Hypoxia transduction by carotid body chemoreceptors in mice lacking dopamine D2 receptors

Journal of Applied Physiology

Volumn 103, Issue 4, 2007, Pages 1269-1275

  Prieto Lloret, J ^a   Donnelly, D F ^b   Rico, A J ^a   Moratalla, R ^c   Gonzalez C ^a   Rigual, R J ^a,d  

^a CSIC   (Spain)

^b YALE UNIVERSITY SCHOOL OF MEDICINE   (United States)

^c INSTITUTO CAJAL   (Spain)

^d Universidad de Valladolid y Consejo Superior de Investigaciones Científicas   (Spain)

Author keywords

Arterial chemoreceptors; Chemoreception; Hypoxia sensing

Indexed keywords

CATECHOLAMINE; DOPAMINE; DOPAMINE 2 RECEPTOR; POSTSYNAPTIC RECEPTOR; SODIUM CHLORIDE;

ANIMAL TISSUE; ARTICLE; BRAIN STEM; CAROTID BODY; CAROTID BODY CHEMORECEPTOR; CATECHOLAMINE RELEASE; CONTROLLED STUDY; DOPAMINE RELEASE; FEMALE; HYPOXIA; IN VITRO STUDY; LUNG VENTILATION; MOUSE; NERVE ENDING; NEUROTRANSMISSION; NONHUMAN; PRIORITY JOURNAL; RECEPTOR UPREGULATION; SENSORY NERVE; WILD TYPE;

EID: 35349009972     PISSN: 87507587     EISSN: 15221601     Source Type: Journal    
DOI: 10.1152/japplphysiol.00391.2007     Document Type: Article

References (52)

