메뉴 건너뛰기




Volumn 8, Issue 9, 2007, Pages 1101-1104

Genetic testing to provide targeted treatment for cystic fibrosis patients

Author keywords

[No Author keywords available]

Indexed keywords

AMINOGLYCOSIDE ANTIBIOTIC AGENT; ANTIBIOTIC AGENT; CYCLIC AMP DEPENDENT PROTEIN KINASE; GENTAMICIN; MESSENGER RNA; NEGAMYCIN; PTC 124; TRANSMEMBRANE CONDUCTANCE REGULATOR; UNCLASSIFIED DRUG;

EID: 35348926322     PISSN: 14622416     EISSN: 17448042     Source Type: Journal    
DOI: 10.2217/14622416.8.9.1101     Document Type: Editorial
Times cited : (1)

References (18)
  • 1
    • 34247609987 scopus 로고    scopus 로고
    • Chemical biology: Ignore the nonsense
    • Schmitz A, Famulok M: Chemical biology: ignore the nonsense. Nature 447(7140), 42-43 (2007).
    • (2007) Nature , vol.447 , Issue.7140 , pp. 42-43
    • Schmitz, A.1    Famulok, M.2
  • 2
    • 33847360602 scopus 로고    scopus 로고
    • Nonsense-mediated mRNA decay affects nonsense transcript levels and governs response of cystic fibrosis patients to gentamicin
    • Linde L, Boelz S, Nissim-Rafinia M et al.: Nonsense-mediated mRNA decay affects nonsense transcript levels and governs response of cystic fibrosis patients to gentamicin. J. Clin. Invest. 117(3), 683-692 (2007).
    • (2007) J. Clin. Invest , vol.117 , Issue.3 , pp. 683-692
    • Linde, L.1    Boelz, S.2    Nissim-Rafinia, M.3
  • 5
    • 33750117540 scopus 로고    scopus 로고
    • Cystic fibrosis enters the proteomics scene: New answers to old questions
    • Ollero M, Brouillard F, Edelman A: Cystic fibrosis enters the proteomics scene: new answers to old questions. Proteomics 6(14), 4084-4099 (2006).
    • (2006) Proteomics , vol.6 , Issue.14 , pp. 4084-4099
    • Ollero, M.1    Brouillard, F.2    Edelman, A.3
  • 6
    • 10644294652 scopus 로고    scopus 로고
    • Global proteomic approach unmasks involvement of keratins 8 and 18 in the delivery of cystic fibrosis transmembrane conductance regulator (CFTR)/ deltaF508-CFTR to the plasma membrane
    • Davezac N, Tondelier D, Lipecka J et al.: Global proteomic approach unmasks involvement of keratins 8 and 18 in the delivery of cystic fibrosis transmembrane conductance regulator (CFTR)/ deltaF508-CFTR to the plasma membrane. Proteomics 4(12), 3833-3844 (2004).
    • (2004) Proteomics , vol.4 , Issue.12 , pp. 3833-3844
    • Davezac, N.1    Tondelier, D.2    Lipecka, J.3
  • 7
    • 34247200483 scopus 로고    scopus 로고
    • In vitro prediction of stop-codon suppression by intravenous gentamicin in patients with cystic fibrosis: A pilot study
    • Sermet-Gaudelus I, Renouil M, Fajac A et al.: In vitro prediction of stop-codon suppression by intravenous gentamicin in patients with cystic fibrosis: a pilot study. BMC Med. 5, 5 (2007).
    • (2007) BMC Med , vol.5 , pp. 5
    • Sermet-Gaudelus, I.1    Renouil, M.2    Fajac, A.3
  • 8
    • 7444230353 scopus 로고    scopus 로고
    • Pharmacologic therapy for stop mutations: How much CFTR activity is enough?
    • Kerem E: Pharmacologic therapy for stop mutations: how much CFTR activity is enough? Curr. Opin. Pulm. Med. 10(6), 547-552 (2004).
    • (2004) Curr. Opin. Pulm. Med , vol.10 , Issue.6 , pp. 547-552
    • Kerem, E.1
  • 9
    • 0029994529 scopus 로고    scopus 로고
    • Aminoglycoside antibiotics restore CFTR function by overcoming premature stop mutations
    • Howard M, Frizzell RA, Bedwell DM: Aminoglycoside antibiotics restore CFTR function by overcoming premature stop mutations. Nat. Med. 2(4), 467-469 (1996).
    • (1996) Nat. Med , vol.2 , Issue.4 , pp. 467-469
    • Howard, M.1    Frizzell, R.A.2    Bedwell, D.M.3
  • 10
    • 0033929810 scopus 로고    scopus 로고
    • Aminoglycoside antibiotics mediate context-dependent suppression of termination codons in a mammalian translation system
