Subchronic effects on leukocyte-endothelial interactions in mice by whole body exposure to extremely low frequency electromagnetic fields

In Vivo

Volumn 18, Issue 4, 2004, Pages 425-432

  Ushiyama, Akira ^a   Masuda, Hiroshi ^a   Hirota, Shugo ^a   Ohkubo, Chiyoji ^a  

^a NATIONAL INSTITUTE OF PUBLIC HEALTH   (Japan)

Author keywords

Immunological response; Leukocyte endothelium interactions; Low frequency electromagnetic fields; Microcirculation; Mouse; Subchronic effect

Indexed keywords

CYTOKINE; INTERLEUKIN 1BETA; TUMOR NECROSIS FACTOR ALPHA;

ANIMAL CELL; ARTICLE; CELL INTERACTION; ELECTROMAGNETIC FIELD; FLUORESCENCE MICROSCOPY; IN VITRO STUDY; IN VIVO STUDY; LEUKOCYTE ADHERENCE; LONG TERM EXPOSURE; MALE; MICROCIRCULATION; MOUSE; NONHUMAN; SKINFOLD; SUBCUTANEOUS TISSUE; VASCULAR ENDOTHELIUM;

EID: 4444237855     PISSN: 0258851X     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (28)

1. Repacholi MH and Greenebaum B: Interaction of static and extremely low frequency electric and magnetic fields with living systems: health effects and research needs. Bioelectromagnetics 20: 133-60, 1999.
2. Ahlbom A, Day N, Feychting M, Roman E, Skinner J, Dockerty J, Linet M, McBride M, Michaelis J, Olsen JH, Tynes T and Verkasalo PK: A pooled analysis of magnetic fields and childhood leukaemia. Br J Cancer 83: 692-8, 2000.
3. Greenland S, Sheppard AR, Kaune WT, Poole C and Kelsh MA: A pooled analysis of magnetic fields, wire codes, and childhood leukemia. Childhood Leukemia-EMF Study Group. Epidemiology 11: 624-34, 2000.
4. Litovitz TA, Krause D and Mullins JM: Effect of coherence time of the applied magnetic field on ornithine decarboxylase activity. Biochem Biophys Res Commun 178: 862-5, 1991.
5. Goodman R, Blank M, Lin H, Dai R, Khorkova O, Soo L, Weisbrot D and Henderson A: Increased levels of hsp70 transcripts induced when cells are exposed to low frequency electromagnetic fields. Bioelectrochem Bioenerg 33: 115-20, 1994.
6. Miyakoshi J, Mori Y, Yaguchi H, Ding G and Fujimori A: Suppression of heat-induced HSP-70 by simultaneous exposure to 50 mT magnetic field. Life Sci 66: 1187-96, 2000.
7. Cho YH and Chung HW: The effect of extremely low frequency electromagnetic fields (ELF-EMF) on the frequency of micronuclei and sister chromatid exchange in human lymphocytes induced by benzo(a)pyrene. Toxicol Lett 143: 37-44, 2003.
8. Wetzel BJ, Nindl G, Vesper DN, Swez JA, Jasti AC and Johnson MT: Electromagnetic field effects: changes in protein phosphorylation in the Jurkat E6.1 cell line. Biomed Sci Instrum 37: 203-8, 2001.
9. Arafa HM, Abd-Allah AR, El-Mahdy MA, Ramadan LA and Hamada FM: Immunomodulatory effects of L-carnitine and q10 in mouse spleen exposed to low-frequency high-intensity magnetic field. Toxicology 187: 171-81, 2003.
10. Marino AA, Wolcott RM, Chervenak R, Jourd'heuil F, Nilsen E and Frilot C 2nd: Nonlinear determinism in the immune system. In vivo influence of electromagnetic fields on different functions of murine lymphocyte subpopulations. Immunol Invest 30: 313-34, 2001.
11. Felaco M, Reale M, Grilli A, De Lutiis MA, Barbacane RC, Di Luzio S and Conti P: Impact of extremely low frequency electromagnetic fields on CD4 expression in peripheral blood mononuclear cells. Mol Cell Biochem 201: 49-55, 1999.
12. Jonai H, Villanueva MB and Yasuda A: Cytokine profile of human peripheral blood mononuclear cells exposed to 50 Hz EMF. Ind Health 34: 359-68, 1996.
