메뉴 건너뛰기




Volumn 21, Issue , 2007, Pages 3-12

Overview on Pathophysiology and Newer Approaches to Treatment of Peripheral Neuropathies

Author keywords

Diabetic Neuropathy; Gabapentin; Neuropathic Pain; Peripheral Neuropathy; Pregabalin

Indexed keywords

ADENOSINE; AMANTADINE; ANTICONVULSIVE AGENT; ANTIDEPRESSANT AGENT; ANTINEOPLASTIC AGENT; CANNABINOID; CARBAMAZEPINE; CHOLECYSTOKININ RECEPTOR BLOCKING AGENT; DEXTROMETHORPHAN; GABAPENTIN; GLYCINE; ISOSORBIDE DINITRATE; KETAMINE; LAMOTRIGINE; LEVACECARNINE; LIDOCAINE; N METHYL DEXTRO ASPARTIC ACID RECEPTOR BLOCKING AGENT; NERVE GROWTH FACTOR; NONSTEROID ANTIINFLAMMATORY AGENT; OPIATE; PHENYTOIN; PREGABALIN; RNA DIRECTED DNA POLYMERASE INHIBITOR; SEROTONIN NORADRENALIN REUPTAKE INHIBITOR; SEROTONIN UPTAKE INHIBITOR; THIOCTIC ACID; TOPIRAMATE; TRICYCLIC ANTIDEPRESSANT AGENT; UNINDEXED DRUG; VALPROIC ACID; ACETYLCARNITINE; NARCOTIC ANALGESIC AGENT; NOOTROPIC AGENT;

EID: 35348916612     PISSN: 11727047     EISSN: 11791934     Source Type: Journal    
DOI: 10.2165/00023210-200721001-00002     Document Type: Review
Times cited : (37)

References (53)
  • 3
    • 33748928982 scopus 로고    scopus 로고
    • Is pain ever normal?
    • PID: 16988565
    • Cronje RJ, Williamson OD. Is pain ever normal? Clin J Pain 2006; 22(8): 692–9
    • (2006) Clin J Pain , vol.22 , Issue.8 , pp. 692-699
    • Cronje, R.J.1    Williamson, O.D.2
  • 4
    • 0035933188 scopus 로고    scopus 로고
    • TNFα expression in painful and nonpainful neuropathies
    • COI: 1:STN:280:DC%2BD3M3pt12isQ%3D%3D
    • Empl M, Renaud S, Erne B, et al. TNFα expression in painful and nonpainful neuropathies. Neurology 2001; 56(10): 1371–7
    • (2001) Neurology , vol.56 , Issue.10 , pp. 1371-1377
    • Empl, M.1    Renaud, S.2    Erne, B.3
  • 5
    • 0036006118 scopus 로고    scopus 로고
    • Endoneurial remodeling by TNFα and TNFα-releasing proteases: a spatial and temporal co-localization study in painful neuropathy
    • COI: 1:CAS:528:DC%2BD38XjtFWjt7g%3D, PID: 11939349
    • Shubayev VI, Myers RR. Endoneurial remodeling by TNFα and TNFα-releasing proteases: a spatial and temporal co-localization study in painful neuropathy. J Peripher Nerv Syst 2002; 7(1): 28–36
    • (2002) J Peripher Nerv Syst , vol.7 , Issue.1 , pp. 28-36
    • Shubayev, V.I.1    Myers, R.R.2
  • 6
    • 0036499160 scopus 로고    scopus 로고
    • Anterograde TNFα transport from rat dorsal root ganglion to spinal cord and injured sciatic nerve
    • COI: 1:CAS:528:DC%2BD38Xht1ags7o%3D, PID: 11849773
    • Shubayev VI, Myers RR. Anterograde TNFα transport from rat dorsal root ganglion to spinal cord and injured sciatic nerve. Neurosci Lett 2002; 320(1–2): 99–101
    • (2002) Neurosci Lett , vol.320 , Issue.1-2 , pp. 99-101
    • Shubayev, V.I.1    Myers, R.R.2
  • 7
    • 0035038779 scopus 로고    scopus 로고
    • Central neuroplasticity and pathological pain
    • COI: 1:STN:280:DC%2BD383mtVygsg%3D%3D, PID: 12000018
    • Melzack R, Coderre TJ, Katz J, et al. Central neuroplasticity and pathological pain. Ann N Y Acad Sci 2001; 933: 157–74
    • (2001) Ann N Y Acad Sci , vol.933 , pp. 157-174
    • Melzack, R.1    Coderre, T.J.2    Katz, J.3
