Effects of rhBMP-2 on cortical strut allograft healing to the femur in revision total hip arthroplasties: An experimental study

International Orthopaedics

Volumn 31, Issue 5, 2007, Pages 605-611

  Wu, Li Dong ^a   Xiong, Yan ^a   Yu, Hua Chen ^a  

^a ZHEJIANG UNIVERSITY SCHOOL OF MEDICINE   (China)

Author keywords

[No Author keywords available]

Indexed keywords

BONE MORPHOGENETIC PROTEIN 2; GELATIN;

ALLOGRAFT; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; BONE RADIOGRAPHY; BONE REMODELING; COMPOSITE MATERIAL; CONTROLLED STUDY; CORTICAL BONE; EXPERIMENTAL STUDY; FLUORESCENCE MICROSCOPY; FRACTURE HEALING; IMPLANT; NONHUMAN; PRIORITY JOURNAL; RABBIT; TOTAL HIP PROSTHESIS;

ANIMALS; ARTHROPLASTY, REPLACEMENT, HIP; BONE MORPHOGENETIC PROTEINS; FEMUR; FRACTURE HEALING; RABBITS; RECOMBINANT PROTEINS; TRANSFORMING GROWTH FACTOR BETA; TRANSPLANTATION, HOMOLOGOUS;

EID: 35348915994     PISSN: 03412695     EISSN: None     Source Type: Journal    
DOI: 10.1007/s00264-006-0235-3     Document Type: Article

References (30)