13. Hefeneider SH, McCoy SL, Hausman FA, Christensen HL, Takahashi D, Perrin N, Bracken TD, Shin KY and Hall AS: Long-term effects of 60-Hz electric vs. magnetic fields on IL-1 and IL-2 activity in sheep. Bioelectromagnetics 22: 170-7, 2001.
14. Spertini O, Luscinskas FW, Kansas GS, Munro JM, Griffin JD, Gimbrone MA Jr and Tedder TF: Leukocyte adhesion molecule-1 (LAM-1, L-selectin) interacts with an inducible endothelial cell ligand to support leukocyte adhesion. J Immunol 147: 2565-73, 1991.
15. Jain RK, Munn LL and Fukumura D: Dissecting tumour pathophysiology using intravital microscopy. Nat Rev Cancer 2: 266-76, 2002.
16. Jain RK: The next frontier of molecular medicine: delivery of therapeutics. Nat Med 4: 655-7, 1998.
17. Algire GH and Legallais FY: Recent developments in the transparent-chamber technique as adopted to the mouse. J Nat Cancer Inst 10: 225-253, 1949.
18. Leunig M, Yuan F, Menger MD, Boucher Y, Goetz AE, Messmer K and Jain RK: Angiogenesis, microvascular architecture, microhemodynamics, and interstitial fluid pressure during early growth of human adenocarcinoma LS174T in SCID mice. Cancer Res 52: 6553-60, 1992.
19. Baatz H, Steinbauer M, Harris AG and Krombach F: Kinetics of white blood cell staining by intravascular administration of rhodamine 6G. Int J Microcirc Clin Exp 15: 85-91, 1995.
20. Suzuki T, Yanagi K, Ookawa K, Hatakeyama K and Ohshima N: Flow visualization of microcirculation in solid tumor tissues: intravital microscopic observation of blood circulation by use of a confocal laser scanning microscope. Front Med Biol Eng 7: 253-63, 1996.
21. Yamaguchi K: Observation of microcirculatory kinetics by real-time confocal laser scanning microscopy. Methods Enzymol 307: 394-422, 1999.
22. Haraldsen G, Kvale D, Lien B, Farstad IN and Brandtzaeg P: Cytokine-regulated expression of E-selectin, intercellular adhesion molecule-1 (ICAM-1), and vascular cell adhesion molecule-1 (VCAM-1) in human microvascular endothelial cells. J Immunol 156: 2558-65, 1996.
23. Waldman WJ and Knight DA: Cytokine-mediated induction of endothelial adhesion molecule and histocompatibility leukocyte antigen expression by cytomegalovirus-activated T cells. Am J Pathol 148: 105-19, 1996.
24. Silverman MD, Zamora DO, Pan Y, Texeira PV, Planck SR and Rosenbaum JT: Cell adhesion molecule expression in cultured human iris endothelial cells. Invest Ophthalmol Vis Sci 42: 2861-6, 2001.
25. Cossarizza A, Angioni S, Petraglia F, Genazzani AR, Monti D, Capri M, Bersani F, Cadossi R and Franceschi C: Exposure to low frequency pulsed electromagnetic fields increases interleukin-1 and interleukin-6 production by human peripheral blood mononuclear cells. Exp Cell Res 204: 385-7, 1993.
26. Perini C, Dupuis M, Polichetti A, Romani C and Vecchia P: Tumor necrosis factor and interferon production by human peripheral blood mononuclear cells exposed in vitro to sinusoidal 50 Hz magnetic fields. Bioelectrochem Bioenerg 44: 121-5, 1997.
27. Ikeda K, Shinmura Y, Mizoe H, Yoshizawa H, Yoshida A, Kanao S, Sumitani H, Hasebe S, Motomura T, Yamakawa T, Mizuno F, Otaka Y and Hirose H: No effects of extremely low frequency magnetic fields found on cytotoxic activities and cytokine production of human peripheral blood mononuclear cells in vitro. Bioelectromagnetics 24: 21-31, 2003.
28. Sato T, Miwa T, Akatsu H, Matsukawa N, Obata K, Okada N, Campbell W and Okada H: Pro-carboxypeptidase R is an acute phase protein in the mouse, whereas carboxypeptidase N is not. J Immunol 165: 1053-8, 2000.