  • 8
    • 0345445898 scopus 로고    scopus 로고
    • Advances in neuropathic pain: diagnosis, mechanisms, and treatment recommendations
    • PID: 14623723
    • Dworkin RH, Backonja M, Rowbotham MC, et al. Advances in neuropathic pain: diagnosis, mechanisms, and treatment recommendations. Arch Neurol 2003; 60(11): 1524–34
    • (2003) Arch Neurol , vol.60 , Issue.11 , pp. 1524-1534
    • Dworkin, R.H.1    Backonja, M.2    Rowbotham, M.C.3
  • 9
    • 33646192298 scopus 로고    scopus 로고
    • Non-epilepsy uses of antiepilepsy drugs
    • COI: 1:CAS:528:DC%2BD28XlvVOhtbg%3D, PID: 16531624
    • Zaremba PD, Bialek M, Blaszczyk B, et al. Non-epilepsy uses of antiepilepsy drugs. Pharmacol Rep 2006; 58(1): 1–12
    • (2006) Pharmacol Rep , vol.58 , Issue.1 , pp. 1-12
    • Zaremba, P.D.1    Bialek, M.2    Blaszczyk, B.3
  • 10
    • 0034527450 scopus 로고    scopus 로고
    • The pharmacological basis of contemporary pain management
    • COI: 1:CAS:528:DC%2BD3MXisVWrtg%3D%3D, PID: 11150596
    • MacPherson RD. The pharmacological basis of contemporary pain management. Pharmacol Ther 2000; 88(2): 163–85
    • (2000) Pharmacol Ther , vol.88 , Issue.2 , pp. 163-185
    • MacPherson, R.D.1
  • 11
    • 17144363207 scopus 로고    scopus 로고
    • Current trends in neuropathic pain treatments with special reference to fibromyalgia
    • PID: 15902759
    • Offenbaecher M, Ackenheil M. Current trends in neuropathic pain treatments with special reference to fibromyalgia. CNS Spectr 2005; 10(4): 285–97
    • (2005) CNS Spectr , vol.10 , Issue.4 , pp. 285-297
    • Offenbaecher, M.1    Ackenheil, M.2
  • 12
    • 0242509095 scopus 로고    scopus 로고
    • Newer antiepileptic drugs: possible uses in the treatment of neuropathic pain and migraine
    • COI: 1:CAS:528:DC%2BD3sXpvVGksLs%3D, PID: 14667954
    • Pappagallo M. Newer antiepileptic drugs: possible uses in the treatment of neuropathic pain and migraine. Clin Ther 2003; 25(10): 2506–38
    • (2003) Clin Ther , vol.25 , Issue.10 , pp. 2506-2538
    • Pappagallo, M.1
  • 13
    • 0034750718 scopus 로고    scopus 로고
    • Gabapentin in postherpetic neuralgia: a randomised, double blind, placebo controlled study
    • COI: 1:CAS:528:DC%2BD3MXnvFCrsLc%3D, PID: 11690735
    • Rice AS, Maton S. Gabapentin in postherpetic neuralgia: a randomised, double blind, placebo controlled study. Pain 2001; 94(2): 215–24
    • (2001) Pain , vol.94 , Issue.2 , pp. 215-224
    • Rice, A.S.1    Maton, S.2
  • 14
    • 0032477305 scopus 로고    scopus 로고
    • Gabapentin for the treatment of postherpetic neuralgia: a randomized controlled trial
    • COI: 1:CAS:528:DyaK1cXotVajs7k%3D, PID: 9846778
    • Rowbotham M, Harden N, Stacey B, et al. Gabapentin for the treatment of postherpetic neuralgia: a randomized controlled trial. JAMA 1998; 280(21): 1837–42
    • (1998) JAMA , vol.280 , Issue.21 , pp. 1837-1842
    • Rowbotham, M.1    Harden, N.2    Stacey, B.3
  • 15
    • 0030796031 scopus 로고    scopus 로고
    • Gabapentin (Neurontin) and S-(+)-3-isobutylgaba represent a novel class of selective antihyperalgesic agents
    • COI: 1:CAS:528:DyaK2sXlslaqtrw%3D, PID: 9283683
