Psychiatric and behavioral disorders in persons with down syndrome

Mental Retardation and Developmental Disabilities Research Reviews

Volumn 13, Issue 3, 2007, Pages 272-278

  Dykens, Elisabeth M ^a  

^a VANDERBILT UNIVERSITY MEDICAL CENTER   (United States)

Author keywords

Behavioral problem; Down syndrome; Psychiatric illness; Psychopathology; Risk and protective factors

Indexed keywords

ADOLESCENCE; ADOLESCENT DISEASE; ADULT DISEASE; ANXIETY; ATTENTION; BEHAVIOR DISORDER; CHILDHOOD DISEASE; DEPRESSION; DISEASE ASSOCIATION; DISTRESS SYNDROME; DOWN SYNDROME; HUMAN; MENTAL DISEASE; PREVALENCE; PRIORITY JOURNAL; REVIEW; RISK FACTOR; SOCIAL BEHAVIOR; WELLBEING;

ADOLESCENT; ADULT; AFFECTIVE SYMPTOMS; AGE FACTORS; AGE OF ONSET; ALZHEIMER DISEASE; CHILD; CHILD BEHAVIOR DISORDERS; DEPRESSION; DOWN SYNDROME; EVIDENCE-BASED MEDICINE; HUMANS; MENTAL HEALTH; PSYCHIATRIC STATUS RATING SCALES;

EID: 35348940663     PISSN: 10804013     EISSN: 10982779     Source Type: Journal    
DOI: 10.1002/mrdd.20159     Document Type: Review

References (73)

