EMF effects on microcirculatory system

Environmentalist

Volumn 27, Issue 4, 2007, Pages 395-402

  Ohkubo, Chiyoji ^a   Okano, Hideyuki ^b   Ushiyama, Akira ^c   Masuda, Hiroshi ^c  

^a WORLD HEALTH ORGANIZATION   (Switzerland)

^b KYOTO UNIVERSITY   (Japan)

^c NATIONAL INSTITUTE OF PUBLIC HEALTH   (Japan)

Author keywords

Animals; EMF; In vivo; Microcirculation; SAR; SMF

Indexed keywords

ANIMAL; BRAIN; CARDIOVASCULAR SYSTEM; ELECTROMAGNETIC FIELD;

ANIMALIA;

EID: 35348927414     PISSN: 02511088     EISSN: None     Source Type: Journal    
DOI: 10.1007/s10669-007-9082-z     Document Type: Article

References (66)

1. Ahlbom, I. C., Cardis, E., Green, A., Linet, M., Savitz, D., & Swerdlow, A. (2001). Review of the epidemiologic literature on EMF and health. Environmental Health Perspectives, 109(Suppl 6), 911-933.
2. Asano, M., & Brånemark, P. I. (1972). Microphotoelectric plethysmography using a titanium chamber in man. In H. Harders (Ed.), Advances in microcirculation, (Vol. 4, pp. 131-160). Basel: S. Karger.
3. Asano, M., Yoshida, K., & Tatai, K. (1965). Microphotoelectric plethysmography using a rabbit ear chamber. Journal of Applied Physiology, 20, 1056-1062.
4. Aubineau, P., & Tore, F. (2005). Head exposure to 900 MHz microwaves induces plasma protein extravasation in the rat brain and dura mater at non-thermal SAR levels. In Monografie Workshops: Influences of RF- and electromagnetic field interaction. Berufsgenossenschaft der Feinmechanik und Elektrotechnik, pp. 82-83.
5. Cavopol, A. V., Wamil, A. W., Holcomb, R. R., & McLean, M. J. (1995). Measurement and analysis of static magnetic fields that block action potentials in cultured neurons. Bioelectromagnetics, 16, 197-206.
6. Engström, S., Markov, M. S., McLean, M. J., Holcomb, R. R., & Markov, J. M. (2002). Effects of non-uniform static magnetic fields on the rate of myosin phosphorylation. Bioelectromagnetics, 23, 475-479.
7. Finnie, J. W., Blumbergs, P. C., Cai, Z., Manavis, J., & Kuchel, T. R. (2006). Effect of mobile telephony on blood-brain barrier permeability in the fetal mouse brain. Pathology, 38, 63-65.
8. Franke, H., Streckert, J., Bitz, A., Goeke, J., Hansen, V., Ringelstein, E. B., Nattkamper, H., Galla, H. J., & Stogbauer, F. (2005). Effects of universal mobile telecommunications system (UMTS) electromagnetic fields on the blood-brain barrier in vitro. Radiation Research, 164, 258-269.
9. Fritze, K., Sommer, C., Schmitz, B., Mies, G., Hossmann, K. A., Kiessling, M., & Wiessner, C. (1997). Effect of global system for mobile communication (GSM) microwave exposure on blood-brain barrier permeability in rat. Acta Neuropathologica (Berl), 94, 465-470.
10. Fukumura, D. (2006). Window models. In D. Shepro (Ed.), Microvascular research: Biology and pathology (pp. 151-157). San Diego, CA, USA: Elsevier Science.
11. Funk, W., & Intaglietta, M. (1983). Spontaneous arteriolar vasomotion. In K. Messemer, & F. Hammersen (Eds.), Progress in applied microcirculation (Vol. 3, pp. 66-82). Basel: Karger.
12. Gaber, M. W., Yuan, H., Killmar, J. T., Naimark, M. D., Kiani, M. F., & Merchant, T. E. (2004). An intravital microscopy study of radiation-induced changes in permeability and leukocyte-endothelial cell interactions in the microvessels of the rat pia mater and cremaster muscle. Brain research. Brain Research Protocols, 13, 1-10.
13. Gmitrov, J., Ohkubo, C., & Okano, H. (2002). Effect of 0.25 T static magnetic field on microcirculation in rabbits. Bioelectromagnetics, 23, 224-229.
14. Hinman, M. R. (2002). Comparative effect of positive and negative static magnetic fields on heart rate and blood pressure in healthy adults. Clinical Rehabilitation, 16, 669-674.