    • Field MJ, Oles RJ, Lewis AS, et al. Gabapentin (Neurontin) and S-(+)-3-isobutylgaba represent a novel class of selective antihyperalgesic agents. Br J Pharmacol 1997; 121(8): 1513–22
    • (1997) Br J Pharmacol , vol.121 , Issue.8 , pp. 1513-1522
    • Field, M.J.1    Oles, R.J.2    Lewis, A.S.3
  • 16
    • 0036252330 scopus 로고    scopus 로고
    • Gabapentin: pharmacology and its use in pain management
    • COI: 1:CAS:528:DC%2BD38Xkt1Khsbc%3D, PID: 11966555
    • Rose MA, Kam PC. Gabapentin: pharmacology and its use in pain management. Anaesthesia 2002; 57(5): 451–62
    • (2002) Anaesthesia , vol.57 , Issue.5 , pp. 451-462
    • Rose, M.A.1    Kam, P.C.2
  • 17
    • 10444245040 scopus 로고    scopus 로고
    • Pregabalin relieves symptoms of painful diabetic neuropathy: a randomized controlled trial
    • COI: 1:STN:280:DC%2BD2cnitFOjtA%3D%3D, PID: 15596757
    • Lesser H, Sharma U, LaMoreaux L, et al. Pregabalin relieves symptoms of painful diabetic neuropathy: a randomized controlled trial. Neurology 2004; 63(11): 2104–10
    • (2004) Neurology , vol.63 , Issue.11 , pp. 2104-2110
    • Lesser, H.1    Sharma, U.2    LaMoreaux, L.3
  • 18
    • 16844380945 scopus 로고    scopus 로고
    • Relief of painful diabetic peripheral neuropathy with pregabalin: a randomized, placebo-controlled trial
    • COI: 1:CAS:528:DC%2BD2MXjtVyku7k%3D, PID: 15820913
    • Richter RW, Portenoy R, Sharma U, et al. Relief of painful diabetic peripheral neuropathy with pregabalin: a randomized, placebo-controlled trial. J Pain 2005; 6(4): 253–60
    • (2005) J Pain , vol.6 , Issue.4 , pp. 253-260
    • Richter, R.W.1    Portenoy, R.2    Sharma, U.3
  • 19
    • 3843088696 scopus 로고    scopus 로고
    • Pregabalin for the treatment of painful diabetic peripheral neuropathy: a double-blind, placebo-controlled trial
    • COI: 1:CAS:528:DC%2BD2cXmt1WrsLw%3D, PID: 15288403
    • Rosenstock J, Tuchman M, LaMoreaux L, et al. Pregabalin for the treatment of painful diabetic peripheral neuropathy: a double-blind, placebo-controlled trial. Pain 2004; 110(3): 628–38
    • (2004) Pain , vol.110 , Issue.3 , pp. 628-638
    • Rosenstock, J.1    Tuchman, M.2    LaMoreaux, L.3
  • 20
    • 22144491163 scopus 로고    scopus 로고
    • Zonisamide in the treatment of painful diabetic neuropathy: a randomized, double-blind, placebo-controlled pilot study
    • PID: 15972086
    • Atli A, Dogra S. Zonisamide in the treatment of painful diabetic neuropathy: a randomized, double-blind, placebo-controlled pilot study. Pain Med 2005; 6(3): 225–34
    • (2005) Pain Med , vol.6 , Issue.3 , pp. 225-234
    • Atli, A.1    Dogra, S.2
  • 21
    • 27144484863 scopus 로고    scopus 로고
    • Centrally mediated antihyperalgesic and antiallodynic effects of zonisamide following partial nerve injury in the mouse
    • COI: 1:CAS:528:DC%2BD2MXhtFemurfI, PID: 16217643
    • Tanabe M, Sakaue A, Takasu K, et al. Centrally mediated antihyperalgesic and antiallodynic effects of zonisamide following partial nerve injury in the mouse. Naunyn Schmiedebergs Arch Pharmacol 2005; 372(2): 107–14
    • (2005) Naunyn Schmiedebergs Arch Pharmacol , vol.372 , Issue.2 , pp. 107-114