1. Abbeduto L, Pavetto M, Kesin E, et al. 2001. The linguistic and cognitive profile of Down syndrome: Evidence from a comparison with fragile X syndrome. Down Syndr: Res Pract 7:9-15.
2. Aisen PS, Dalton AJ, Sano M, et al. 2005. Design and implementation of a multicenter trial of vitamin E in aging individuals with Down syndrome. J Policy Pract Intellect Disabil 2:86-93.
3. Alyward EH, Burt DB, Thorpe LU, et al. 1997. Diagnosis of dementia on individuals with intellectual disability. J Intellect Disabil Res 41:152-164.
4. Ball SL, Holland AJ, Hon J, et al. 2006. Personality and behaviour changes mark the early stages of Alzheimer's disease in adults with Down's syndrome: findings from a prospective population-based study. Int J Geriatr Psychiatry 21:661-673.
5. Benson BA, Havercamp SM. 2007. Behavioural approaches to treatment: principles and practices. In: Bouras N, Holt G, editors. Psychiatric and behavioral disorders in intellectual and developmental disabilities, second edition. Cambridge: Cambridge University Press. p 283-309.
6. Burt DB, Loveland KA, Lewis KR. 1992. Depression and the onset of dementia in adults with mental retardation. Am J Ment Retard 96:502-511.
7. Capone GT, Grados MA, Kaufman WE, et al. 2005. Down syndrome and co-morbid autism spectrum disorder: characterization using the aberrant behavior checklist. Am J Med Genet 143:373-380.
8. Carter JC, Capone GT, Gray RM, et al. 2007. Autistic spectrum disorders in Down syndrome: further delineation and distinction from other behavioral abnormalities. Am J Med Genet B 144:87-94.
9. Coe DA, Matson JL, Russell D, et al. 1999. Behavior problems of children with Down syndrome and life events. J Autism Dev Disord 29:149-156.
10. Collacott RA, Cooper SA, McGrother C. 1992. Differential rates of psychiatric disorders in adults with Down's syndrome compared with other mentally handicapped adults. Br J Psychiatry 161:671-674.
11. Charlot L, Fox S, Friedlander R. 2002. Obsessional slowness in Down's syndrome. J Intellect Disabil Res 46:517-524.
12. Clark S, Schwalbe J, Stasko MR, et al. 2006. Fluoxetine rescues deficient neurogenesis in the hippocampus of the Ts65Dn mouse model for Down syndrome. Exp Neurol 2220:256-261.
13. Cooper SA, Duggirala C, Collacott RA. 1995. Adaptive behaviour after schizophrenia in people with Down's syndrome. J Intellect Disabil Res 39:201-204.
14. Cooper SA, Prasher VP. 1998. Maladaptive behaviors and symptoms of dementia in adults with Down's syndrome compared with adults with intellectual disability of other etiologies. J Intellect Disabil Res 42:293-300.
15. Craddock N, Owen M. 1994. Is there and inverse relationship between Down's syndrome ad bipolar affective disorder? Literature review and genetic implications. J Intellect Disabil Res 38:613-620.
16. Cuskelly M, Dadds M. 1992. Behavioural problems in children with Down syndrome and their siblings. J Child Psychol Psychiatry 33:749-761.
17. Dykens EM. 2000. Psychopathology in children with intellectual disability. J Child Psychol Psychiatry 41:407-417.
18. Dykens EM. 2003. Anxiety, fears and phobias in persons with Williams syndrome. Dev Neuropsychol 23:291-316.
19. Dykens EM. 2006. Toward a positive psychology of mental retardation. Am J Orthopsychiatr 76:185-193.
20. Dykens EM, Kasari C. 1997. Maladaptive behavior in children with Prader-Willi syndrome, Down syndrome, and non-specific mental retardation. Am J Ment Retard 102:228-237.
21. Dykens EM, Shah B, Sagun J, et al. 2002. Maladaptive behavior in children and adolescents with Down's syndrome. J Intellect Disabil Res 46:484-492.
22. Einfeld SL, Tonge BJ. 1996. Population prevalence of psychopathology in children and adolescents with intellectual disabilities. II. Epidemiological findings. J Intellect Disabil Res 40:99-109.
23. Esbensen AJ, Seltzer MM, Krauss MW. 2007. Stability and change in health, functional abilities and behavior problems among adults with and without Down syndrome. Under review.
24. Fidler DJ, Hodapp RM. 1999. Craniofacial maturity and perceived personality in children with Down syndrome. Am J Ment Retard 104:410-421.
25. Fishler K, Koch R. 1991. Mental development in Down syndrome mosaiciasm. Am J Ment Retard 96:345-351.
26. Fletcher R, Loschen E, Stavrakaki C, et al., editors. 2007. Diagnostic Manual-Intellectual Disability: a textbook of diagnosis of mental disorders in persons with intellectual disability. Kingston, NY: NADD.
27. Gath A, Gumley D. 1986. Behavior problems in retarded children with special reference to Down's syndrome. Br J Psychiatry 149:156-161.
28. Geldmacher DS, Lerner AJ, Voci JM, et al. 1997. Treatment of functional decline in adults with Down syndrome using selective serotonin-reuptake inhibitor drugs. J Geriatr Psychiatr Neurol 10:99-104.
29. Ghaziuddin M. 2000. Autism in Down's syndrome: a family history study. J Intellect Disabil Res 44:562-566.
30. Gibbs MV, Thorne JG. 1983. Personality stereotype of noninstitutionalized Down syndrome children. Am J Ment Defic 87:156-161.
31. Harvey MT, Kennedy CH. 2002. Polysomnographic phenotypes in developmental disabilities. Int J Dev Neurosci 20:443-448.
32. Hodapp RM, Dykens EM. 2005. Problems of girls and young women with mental retardation. In: Bell-Dolan D, Foster S, Mash E, editors. Handbook of emotional and behavioral disorders in girls. New York: Kluwer Academic. p 239-262.
33. Hodapp RM, Kazemi-Adzhyan E, Rosner BA, et al. 2006. Adolescents with mental retardation: A new frontier for dual diagnosis work? In: Wolf DA, Mash EJ, editors. Behavioral and emotional disorders in adolescents. New York: Guilford. p 383-409.
34. Hodapp RM, Ricci L, Ly T, et al. 2003. The effects of the child with Down syndrome on maternal stress. Br J Dev Psychol 22:137-151.
35. Holland AJ, Hon J, Huppert FA, et al. 1998. Population-based study of the prevalence and presentation of dementia in adults with Down's syndrome. Br J Psychiatry 172:494-498.
