p400 function is required for the adenovirus E1A-mediated suppression of EGFR and tumour cell killing

Oncogene

Volumn 26, Issue 48, 2007, Pages 6863-6874

  Flinterman, M B ^a   Mymryk, J S ^b   Klanrit, P ^a   Yousef, A F ^b   Lowe, S W ^c   Caldas, C ^d   Gaken J ^a   Farzaneh, F ^a   Tavassoli, M ^a,e  

^a KING'S COLLEGE LONDON   (United Kingdom)

^b UNIVERSITY OF WESTERN ONTARIO   (Canada)

^c Howard Hughes Medical Institute Cold Spring Harbor Laboratory Cold Spring Harbor   (United States)

^d UNIVERSITY OF CAMBRIDGE   (United Kingdom)

^e ST THOMAS HOSPITAL   (United Kingdom)

Author keywords

Apoptosis; E1A; EGFR; Head and neck cancer; p400

Indexed keywords

E1A ASSOCIATED P300 PROTEIN; EPIDERMAL GROWTH FACTOR RECEPTOR; HISTONE ACETYLTRANSFERASE PCAF; ISOPROTEIN; PROTEIN; PROTEIN P400; PROTEIN PRB; SHORT HAIRPIN RNA; UNCLASSIFIED DRUG;

APOPTOSIS; ARTICLE; CANCER CELL; CELL KILLING; CONTROLLED STUDY; EMBRYO; HEAD AND NECK CANCER; HUMAN; HUMAN ADENOVIRUS; HUMAN ADENOVIRUS 12; HUMAN ADENOVIRUS 2; HUMAN ADENOVIRUS 3; HUMAN ADENOVIRUS 4; HUMAN ADENOVIRUS 40; HUMAN ADENOVIRUS 9; HUMAN CELL; MUTANT; PRIORITY JOURNAL; PROTEIN BINDING; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN PROTEIN INTERACTION; RECEPTOR DOWN REGULATION; TUMOR CELL;

ADENOVIRUS E1A PROTEINS; ADENOVIRUSES, HUMAN; APOPTOSIS; BLOTTING, WESTERN; CARCINOMA, SQUAMOUS CELL; CELL PROLIFERATION; COLONIC NEOPLASMS; DNA HELICASES; DNA-BINDING PROTEINS; E1A-ASSOCIATED P300 PROTEIN; GENE EXPRESSION REGULATION; HEAD AND NECK NEOPLASMS; HUMANS; LUNG NEOPLASMS; PROTEIN ISOFORMS; RECEPTOR, EPIDERMAL GROWTH FACTOR; RETINOBLASTOMA PROTEIN; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; RNA, MESSENGER; TRANS-ACTIVATION (GENETICS); TRANSFECTION; TUMOR CELLS, CULTURED; TUMOR SUPPRESSOR PROTEIN P53;

ADENOVIRIDAE; HUMAN ADENOVIRUS;

EID: 35348962620     PISSN: 09509232     EISSN: 14765594     Source Type: Journal    
DOI: 10.1038/sj.onc.1210497     Document Type: Article

References (38)