    • Tanabe, M.1    Sakaue, A.2    Takasu, K.3
  • 22
    • 0034860990 scopus 로고    scopus 로고
    • Adjunctive agents in the management of chronic pain
    • COI: 1:CAS:528:DC%2BD3MXnt1Wgsbg%3D, PID: 11560197
    • Guay DR. Adjunctive agents in the management of chronic pain. Pharmacotherapy 2001; 21(9): 1070–81
    • (2001) Pharmacotherapy , vol.21 , Issue.9 , pp. 1070-1081
    • Guay, D.R.1
  • 23
    • 3042815542 scopus 로고    scopus 로고
    • Painful peripheral neuropathy and its nonsurgical treatment
    • COI: 1:CAS:528:DC%2BD2cXmtl2gtb4%3D, PID: 15221874
    • Wolfe GI, Trivedi JR. Painful peripheral neuropathy and its nonsurgical treatment. Muscle Nerve 2004; 30(1): 3–19
    • (2004) Muscle Nerve , vol.30 , Issue.1 , pp. 3-19
    • Wolfe, G.I.1    Trivedi, J.R.2
  • 24
    • 1242293159 scopus 로고    scopus 로고
    • Evaluation of efficacy of the perioperative administration of venlafaxine XR in the prevention of postmastectomy pain syndrome
    • COI: 1:CAS:528:DC%2BD2cXisFKns7g%3D, PID: 15157037
    • Reuben SS, Makari-Judson G, Lurie SD. Evaluation of efficacy of the perioperative administration of venlafaxine XR in the prevention of postmastectomy pain syndrome. J Pain Symptom Manage 2004; 27(2): 133–9
    • (2004) J Pain Symptom Manage , vol.27 , Issue.2 , pp. 133-139
    • Reuben, S.S.1    Makari-Judson, G.2    Lurie, S.D.3
  • 25
    • 20444464304 scopus 로고    scopus 로고
    • Duloxetine vs placebo in patients with painful diabetic neuropathy
    • COI: 1:CAS:528:DC%2BD2MXlsFGhsb0%3D, PID: 15927394
    • Goldstein DJ, Lu Y, Detke MJ, et al. Duloxetine vs placebo in patients with painful diabetic neuropathy. Pain 2005; 116(1–2): 109–18
    • (2005) Pain , vol.116 , Issue.1-2 , pp. 109-118
    • Goldstein, D.J.1    Lu, Y.2    Detke, M.J.3
  • 26
    • 28444459170 scopus 로고    scopus 로고
    • A double-blind, randomized multicenter trial comparing duloxetine with placebo in the management of diabetic peripheral neuropathic pain
    • PID: 16266355
    • Raskin J, Pritchett YL, Wang F, et al. A double-blind, randomized multicenter trial comparing duloxetine with placebo in the management of diabetic peripheral neuropathic pain. Pain Med 2005; 6(5): 346–56
    • (2005) Pain Med , vol.6 , Issue.5 , pp. 346-356
    • Raskin, J.1    Pritchett, Y.L.2    Wang, F.3
  • 27
    • 3843053823 scopus 로고    scopus 로고
    • Venlafaxine extended release in the treatment of painful diabetic neuropathy: a double-blind, placebo-controlled study
    • COI: 1:CAS:528:DC%2BD2cXmt1WrsLs%3D, PID: 15288411
    • Rowbotham MC, Goli V, Kunz NR, et al. Venlafaxine extended release in the treatment of painful diabetic neuropathy: a double-blind, placebo-controlled study. Pain 2004; 110(3): 697–706
    • (2004) Pain , vol.110 , Issue.3 , pp. 697-706
    • Rowbotham, M.C.1    Goli, V.2    Kunz, N.R.3
  • 28
    • 0347185884 scopus 로고    scopus 로고
    • Venlafaxine versus imipramine in painful polyneuropathy: a randomized, controlled trial
    • COI: 1:CAS:528:DC%2BD3sXisFCqurw%3D, PID: 12707430
    • Sindrup SH, Bach FW, Madsen C, et al. Venlafaxine versus imipramine in painful polyneuropathy: a randomized, controlled trial. Neurology 2003; 60(8): 1284–9
