Long-term Potentiation Induces Expanded Movement Representations and Dendritic Hypertrophy in Layer V of Rat Sensorimotor Neocortex

Cerebral Cortex

Volumn 14, Issue 5, 2004, Pages 586-593

  Monfils, Marie H ^a,b   VandenBerg, Penny M ^b   Kleim, Jeffrey A ^b   Teskey, G Campbell ^a,c  

^a UNIVERSITY OF CALGARY   (Canada)

^b UNIVERSITY OF LETHBRIDGE   (Canada)

^c UNIVERSITY OF CALGARY   (Canada)

Author keywords

Caudal forelimb area; Dendritic morphology; Golgi Cox; Long term potentiation; Motor cortex reorganization; Neocortex

Indexed keywords

ANIMAL EXPERIMENT; ARTICLE; BRAIN REGION; CELL STRUCTURE; CONTROLLED STUDY; CORPUS CALLOSUM; CORRELATION ANALYSIS; DENDRITIC CELL; ELECTRODE; EVOKED RESPONSE; FORELIMB; HEMISPHERE; HYPERTROPHY; LEARNING; LONG TERM POTENTIATION; MALE; MOVEMENT (PHYSIOLOGY); NEOCORTEX; NONHUMAN; PRIORITY JOURNAL; PYRAMIDAL NERVE CELL; RAT; SENSORIMOTOR CORTEX; SYNAPSE;

ADAPTATION, PHYSIOLOGICAL; ANIMALS; DENDRITES; ELECTRIC STIMULATION; EVOKED POTENTIALS, MOTOR; FORELIMB; LONG-TERM POTENTIATION; MALE; MOTOR CORTEX; MOVEMENT; NEOCORTEX; NERVE NET; RATS; RATS, LONG-EVANS; SOMATOSENSORY CORTEX;

EID: 1842516012     PISSN: 10473211     EISSN: None     Source Type: Journal    
DOI: 10.1093/cercor/bhh020     Document Type: Article

References (50)