15. House, R. V., & McCormick, D. L. (2000). Modulation of natural killer cell function after exposure to 60 Hz magnetic fields: Confirmation of the effect in mature B6C3F1 mice. Radiation Research, 153, 722-724.
16. House, R. V., Ratajczak, H. V., Gauger, J. R., Johnson, T. R., Thomas, P. T., & McCormick, D. L. (1996). Immune function and host defence in rodents exposed to 60-Hz magnetic fields. Fundamental and Applied Toxicology, 34, 228-239.
17. Ichioka, S., Minegishi, M., Iwasaka, M., Shibata, M., Nakatsuka, T., Ando, J., & Ueno, S. (2003). Skin temperature changes induced by strong static magnetic field exposure. Bioelectromagnetics, 24, 380-386.
18. Ichioka, S., Minegishi, M., Iwasaka, M., Shibata, M., Nakatsuka, T., Harii, K., Kamiya, A., & Ueno, S. (2000). High-intensity static magnetic fields modulate skin microcirculation and temperature in vivo. Bioelectromagnetics, 21, 183-188.
19. Jain, R. K. (1997). The Eugene M. Landis award lecture 1996 delivery of molecular and cellular medicine to solid tumors. Microcirculation, 4, 1-23.
20. Kangarlu, A., Burgess, R. E., Zhu, H., Nakayama, T., Hamlin, R. L., Abduljalil, A. M., & Robitaille, P. M. (1999). Cognitive, cardiac, and physiological safety studies in ultra high field magnetic resonance imaging. Magnetic Resonance Imaging, 17, 1407-1416.
21. Kuipers, N. T., Sauder, C. L., & Ray, C. A. (2006). Influence of static magnetic fields on pain perception and sympathetic nerve activity in humans. Journal of Applied Physiology, 102, 1410-1415.
22. Kuribayashi, M., Wang, J., Fujiwara, O., Doi, Y., Nabae, K., Tamano, S., Ogiso, T., Asamoto, M., & Shirai, T. (2005). Lack of effects of 1439 MHz electromagnetic near field exposure on the blood-brain barrier in immature and young rats. Bioelectromagnetics, 26, 578-588.
23. Markov, M. S., Williams, C. D., Cameron, I. L., Hardman, W. E., & Salvatore, J. R. (2004) Can magnetic fields inhibit angiogenesis and tumor growth? In P. J. Rosch, & M. S. Markov (Eds.), Bioelectromagnetic medicine (pp. 625-636). NY: Marcel Dekker Inc.
24. Martel, G. F., Andrews, S. C., & Roseboom, C. G. (2002). Comparison of static and placebo magnets on resting forearm blood flow in young, healthy men. The Journal of Orthopaedic and Sports Physical Therapy, 32, 518-524.
25. Masuda, H., Ushiyama, A., Okano, H., & Ohkubo, C. (2000). Chronological observation of the pial microcirculation using a chronically implanted cranial window method in the rat. In M. Tsuchiya, M. Asano, T. Tokioka, & K. Takahashi (Eds.), Microcirculation annual 2000 (pp.151-152). Tokyo: Nihon-Igakukan.
26. Masuda H., Hirota S., Ushiyama A., Wake K., Watanabe S., Taki M., & Ohkubo, C. (2003). In vivo evaluation of exposure effects to radio-frequency electromagnetic fields on the cerebral circulation in rats. Abstract book of the Blood-Brain Barrier (BBB) Workshop of COST281-Potential Health Implications From Mobile Communication Systems. Reisensburg, Germany, pp. 28-29.
27. Masuda H., Ushiyama A., Wake K., Watanabe S., Taki M., & Ohkubo C. (2001a). Acute effects of local exposure to radio-frequency electromagnetic fields on the cerebral microcirculation in rats. The 23rd Annual Meeting of Bioelectromagnetic Society Abstract Book, pp.139-140.
28. Masuda H., Ushiyama A., Wake K., Watanabe S., Taki M., & Ohkubo C. (2001b). Chronic effects of local exposure to radiofrequency electromagnetic fields on the cerebral microcirculation in rats. 2001 Asia-Pacific Radio Science Conference Digest, p.410.
29. Mayhan, W. G. (1998). Effect of lipopolysaccharide on the permeability and reactivity of the cerebral microcirculation: Role of inducible nitric oxide synthase. Brain Research, 792, 353-357.
30. Mayhan, W. G. (2000). Leukocyte adherence contributes to disruption of the blood-brain barrier during activation of mast cells. Brain Research, 869, 112-120.
