Acetazolamide protects against posthypoxic unstable breathing in the C57BL/6J mouse

Journal of Applied Physiology

Volumn 103, Issue 4, 2007, Pages 1263-1268

  Yamauchi, Motoo ^a,b   Dostal, Jesse ^b   Strohl, Kingman P ^a,b  

^a CASE WESTERN RESERVE UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b LOUIS STOKES CLEVELAND VA MEDICAL CENTER   (United States)

Author keywords

Carbonic anhydrase inhibitor; Periodic breathing; Ventilation

Indexed keywords

ACETAZOLAMIDE; CARBON DIOXIDE; CARBONATE DEHYDRATASE INHIBITOR; NITROGEN; OXYGEN;

AMBIENT AIR; ANIMAL EXPERIMENT; APNEA; ARTICLE; BODY PLETHYSMOGRAPHY; BREATHING; CONTROLLED STUDY; HYPEROXIA; HYPOXIA; LUNG MINUTE VOLUME; LUNG VENTILATION; MALE; MOUSE; NONHUMAN; PRIORITY JOURNAL; REOXYGENATION; TIDAL VOLUME;

ACETAZOLAMIDE; ANIMALS; ANOXIA; CARBONIC ANHYDRASE INHIBITORS; DISEASE MODELS, ANIMAL; HYPERCAPNIA; MALE; MICE; MICE, INBRED C57BL; PERIODICITY; PLETHYSMOGRAPHY, WHOLE BODY; PULMONARY VENTILATION; RESPIRATION; RESPIRATION DISORDERS;

EID: 35348981757     PISSN: 87507587     EISSN: 15221601     Source Type: Journal    
DOI: 10.1152/japplphysiol.01287.2006     Document Type: Article

References (33)

