-
1
-
-
35348966860
-
Takeuchi K. Healing impairment action of bisphosphonates on acetic acid-induced gastric ulcer in rats
-
in press
-
Amagase, K., Nishikawa, K., Aihara, E. et al. (2006) Takeuchi K. Healing impairment action of bisphosphonates on acetic acid-induced gastric ulcer in rats. Dig Dis Sci, in press.
-
(2006)
Dig Dis Sci
-
-
Amagase, K.1
Nishikawa, K.2
Aihara, E.3
-
2
-
-
0028895213
-
Rebamipide, novel prostaglandin- inducer accelerates healing and reduces relapse of acetic acid-induced rat gastric ulcer. Comparison with cimetidine
-
Arakawa, T., Watanabe, T., Fukuda, T. et al. (1995) Rebamipide, novel prostaglandin- inducer accelerates healing and reduces relapse of acetic acid-induced rat gastric ulcer. Comparison with cimetidine. Dig Dis Sci, 40, 2469-2472.
-
(1995)
Dig Dis Sci
, vol.40
, pp. 2469-2472
-
-
Arakawa, T.1
Watanabe, T.2
Fukuda, T.3
-
3
-
-
0033806009
-
Gastric damage in the rat with nitrogen-containing bisphosphonates depends on pH
-
Blank, M. A., Gibson, G. W., Myers, W. R. et al. (2004) Gastric damage in the rat with nitrogen-containing bisphosphonates depends on pH. Aliment Pharmacol Ther, 14, 1215-1223.
-
(2004)
Aliment Pharmacol Ther
, vol.14
, pp. 1215-1223
-
-
Blank, M.A.1
Gibson, G.W.2
Myers, W.R.3
-
4
-
-
0034838352
-
Effect of local application of growth factors on gastric ulcer healing and mucosal expression of cyclooxygenase-1 and-2
-
Brozozowski, T., Konturek, P. C., Konturek, S. J. et al. (2001) Effect of local application of growth factors on gastric ulcer healing and mucosal expression of cyclooxygenase-1 and-2. Digestion, 64, 15-29.
-
(2001)
Digestion
, vol.64
, pp. 15-29
-
-
Brozozowski, T.1
Konturek, P.C.2
Konturek, S.J.3
-
5
-
-
0031589675
-
Alendronate induces gastric injury and delays ulcer healing in rodents
-
Elliott, S. N., McKnight, W., Davies et al. (1998) Alendronate induces gastric injury and delays ulcer healing in rodents. Life Sci, 62, 77-91.
-
(1998)
Life Sci
, vol.62
, pp. 77-91
-
-
Elliott, S.N.1
McKnight, W.2
Davies3
-
6
-
-
0034789690
-
Effect of local injection with basic fibroblast growth factor (bFGF) and neutralizing antibody to bFGF on gastric ulcer healing, gastric secretion, angiogenesis and gastric blood flow
-
Ernst, H., Konturek, P. C., Hahn, E. G. et al. (2001) Effect of local injection with basic fibroblast growth factor (bFGF) and neutralizing antibody to bFGF on gastric ulcer healing, gastric secretion, angiogenesis and gastric blood flow. J Physiol Pharmacol, 52, 377-390.
-
(2001)
J Physiol Pharmacol
, vol.52
, pp. 377-390
-
-
Ernst, H.1
Konturek, P.C.2
Hahn, E.G.3
-
7
-
-
0022643443
-
Absorption of oral diphosphonate in normal subjects
-
Fogelman, I., Smith, L., Mazes, R. et al (1986) Absorption of oral diphosphonate in normal subjects. Clin Endocrin, 24, 57-62.
-
(1986)
Clin Endocrin
, vol.24
, pp. 57-62
-
-
Fogelman, I.1
Smith, L.2
Mazes, R.3
-
8
-
-
0000192287
-
Structure-activity relationship and therapeutic implications
-
Geddes, A. D., D'Souza, S. M., Ebetino, F. H. et al. (1994) Structure-activity relationship and therapeutic implications. J Bone Miner Res, 8, 265-365.
