Mechanisms of α2-adrenoceptor-mediated inhibition in rabbit carotid body

American Journal of Physiology - Cell Physiology

Volumn 272, Issue 2 41-2, 1997, Pages

  Almaraz, L ^a   Perez Garcia M T ^a   Gomez Nino A ^a   Gonzalez C ^a  

^a UNIVERSITY OF VALLADOLID   (Spain)

Author keywords

adenosine 3',5' cyclic monophosphate; adrenergic receptors; calcium currents

Indexed keywords

ALPHA 2 ADRENERGIC RECEPTOR; ALPHA ADRENERGIC RECEPTOR; NORADRENALIN;

ANIMAL TISSUE; ARTICLE; CALCIUM CURRENT; CAROTID BODY; NONHUMAN; NORADRENALIN RELEASE; PRIORITY JOURNAL; PROTEIN LOCALIZATION; RABBIT; SYMPATHETIC INNERVATION; ADRENERGIC SYSTEM; ANIMAL; CHEMORECEPTOR; CYTOLOGY; METABOLISM; NERVE CELL INHIBITION; NERVE ENDING; PHYSIOLOGY; TISSUE DISTRIBUTION;

ANIMALIA; ORYCTOLAGUS CUNICULUS;

ANIMALS; CAROTID BODY; CHEMORECEPTORS; NERVE ENDINGS; NEURAL INHIBITION; NOREPINEPHRINE; RABBITS; RECEPTORS, ADRENERGIC, ALPHA; SYMPATHETIC NERVOUS SYSTEM; TISSUE DISTRIBUTION;

EID: 0031068535     PISSN: 03636143     EISSN: None     Source Type: Journal    
DOI: 10.1152/ajpcell.1997.272.2.c628     Document Type: Article

References (39)