1. Bi GQ, Poo MM (1998) Synaptic modifications in cultured hippocampal neurons: dependence on spike timing, synaptic strength, and postsynaptic cell type. J Neurosci 18:10464-10472.
2. Castro-Alamancos MA, Borrell J (1993) Motor activity induced by disinhibition of the primary motor cortex of the rat is blocked by a non-NMDA glutamate receptor antagonist. Neurosci Lett 150:183-186.
3. Chapman CA, Trepel C, Ivanco TL, Froc DJ, Wilson K, Racine RJ (1998) Changes in field potentials and membrane currents in rat sensorimotor cortex following repeated tetanization of the corpus callosum in vivo. Cereb Cortex 8:730-742.
4. Chen C, Tonegawa S (1997) Molecular genetic analysis of synaptic plasticity, activity-dependent neural development, learning and memory in the mammalian brain. Annu Rev Neurosci 20:157-184.
5. Coleman PD, Riesen AH (1968) Environmental effects on cortical dendritic fields. I. Rearing in the dark. J Anat 102:363-374.
6. Cruikshank SJ, Weinberger NM (1996) Receptive-field plasticity in the adult auditory cortex induced by Hebbian covariance. J Neurosci 16:861-875.
7. de Jonge M, Racine RJ (1987) The development and decay of kindling-induced increases in paired-pulse depression in the dentate gyrus. Brain Res 412:318-328.
8. Donoghue JP, Wise SP (1982) The motor cortex of the rat: cytoarchitecture and microstimulation mapping. J Comp Neurol 212:76-88.
9. Feldman DE, Nicoll RA, Malenka RC, Isaac JTR (1998) Long-term depression at thalamocortical synapses in developing rat somato-sensory cortex. Neuron 21:347-357.
10. Gazzaley A, Kay S, Benson DL (2002) Dendritic spine plasticity in hippocampus. Neuroscience 111:853-862.
11. Gibb, R and Kolb, B (1998) A method for vibratome sectioning of Golgi-Cox stained whole rat brain. J Neurosci Methods 79:1-4.
12. Gioanni, Y and Lamarche, M (1985) A reappraisal of rat motor organization by intracortical microstimulation. Brain Res 344:49-61.
13. Glaser EM, van der Loos H (1981) Analysis of thick brain sections by obverse-reverse computer microscopy: application of a new, high clarity, Golgi-Nissl stain. J Neurosci Methods 4:117-125.
14. Graziano MSA, Taylor CSR, Moore T (2002) Complex movements evoked by microstimulation of precentral cortex. Neuron 34:841-851.
15. Hess G, Donoghue JP (1994) Long-term potentiation of horizontal connections provides a mechanism to reorganize cortical motor maps. J Neurophysiol 71:2543-2457.
16. Hess G, Aizenman CD, Donoghue JP (1996) Conditions for the induction of long-term potentiation in layer II/III horizontal connections of the rat motor cortex. J Neurophysiol 75:1765-1778.
17. Ivanco TL, Racine RJ, Kolb B (2000) Morphology of layer III pyramidal neurons is altered following induction of LTP in sensorimotor cortex of the freely moving rat. Synapse 37:16-22.
18. Jacobs KM, Donoghue JP (1991) Reshaping the cortical motor map by unmasking latent intracortical connections. Science 251:944-947.
19. Jankowska E, Padel Y, Tanaka R (1975) The mode of activation of pyramidal tract cells by intracortical stimuli. J Physiol (Lond) 249:617-636.
20. Jones TA, Chu CJ, Grande LA, Gregory AD (1999) Motor skills training enhances lesion-induced structural plasticity in the motor cortex of adult rats. J Neurosci 19:10153-63.
21. Kirkwood A, Bear MF (1994) Homosynaptic long-term depression in the visual cortex. J Neurosci 14:3404-3412.
22. Kleim JA, Lussnig E, Schwarz ER, Comery TA, Greenough WT (1996) Synaptogenesis, Fos expression in the motor cortex of the adult rat after motor skill learning. J Neurosci 16:4529-4535.
23. Kleim JA, Barbay S, Nudo RJ (1998) Functional reorganization of the rat motor cortex following motor skill learning. J Neurophysiol 80:3321-3325.
24. Kleim JA, Barbay S, Cooper NR, Hogg TM, Reidel CN, Remple MS, Nudo RJ (2002) Motor learning-dependent synaptogenesis is localized to functionally reorganized motor cortex. Neurobiol Learn Mem 77:63-77.
25. Lemon RN, Muir RB, Mantel GW (1987) The effects upon the activity of hand and forearm muscles of intracortical stimulation in the vicinity of corticomotor neurones in the conscious monkey. Exp Brain Res 66:621-637.
26. Metherate R, Ashe JH (1994) Facilitation of a NMDA receptor-mediated EPSP by paired-pulse stimulation in rat neocortex via depression of GABAergic IPSPs. J Physiol (Lond) 481:331-348.
27. Muller D, Toni N, Buchs PA (2000) Spine changes associated with long-term potentiation. Hippocampus 10:596-604.
28. Nudo RJ, Jenkins WM, Merzenich MM (1990) Repetitive microstimulation alters the cortical representation of movements in adult rats. Somatosen Motor Res 7:463-483.
29. Qiu XQ, O'Donoghue DL, Humphrey DR (1990) NMDA antagonists (MK-801) blocks plasticity of motor cortex maps induced by passive limb movement. Soc Neurosci Abstr 16:422.
30. Racine RJ, Tuff L, Zaide J (1975) Kindling, unit discharge and neural plasticity. Can J Neurol Sci 2:395-405.
31. Racine RJ, Chapman CA, Trepel C, Teskey GC, Milgram NW (1995) Post-activation potentiation in the neocortex. IV., Multiple sessions required for induction of long-term potentiation in the chronic preparation. Brain Res 702:87-93.
32. Recanzone GH, Schreiner CE, Merzenich MM (1993) Plasticity in the frequency representation of primary auditory cortex following discrimination training in adult owl monkeys. J Neurosci 13:87-104.
33. Remple MS, Bruneau RM, VandenBerg PM, Goertzen C, Kleim JA (2001) Sensitivity of cortical movement representations to motor experience: evidence that skill learning but not strength training induces cortical reorganization. Behav Brain Res 123:133-141.
34. Rioult-Pedotti MS, Friedman D, Hess G, Donoghue JP (1998) Strengthening of horizontal cortical connections following skill learning. Nat Neurosci 3:230-234.
35. Rioult-Pedotti MS, Friedman D, Donoghue JP (2000) Learning-induced LTP in neocortex. Science 290:533-536.
36. Shepherd GM (1990) The synaptic organization of the brain, 3rd edn. Oxford: Oxford University Press.
37. Sholl DA (1956) The organization of the cerebral cortex. London: Methuen.
38. Stoney SD Jr, Thompson WD, Asanuma H (1968) Excitation of pyramidal tract cells by intracortical microstimulation: effective extent of stimulating current. J Neurophysiol 31:659-669.
39. Swanson LW (1992) Brain maps: structure of the rat brain. New York: Elsevier.
40. Teskey GC, Valentine PA (1998) Post-activation potentiation in the neocortex of awake freely moving rats. Neurosci Biobehav Rev 22:195-207.
41. Teskey GC, Hutchinson JE, Kolb B (1999) Sex differences in cortical plasticity and behavior following anterior cortical kindling in rats. Cereb Cortex 9:675-682.
42. Teskey GC, Monfils MH, VandenBerg PM, Kleim JA (2002) Motor map expansion following repeated cortical and limbic seizures is related to synaptic potentiation. Cereb Cortex 12:98-105.
43. Trepel C, Racine RJ (1998) Long-term potentiation in the neocortex of the adult, freely moving rat. Cereb Cortex 8:719-729.
44. Trepel C, Racin, RJ (2000) GABAergic modulation of neocortical long-term potentiation in the freely moving rat. Synapse 35:120-128.
45. Trommald M, Hulleberg G, Andersen P (1996) Long-term potentiation is associated with new excitatory spine synapses on rat dentate granule cells. Learn Mem 3:218-228.
46. VandenBerg PM, Kleim, JA (2001) Ontogeny of post-ischemic cortical diaschisis. Soc Neurosci Abstr 26:761.9.
47. Vanderwolf CH, Harvey GC, Leung L-WS (1987) Transcallosal evoked potentials in relation to behaviour in the rat: effects of atropine, p-chorophenylalanine, reserpine, scopolamine and trifluoperazine. Behav Brain Res 25:31-48.
48. Werk CM, Chapman CA (2003) Long-term potentiation of polysynaptic responses in layer V of the sensorimotor cortex induced by theta-patterned tetanization in the awake rat. Cereb Cortex 13:500-507.
49. Woolley CS, Gould E, Frankfurt M, McEwen BS (1990) Naturally occurring fluctuation in dendritic spine density on adult hippocampal pyramidal neurons. J Neurosci 10:4035-4039.
50. Zilles K (1985) The cortex of the rat: a stereotaxic atlas. New York: Springer-Verlag.