-
(1994)
J Bone Miner Res
, vol.8
, pp. 265-365
-
-
Geddes, A.D.1
D'Souza, S.M.2
Ebetino, F.H.3
-
9
-
-
0036338869
-
What the gastroenterologist should know about the gastrointestinal safety profiles of bisphosphonates
-
Graham, D. Y. (2002) What the gastroenterologist should know about the gastrointestinal safety profiles of bisphosphonates. Dig Dis Sci, 47, 1665-1678.
-
(2002)
Dig Dis Sci
, vol.47
, pp. 1665-1678
-
-
Graham, D.Y.1
-
10
-
-
0036382867
-
Antiangiogenic effect of a highly selective cyclooxygenase-2 inhibitor on gastric ulcer healing in rats
-
Guo, J. S., Cho, C. H., Liu, E. S. et al. (2002) Antiangiogenic effect of a highly selective cyclooxygenase-2 inhibitor on gastric ulcer healing in rats. Toxicol Appl Pharmacol, 183, 41-45.
-
(2002)
Toxicol Appl Pharmacol
, vol.183
, pp. 41-45
-
-
Guo, J.S.1
Cho, C.H.2
Liu, E.S.3
-
11
-
-
0031026997
-
Role of rebamipide on induction of heat-shock proteins and protection against reactive oxygen metabolite-mediated cell damage in cultured gastric mucosal cells
-
Hahm, K. B., Park, I. S., Kim, Y. S. et al (1997) Role of rebamipide on induction of heat-shock proteins and protection against reactive oxygen metabolite-mediated cell damage in cultured gastric mucosal cells. Free Radical Biol Med, 22, 711-716.
-
(1997)
Free Radical Biol Med
, vol.22
, pp. 711-716
-
-
Hahm, K.B.1
Park, I.S.2
Kim, Y.S.3
-
12
-
-
25644458376
-
Rebamipide reduces indomethacin- induced gastric injury in mice via down-regulation of ICAM-1 expression
-
Hiratsuka, T., Futagami, S., Shindo, T. et al. (2005) Rebamipide reduces indomethacin- induced gastric injury in mice via down-regulation of ICAM-1 expression. Dig Dis Sci, 50 (Suppl), S84-S89.
-
(2005)
Dig Dis Sci
, vol.50
, Issue.SUPPL.
-
-
Hiratsuka, T.1
Futagami, S.2
Shindo, T.3
-
13
-
-
0026619188
-
Effect of rebamipide on mucus secretion by endogenous prostaglandin-independent mechanism in rat gastric mucosa
-
Ishihara, K., Komuro, Y., Nishiyama, N. et al, (1992) Effect of rebamipide on mucus secretion by endogenous prostaglandin-independent mechanism in rat gastric mucosa. Arzneimittel-forschung, 42, 1462-1466.
-
(1992)
Arzneimittel-forschung
, vol.42
, pp. 1462-1466
-
-
Ishihara, K.1
Komuro, Y.2
Nishiyama, N.3
-
14
-
-
2442684025
-
Mucosal irritative and healing impairment action of risedronate in rat stomachs: Comparison with alendronate
-
Kanatsu, K., Aihara, E., Okayama, M. et al. (2004) Mucosal irritative and healing impairment action of risedronate in rat stomachs: Comparison with alendronate. J Gastroent Hapetology, 19, 512-520.
-
(2004)
J Gastroent Hapetology
, vol.19
, pp. 512-520
-
-
Kanatsu, K.1
Aihara, E.2
Okayama, M.3
-
15
-
-
0034070950
-
Inhibition of lipid peroxidation, NF-kappaB activation and IL-8 production by rebamipide in Helicobacter pylori-stimulated gastric epithelial cells
-
Kim, H., Seo, J. Y., Kim, K. H. (2000) Inhibition of lipid peroxidation, NF-kappaB activation and IL-8 production by rebamipide in Helicobacter pylori-stimulated gastric epithelial cells. Dig Dis Sci, 45, 621-628.