    • (2003) Neurology , vol.60 , Issue.8 , pp. 1284-1289
    • Sindrup, S.H.1    Bach, F.W.2    Madsen, C.3
  • 29
    • 0038161131 scopus 로고    scopus 로고
    • Tramadol in postherpetic neuralgia: a randomized, double-blind, placebo-controlled trial
    • COI: 1:CAS:528:DC%2BD3sXltF2nsr4%3D, PID: 12855342
    • Boureau F, Legallicier P, Kabir-Ahmadi M. Tramadol in postherpetic neuralgia: a randomized, double-blind, placebo-controlled trial. Pain 2003; 104(1–2): 323–31
    • (2003) Pain , vol.104 , Issue.1-2 , pp. 323-331
    • Boureau, F.1    Legallicier, P.2    Kabir-Ahmadi, M.3
  • 30
    • 0031779616 scopus 로고    scopus 로고
    • Double-blind randomized trial of tramadol for the treatment of the pain of diabetic neuropathy
    • COI: 1:CAS:528:DyaK1cXktFOisbk%3D, PID: 9633738
    • Harati Y, Gooch C, Swenson M, et al. Double-blind randomized trial of tramadol for the treatment of the pain of diabetic neuropathy. Neurology 1998; 50(6): 1842–6
    • (1998) Neurology , vol.50 , Issue.6 , pp. 1842-1846
    • Harati, Y.1    Gooch, C.2    Swenson, M.3
  • 31
    • 0032877110 scopus 로고    scopus 로고
    • Tramadol relieves pain and allodynia in polyneuropathy: a randomised, double-blind, controlled trial
    • COI: 1:CAS:528:DyaK1MXmt1ekurw%3D, PID: 10506675
    • Sindrup SH, Andersen G, Madsen C, et al. Tramadol relieves pain and allodynia in polyneuropathy: a randomised, double-blind, controlled trial. Pain 1999; 83(1): 85–90
    • (1999) Pain , vol.83 , Issue.1 , pp. 85-90
    • Sindrup, S.H.1    Andersen, G.2    Madsen, C.3
  • 32
    • 3142736514 scopus 로고    scopus 로고
    • New treatments for diabetic neuropathy: symptomatic treatments
    • PID: 14611741
    • Krishnan ST, Rayman G. New treatments for diabetic neuropathy: symptomatic treatments. Curr Diab Rep 2003; 3(6): 459–67
    • (2003) Curr Diab Rep , vol.3 , Issue.6 , pp. 459-467
    • Krishnan, S.T.1    Rayman, G.2
  • 33
    • 0642316020 scopus 로고    scopus 로고
    • VR1 receptor modulators as potential drugs for neuropathic pain
    • COI: 1:CAS:528:DC%2BD3sXotlWjsbs%3D, PID: 14529514
    • Lopez-Rodriguez ML, Viso A, Ortega-Gutierrez S. VR1 receptor modulators as potential drugs for neuropathic pain. Mini Rev Med Chem 2003; 3(7): 729–48
    • (2003) Mini Rev Med Chem , vol.3 , Issue.7 , pp. 729-748
    • Lopez-Rodriguez, M.L.1    Viso, A.2    Ortega-Gutierrez, S.3
  • 34
    • 0035042343 scopus 로고    scopus 로고
    • Relation between homocysteinaemia and diabetic neuropathy in patients with type 2 diabetes mellitus
    • COI: 1:CAS:528:DC%2BD3MXjslKns7c%3D, PID: 11318838
    • Ambrosch A, Dierkes J, Lobmann R, et al. Relation between homocysteinaemia and diabetic neuropathy in patients with type 2 diabetes mellitus. Diabet Med 2001; 18(3): 185–92
    • (2001) Diabet Med , vol.18 , Issue.3 , pp. 185-192
    • Ambrosch, A.1    Dierkes, J.2    Lobmann, R.3
  • 35
    • 33745590029 scopus 로고    scopus 로고
    • Breakthrough medical approach in the management of patients with diabetic neuropathy: A compendium of cases studies and clinical decision making
    • Nov/Dec