36. Holland AJ, Hon J, Huppert FA, et al. 2000. Prevalence and course of dementia in people with Down's syndrome: findings from a population-based study. J Intellect Disabil Res 44:138-146.
37. Hornby G. 1995. Father's views of the effects on their families of children with Down syndrome. J Child Fam Stud 4:103-117.
38. Hurley AD. 1989. Individual psychotherapy with mentally retarded individuals: a review and call for research. Res Dev Disabil 10:261-275.
39. Kasari C, Freeman SFN. 2001. Task-related social behavior in children with Down syndrome. Am J Ment Retard 106:253-264.
40. Kasari C, Freeman SFN, Mundy P, et al. 1995. Attention regulation by children with Down syndrome: coordinated joint attention and social referencing. Am J Ment Retard 100:12-136.
41. Kent L, Evans J, Paul M, et al. 1999. Comorbidity of autistic spectrum disorders in children with Down syndrome. Dev Med Child Neurol 41:153-158.
42. Lott IT, Head E. 2001. Down syndrome and Alzheimer's disease: a link between development and aging. Ment Retard Dev Disabil Res Rev 7:172-178.
43. Lund J. 1988. The presence of psychiatric morbidity in mentally retarded adults. Acta Psychiatr Scand 72:563-570.
44. Menolascino FJ. 1965. Psychiatric aspects of mongolism. Am J Ment Defic Res 69:653-660.
45. Meyers BA, Puschel SM. 1991. Psychiatric disorders in persons with Down syndrome. J Nerv Ment Dis 179:609-613.
46. Meyers BA, Pueschel SM. 1995. Major depression in a small groups of adults with Down syndrome. Res Dev Disabil 16:285-299.
47. Pary RJ, Hurley AD. 2002. Down syndrome and autistic disorder. Mental Health Asp Dev Disabil 5:64-65.
48. Patti P, Amble KB, Flory MJ. 2005. Life events in older adults with intellectual disabilities: differences between adults with and without Down syndrome. J Policy Pract Intellect Disabil 2:149-155.
49. Patti P, Tsiouris J. 2003. Emotional and behavioral disturbances in adults with Down syndrome. In: Davidson PW, Prasher VP, Janicki MP, editors. Mental health, intellectual disabilities and the aging process. Oxford, UK: Blackwell. p 81-94.
50. Pitcairn TK, Wishart JG. 1994. Reactions of young children with Down syndrome to an impossible task. Br J Dev Psychol 12:485-489.
51. Prasher VP, Day S. 1995. Obsessive-compulsive disorder in adults with Down's syndrome. J Autism Dev Disord 25:453-458.
52. Prasher VP, Huxley A, Haque MS, et al. 2002. A 24-week, double-blind, placebo-controlled trial of donepezil in patients with Down syndrome and Alzheimer's disease-Pilot study. Int J Geriatr Psychiatry 17:270-278.
53. Pueschel SM, Bernier JC, Pezullo JC. 1991. Behavioral observations of children with Down syndrome. J Mental Defic Res 35:502-511.
54. Rasmussen P, Borjesson O, Wentz E, et al. 2001. Autistic disorders in Down syndrome: background factors and clinical correlates. Dev Med Child Neurol 43:750-754.
55. Reiss S. 1990. Prevalence of dual diagnosis in community based day programs in the Chicago metropolitan area. Am J Ment Retard 94:578-588.
56. Reiss S, Aman MG. 1989. Psychotropic medications and developmental disabilities: the international consensus handbook. Washington: AAID.
57. Reiss SS, Levitan GW, Szyszko J. 1982. Emotional disturbance and mental retardation: diagnostic overshadowing. Am J Ment Def 86:567-574.
58. Rutter M, Tizard J, Yule W, et al. 1976. Research report: Isle of Wright studies, 1964-1974. Psychol Med 6:313-332.
59. Seligman MEP, Rashid T, Parks AC. 2006. Positive psychotherapy. Am Psychol 61:774-788.
60. Shepperdson B. 1995. Two longitudinal studies of the abilities of people with Down's syndrome. J Intellect Disabil Res 39:419-431.
61. Starr EM, Berument SK, Tomlinds M, et al. 2005. Brief report: autism in individuals with Down syndrome. J Autism Dev Disord 35:665-673.
62. Stores R, Stores G, Fellows B, et al. 1998a. Daytime behavior problems and maternal distress in children with Down syndrome, their siblings, and non-intellectually disabled and other intellectually disabled peers. J Intellect Disabil Res 42:228-237.
63. Stores R, Stores G, Fellows B, et al. 1998b. A factor analysis of sleep problems and their psychological associations in children with Down's syndrome. J Appl Res Dev Disabil 11:345-354.
64. Summer K, Shah B, Dykens EM. 2007. Psychosis in young people with Down syndrome. Under review.
65. Szymanski L, King BH. 1999. Summary of the practice parameters for the assessment and treatment of children, adolescents, and adults with mental retardation and comorbid mental disorders. J Am Acad Child Adolesc Psychiatry 38:1606-1610.
66. Tukiainen E, Tuomisto J, Westermarck T, et al. 1980. Nature of lowered 5-hydroxytryptamine uptake by blood platelets of patients with Down syndrome. Acat Pharmacol Toxicol 47:365-370.
67. Tyrer F, McGrother CW, Thorp CF, et al. 2006. Physical aggression towards others in adults with learning disabilities: prevalence and associated factors. J Intellect Disabil Res 50:295-304.
68. U.S. Public Health Service. 2001. Closing the gap: A national blueprint for improving the health of individuals with mental retardation. Report of the Surgeon General's Conference on Health Disparities and Mental Retardation, Washington DC.
69. Ward L. 2004. Risk factors for Alzheimer's disease in Down syndrome. Int Rev Res Ment Retard 29:159-196.
70. Warren AC, Holroyd S, Folstein MF. 1989. Major depression in Down's syndrome. Br J Psychiatry 155:202-205.
71. Whitaker-Azmitia PM. (2001). Serotonin and brain development: role in human developmental diseases. Brain Res Bull 56:479-485.
72. Wiggs L, Stores G. 1996. Severe sleep disturbance and daytime challenging behaviour in children with severe learning disabilities. J Intellect Disabil Res 40:518-528.
73. Zigman WB, Schupf N, Zigamn A, et al. 1993. Aging and Alzheimer's disease in Down syndrome. Int Rev Res Ment Retard 19:41-70.