-
(2000)
Dig Dis Sci
, vol.45
, pp. 621-628
-
-
Kim, H.1
Seo, J.Y.2
Kim, K.H.3
-
16
-
-
0027217058
-
Stimulation of prostaglandin biosynthesis mediates gastroprotective effect of rebamipide in rats
-
Kleine, A., Kluge, S., Peskar, B. M. (1993) Stimulation of prostaglandin biosynthesis mediates gastroprotective effect of rebamipide in rats. Dig Dis Sci, 38, 1441-1449.
-
(1993)
Dig Dis Sci
, vol.38
, pp. 1441-1449
-
-
Kleine, A.1
Kluge, S.2
Peskar, B.M.3
-
17
-
-
0014949207
-
Cleavage of structural proteins during assembly of the head of bacteriophage T4
-
Laemmli, U. K. (1970) Cleavage of structural proteins during assembly of the head of bacteriophage T4. Nature, 227, 680-685.
-
(1970)
Nature
, vol.227
, pp. 680-685
-
-
Laemmli, U.K.1
-
18
-
-
0033794049
-
Effect of bisphosphonates on surface hydrophobicity and phosphatidylcholine concentration of rodent gastric mucosa
-
Lichtenberger, L. M., Romero, J. J., Gibson, G. W. et al. (2000) Effect of bisphosphonates on surface hydrophobicity and phosphatidylcholine concentration of rodent gastric mucosa. Dig Dis Sci, 45, 1792-1801.
-
(2000)
Dig Dis Sci
, vol.45
, pp. 1792-1801
-
-
Lichtenberger, L.M.1
Romero, J.J.2
Gibson, G.W.3
-
19
-
-
0026077161
-
Physiological disposition of alendronate, a potent anti-osteolytic bisphosphonate, in laboratory animals
-
Lin, J. H., Duggan, D. E., Chen, I. et al. (1991) Physiological disposition of alendronate, a potent anti-osteolytic bisphosphonate, in laboratory animals. Drug Metab Dispos, 19, 297-300.
-
(1991)
Drug Metab Dispos
, vol.19
, pp. 297-300
-
-
Lin, J.H.1
Duggan, D.E.2
Chen, I.3
-
20
-
-
0031977199
-
Nitrogen-containing bisphosphonates inhibit the mevalonate pathway and prevent post-translational prenylation of GTP-binding protein, including rats
-
Luckman, S. P., Hughes, D. E., Coxon, E. P. et al. (1998) Nitrogen-containing bisphosphonates inhibit the mevalonate pathway and prevent post-translational prenylation of GTP-binding protein, including rats. J Bone Miner Res, 13, 581-589.
-
(1998)
J Bone Miner Res
, vol.13
, pp. 581-589
-
-
Luckman, S.P.1
Hughes, D.E.2
Coxon, E.P.3
-
21
-
-
0033694952
-
A randomized controlled trial to assess alendronate-associated injury of the upper gastrointestinal tract
-
Marshall, J. K., Rainsford, K. D., James, C. et al. (2000) A randomized controlled trial to assess alendronate-associated injury of the upper gastrointestinal tract. Aliment Pharmacol Ther, 4, 1451-1457.
-
(2000)
Aliment Pharmacol Ther
, vol.4
, pp. 1451-1457
-
-
Marshall, J.K.1
Rainsford, K.D.2
James, C.3
-
22
-
-
0026656426
-
Role of capsaicin-sensitive afferent neurons in mucosal blood flow response of rat stomach induced by mild irritants
-
Matsumoto, J., Takeuchi, K., Ueshima, K. et al. (1992) Role of capsaicin-sensitive afferent neurons in mucosal blood flow response of rat stomach induced by mild irritants. Dig Dis Sci, 37, 1336-1344.