1. Ahmed M, Serrette C, Kryger MH, Anthonisen NR. Ventilatory instability in patients with congestive heart failure and nocturnal Cheyne-Stokes breathing. Sleep 17: 527-534, 1994.
2. Burgess KR. Central sleep apnoea and heart failure (Part I). Respirology 2: 243-253, 1997.
3. Cammer WB, Brion LP. Carbonic anhydrase in the nervous system. EXS 90: 475-489, 2000.
4. Cherniack NS, Longobardo GS, Levine OR, Mellins R, Fishman AP. Periodic breathing in dogs. J Appl Physiol 21: 1847-1854, 1966.
5. Cho CH, Ogle CW. Dissociation between the renal and blood acid-base actions of acetazolamide in restraint-stressed rats. Pharmacol Res 22: 619-625, 1990.
6. Dempsey JA, Smith CA, Harms CA, Chow C, Saupe KW. Sleep-induced breathing instability. University of Wisconsin-Madison Sleep and Respiration Research Group. Sleep 19: 236-247, 1996.
7. Dick TE, Coles SK. Ventrolateral pons mediates short-term depression of respiratory frequency after brief hypoxia. Respir Physiol 121: 87-100, 2000.
8. Han F, Subramanian S, Dick TE, Dreshaj IA, Strohl KP. Ventilatory behavior after hypoxia in C57BL/6J and A/J mice. J Appl Physiol 91: 1962-1970, 2001.
9. Han F, Subramanian S, Price ER, Nadeau J, Strohl KP. Periodic breathing in the mouse. J Appl Physiol 92: 1133-1140, 2002.
10. Hanson MA, Nye PC, Torrance RW. The location of carbonic anhydrase in relation to the blood-brain barrier at the medullary chemoreceptors of the cat. J Physiol 320: 113-125, 1981.
11. Hewitt A, Barrie R, Graham M, Bogus K, Leiter JC, Erlichman JS. Ventilatory effects of gap junction blockade in the RTN in awake rats. Am J Physiol Regul Integr Comp Physiol 287: R1407-R1418, 2004.
12. Javaheri S. Acetazolamide improves central sleep apnea in heart failure: a double-blind, prospective study. Am J Respir Crit Care Med 173: 234-237, 2006.
13. Khoo MC, Kronauer RE, Strohl KP, Slutsky AS. Factors inducing periodic breathing in humans: a general model. J Appl Physiol 53: 644-659, 1982.
14. + sensing: peripheral and central chemoreception. Int J Biochem Cell Biol 35: 1413-1435, 2003.
15. Lehtonen J, Shen B, Vihinen M, Casini A, Scozzafava A, Supuran CT, Parkkila AK, Saarnio J, Kivela AJ, Waheed A, Sly WS, Parkkila S. Characterization of CA XIII, a novel member of the carbonic anhydrase isozyme family. J Biol Chem 279: 2719-2727, 2004.
16. Leung RS, Bradley TD. Sleep apnea and cardiovascular disease. Am J Respir Crit Care Med 164: 2147-2165, 2001.
17. Maren TH. Carbonic anhydrase: chemistry, physiology, inhibition. Physiol Rev 47: 595-781, 1967.
18. Parisian K, Wages P, Smith A, Jarosz J, Hewitt A, Leiter JC, Erlichman JS. Ventilatory effects of gap junction blockade in the NTS in awake rats. Respir Physiol Neurobiol 142: 127-143, 2004.
19. Powell FL, Milsom WK, Mitchell GS. Time domains of the hypoxic ventilatory response. Respir Physiol 112: 123-134, 1998.
20. Price ER, Han F, Dick TE, Strohl KP. 7-Nitroindazole and posthypoxic ventilatory behavior in the A/J and C57BL/6J mouse strains. J Appl Physiol 95: 1097-1104, 2003.
21. Schlenker E, Shi Y, Johnson C, Wipf J. Acetazolamide affects breathing differently in ICR and C57 mice. Respir Physiol Neurobiol 152: 119-127, 2006.
22. Sly WS, Hu PY. Human carbonic anhydrases and carbonic anhydrase deficiencies. Annu Rev Biochem 64: 375-401, 1995.
23. Swenson ER. Respiratory and renal roles of carbonic anhydrase in gas exchange and acid-base regulation. EXS 90: 281-341, 2000.
24. Taki K, Oogushi K, Hirahara K, Gai X, Nagashima F, Tozuka K. Preferential acetazolamide-induced vasodilation based on vessel size and organ: confirmation of peripheral vasodilation with use of colored microspheres. Angiology 52: 483-488, 2001.
25. Teppema L, Berkenbosch A, DeGoede J, Olievier C. Carbonic anhydrase and control of breathing: different effects of benzolamide and methazolamide in the anaesthetized cat. J Physiol 488: 767-777, 1995.
26. Teppema LJ, Dahan A. Low-dose acetazolamide reduces the hypoxic ventilatory response in the anesthetized cat. Respir Physiol Neurobiol 140: 43-51, 2004.
27. 2 stimulus interaction within the peripheral chemoreceptors in the anaesthetised cat. J Physiol 537: 221-229, 2001.
28. 2 response curve in the anaesthetized cat. J Physiol 495: 227-237, 1996.
29. 2 response during hypoxia in the anaesthetized cat. Eur Respir J 12: 1271-1277, 1998.
30. Wagenaar M, Vos P, Heijdra Y, Teppema L, Folgering H. Comparison of acetazolamide and medroxyprogesterone as respiratory stimulants in hypercapnic patients with COPD. Chest 123: 1450-1459, 2003.
31. Xu F, Zhang Z, Frazier DT. Microinjection of acetazolamide into the fastigial nucleus augments respiratory output in the rat. J Appl Physiol 91: 2342-2350, 2001.
32. Younes M. The physiologic basis of central apnea and periodic breathing. Curr Pulmonol 10: 265-326, 1989.
33. 2/pH chemosensory signaling in co-cultures of rat carotid body receptors and petrosal neurons: role of ATP and ACh. J Neurophysiol 92: 3433-3445, 2004.