    • Manuvakhova M, Keeling K, Bedwell DM: Aminoglycoside antibiotics mediate context-dependent suppression of termination codons in a mammalian translation system. RNA 6(7), 1044-1055 (2000).
    • (2000) RNA , vol.6 , Issue.7 , pp. 1044-1055
    • Manuvakhova, M.1    Keeling, K.2    Bedwell, D.M.3
  • 11
    • 34247588271 scopus 로고    scopus 로고
    • PTC124 targets-genetic disorders caused by nonsense mutations
    • Welch EM, Barton ER, Zhuo J et al.: PTC124 targets-genetic disorders caused by nonsense mutations. Nature 447 (7140), 87-91 (2007).
    • (2007) Nature , vol.447 , Issue.7140 , pp. 87-91
    • Welch, E.M.1    Barton, E.R.2    Zhuo, J.3
  • 12
    • 0034779875 scopus 로고    scopus 로고
    • Impact of the six nucleotides downstream of the stop codon on translation termination
    • 29, 787-793
    • Namy O, Hatin I, Rousset JP: Impact of the six nucleotides downstream of the stop codon on translation termination. EMBO Rep. 2(9), 787-793 (2001).
    • (2001) EMBO Rep
    • Namy, O.1    Hatin, I.2    Rousset, J.P.3
  • 13
    • 0034961464 scopus 로고    scopus 로고
    • Evidence that systemic gentamicin suppresses premature stop mutations in patients with cystic fibrosis
    • Clancy JP, Bebok Z, Rutz F et al.: Evidence that systemic gentamicin suppresses premature stop mutations in patients with cystic fibrosis. Am. J. Respir. Crit. Care Med. 163(7), 1683-1692 (2001).
    • (2001) Am. J. Respir. Crit. Care Med , vol.163 , Issue.7 , pp. 1683-1692
    • Clancy, J.P.1    Bebok, Z.2    Rutz, F.3
  • 14
    • 1842586020 scopus 로고    scopus 로고
    • Premature stop codons involved in muscular dystrophies show a broad spectrum of readthrough efficiencies in response to gentamicin treatment
    • Bidou L, Hatin I, Perez N, Allamand V, Panthier JJ, Rousset JP: Premature stop codons involved in muscular dystrophies show a broad spectrum of readthrough efficiencies in response to gentamicin treatment. Gene Ther. 11(7), 619-627 (2004).
    • (2004) Gene Ther , vol.11 , Issue.7 , pp. 619-627
    • Bidou, L.1    Hatin, I.2    Perez, N.3    Allamand, V.4    Panthier, J.J.5    Rousset, J.P.6
  • 15
    • 0030702773 scopus 로고    scopus 로고
    • Suppression of a CFTR premature stop mutation in a bronchial epithelial cell line
    • Bedwell DM, Kaenjak A, Benos DJ et al.: Suppression of a CFTR premature stop mutation in a bronchial epithelial cell line. Nat. Med. 3(11), 1280-1284 (1997).
    • (1997) Nat. Med , vol.3 , Issue.11 , pp. 1280-1284
    • Bedwell, D.M.1    Kaenjak, A.2    Benos, D.J.3
  • 16
    • 0036379141 scopus 로고    scopus 로고
    • -/- mouse carrying a human CFTR-G542X transgene
    • -/- mouse carrying a human CFTR-G542X transgene. J. Mol. Med. 80(9), 595-604 (2002).
    • (2002) J. Mol. Med , vol.80 , Issue.9 , pp. 595-604
    • Du, M.1    Jones, J.R.2    Lanier, J.3
  • 17
    • 0141863491 scopus 로고    scopus 로고
    • Gentamicin-induced correction of CFTR function in patients with cystic fibrosis and CFTR stop mutations
    • Wilschanski M, Yahav Y, Yaacov Y et al.: Gentamicin-induced correction of CFTR function in patients with cystic fibrosis and CFTR stop mutations. N. Engl. J. Med. 349(15), 1433-1441 (2003).
    • (2003) N. Engl. J. Med , vol.349 , Issue.15 , pp. 1433-1441
    • Wilschanski, M.1    Yahav, Y.2    Yaacov, Y.3
  • 18
    • 35348852923 scopus 로고    scopus 로고
    • No detectable improvements in CFTR by nasal aminoglycosides in CF patients with stop mutations
    • Clancy JP, Rowe SM, Bebok Z et al.: No detectable improvements in CFTR by nasal aminoglycosides in CF patients with stop mutations. Am. J. Respir. Cell Mol. Biol. (2007).
    • (2007) Am. J. Respir. Cell Mol. Biol
    • Clancy, J.P.1    Rowe, S.M.2    Bebok, Z.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.