1. Alcayaga J, Varas R, Arroyo J, Iturriaga R, Zapata P. Dopamine modulates carotid nerve responses induced by acetylcholine on the cat petrosal ganglion in vitro. Brain Res 831: 97-103, 1999.
2. 2-adrenoceptor-mediated inhibition in rabbit carotid body. Am J Physiol Cell Physiol 272: C628-C637, 1997.
3. Bairam A, Dauphin C, Rousseau F, Khandjian EW. Dopamine D2 receptor mRNA isoforms expression in the carotid body and petrosal ganglion of developing rabbits. Adv Exp Med Biol 410: 285-289, 1996.
4. Bairam A, Khandjian EW. Expression of dopamine D2 receptor mRNA isoforms in the carotid body of rat, cat and rabbit. Brain Res 760: 287-289, 1997.
5. Bairam A, Frenette J, Dauphin C, Carroll JL, Khandjian EW. Expression of dopamine D1-receptor mRNA in the carotid body of adult rabbits, cats and rats. Neurosci Res 31: 147-154, 1998.
6. Basson H, Bairam A, Cottet-Emard JM, Pequignot JM, Marchal F. Carotid body dopamine content and release by short-term hypoxia: effect of haloperidol and alpha methyl paratyrosine. Arch Physiol Biochem 105: 3-9, 1997.
7. Benishin CG, Krueger BK, Blaustein MP. Phenothiazines and haloperidol block Ca-activated K channels in rat forebrain synaptosomes. Mol Pharmacol 33: 195-201, 1988.
8. 2+ currents by dopamine in glomus cells of the carotid body. Eur J Neurosci 2: 809-812, 1990.
9. + currents of petrosal neurons with projections to the carotid body. J Neurophysiol 88: 2993-3002, 2002.
10. Czyzyk-Krzeska MF, Lawson EE, Millhorn DE. Expression of D2 dopamine receptor mRNA in the arterial chemoreceptor afferent pathway. J Auton Nerv Syst 41: 31-39, 1992.
11. 3H] spiroperidol binding in normal and denervated carotid bodies. Neurosci Lett 21: 51-55, 1981.
12. Donnelly DF, Smith EJ, Dutton RE. Neural response of carotid chemoreceptors following dopamine blockade. J Appl Physiol 50: 172-177, 1981.
13. Donnelly DF, Doyle TP. Developmental changes in hypoxia-induced catecholamine release from rat carotid body, in vitro. J Physiol 475: 267-275, 1994.
14. Donnelly DF. Does catecholamine secretion mediate the hypoxia-induced increase in nerve activity? Biol Signals 4: 304-309, 1995.
15. Donnelly DF. Chemoreceptor nerve excitation may not be proportional to catecholamine secretion. J Appl Physiol 81: 657-664, 1996.
16. Donnelly DF, Rigual R. Single-unit recordings of arterial chemoreceptors from mouse petrosal ganglia in vitro. J Appl Physiol 88: 1489-1495, 2000.
17. Enhorning G, van Schaik S, Lundgren C, Vargas I. Whole-body plethysmography, does it measure tidal volume of small animals? Can J Physiol Pharmacol 76: 945-951, 1998.
18. Fidone S, Gonzalez C, Yoshizaki K. Effects of low oxygen on the release of dopamine from the rabbit carotid body in vitro. J Physiol 333: 93-110, 1982.
19. Gauda EB, Shirahata M, Fitzgerald RS. D2-dopamine receptor mRNA in the carotid body and petrosal ganglia in the developing cat. Adv Exp Med Biol 360: 317-319, 1994.
20. Gauda EB, Bamford O, Gerfen CR. Developmental expression of tyrosine hydroxylase, D2-dopamine receptor and substance P genes in the carotid body of the rat. Neuroscience 75: 969-977, 1996.
21. Gauda EB, Bamford OS, Northington FJ. Lack of induction of substance P gene expression by hypoxia and absence of neurokinin 1-receptor mRNAs in the rat carotid body. J Auton Nerv Syst 74: 100-108, 1998.
22. 2-dopamine receptor genes in rat peripheral arterial chemoreceptors during postnatal development. Brain Res 872: 1-10, 2000.
23. Gauda EB. Gene expression in peripheral arterial chemoreceptors. Microsc Res Tech 59: 153-167, 2002.
24. Goiny M, Lagercrantz H, Srinivasan M, Ungerstedt U, Yamamoto Y. Hypoxia-mediated in vivo release of dopamine in nucleus tractus solitarii of rabbits. J Appl Physiol 70: 2395-2400, 1991.
25. Gonzalez C, Dinger B, Fidone S. Functional significance of chemoreptor cell neurotransmitters. In: The Carotid Body Chemoreceptors, edited by Gonzalez C. Heidelberg, Germany: Springer, 1997, p. 47-64.
26. Gonzalez C, Almaraz L, Obeso A, Rigual R. Carotid body chemoreceptors: from natural stimuli to sensory discharges. Physiol Rev 74: 829-898, 1994.
27. 5 dopamine receptors are critical for LTP, spatial learning, and LTP-induced arc and zif268 expression in the hippocampus. Cereb Cortex (March 29, 2007). doi:10.1093/cercor/bhm026.
28. Hayashida Y, Koyano H, Eyzaguirre C. An intracellular study of chemosensory fibers and endings. J Neurophysiol 44: 1077-1088, 1980.
29. Hedner J, Hedner T, Jonason J, Lundberg D. Evidence for a dopamine interaction with the central respiratory control-system in the rat. Eur J Pharmacol 81: 603-615, 1982.
30. 2+ signaling modulates voltage-sensitive sodium currents in rat nucleus accumbens neurons. J Neurophysiol 93: 1406-1417, 2005.
31. 2-receptor mRNA in the arterial chemoreflex pathway with chronic hypoxia. Brain Res Mol Brain Res 75: 264-270, 2000.
32. 2 receptors. J Appl Physiol 89: 1142-1150, 2000.
33. Huey KA, Szewczak JM, Powell FL. Dopaminergic mechanisms of neural plasticity in respiratory control: transgenic approaches. Respir Physiol Neurobiol 135: 133-144, 2003.
34. Iturriaga R, Alcayaga J, Zapata P. Dissociation of hypoxia-induced chemosensory responses and catecholamine efflux in cat carotid body superfused in vitro. J Physiol 497: 551-564, 1996.
35. Iturriaga R, Alcayaga J. Neurotransmission in the carotid body: transmitters and modulators between glomus cells and petrosal ganglion nerve terminals. Brain Res Brain Res Rev 47: 46-53, 2004.
36. 2 receptor. Respir Physiol Neurobiol 145: 135-142, 2005.
37. i of rat glomus cells. Brain Res 995: 285-296, 2004.
38. Kelly MA, Rubinstein M, Asa SL, Zhang G, Saez C, Bunzow JR, Allen RG, Hnasko R, BenJonathan N, Grandy DK, Low MJ. Pituitary lactotroph hyperplasia and chronic hyperprolactinemia in dopamine D2 receptor-deficient mice. Neuron 19: 103-113, 1997.
39. 2 chemoreception in carotid body. J Appl Physiol 49: 45-51, 1980.
40. Lever JD, Lewis PR, Boyd JD. Observations on the fine structure and histochemistry of the carotid body in the cat and rabbit. J Anat 93: 478-490, 1959.
41. Mir AK, McQueen DS, Pallot DJ, Nahorski SR. Direct biochemical and neuropharmacological identification of dopamine D2-receptors in the rabbit carotid body. Brain Res 291: 273-283, 1984.
42. Niemi M, Ojala K. Cytochemical demonstration of catecholamines in the human carotid body. Nature 203: 539-540, 1964.
43. Nolan WF, Donnelly DF, Smith EJ, Dutton RE. Haloperidol-induced suppression of carotid chemoreception in vitro. J Appl Physiol 59: 814-820, 1985.
44. Pequignot JM, Spielvogel H, Caceres E, Rodriguez A, Sempore B, Pequignot J, Favier R. Influence of gender and endogenous sex steroids on catecholaminergic structures involved in physiological adaptation to hypoxia. Pflügers Arch 433: 580-586, 1997.
45. Prieto-Lloret J, Caceres AI, Obeso A, Rocher A, Rigual R, Agapito MT, Bustamante R, Castaneda J, Perez-Garcia MT, Lopez-Lopez JR, Gonzalez C. Ventilatory responses and carotid body function in adult rats perinatally exposed to hyperoxia. J Physiol 554: 126-144, 2004.
46. 2 stimulation of the cat carotid body. J Physiol 433: 519-531, 1991.
47. 2+ currents. Pflügers Arch 439: 463-470, 2000.
48. Rigual R, Rico AJ, Prieto-Lloret J, De Felipe C, Gonzalez C, Donnelly DF. Chemoreceptor activity is normal in mice lacking the NK1 receptor. Eur J Neurosci 16: 2078-2084, 2002.
49. Usiello A, Baik JH, Rouge-Pont F, Picetti R, Dierich A, LeMeur M, Piazza PV, Borrelli E. Distinct functions of the two isoforms of dopamine D-2 receptors. Nature 408: 199-203, 2000.
50. Wang ZY, Herman JK, O'Halloran KD, Keith IM, Bisgard GE. Pharmacological and immunochemical evidence of the dopamine D3 receptor in the goat carotid body. Adv Exp Med Biol 499: 49-53, 2001.
51. Zapata P. Chemosensory activity in the carotid body nerve: effects of pharmacological agents. In: The Carotid Body Chemoreceptors, edited by Gonzalez C. Heidelberg, Germany: Springer, 1997, p. 119-146.
52. + channel inhibition via protein kinase C. J Physiol 551: 825-842, 2003.