31. Mayrovitz, H. N., Groseclose, E. E., & King, D. (2005). No effect of 85 mT permanent magnets on Laser-Doppler measured blood flow response to inspiratory gasps. Bioelectromagnetics, 26, 331-335.
32. Mayrovitz, H. N., Groseclose, E. E., Markov, M., & Pilla, A. A. (2001). Effects of permanent magnets on resting skin blood perfusion in healthy persons assessed by Laser Doppler Flowmetry and Imaging. Bioelectromagnetics, 22, 494-502.
33. McKay, J. C., Prato, F. S., & Thomas, A. W. (2007). A literature review: The effects of magnetic field exposure on blood flow and blood vessels in the microvasculature. Bioelectromagnetics, 28, 81-98.
34. McLean, M. J., Holcomb, R. R., Wamil, A. W., Pickett, J. D., & Cavopol, A. V. (1995). Blockade of sensory neuron action potentials by a static magnetic field in the 10 mT range. Bioelectromagnetics, 16, 20-32.
35. Morris, C., & Skalak, T. (2005) Static magnetic fields alter arteriolar tone in vivo. Bioelectromagnetics, 26, 1-9.
36. Mulvany, M. J. (1983). Functional characteristics of vascular smooth muscle. In K. Messemer, & F. Hammersen (Eds.) Progress in applied microcirculation (Vol. 3, pp. 4-18). Basel: Karger.
37. Ohkubo, C., & Okano, H. (2004). Static magnetic field and microcirculation. In P. J. Rosch, & M. S. Markov (Eds.), Bioelectromagnetic medicine, (pp. 563-591). NY: Marcel Dekker Inc.
38. Ohkubo, C., & Xu, S. (1997). Acute effects of static magnetic fields on cutaneous microcirculation in rabbits. In Vivo, 11, 221-225.
39. Okano, H., Gmitrov, J., & Ohkubo, C. (1999). Biphasic effects of static magnetic fields on cutaneous microcirculation in rabbits. Bioelectromagnetics, 20, 161-171.
40. Okano, H., Masuda, H., & Ohkubo, C. (2005a). Effects of 25 mT static magnetic field on blood pressure in reserpine-induced hypotensive wistar-kyoto rats. Bioelectromagnetics, 26, 36-48.
41. Okano, H., Masuda, H., & Ohkubo, C. (2005b). Decreased plasma levels of nitric oxide metabolites, angiotensin II and aldosterone in spontaneously hypertensive rats exposed to 5 mT static magnetic field. Bioelectromagnetics, 26, 161-172.
42. Okano, H., & Ohkubo, C. (2001). Modulatory effects of static magnetic fields on blood pressure in rabbits. Bioelectromagnetics, 22, 408-418.
43. Okano, H., & Ohkubo, C. (2003a). Anti-pressor effects of whole-body exposure to static magnetic field on pharmacologically induced hypertension in conscious rabbits. Bioelectromagnetics, 24, 139-147.
44. Okano, H., & Ohkubo, C. (2003b). Effects of static magnetic fields on plasma levels of angiotensin II and aldosterone associated with arterial blood pressure in genetically hypertensive rats. Bioelectromagnetics, 24, 403-412.
45. Okano, H., & Ohkubo, C. (2005a). Effects of neck exposure to 5.5 mT static magnetic field on pharmacologically modulated blood pressure in conscious rabbits. Bioelectromagnetics, 26, 469-480.
46. Okano, H., & Ohkubo, C. (2005b). Exposure to a moderate-intensity static magnetic field enhances the hypotensive effect of a calcium channel blocker in spontaneously hypertensive rats. Bioelectromagnetics, 26, 611-623.
47. Okano, H., & Ohkubo, C. (2006). Elevated plasma nitric oxide metabolites in hypertension: Synergistic vasodepressor effects of a static magnetic field and nicardipine in spontaneously hypertensive rats. Clinical Hemorheology and Microcirculation, 34, 303-308..
48. Okano, H., & Ohkubo, C. (2007). Effects of 12 mT static magnetic field on sympathetic agonist-induced hypertension and hemodynamic changes in wistar rats. Bioelectromagnetics, 28, 369-378.