    • Allie D, Rodriguez G, Jacobs A, et al. Breakthrough medical approach in the management of patients with diabetic neuropathy: a compendium of cases studies and clinical decision making. Vasc Dis Manage 2005; Suppl Nov/Dec: 1S-9S
    • (2005) Vasc Dis Manage , pp. 1S-9S
    • Allie, D.1    Rodriguez, G.2    Jacobs, A.3
  • 36
    • 0042405193 scopus 로고    scopus 로고
    • Diabetic autonomic neuropathy
    • PID: 12716821
    • Vinik AI, Maser RE, Mitchell BD, et al. Diabetic autonomic neuropathy. Diabetes Care 2003; 26(5): 1553–79
    • (2003) Diabetes Care , vol.26 , Issue.5 , pp. 1553-1579
    • Vinik, A.I.1    Maser, R.E.2    Mitchell, B.D.3
  • 37
    • 0142213243 scopus 로고    scopus 로고
    • Comparative neuropathology and diabetic autonomic neuropathy
    • PID: 14578168
    • Mizisin AP. Comparative neuropathology and diabetic autonomic neuropathy. Am J Pathol 2003; 163(5): 1703–6
    • (2003) Am J Pathol , vol.163 , Issue.5 , pp. 1703-1706
    • Mizisin, A.P.1
  • 38
    • 23644441128 scopus 로고    scopus 로고
    • Symptomatic and neurophysiological responses of paclitaxel- or cisplatin-induced neuropathy to oral acetyl-L-carnitine
    • COI: 1:CAS:528:DC%2BD2MXns1Wit7s%3D, PID: 16039110
    • Bianchi G, Vitali G, Caraceni A, et al. Symptomatic and neurophysiological responses of paclitaxel- or cisplatin-induced neuropathy to oral acetyl-L-carnitine. Eur J Cancer 2005; 41(12): 1746–50
    • (2005) Eur J Cancer , vol.41 , Issue.12 , pp. 1746-1750
    • Bianchi, G.1    Vitali, G.2    Caraceni, A.3
  • 39
    • 0030390397 scopus 로고    scopus 로고
    • HIV-1 infection and carnitine metabolism
    • Famularo G, De Simone C, et al. HIV-1 infection and carnitine metabolism. J Immunol Immunopharmacol 1996; XVI(3–4): 70–3
    • (1996) J Immunol Immunopharmacol , vol.16 , Issue.3-4 , pp. 70-73
    • Famularo, G.1    De Simone, C.2
  • 40
    • 33644772837 scopus 로고    scopus 로고
    • Long-term effect of acetyl-L-carnitine for antiretroviral toxic neuropathy
    • PID: 16566084
    • Herzmann C, Johnson MA, Youle M. Long-term effect of acetyl-L-carnitine for antiretroviral toxic neuropathy. HIV Clin Trials 2005; 6(6): 344–50
    • (2005) HIV Clin Trials , vol.6 , Issue.6 , pp. 344-350
    • Herzmann, C.1    Johnson, M.A.2    Youle, M.3
  • 41
    • 0031018842 scopus 로고    scopus 로고
    • Mitochondria alterations and dramatic tendency to undergo apoptosis in peripheral blood lymphocytes during acute HIV syndrome
    • COI: 1:STN:280:DyaK2s3msVWquw%3D%3D, PID: 9110071
    • Cossarizza A, Mussini C, Mongiardo N, et al. Mitochondria alterations and dramatic tendency to undergo apoptosis in peripheral blood lymphocytes during acute HIV syndrome. AIDS 1997; 11(1): 19–26
    • (1997) AIDS , vol.11 , Issue.1 , pp. 19-26
    • Cossarizza, A.1    Mussini, C.2    Mongiardo, N.3
  • 42
    • 0031032991 scopus 로고    scopus 로고
    • Acetyl-carnitine deficiency in AIDS patients with neurotoxicity on treatment with antiretroviral nucleoside analogues
    • COI: 1:CAS:528:DyaK2sXhs1Omsb0%3D
    • Famularo G, Moretti S, Marcellini S, et al. Acetyl-carnitine deficiency in AIDS patients with neurotoxicity on treatment with antiretroviral nucleoside analogues. AIDS 1997; 11(2): 185–90