-
(1992)
Dig Dis Sci
, vol.37
, pp. 1336-1344
-
-
Matsumoto, J.1
Takeuchi, K.2
Ueshima, K.3
-
23
-
-
18544391493
-
Cyclooxygenase-2- regulated vascular endothelial growth factor release in gastric fibroblasts
-
Miura, S., Tatsuguchi, A., Wada, K. et al. (2004) Cyclooxygenase-2- regulated vascular endothelial growth factor release in gastric fibroblasts. Am J Physiol, 287, G444-G451.
-
(2004)
Am J Physiol
, vol.287
-
-
Miura, S.1
Tatsuguchi, A.2
Wada, K.3
-
24
-
-
0031715660
-
Rebamipide prevents indomethacin-induced gastric mucosal lesion formation by inhibiting activation of neutrophils in rats
-
Murakami, K., Okajima, K., Harada, N. et al. (1998) Rebamipide prevents indomethacin-induced gastric mucosal lesion formation by inhibiting activation of neutrophils in rats. Dig Dis Sc, 43, 139S-142S.
-
(1998)
Dig Dis Sc
, vol.43
-
-
Murakami, K.1
Okajima, K.2
Harada, N.3
-
25
-
-
0015362625
-
Chronicity of acetic acid ulcer in the rat stomach
-
Okabe, S., Pfeiffer, C. J. (1972) Chronicity of acetic acid ulcer in the rat stomach. Am J Dig Dis, 17, 619-629.
-
(1972)
Am J Dig Dis
, vol.17
, pp. 619-629
-
-
Okabe, S.1
Pfeiffer, C.J.2
-
26
-
-
0032942599
-
Bisphosphonates: Pharmacology, mechanisms of action and clinical uses
-
Russell, R. G., Croucher, P. I., Roger, M. J. (1999) Bisphosphonates: Pharmacology, mechanisms of action and clinical uses. Osteoporosis Int, 9, S66-S80.
-
(1999)
Osteoporosis Int
, vol.9
-
-
Russell, R.G.1
Croucher, P.I.2
Roger, M.J.3
-
27
-
-
25644432760
-
Rebamipide reduces recurrence of experimental gastric ulcers: Role of free radicals and neutrophils
-
Sakurai, K., Osaka, T., Yamasaki, K. (2005) Rebamipide reduces recurrence of experimental gastric ulcers: role of free radicals and neutrophils. Dig Dis Sci, 50 (Suppl), S90-S96.
-
(2005)
Dig Dis Sci
, vol.50
, Issue.SUPPL.
-
-
Sakurai, K.1
Osaka, T.2
Yamasaki, K.3
-
28
-
-
0032425648
-
Relationship between vascular endothelial growth factor and angiogenesis in spontaneous and indomethacin-delayed healing of acetic acid-induced gastric ulcers in rats
-
Suzuki, N., Takahashi, S., Okabe, S. (1998) Relationship between vascular endothelial growth factor and angiogenesis in spontaneous and indomethacin-delayed healing of acetic acid-induced gastric ulcers in rats. J Physiol Pharmacol, 49, 515-527.
-
(1998)
J Physiol Pharmacol
, vol.49
, pp. 515-527
-
-
Suzuki, N.1
Takahashi, S.2
Okabe, S.3
-
29
-
-
25644437787
-
Cellular and molecular mechanisms of gastrointestinal ulcer healing
-
Tarnawski, A. (2005) Cellular and molecular mechanisms of gastrointestinal ulcer healing. Dig Dis Sci, 50, S24-S33.
-
(2005)
Dig Dis Sci
, vol.50
-
-
Tarnawski, A.1
-
30
-
-
0031667425
-
Rebamipide treatment activates epidermal growth factor and its receptor expression in normal and ulcerated gastric mucosa in rat: One mechanism for its ulcer healing action?