1. Avvakumov N, Kajon AE, Hoeben RC, Mymryk JS. (2004). Comprehensive sequence analysis of the E1A proteins of human and simian adenoviruses. Virology 329: 477-492.
2. Avvakumov N, Wheeler R, D'Halluin JC, Mymryk JS. (2002). Comparative sequence analysis of the largest E1A proteins of human and simian adenoviruses. J Virol 76: 7968-7975.
3. Barbeau D, Charbonneau R, Whalen SG, Bayley ST, Branton PE. (1994). Functional interactions within adenovirus E1A protein complexes. Oncogene 9: 359-373.
4. Bergman LM, Blaydes JP. (2006). C-terminal binding proteins: emerging roles in cell survival and tumorigenesis. Apoptosis 11: 879-888.
5. Chan HM, Narita M, Lowe SW, Livingston DM. (2005). The p400 E1A-associated protein is a novel component of the p53 -> p21 senescence pathway. Genes Dev 19: 196-201.
6. Chiou SK, White E. (1997). p300 binding by E1A cosegregates with p53 induction but is dispensable for apoptosis. J Virol 71: 3515-3525.
7. Cuff JA, Barton GJ. (2000). Application of multiple sequence alignment profiles to improve protein secondary structure prediction. Proteins 40: 502-511.
8. Debbas M, White E. (1993). Wild-type p53 mediates apoptosis by E1A, which is inhibited by E1B. Genes Dev 7: 546-554.
9. Egan C, Jelsma TN, Howe JA, Bayley ST, Ferguson B, Branton PE. (1988). Mapping of cellular protein-binding sites on the products of early-region 1A of human adenovirus type 5. Mol Cell Biol 8: 3955-3959.
10. Flinterman M, Gäken J, Farzaneh F, Tavassoli M. (2003). E1A-mediated suppression of EGFR expression and induction of apoptosis in head and neck squamous carcinoma cell lines. Oncogene 22: 1965-1977.
11. Flinterman M, Guelen L, Ezzati-Nik S, Killick R, Melino G, Tominaga K et al. (2005). E1A activates transcription of p73 and Noxa to induce apoptosis. J Biol Chem 280: 5945-5959.
12. Frank SR, Parisi T, Taubert S, Fernandez P, Fuchs M, Chan HM et al. (2003). MYC recruits the TIP60 histone acetyltransferase complex to chromatin. EMBO Rep 4: 575-580.
13. Frisch SM, Mymryk JS. (2002). Adenovirus-5 E1A: paradox and paradigm. Nat Rev Mol Cell Biol 3: 441-452.
14. Fuchs M, Gerber J, Drapkin R, Sif S, Ikura T, Ogryzko V et al. (2001). The p400 complex is an essential E1A transformation target. Cell 106: 297-307.
15. Graham FL, Prevec L. (1991). Manipulation of adenovirus vectors. In: Murray E (ed.). Methods in Molecular Biology, vol. 7. Humana Press: Cliffton, NJ, pp 109-128.
16. Grandis JR, Sok JC. (2004). Signaling through the epidermal growth factor receptor during the development of malignancy. Pharmacol Ther 102: 37-46.
17. Grossman SR, Deato ME, Brignone C, Chan HM, Kung AL, Tagami H et al. (2003). Polyubiquitination of p53 by a ubiquitin ligase activity of p300. Science 300: 342-344.
18. Iyer NG, Chin SF, Ozdag H, Daigo Y, Hu DE, Cariati M et al. (2004). p300 regulates p53-dependent apoptosis after DNA damage in colorectal cancer cells by modulation of PUMA/p21 levels. Proc Natl Acad Sci USA 101: 7386-7391.
19. Jones N, Shenk T. (1979). Isolation of adenovirus type 5 host range deletion mutants defective for transformation of rat embryo cells. Cell 17: 683-689.
20. Kalyankrishna S, Grandis JR. (2006). Epidermal growth factor receptor biology in head and neck cancer. J Clin Oncol 24: 2666-2672.
21. Lowe SW, Ruley HE. (1993). Stabilization of the p53 tumor suppressor is induced by adenovirus 5 E1A and accompanies apoptosis. Genes Dev 7: 535-545.
22. Moran E, Grodzicker T, Roberts RJ, Mathews MB, Zerler B. (1986). Lytic and transforming functions of individual products of the adenovirus E1A gene. J Virol 57: 765-775.
23. Mymryk JS. (1998). Database of mutations within the adenovirus 5 E1A oncogene. Nucleic Acids Res 26: 292-294.
24. Mymryk JS, Shire K, Bayley ST. (1994). Induction of apoptosis by adenovirus type 5 E1A in rat cells requires a proliferation block. Oncogene 9: 1187-1193.
25. Najafi SM, Li Z, Makino K, Shao R, Hung MC. (2003). The adenoviral E1A induces p21WAF1/CIP1 expression in cancer cells. Biochem Biophys Res Commun 305: 1099-1104.
26. Paterson IC, Patel V, Sandy JR, Prime SS, Yeudall WA. (1995). Effects of transforming growth factor beta-1 on growth-regulatory genes in tumour-derived human oral keratinocytes. Br J Cancer 72: 922-927.
27. Prenzel N, Fischer OM, Streit S, Hart S, Ullrich A. (2001). The epidermal growth factor receptor family as a central element for cellular signal transduction and diversification. Endocr Relat Cancer 8: 11-31.
28. Querido E, Teodoro JG, Branton PE. (1997). Accumulation of p53 induced by the adenovirus E1A protein requires regions involved in the stimulation of DNA synthesis. J Virol 71: 3526-3533.
29. Samuelson AV, Lowe SW. (1997). Selective induction of p53 and chemosensitivity in RB-deficient cells by E1A mutants unable to bind the RB-related proteins. Proc Natl Acad Sci USA 94: 12094-12099.
30. Samuelson AV, Narita M, Chan HM, Jin J, de Stanchina E, McCurrach ME et al. (2005). p400 is required for E1A to promote apoptosis. J Biol Chem 280: 21915-21923.
31. Sartor M, Steingrimsdottir H, Elamin F, Gäken J, Warnakulasuriya S, Partridge M et al. (1999). Role of p16/MTS1, cyclin D1 and RB in primary oral cancer and oral cancer cell lines. Br J Cancer 80: 79-86.
32. Shepherd SE, Howe JA, Mymryk JS, Bayley ST. (1993). Induction of the cell cycle in baby rat kidney cells by adenovirus type 5 E1A in the absence of E1B and a possible influence of p53. J Virol 67: 2944-2949.
33. Taubert S, Gorrini C, Frank SR, Parisi T, Fuchs M, Chan HM et al. (2004). E2F-dependent histone acetylation and recruitment of the Tip60 acetyltransferase complex to chromatin in late G1. Mol Cell Biol 24: 4546-4556.
34. Tyteca S, Vandromme M, Legube G, Chevillard-Briet M, Trouche D. (2006). Tip60 and p400 are both required for UV-induced apoptosis but play antagonistic roles in cell cycle progression. EMBO J 25: 1680-1689.
35. Vallian S, Chin KV, Chang KS. (1998). The promyelocytic leukemia protein interacts with Sp1 and inhibits its transactivation of the epidermal growth factor receptor promoter. Mol Cell Biol 18: 7147-7156.
36. Wang HG, Rikitake Y, Carter MC, Yaciuk P, Abraham SE, Zerler B et al. (1993). Identification of specific adenovirus E1A N-terminal residues critical to the binding of cellular proteins and to the control of cell growth. J Virol 67: 476-488.
37. Yan DH, Chang LS, Hung MC. (1991). Repressed expression of the HER-2/c-erbB-2 proto-oncogene by the adenovirus E1a gene products. Oncogene 6: 343-345.
38. Yu D, Hung MC. (1998). The erbB2 gene as a cancer therapeutic target and the tumor- and metastasis-suppressing function of E1A. Cancer Metastasis Rev 17: 195-202.