    • (1997) AIDS , vol.11 , Issue.2 , pp. 185-190
    • Famularo, G.1    Moretti, S.2    Marcellini, S.3
  • 43
    • 22944485043 scopus 로고    scopus 로고
    • Acetyl-L-carnitine prevents and reverts experimental chronic neurotoxicity induced by oxaliplatin, without altering its antitumor properties
    • COI: 1:CAS:528:DC%2BD2MXpt1Wkurk%3D
    • Ghirardi O, Lo Giudice P, Pisano C, et al. Acetyl-L-carnitine prevents and reverts experimental chronic neurotoxicity induced by oxaliplatin, without altering its antitumor properties. Anticancer Res 2005; 25(4): 2681–7
    • (2005) Anticancer Res , vol.25 , Issue.4 , pp. 2681-2687
    • Ghirardi, O.1    Lo Giudice, P.2    Pisano, C.3
  • 44
    • 0345060438 scopus 로고    scopus 로고
    • Paclitaxel and cisplatin-induced neurotoxicity: a protective role of acetyl-L-carnitine
    • COI: 1:CAS:528:DC%2BD3sXpsVeju7k%3D, PID: 14654561
    • Pisano C, Pratesi G, Laccabue D, et al. Paclitaxel and cisplatin-induced neurotoxicity: a protective role of acetyl-L-carnitine. Clin Cancer Res 2003; 9(15): 5756–67
    • (2003) Clin Cancer Res , vol.9 , Issue.15 , pp. 5756-5767
    • Pisano, C.1    Pratesi, G.2    Laccabue, D.3
  • 45
    • 0027104083 scopus 로고
    • Levocarnitine acetyl stimulates peripheral nerve regeneration and neuromuscular junction remodelling following sciatic nerve injury
    • PID: 1338731
    • De Angelis C, Scarfo C, Falcinelli M, et al. Levocarnitine acetyl stimulates peripheral nerve regeneration and neuromuscular junction remodelling following sciatic nerve injury. Int J Clin Pharmacol Res 1992; 12(5–6): 269–79
    • (1992) Int J Clin Pharmacol Res , vol.12 , Issue.5-6 , pp. 269-279
    • De Angelis, C.1    Scarfo, C.2    Falcinelli, M.3
  • 46
    • 33644783056 scopus 로고    scopus 로고
    • Acetyl-1-carnitine in the treatment of painful antiretroviral toxic neuropathy in human immunodeficiency virus patients: an open label study
    • COI: 1:CAS:528:DC%2BD28XjvV2ms7o%3D, PID: 16519785
    • Osio M, Muscia F, Zampini L, et al. Acetyl-1-carnitine in the treatment of painful antiretroviral toxic neuropathy in human immunodeficiency virus patients: an open label study. J Peripher Nerv Syst 2006; 11(1): 72–6
    • (2006) J Peripher Nerv Syst , vol.11 , Issue.1 , pp. 72-76
    • Osio, M.1    Muscia, F.2    Zampini, L.3
  • 47
    • 33747611426 scopus 로고    scopus 로고
    • Transcriptional regulation of metabotropic glutamate receptor 2/3 expression by the NF-kappaB pathway in primary dorsal root ganglia neurons: a possible mechanism for the analgesic effect of L-acetylcarnitine
    • PID: 16764720
    • Chiechio S, Copani A, De Petris L, et al. Transcriptional regulation of metabotropic glutamate receptor 2/3 expression by the NF-kappaB pathway in primary dorsal root ganglia neurons: a possible mechanism for the analgesic effect of L-acetylcarnitine. Mol Pain 2006; 2: 20
    • (2006) Mol Pain , vol.2 , pp. 20
    • Chiechio, S.1    Copani, A.2    De Petris, L.3
  • 48
    • 18344385695 scopus 로고    scopus 로고
    • L-Acetylcarnitine induces analgesia by selectively up-regulating mGlu2 metabotropic glutamate receptors
    • COI: 1:CAS:528:DC%2BD38XjtlGltb0%3D
