Mandibular bone repair by implantation of rhBMP-2 in a slow release carrier of polylactic acid-An experimental study in rats

Biomaterials

Volumn 29, Issue 1, 2008, Pages 103-110

  Schliephake, Henning ^a   Weich, Herbert A ^b   Dullin, Christian ^a   Gruber, Rudolf ^a   Frahse, Sarah ^a  

^a UNIVERSITY OF GÖTTINGEN   (Germany)

^b HELMHOLTZ CENTRE FOR INFECTION RESEARCH   (Germany)

Author keywords

Bone morphogenetic proteins (BMP); Bone tissue engineering; Drug delivery; Polylactic acid; Recombinant protein

Indexed keywords

ANIMALS; BONE; COMPUTER SIMULATION; COMPUTERIZED TOMOGRAPHY; DRUG DELIVERY; LACTIC ACID; PROTEINS; TISSUE ENGINEERING;

HUMAN RECOMBINANT BONE MORPHOGENIC PROTEIN 2 (RHBMP-2); MANDIBULAR BONE REPAIR; OSTEOGENIC SIGNALS; POLYLACTIC ACID; POLYLACTIC ACID (PLA);

BIOMATERIALS;

BONE MORPHOGENETIC PROTEIN 2; POLYLACTIC ACID; RECOMBINANT PROTEIN;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BONE REMODELING; BONE TISSUE; COMPUTER ASSISTED TOMOGRAPHY; CONTROLLED STUDY; FRACTURE NONUNION; GENE INSERTION; IMPLANT; MALE; MANDIBLE; MORPHOMETRICS; NONHUMAN; OSSIFICATION; OSTEOSCLEROSIS; PRIORITY JOURNAL; RAT; SLOW DRUG RELEASE; TREATMENT OUTCOME;

ANIMALS; BONE AND BONES; BONE MORPHOGENETIC PROTEINS; DRUG CARRIERS; HUMANS; IMPLANTS, EXPERIMENTAL; LACTIC ACID; MALE; MANDIBLE; POLYMERS; RATS; RATS, WISTAR; RECOMBINANT PROTEINS; TOMOGRAPHY SCANNERS, X-RAY COMPUTED; TRANSFORMING GROWTH FACTOR BETA;

ANIMALIA; RATTUS; RATTUS NORVEGICUS;

EID: 35348980299     PISSN: 01429612     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.biomaterials.2007.09.019     Document Type: Article

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