Cord blood cytokine profile detection in neonates with T1D parents - Monitoring of cellular auto-reactivity using protein microarray

Scandinavian Journal of Immunology

Volumn 66, Issue 5, 2007, Pages 563-571

  Bohmova, K ^b   Hladikova, Z ^b,c   Cerny, M ^b   Flajsmanova, K ^b   Vrabelova, Z ^b   Skramlikova, T ^b   Spalova, I ^b   Cerna, M ^d   Chudoba, D ^b   Pithova, P ^b   Stadlerova, G ^b   Bartaskova, D ^b   Faresjo, M ^e   Stechova, K ^a,b  

^a UNIVERSITY HOSPITAL MOTOL   (Czech Republic)

^b CHARLES UNIVERSITY   (Czech Republic)

^c CZECH UNIVERSITY OF LIFE SCIENCES PRAGUE   (Czech Republic)

^d INSTITUTE FOR THE CARE OF MOTHER AND CHILD   (Czech Republic)

^e LINKÖPING UNIVERSITY   (Sweden)

Author keywords

[No Author keywords available]

Indexed keywords

AUTOANTIGEN; CYTOKINE; GAMMA INTERFERON; GRANULOCYTE MACROPHAGE COLONY STIMULATING FACTOR; GROWTH REGULATED PROTEIN; INTERLEUKIN 1; INTERLEUKIN 3; INTERLEUKIN 7; MONOCYTE CHEMOTACTIC PROTEIN 3; MONOKINE; PROTEIN; UNCLASSIFIED DRUG;

ADULT; ARTICLE; AUTOIMMUNE DISEASE; BLOOD SAMPLING; CONTROLLED STUDY; CYTOKINE PRODUCTION; CYTOKINE RELEASE; DIABETIC PATIENT; FAMILY HISTORY; FEMALE; GENOTYPE; HUMAN; HUMAN CELL; IMMUNE RESPONSE; IMMUNE SYSTEM; IMMUNOREACTIVITY; INSULIN DEPENDENT DIABETES MELLITUS; LYMPHOCYTE ACTIVATION; MALE; NEWBORN; NEWBORN PERIOD; PARENT; PATHOGENESIS; PRIORITY JOURNAL; PROTEIN MICROARRAY; RISK ASSESSMENT; UMBILICAL CORD BLOOD;

AUTOANTIGENS; AUTOIMMUNITY; CYTOKINES; DIABETES MELLITUS, TYPE 1; FEMALE; FETAL BLOOD; HUMANS; INFANT, NEWBORN; LEUKOCYTES, MONONUCLEAR; MALE; PEDIGREE; POLYMERASE CHAIN REACTION; PROTEIN ARRAY ANALYSIS;

EID: 35348959974     PISSN: 03009475     EISSN: 13653083     Source Type: Journal    
DOI: 10.1111/j.1365-3083.2007.01998.x     Document Type: Article

References (34)