    • Chiechio S, Caricasole A, Barletta E, et al. L-Acetylcarnitine induces analgesia by selectively up-regulating mGlu2 metabotropic glutamate receptors. Mol Pharmacol 2002; 61(5): 989–96
    • (2002) Mol Pharmacol , vol.61 , Issue.5 , pp. 989-996
    • Chiechio, S.1    Caricasole, A.2    Barletta, E.3
  • 49
    • 0037965156 scopus 로고    scopus 로고
    • Acetyl-L-carnitine (levacecarnine) in the treatment of diabetic neuropathy: a long-term, randomised, double-blind, placebo-controlled study
    • PID: 12455197
    • De Grandis D, Minardi C. Acetyl-L-carnitine (levacecarnine) in the treatment of diabetic neuropathy: a long-term, randomised, double-blind, placebo-controlled study. Drugs R D 2002; 3(4): 223–31
    • (2002) Drugs R D , vol.3 , Issue.4 , pp. 223-231
    • De Grandis, D.1    Minardi, C.2
  • 50
    • 11844273799 scopus 로고    scopus 로고
    • Acetyl-L-carnitine improves pain, nerve regeneration, and vibratory perception in patients with chronic diabetic neuropathy: an analysis of two randomized placebo-controlled trials
    • COI: 1:CAS:528:DC%2BD2MXhtFWms7g%3D
    • Sima AA, Calvani M, Mehra M, et al. Acetyl-L-carnitine improves pain, nerve regeneration, and vibratory perception in patients with chronic diabetic neuropathy: an analysis of two randomized placebo-controlled trials. Diabetes Care 2005; 28(1): 89–94
    • (2005) Diabetes Care , vol.28 , Issue.1 , pp. 89-94
    • Sima, A.A.1    Calvani, M.2    Mehra, M.3
  • 51
    • 3843077471 scopus 로고    scopus 로고
    • Acetyl-1-carnitine: a pathogenesis based treatment for HIV-associated antiretroviral toxic neuropathy
    • COI: 1:CAS:528:DC%2BD2cXlsVWgsL4%3D
    • Hart AM, Wilson AD, Montovani C, et al. Acetyl-1-carnitine: a pathogenesis based treatment for HIV-associated antiretroviral toxic neuropathy. AIDS 2004; 18(11): 1549–60
    • (2004) AIDS , vol.18 , Issue.11 , pp. 1549-1560
    • Hart, A.M.1    Wilson, A.D.2    Montovani, C.3
  • 52
    • 34247873189 scopus 로고    scopus 로고
    • A double-blind, parallel-group, placebo-controlled, multicentre study of acetyl l-carnitine in the symptomatic treatment of antiretroviral toxic neuropathy in patients with HIV-1 infection
    • COI: 1:CAS:528:DC%2BD2sXmtFKhtbs%3D, PID: 17461852
    • Youle M, Osio M; on behalf of the ALCAR Study Group. A double-blind, parallel-group, placebo-controlled, multicentre study of acetyl l-carnitine in the symptomatic treatment of antiretroviral toxic neuropathy in patients with HIV-1 infection. HIV Med 2007 May; 8(4): 241–50
    • (2007) HIV Med , vol.8 , Issue.4 , pp. 241-250
    • Youle, M.1    Osio, M.A.S.G.2
  • 53
    • 18944404875 scopus 로고    scopus 로고
    • A pilot study on the effect of acetyl-L-carnitine in paclitaxel- and cisplatin-induced peripheral neuropathy
    • COI: 1:CAS:528:DC%2BD2MXmtVOmsb4%3D
    • Maestri A, De Pasquale Ceratti A, Cundari S, et al. A pilot study on the effect of acetyl-L-carnitine in paclitaxel- and cisplatin-induced peripheral neuropathy. Tumori 2005; 91(2): 135–8
    • (2005) Tumori , vol.91 , Issue.2 , pp. 135-138
    • Maestri, A.1    De Pasquale Ceratti, A.2    Cundari, S.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.