49. Prato, F. S., Wills, J. M., Roger, J., Frappier, H., Drost, D. J., Lee, T. Y., Shivers, R. R., & Zabel, P. (1994). Blood-brain barrier permeability in rats is altered by exposure to magnetic fields associated with magnetic resonance imaging at 1.5 T. Microscopy Research and Technique, 27, 528-534.
50. Salford, L. G., Brun, A. E., Eberhardt, J. L., Malmgren, L., & Persson, B. R. (2003) Nerve cell damage in mammalian brain after exposure to microwaves from GSM mobile phones. Environ Health Perspect, 111, 881-883, discussion A408.
51. Salford, L. G., Brun, A., Sturesson, K., Eberhardt, J. L., & Persson, B. R. (1994). Permeability of the blood-brain barrier induced by 915 MHz electromagnetic radiation, continuous wave and modulated at 8, 16, 50, and 200 Hz. Microscopy Research and Technique, 27, 535-542.
52. Saunders, R. (2005). Static magnetic fields: Animal studies. Progress in Biophysics and Molecular Biology, 87, 225-239.
53. Schirmacher, A., Winters, S., Fischer, S., Goeke, J., Galla, H. J., Kullnick, U., Ringelstein, E. B., & Stogbauer F. (2000). Electromagnetic fields (1.8 GHz) increase the permeability to sucrose of the blood-brain barrier in vitro. Bioelectromagnetics, 21, 338-345.
54. Sharma, H.S., & Hoopes, P. J. (2003). Hyperthermia induced pathophysiology of the central nervous system. International Journal of Hyperthermia, 19, 325-354.
55. Shrivastav, S., Kaelin, W. G. Jr., Joines, W. T., & Jirtle, R. L. (1983). Microwave hyperthermia and its effect on tumor blood flow in rats. Cancer Research, 43, 4665-4669.
56. Steyn, P. F., Ramey, D. W., Kirschvink, J., & Uhrig, J. (2000). Effect of a static magnetic field on blood flow to the metacarpus in horses. Journal of the American Veterinary Medical Association, 217, 874-877.
57. Tenforde, T. S. (2005). Magnetically induced electric fields and currents in the circulatory system. Progress in Biophysics and Molecular Biology, 87, 279-288.
58. Tsurita, G., Nagawa, H., Ueno, S., Watanabe, S., & Taki, M. (2000). Biological and morphological effects on the brain after exposure of rats to a 1439 MHz TDMA field. Bioelectromagnetics, 21, 364-371.
59. Ushiyama, A., Masuda, H., & Ohkubo, C. (2003) Effects of subchronic exposure to extremely low frequency electromagnetic fields on tumor growth and angiogenesis in the mouse cranial window. In M. Asano, & S. Miura (Eds.), Microcirculation annual 2003 (pp. 101-102). Tokyo: Nihon-Igakukan.
60. Ushiyama, A., Yamada, S., & Ohkubo, C. (2004a). Microcirculatory parameters measured in subcutaneous tissue of the mouse using a novel dorsal skinfold chamber. Microvascular Research, 68, 147-152.
61. Ushiyama, A., Masuda, H., Hirota, S., & Ohkubo, C. (2004b). Subchronic effects on leukocyte-endothelial interactions in mice by whole body exposure to extremely low frequency electromagnetic fields. In Vivo 18, 425-432.
62. Ushiyama, A., & Ohkubo, C. (2004) Acute effects of low-frequency electromagnetic fields on leukocyte-endothelial interactions in vivo. In Vivo, 18, 125-132.
63. Waldman, W. J., & Knight, D. A. (1996). Cytokine-mediated induction of endothelial adhesion molecule and histocompatibility leukocyte antigen expression by cytomegalovirus- activated T cells. The American Journal of Pathology, 148, 105-119.
64. Xu, S, Okano, H., & Ohkubo, C. (1998) Subchronic effects of static magnetic fields on cutaneous microcirculation in rabbits. In Vivo, 12, 383-389.
65. Xu, S., Okano, H., & Ohkubo, C. (2000). Acute effects of whole-body exposure to static magnetic fields and 50-Hz electromagnetic fields on muscle microcirculation in anesthetized mice. Bioelectrochemistry, 53, 127-135.
66. Yuan, H., Gaber, M. W., McColgan, T., Naimark, M. D., Kiani, M. F., & Merchant, T. E. (2003). Radiation-induced permeability and leukocyte adhesion in the rat blood-brain barrier: Modulation with anti-ICAM-1 antibodies. Brain Research, 969, 59-69.