1. Barden B, Fitzek JG, Huttegger C, Loer F (2001) Supportive strut grafts for diaphyseal bone defects in revision hip arthroplasty. Clin Orthop Relat Res 387:148-155
2. Barden B, von Knoch M, Fitzek JG, Loer F (2003) Periprosthetic fractures with extensive bone loss treated with onlay strut allografts. Int Orthop 27:164-167
3. Bouxsein ML, Turek TJ, Blake CA, D'Augusta D, Li X, Stevens M, Seeherman HJ, Wozney JM (2001) Recombinant human bone morphogenetic protein-2 accelerates healing in a rabbit ulnar osteotomy model. J Bone Joint Surg [Am] 83:1219-1230
4. Bilic R, Simic P, Jelic M, Stern-Padovan R, Dodig D, van Meerdervoort HP, Martinovic S, Ivankovic D, Pecina M, Vukicevic S (2006) Osteogenic protein-1 (BMP-7) accelerates healing of scaphoid non-union with proximal pole sclerosis. Int Orthop 30:128-134
5. Bucholz RW (2002) Nonallograft osteoconductive bone graft substitutes. Clin Orthop Relat Res 395:44-52
6. Clohisy JC, Calvert G, Tull F, McDonald D, Maloney WJ (2004) Reasons for revision hip surgery: a retrospective review. Clin Orthop Relat Res 429:188-192
7. Cook SD, Barrack RL, Santman M, Patron LP, Salkeld SL, Whitecloud TS 3rd (2000) The Otto Aufranc Award. Strut allograft healing to the femur with recombinant human osteogenic protein-1. Clin Orthop Relat Res 381:47-57
8. Delloye C, Simon P, Nyssen-Behets C, Banse X, Bresler F, Schmitt D (2002) Perforations of cortical bone allografts improve their incorporation. Clin Orthop Relat Res 396:240-247
9. Djapic T, Kusec V, Jelic M, Vukicevic S, Pecina M (2003) Compressed homologous cancellous bone and bone morphogenetic protein (BMP)-7 or bone marrow accelerate healing of long-bone critical defects. Int Orthop 27:326-330
10. Emerson RH Jr, Malinin TI, Cuellar AD, Head WC, Peters PC (1992) Cortical strut allografts in the reconstruction of the femur in revision total hip arthroplasty. A basic science and clinical study. Clin Orthop Relat Res 285:35-44
11. Govender S, Csimma C, Genant HK, Valentin-Opran A, Amit Y, Arbel R, Aro H, Atar D, Bishay M, Borner MG, Chiron P, Choong P, Cinats J, Courtenay B, Feibel R, Geulette B, Gravel C, Haas N, Raschke M, Hammacher E, van der Velde D, Hardy P, Holt M, Josten C, Ketterl RL, Lindeque B, Lob G, Mathevon H, McCoy G, Marsh D, Miller R, Munting E, Oevre S, Nordsletten L, Patel A, Pohl A, Rennie W, Reynders P, Rommens PM, Rondia J, Rossouw WC, Daneel PJ, Ruff S, Ruter A, Santavirta S, Schildhauer TA, Gekle C, Schnettler R, Segal D, Seiler H, Snowdowne RB, Stapert J, Taglang G, Verdonk R, Vogels L, Weckbach A, Wentzensen A, Wisniewski T; BMP-2 Evaluation in Surgery for Tibial Trauma (BESTT) Study Group (2002) Recombinant human bone morphogenetic protein-2 for treatment of open tibial fractures: a prospective, controlled, randomized study of 450 patients. J Bone Joint Surg [Am] 84:2123-2134
12. Gross AE, Wong PK, Hutchison CR, King AE (2003) Onlay cortical strut grafting in revision arthroplasty of the hip. J Arthroplasty 18(3 Suppl 1):104-106
13. Haddad FS, Duncan CP, Berry DJ, Lewallen DG, Gross AE, Chandler HP (2002) Periprosthetic femoral fractures around well-fixed implants: use of cortical onlay allografts with or without a plate. J Bone Joint Surg [Am]84:945-950
14. Haid RW Jr, Branch CL Jr, Alexander JT, Burkus JK (2004) Posterior lumbar interbody fusion using recombinant human bone morphogenetic protein type 2 with cylindrical interbody cages. Spine J 4:527-538
15. Hamadouche M, Blanchat C, Meunier A, Kerboull L, Kerboull M (2002) Histological findings in a proximal femoral structural allograft ten years following revision total hip arthroplasty: a case report. J Bone Joint Surg [Am] 84:269-273
16. Havelin LI, Engesaeter LB, Espehaug B, Furmes O, Lie SA, Vollset SE (2000) The Norwegian arthroplasty register: 11 years and 73,000 arthroplasties. Acta Orthop Scand 71:337-353
17. Head WC, Malinin TI (2000) Results of onlay allografts. Clin Orthop Relat Res 371:108-112
18. Kim YH (2004) Cementless revision hip arthroplasty using strut allografts and primary cementless proximal porous-coated prosthesis. J Arthroplasty 19:573-581
19. Lee FY, Storer S, Hazan EJ, Gebhardt MC, Mankin HJ (2002) Repair of bone allograft fracture using bone morphogenetic protein-2. Clin Orthop Relat Res 397:119-126
20. Lewandrowaski KU, Schollmeier G, Ekkemkamp A, Uhthoff HK, Tomford WW (2001) Incorporation of perforated and demineralized cortical bone allografts. Part I: radiographic and histologic evaluation. Biomed Mater Eng 11:197-207
21. Lewandrowaski KU, Schollmeier G, Ekkemkamp A, Uhthoff HK, Tomford WW (2001) Incorporation of perforated and demineralized cortical bone allografts. Part II: A mechanical and histologic evaluation. Biomed Mater Eng 11:209-219
22. Li RH, Bouxsein ML, Blake CA, D'Augusta D, Kim H, Li XJ, Wozney JM, Seeherman HJ (2003) rhBMP-2 injected in a calcium phosphate paste (alpha-BSM) accelerates healing in the rabbit ulnar osteotomy model. J Orthop Res 21:997-1004
23. Ohyama T, Kubo Y, Iwata H, Taki W (2004) Beta-tricalcium phosphate combined with recombinant human bone morphogenetic protein-2: a substitute for autograft, used for packing interbody fusion cages in the canine lumbar spine. Neurol Med Chir (Tokyo) 44:234-240
24. Pecina M, Giltaij LR, Vukicevic S (2001) Orthopaedic applications of osteogenic protein-1 (BMP-7). Int Orthop 25:203-208
25. Pecina M, Haspl M, Jelic M, Vukicevic S (2003) Repair of a resistant tibial non-union with a recombinant bone morphogenetic protein-7 (rh-BMP-7). Int Orthop 27:320-321
26. Seeherman HJ, Bouxsein M, Kim H, Li R, Li XJ, Aiolova M, Wozney JM (2004) Recombinant human bone morphogenetic protein-2 delivered in an injectable calcium phosphate paste accelerates osteotomy-site healing in a nonhuman primate model. J Bone Joint Surg [Am] 86:1961-1972
27. Taira H, Moreno J, Ripalda P, Forriol F (2004) Radiological and histological analysis of cortical allografts: an experimental study in sheep femora. Arch Orthop Trauma Surg 124:320-325
28. Urist MR (1965) Bone: formation by autoinduction. Science 150:893-899
29. Yamamoto M, Tabata Y, Hong L, Miyamoto S, Hashimoto N, Ikada Y (2000) Bone regeneration by transforming growth factor beta1 released from a biodegradable hydrogel. J Control Release 64:133-142
30. Yamamoto M, Takahashi Y, Tabata Y (2003) Controlled release by biodegradable hydrogels enhances the ectopic bone formation of bone morphogenetic protein. Biomaterials 24:4375-4383