1. Almaraz, L., M. T. Pérez-García, and C. Gonzalez. Presence of D1 receptors in the rabbit carotid body. Neurosci. Lett. 132: 259-262, 1991.
2. Almaraz, L., Z. Z. Wang, L. J. Stensaas, and S. J. Fidone. Release of dopamine from carotid sinus nerve fibers innervating type I cells in the cat carotid body. Biol. Signals 2: 16-26, 1993.
3. Bisgard, G. E., R. A. Mitchell, and D. A. Herbert. Effects of dopamine, norepinephrine and 5-hydroxytryptamine on the carotid body of the dog. Respir. Physiol. 37: 61-80, 1979.
4. Bisgard, G. E., M. Warner, J. Pizarro, W. Niu, and G. Mitchell. Noradrenergic inhibition of the goat carotid body. Adv. Exp. Med. Biol. 337: 259-264, 1993.
5. Eyzaguirre, C., and J. Lewin. The effects of sympathetic stimulation on carotid nerve activity. J. Physiol. Lond. 159: 251-267, 1961.
6. Fidone, S., and C. Gonzalez. Catecholamine synthesis in rabbit carotid body in vitro. J. Physiol. Lond. 333: 69-79, 1982.
7. Folgering, H., J. Ponte, and T. Sadig. Adrenergic mechanisms and chemoreception in the carotid body of the cat and rabbit. J. Physiol. Lond. 325: 1-21, 1982.
8. 2 tension. Proc. Natl. Acad. Sci. USA 88: 2927-2930, 1991.
9. Gomez-Niño, A., B. Dinger, C. Gonzalez, and J. Fidone. Differential stimulus coupling to dopamine and norepinephrine stores in rabbit carotid body type I cells. Brain Res. 525: 160-164, 1990.
10. Gonzalez, C., L. Almaraz, A. Obeso, and R. Rigual. Oxygen and acid chemoreception in the carotid body chemoreceptors. Trends Neurosci. 15: 146-153, 1992.
11. Gonzalez, C., L. Almaraz, A. Obeso, and R. Rigual. Carotid body chemoreceptors: from natural stimuli to sensory discharges. Physiol. Rev. 74: 829-898, 1994.
12. González, E., R. Rigual, S. J. Fidone, and C. Gonzalez. Mechanisms for termination of the action of dopamine in carotid body chemoreceptors. J. Auton. Nerv. Syst. 18: 249-259, 1987.
13. Hille, B. Modulation of ion-channel function by G-protein-coupled receptors. Trends Neurosci. 17: 531-536, 1994.
14. Hofman, B. B., and R. J. Lefkowitz. Adrenergic receptor antagonists. In: The Pharmacological Basis of Therapeutics, edited by A. G. Gilman, T. W. Rall, A. S. Nies, and R. Taylor. New York: Pergamon, 1991, p. 221-243.
15. Kou, Y. R., P. Ernsberger, P. A. Cragg, N. S. Cherniack, and N. R. Prabhakar. Role of alpha 2-adrenergic receptors in the carotid body response to isocapnic hypoxia. Respir. Physiol. 83: 353-364, 1991.
16. 2 in type I chemoreceptor cells. Science Wash. DC 241: 580-582, 1988.
17. + current in chemoreceptor cells of rabbit carotid body. J. Physiol. Lond. 460: 15-32, 1993.
18. Lowry, O. H., N. J. Rosebrough, A. L. Farr, and R. J. Randall. Protein measurement with the Folin phenol reagent. J. Biol. Chem. 193: 265-275, 1951.
19. Matsumoto, S., A. Ibi, T. Magao, and T. Nakajima. Effects of carotid body chemoreceptor stimulation by norepinephrine, epinephrine and tyramine on ventilation in the rabbit. Arch. Int. Pharmacodyn. Ther. 252: 152-161, 1981.
20. Matsumoto, S., A. Mokashi, and S. Lahiri. Influence of ganglioglomerular nerve on carotid chemoreceptor activity in the cat. J. Auton. Nerv. Syst. 15: 7-20, 1986.
21. Matsumoto, S., A. Mokashi, and S. Lahiri. Cervical preganglionic sympathetic nerve activity and chemoreflexes in the cat. J. Appl. Physiol. 62: 1713-1720, 1987.
22. Mir, A. K., D. J. Pallot, and S. R. Nahorski. Catecholamines: their receptors and cyclic AMP generating systems in the carotid body. In: The Peripheral Arterial Chemoreceptors, edited by D. J. Pallot. London: Croom Helm, 1984, p. 311-323.
23. Mitchell, J. H., and D. I. McCloskey. Chemoreceptor responses to sympathetic stimulation and changes in blood pressure. Respir. Physiol. 20: 297-302, 1974.
24. O'Regan, R. G. Responses of carotid body chemosensory activity and blood flow to stimulation of sympathetic nerves in the cat. J. Physiol. Lond. 315: 81-98, 1981.
25. Peers, C., and K. J. Buckler. Transduction of chemostimuli by the type I carotid body cell. J. Membr. Biol. 144: 1-9, 1995.
26. Pérez-García, M. T., L. Almaraz, and C. Gonzalez. Effects of different types of stimulation on cyclic AMP content in the rabbit carotid body: functional significance. J. Neurochem. 55: 1287-1293, 1990.
27. Pérez-García, M. T., L. Almaraz, and C. Gonzalez. Cyclic AMP modulates differentially the release of dopamine induced by hypoxia and other stimuli and increases dopamine synthesis in the rabbit carotid body. J. Neurochem. 57: 1992-2000, 1991.
28. Pérez-García, M. T., A. Gomez-Niño, L. Almaraz, and C. Gonzalez. Neurotransmitters and second messenger systems in the carotid body. Adv. Exp. Med. Biol. 337: 279-287, 1993.
29. Pizarro, J., M. M. Warner, M. Ryan, G. S. Mitchell, and G. E. Bisgard. Intracarotid norepinephrine infusions inhibit ventilation in goats. Respir. Physiol. 90: 299-310, 1992.
30. Prabhakar, N. R., and Y. R. Kou. Inhibitory sympathetic action on the carotid body response to sustained hypoxia. Respir. Physiol. 95: 67-79, 1994.
31. Prabhakar, N. R., Y. R. Kou, P. A. Cragg, and N. S. Cherniak. Effect of arterial chemoreceptor stimulation: role of norepinephrine in hypoxic chemotransmission. Adv. Exp. Med. Biol. 337: 301-306, 1993.
32. 2-adrenoceptor subtypes. Annu. Rev. Pharmacol. Toxicol. 32: 243-279, 1993.
33. Sampson, S. R., M. J. Aminoff, R. A. Jaffe, and E. H. Vidruk. A pharmacological analysis of neurally induced inhibition of carotid body chemoreceptor activity in cats. J. Pharmacol. Exp. Ther. 197: 119-125, 1976.
34. Starke, K., M. Göthert, and H. Kilbinger. Modulation of neurotransmitter release by presynaptic autoreceptors. Physiol. Rev. 69: 864-989, 1989.
35. Summers, R. J., and L. R. McMartin. Adrenoceptors and their second messenger systems. J. Neurochem. 60: 10-23, 1993.
36. 2-adrenoceptors. J. Auton. Pharmacol. 1: 171-183, 1981.
37. Verna, A., A. Schamel, and J. M. Péquignot. Noradrenergic glomus cells in the carotid body: an autoradiographic and immunocytochemical study in the rabbit and rat. Adv. Exp. Med. Biol. 337: 93-100, 1993.
38. Wang, W. J., G. F. Cheng, K. Yoshizaki, B. Dinger, and S. Fidone. The role of cyclic AMP in chemoreception in the rabbit carotid body. Brain Res. 540: 96-104, 1991.
39. Wang, Z. Z., L. J. Stensaas, J. De Vente, B. Dinger, and S. Fidone. Immunocytochemical localization of cAMP and cGMP in cells of the rat carotid body following natural and pharmacological stimulation. Histochemistry 96: 523-530, 1991.