1. Cinek O, Sumnik Z, Vavrinec J. Continuing increase in incidence of childhood-onset type 1 diabetes in the Czech Republic 1990-2001. Eur J Pediatr 2003 162 : 428 9.
2. Cinek O, Lanska V, Kolouskova S et al. Type 1 diabetes mellitus in Czech children diagnosed in 1990-1997: a significant increase in incidence and male predominance in the age group 0-4 years. Collaborators of the Czech Childhood Diabetes Registry. Diabet Med 2000 17 : 64 9.
3. Cinek O, Sumnik Z, Vavrinec J. Childhood diabetes in the Czech Republic: a steady increase in incidence. Cas Lek Cesk 2005 144 : 266 71.
4. Malcova H, Sumnik Z, Drevinek P et al. Absence of breast-feeding is associated with the risk of type 1 diabetes: a case-control study in a population with rapidly increasing incidence. Eur J Pediatr 2006 165 : 114 9.
5. Castano L, Eisenbarth GS. Type-I diabetes: a chronic autoimmune disease of human, mouse, and rat. Annu Rev Immunol 1990 8 : 647 79.
6. Foulis AK, Farquharson MA, Meager A. Immunoreactive a-interferon in insulin-secreting b cells in type 1 diabetes mellitus. Lancet 1987 2 : 1423 7.
7. Atkinson MA, Kaufman DL, Campbell L et al. Response of peripheral-blood mononuclear cells to glutamate decarboxylase in insulin-dependent diabetes. Lancet 1992 339 : 458 9.
8. Huang X, Yuan J, Goddard A et al. Interferon expression on the pancreases of patients with type I diabetes. Diabetes 1995 44 : 658 64.
9. Foulis AK, McGill M, Farquharson MA. Insulitis in type 1 (insulin-dependent) diabetes mellitus in man - macrophages, lymphocytes, and interferon-g containing cells. J Pathol 1991 165 : 97 103.
10. Karlsson MGE, Sederholm Lawesson S, Ludvigsson J. Th1-like dominance in high-risk first-degree relatives of type 1 diabetic patients. Diabetologia 2000 43 : 742 9.
11. Karlsson Faresjö MGE, Ludvigsson J. Diminished Th1-like response to autoantigens in children with a high risk of developing type 1 diabetes. Scand J Immunol 2005 61 : 173 9.
12. Hedman M, Ludvigsson J, Karlsson Faresjö MGE. Nicotinamide reduces secretion of IFN-g response in high-risk relatives of type 1 diabetic patients. J Interferon Cytokine Res 2006 26 : 207 13.
13. Halminen M, Simell O, Knip M et al. Cytokine expression in unstimulated PBMC of children with type 1 diabetes and subjects positive for diabetes-associated antibodies. Scand J Immunol 2001 53 : 510 3.
14. Lohmann T, Laue S, Nietzschmann U et al. Reduced experession of Th1-associated chemokine receptors on peripheral blood lymphocytes at diagnosis of type 1 diabetes. Diabetes 2002 51 : 2474 80.
15. Karlsson Faresjö M, Ernerudh E, Ludvigsson J. Cytokine profile in children during the first 3 months after the diagnosis of type 1 diabetes. Scand J Immunol 2004 59 : 517 26.
16. Krejsek J, Kopecky O. Clinical immunology. Hradec Kralove : Nucleus HK, 2004.
17. Maccario R, Ugazio AG. Cell mediated cytotoxicity in the neonate. In : Xanthou M, Bracii R, Prindull G, eds. Neonatal Immunology and Haematology II. Amsterdam : Elsevier Science Publishers, 1993 : 135 9.
18. Prindull G. The ontogeny of the hemato-lymphopoietic system including the mucosa associated lymphatic tissues (MALT) in human embryonal development. In : Xanthou M, Bracii R, Prindull G, eds. Neonatal Immunology and Haematology II. Amsterdam : Elsevier Science Publishers, 1993 : 177 85.
19. Faas MM, Bouman A, Van Nieuwenhoven ALV et al. Species differences in the effect of pregnancy on lymphocyte cytokine production between human and rat. J Leukoc Biol 2005 78 : 946 53.
20. Bowen JM, Chamley L, Keelan JA et al. Cytokines of the placenta and extra-placental membranes: roles and regulation during human pregnancy and parturition. Placenta 2002 23 : 257 73.
21. Kumru S, Boztosun A, Godekmerdan A. Pregnancy-associated changes in peripheral blood lymphocyte subpopulations and serum cytokine concentrations in healthy women. J Reprod Med Obstet Gynaecol 2005 50 : 246 50.
22. Piccinni M-P, Scaletti C, Maggi E et al. Role of hormone-controlled Th1- and Th2-type cytokines in successful pregnancy. J Neuroimmunol 2000 109 : 30 3.
23. Utz PJ. Protein arrays for studying blood cells and their secreted products. Immunol Rev 2005 204 : 264 82.
24. Cinek O, Kolouskova S, Pechova M et al. Prediction of insulin-dependent diabetes mellitus in first - degree relatives of diabetic patients. Cas Lek Cesk 2001 140 : 492 6.
25. Tsunoda M, Litonjua AA, Kuniak MP et al. Serum cytokine levels, cigarette smoking and airway responsiveness among pregnant women. Int Arch Allergy Immunol 2003 130 : 158 64.
26. Skornicka EL, Kiyatkina N, Weber MC et al. Pregnancy zone protein is a carrier and modulator of placental protein-14 in T-cell growth and cytokine production. Cell Immunol 2004 232 : 144 56.
27. McCracken SA, Gallery E, Morris JM. Pregnancy-specific down-regulation of NF-kappaB expression in T cells in humans is essential for the maintenance of the cytokine profile required for pregnancy success. J Immunol 2004 172 : 4583 91.
28. Athanassakis I, Vassiliadisy S. Interplay between T helper type 1 and type 2 cytokines and soluble major histocompatibility complex molecules: a paradigm in pregnancy. Immunology 2002 107 : 281 7.
29. Al-Shammri S, Rawoot P, Azizieh F et al. Th1/Th2 cytokine patterns and clinical profiles during and after pregnancy in women with multiple sclerosis. J Neurol Sci 2004 222 : 21 7.
30. Muñoz-Valle JF, Vazquez-Del Mercado M, Garcia-Iglesias T et al. TH1/TH2 cytokine profile, metalloprotease-9 activity and hormonal status in pregnant rheumatoid arthritis and systemic lupus erythematosus patients. Clin Exp Immunol 2003 131 : 377 84.
31. Ostensen M, Villiger PM. Immunology of pregnancy - pregnancy as a remission inducing agent in rheumatoid arthritis. Transpl Immunol 2001 9 : 155 60.
32. An H, Nishimaki S, Ohyama M et al. Interleukin-6, interleukin-8, and soluble tumor necrosis factor receptor-I in the cord blood as predictors of chronic lung disease in premature infants. Am J Obstet Gynecol 2004 191 : 1649 54.
33. Macaubas C, de Klerk NH, Holt BJ et al. Association between antenatal cytokine production and the development of atopy and asthma at age 6 years. Lancet 2003 362 : 1192 7.
34. Andersson U, Andersson J, Lindfors A et al. Restricted cytokine production by cord blood mononuclear cells. In : Xanthou M, Bracii R, Prindull G, eds. Neonatal Haematology and Immunology. Amsterdam : Elsevier Science Publishers, 1990 : 141 7.