-
Tarnawski, A., Arakawa, T., Kobayashi, K. (1998) Rebamipide treatment activates epidermal growth factor and its receptor expression in normal and ulcerated gastric mucosa in rat: One mechanism for its ulcer healing action? Dig Dis Sci, 43, 90S-98S.
-
(1998)
Dig Dis Sci
, vol.43
-
-
Tarnawski, A.1
Arakawa, T.2
Kobayashi, K.3
-
31
-
-
0036133719
-
Effect of rebamipide on cell death induced by combined treatment of mild heat shock and quercetin in RGM-1 cells: Role for HSP70 induction
-
Tsukimi, Y., Fujishita, K., Okabe, S. (2002) Effect of rebamipide on cell death induced by combined treatment of mild heat shock and quercetin in RGM-1 cells: Role for HSP70 induction. Pharmacology, 64, 28-35.
-
(2002)
Pharmacology
, vol.64
, pp. 28-35
-
-
Tsukimi, Y.1
Fujishita, K.2
Okabe, S.3
-
32
-
-
0031710628
-
Rebamipide prevented delay of wound repair induced by hydrogen peroxide and suppressed apoptosis of gastric epithelial cells in vitro
-
Watanabe, S., Wang, X. E., Hirose, M. et al. (1998) Rebamipide prevented delay of wound repair induced by hydrogen peroxide and suppressed apoptosis of gastric epithelial cells in vitro. Dig Dis Sci, 43 (Suppl), 107S-112S.
-
(1998)
Dig Dis Sci
, vol.43
, Issue.SUPPL.
-
-
Watanabe, S.1
Wang, X.E.2
Hirose, M.3
-
33
-
-
0024519061
-
Effect of OPC-12795, a novel antiulcer agent, on chronic and acute experimental gastric ulcer, and gastric secretion
-
Yamasaki, K., Ishiyama, H., Imaizumi, T. et al. (1989) Effect of OPC-12795, a novel antiulcer agent, on chronic and acute experimental gastric ulcer, and gastric secretion. Jpn J Pharmacol, 49, 441-448.
-
(1989)
Jpn J Pharmacol
, vol.49
, pp. 441-448
-
-
Yamasaki, K.1
Ishiyama, H.2
Imaizumi, T.3
-
34
-
-
0023629705
-
Gastric mucosal protection by OPC-12759, a novel antiulcer compound in the rat
-
Yamasaki, K., Kanbe, T.,Chijiwa, T. et al. (1987) Gastric mucosal protection by OPC-12759, a novel antiulcer compound in the rat. Eur J Pharmacol, 142, 23-29.
-
(1987)
Eur J Pharmacol
, vol.142
, pp. 23-29
-
-
Yamasaki, K.1
Kanbe, T.2
Chijiwa, T.3
-
35
-
-
35349031706
-
Effect of rebamipide on gastric transmucosal potential difference and gastric acid back diffusion in the rat
-
Yamasaki, K., Kane, T. (1990) Effect of rebamipide on gastric transmucosal potential difference and gastric acid back diffusion in the rat. Jpn Pharmacol Ther, 18, 147-152.
-
(1990)
Jpn Pharmacol Ther
, vol.18
, pp. 147-152
-
-
Yamasaki, K.1
Kane, T.2
-
36
-
-
0027460826
-
Free radical scavenging activity of the novel anti-ulcer agent rebamipide studied by electron spin resonance
-
Yoshikawa, T., Naito, Y., Tanigawa, T. et al. (1993) Free radical scavenging activity of the novel anti-ulcer agent rebamipide studied by electron spin resonance. Arzneimittelforschung, 43, 363-366.
-
(1993)
Arzneimittelforschung
, vol.43
, pp. 363-366
-
-
Yoshikawa, T.1
Naito, Y.2
Tanigawa, T.3
|