anaesth 76: 652-656, 1996.